Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Lipid and atherosclerosis 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 1件: 28 💬 💬
2 Lipid and atherosclerosis 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬 💬
3 Lipid and atherosclerosis 💬
4件: CCL2, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
4 Lipid and atherosclerosis 💬
1件: CD40 💬 Bleselumab 💬 Bleselumab 1件: 222 💬 💬
5 Lipid and atherosclerosis 💬
1件: CD40 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬 💬
6 Lipid and atherosclerosis 💬
1件: CD40 💬 Ravagalimab 💬 Ravagalimab 2件: 53, 97 💬 💬
7 Lipid and atherosclerosis 💬
1件: CD40LG 💬 Toralizumab 💬 Toralizumab 1件: 63 💬 💬
8 Lipid and atherosclerosis 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬 💬
9 Lipid and atherosclerosis 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬 💬
10 Lipid and atherosclerosis 💬
2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬
11 Lipid and atherosclerosis 💬
1件: IL1B 💬 Canakinumab 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
12 Lipid and atherosclerosis 💬
1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬 💬
13 Lipid and atherosclerosis 💬
1件: IL1B 💬 Rilonacept 💬 Rilonacept 4件: 51, 106, 107, 266 💬 💬
14 Lipid and atherosclerosis 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬 💬
15 Lipid and atherosclerosis 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬 💬
16 Lipid and atherosclerosis 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬 💬
17 Lipid and atherosclerosis 💬
2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
18 Lipid and atherosclerosis 💬
1件: JAK2 💬 Baricitinib 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
19 Lipid and atherosclerosis 💬
1件: JAK2 💬 Peficitinib 💬 Peficitinib 1件: 46 💬 💬
20 Lipid and atherosclerosis 💬
1件: JAK2 💬 Ruxolitinib 💬 Ruxolitinib 3件: 60, 65, 228 💬 💬
21 Lipid and atherosclerosis 💬
1件: JAK2 💬 Tofacitinib 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
22 Lipid and atherosclerosis 💬
1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬 💬
23 Lipid and atherosclerosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
24 Lipid and atherosclerosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
25 Lipid and atherosclerosis 💬
1件: NFE2L2 💬 Omaveloxolone 💬 Omaveloxolone 1件: 18 💬 💬
26 Lipid and atherosclerosis 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
27 Lipid and atherosclerosis 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
28 Lipid and atherosclerosis 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
29 Lipid and atherosclerosis 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
30 Lipid and atherosclerosis 💬
1件: PPARG 💬 Bocidelpar 💬 Bocidelpar 1件: 113 💬 💬
31 Lipid and atherosclerosis 💬
1件: PPARG 💬 Leriglitazone 💬 Leriglitazone 1件: 20 💬 💬
32 Lipid and atherosclerosis 💬
1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
33 Lipid and atherosclerosis 💬
1件: PPARG 💬 Rosiglitazone 💬 Rosiglitazone 5件: 46, 75, 97, 222, 265 💬 💬
34 Lipid and atherosclerosis 💬
1件: PPARG 💬 Seladelpar 💬 Seladelpar 2件: 93, 94 💬 💬
35 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬
36 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬 💬
37 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
38 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
39 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬 💬
40 Lipid and atherosclerosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
41 Lipid and atherosclerosis 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 2件: 51, 85 💬 💬
42 Lipid and atherosclerosis 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬 💬
43 Lipid and atherosclerosis 💬
3件: RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬 💬
44 Lipid and atherosclerosis 💬
3件: RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬 💬
45 Lipid and atherosclerosis 💬
3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬 💬
46 Lipid and atherosclerosis 💬
1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬 💬
47 Lipid and atherosclerosis 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
48 Lipid and atherosclerosis 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
49 Lipid and atherosclerosis 💬
1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬 💬
50 Lipid and atherosclerosis 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
51 Lipid and atherosclerosis 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
52 Lipid and atherosclerosis 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
53 Lipid and atherosclerosis 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
54 Lipid and atherosclerosis 💬
1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
55 Lipid and atherosclerosis 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
56 Lipid and atherosclerosis 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬 💬
57 Lipid and atherosclerosis 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬 💬
58 Lipid and atherosclerosis 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