Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Fat digestion and absorption 💬
1件: MTTP 💬 D09637 💬 Lomitapide 1件: 79 💬
2 Fat digestion and absorption 💬
1件: NPC1L1 💬 D01966 💬 Ezetimibe 4件: 49, 79, 93, 260 💬
3 Fatty acid degradation 💬
3件: ADH1A, ADH1B, ADH1C 💬 D00707 💬 Fomepizole 1件: 301 💬
4 Fatty acid degradation 💬
4件: CPT1A, CPT1B, CPT1C, CPT2 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
5 Fatty acid degradation 💬
4件: CPT1A, CPT1B, CPT1C, CPT2 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
6 Fatty acid metabolism 💬
4件: CPT1A, CPT1B, CPT1C, CPT2 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
7 Fatty acid metabolism 💬
4件: CPT1A, CPT1B, CPT1C, CPT2 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
8 Fc epsilon RI signaling pathway 💬
1件: ALOX5 💬 D01773 💬 Oxatomide 1件: 113 💬
9 Fc epsilon RI signaling pathway 💬
1件: ALOX5 💬 D00414 💬 Zileuton 3件: 85, 160, 164 💬
10 Fc epsilon RI signaling pathway 💬
1件: BTK 💬 D10893 💬 Acalabrutinib 2件: 46, 61 💬
11 Fc epsilon RI signaling pathway 💬
1件: BTK 💬 D11478 💬 Branebrutinib 3件: 46, 49, 53 💬
12 Fc epsilon RI signaling pathway 💬
1件: BTK 💬 D11457 💬 Fenebrutinib 1件: 13 💬
13 Fc epsilon RI signaling pathway 💬
1件: BTK 💬 D10223 💬 Ibrutinib 3件: 28, 60, 61 💬
14 Fc epsilon RI signaling pathway 💬
1件: BTK 💬 D12160 💬 Orelabrutinib 3件: 13, 61, 63 💬
15 Fc epsilon RI signaling pathway 💬
1件: BTK 💬 D11422 💬 Zanubrutinib 2件: 300, 331 💬
16 Fc epsilon RI signaling pathway 💬
1件: CSF2 💬 D11343 💬 Otilimab 2件: 46, 256 💬
17 Fc epsilon RI signaling pathway 💬
1件: FCER1A 💬 D05251 💬 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299 💬
18 Fc epsilon RI signaling pathway 💬
1件: FYN 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
19 Fc epsilon RI signaling pathway 💬
1件: FYN 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
20 Fc epsilon RI signaling pathway 💬
1件: IL13 💬 D08857 💬 Anrukinzumab 1件: 97 💬
21 Fc epsilon RI signaling pathway 💬
1件: IL13 💬 D09633 💬 Lebrikizumab 1件: 85 💬
22 Fc epsilon RI signaling pathway 💬
1件: IL13 💬 D09979 💬 Tralokinumab 2件: 85, 97 💬
23 Fc epsilon RI signaling pathway 💬
1件: IL4 💬 D03117 💬 Binetrakin 1件: 46 💬
24 Fc epsilon RI signaling pathway 💬
1件: IL5 💬 D04923 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
25 Fc epsilon RI signaling pathway 💬
1件: IL5 💬 D08985 💬 Reslizumab 2件: 44, 98 💬
26 Fc epsilon RI signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
27 Fc epsilon RI signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
28 Fc epsilon RI signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
29 Fc epsilon RI signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
30 Fc epsilon RI signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
31 Fc epsilon RI signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
32 Fc epsilon RI signaling pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
33 Fc epsilon RI signaling pathway 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
34 Fc epsilon RI signaling pathway 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
35 Fc epsilon RI signaling pathway 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
36 Fc epsilon RI signaling pathway 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
37 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
38 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
39 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
40 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
41 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
42 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
43 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
44 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
45 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
46 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
47 Fc epsilon RI signaling pathway 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
48 Fc gamma R-mediated phagocytosis 💬
1件: MAP2K1 💬 D10604 💬 Binimetinib 1件: 34 💬
49 Fc gamma R-mediated phagocytosis 💬
1件: MAP2K1 💬 D10405 💬 Cobimetinib 1件: 280 💬
50 Fc gamma R-mediated phagocytosis 💬
1件: MAP2K1 💬 D09666 💬 Selumetinib 1件: 34 💬
51 Fc gamma R-mediated phagocytosis 💬
1件: MAP2K1 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
52 Fc gamma R-mediated phagocytosis 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
53 Fc gamma R-mediated phagocytosis 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
54 Fc gamma R-mediated phagocytosis 💬
2件: PRKCD, PRKCE 💬 D09671 💬 Sotrastaurin 1件: 97 💬
55 Fc gamma R-mediated phagocytosis 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
