Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Spinocerebellar ataxia 💬
3件: GRIA1, GRIA2, GRIA3 💬 Perampanel 💬 Perampanel 3件:  2 ,  6 , 144 💬 💬
2 Spinocerebellar ataxia 💬
3件: GRIA1, GRIA2, GRIA3 💬 Talampanel 💬 Talampanel 2件:  2 ,  6  💬 💬
3 Spinocerebellar ataxia 💬
3件: GRIA1, GRIA2, GRIA3 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
4 Spinocerebellar ataxia 💬
8件: GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
5 Spinocerebellar ataxia 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate 2件:  6 , 206 💬 💬
6 Spinocerebellar ataxia 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬 💬
7 Spinocerebellar ataxia 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
8 Spinocerebellar ataxia 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine 3件:  2 ,  4 , 70 💬 💬
9 Spinocerebellar ataxia 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
10 Spinocerebellar ataxia 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Latrepirdine 💬 Latrepirdine 1件:  8  💬 💬
11 Spinocerebellar ataxia 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬 💬
12 Spinocerebellar ataxia 💬
2件: KCNC3, KCND3 💬 Amifampridine 💬 Amifampridine 3件:  3 , 11, 12 💬 💬
13 Spinocerebellar ataxia 💬
2件: KCNC3, KCND3 💬 Dalfampridine 💬 Dalfampridine 5件:  3 ,  4 ,  6 , 13, 14 💬 💬
14 Spinocerebellar ataxia 💬
1件: KCND3 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬 💬
15 Spinocerebellar ataxia 💬
1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
16 Spinocerebellar ataxia 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
17 Spinocerebellar ataxia 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
18 Spinocerebellar ataxia 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
19 Spinocerebellar ataxia 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
20 Spinocerebellar ataxia 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
21 Spinocerebellar ataxia 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
22 Spinocerebellar ataxia 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬
23 Spinocerebellar ataxia 💬
1件: PSMB5 💬 Bortezomib 💬 Bortezomib 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬
24 Spinocerebellar ataxia 💬
1件: PSMB5 💬 Carfilzomib 💬 Carfilzomib 1件: 28 💬 💬
25 Spinocerebellar ataxia 💬
1件: PSMB5 💬 Ixazomib 💬 Ixazomib 5件: 13, 16, 28, 51, 61 💬 💬