Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
2 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
3 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
CDK4 2件: CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 1件: 34 💬
|
4 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR 1件: EGFR 💬
|
Cetuximab Cetuximab 💬
| Cetuximab | 051 2件: 51, 86 💬
|
5 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR 1件: EGFR 💬
|
Erlotinib Erlotinib 💬
| Erlotinib | 094 1件: 94 💬
|
6 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR 1件: EGFR 💬
|
Gefitinib Gefitinib 💬
| Gefitinib | 075 1件: 75 💬
|
7 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR 1件: EGFR 💬
|
Icotinib Icotinib 💬
| Icotinib | 034 1件: 34 💬
|
8 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR 1件: EGFR 💬
|
Lapatinib Lapatinib 💬
| Lapatinib | 034 3件: 34, 74, 75 💬
|
9 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR 1件: EGFR 💬
|
Neratinib Neratinib 💬
| Neratinib | 034 1件: 34 💬
|
10 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
EGFR 1件: EGFR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
11 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
HMOX1 1件: HMOX1 💬
|
Stannsoporfin Stannsoporfin 💬
| Stannsoporfin | 254 1件: 254 💬
|
12 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬
|
Linsitinib Linsitinib 💬
| Linsitinib | 232 1件: 232 💬
|
13 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬
|
Mecasermin Mecasermin 💬
| Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬
|
14 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬
|
Teprotumumab Teprotumumab 💬
| Teprotumumab | 051 1件: 51 💬
|
15 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
KEAP1 1件: KEAP1 💬
|
Dimethyl fumarate Dimethyl fumarate 💬
| Dimethyl fumarate | 013 5件: 13, 49, 51, 86, 296 💬
|
16 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 1件: 34 💬
|
17 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
18 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 1件: 34 💬
|
19 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 1件: 34 💬
|
20 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 4件: 2 , 34, 279, 280 💬
|
21 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MET 1件: MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
22 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
23 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
24 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 1件: 13 💬
|
25 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
NFE2L2 1件: NFE2L2 💬
|
Omaveloxolone Omaveloxolone 💬
| Omaveloxolone | 018 1件: 18 💬
|
26 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
NQO1 1件: NQO1 💬
|
Warfarin Warfarin 💬
| Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
|
27 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
PIK3CA 1件: PIK3CA 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 1件: 138 💬
|
28 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
29 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
PIK3CD 1件: PIK3CD 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
30 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
PRKCB 1件: PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 1件: 168 💬
|
31 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 3件: 51, 85, 222 💬
|