56 Fc gamma R-mediated phagocytosis 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
57 Fc gamma R-mediated phagocytosis 💬
1件: SYK 💬 D09347 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
58 Ferroptosis 💬
1件: HMOX1 💬 D05922 💬 Stannsoporfin 1件: 254 💬
59 Ferroptosis 💬
1件: TFRC 💬 D11812 💬 Pabinafusp alfa 1件: 19 💬
60 Fluid shear stress and atherosclerosis 💬
1件: ACVR2A 💬 D09670 💬 Sotatercept 2件: 86, 284 💬
61 Fluid shear stress and atherosclerosis 💬
2件: ACVR2A, ACVR2B 💬 D10620 💬 Bimagrumab 1件: 15 💬
62 Fluid shear stress and atherosclerosis 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
63 Fluid shear stress and atherosclerosis 💬
1件: BMPR2 💬 D03779 💬 Dibotermin alfa 1件: 34 💬
64 Fluid shear stress and atherosclerosis 💬
4件: CCL2, IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
65 Fluid shear stress and atherosclerosis 💬
1件: HMOX1 💬 D05922 💬 Stannsoporfin 1件: 254 💬
66 Fluid shear stress and atherosclerosis 💬
1件: IFNG 💬 D11120 💬 Emapalumab 2件: 49, 107 💬
67 Fluid shear stress and atherosclerosis 💬
1件: IFNG 💬 D04242 💬 Fontolizumab 1件: 46 💬
68 Fluid shear stress and atherosclerosis 💬
1件: IL1A 💬 D11253 💬 Bermekimab 1件: 51 💬
69 Fluid shear stress and atherosclerosis 💬
2件: IL1A, IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
70 Fluid shear stress and atherosclerosis 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
71 Fluid shear stress and atherosclerosis 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
72 Fluid shear stress and atherosclerosis 💬
2件: IL1R1, IL1R2 💬 D02934 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
73 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D03218 💬 Axitinib 1件: 34 💬
74 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D10062 💬 Cabozantinib 1件: 34 💬
75 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D08881 💬 Cediranib 1件: 34 💬
76 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
77 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
78 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
79 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
80 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
81 Fluid shear stress and atherosclerosis 💬
1件: KDR 💬 D11772 💬 Tesevatinib 1件: 67 💬
82 Fluid shear stress and atherosclerosis 💬
1件: KEAP1 💬 D03846 💬 Dimethyl fumarate 5件: 13, 49, 51, 86, 296 💬
83 Fluid shear stress and atherosclerosis 💬
1件: MAP3K5 💬 D10988 💬 Selonsertib 1件: 86 💬
84 Fluid shear stress and atherosclerosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
85 Fluid shear stress and atherosclerosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
86 Fluid shear stress and atherosclerosis 💬
1件: NFE2L2 💬 D10964 💬 Omaveloxolone 1件: 18 💬
87 Fluid shear stress and atherosclerosis 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
88 Fluid shear stress and atherosclerosis 💬
1件: NQO1 💬 D00564 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
89 Fluid shear stress and atherosclerosis 💬
1件: NQO1 💬 D01280 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
90 Fluid shear stress and atherosclerosis 💬
1件: NQO1 💬 D08682 💬 Warfarin 13件:  6 ,  8 , 13, 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
91 Fluid shear stress and atherosclerosis 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
92 Fluid shear stress and atherosclerosis 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
93 Fluid shear stress and atherosclerosis 💬
2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
94 Fluid shear stress and atherosclerosis 💬
2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
95 Fluid shear stress and atherosclerosis 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
96 Fluid shear stress and atherosclerosis 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
97 Fluid shear stress and atherosclerosis 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
98 Fluid shear stress and atherosclerosis 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
99 Fluid shear stress and atherosclerosis 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
100 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
101 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
102 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
103 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
104 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
105 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
106 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
107 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
108 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
109 Fluid shear stress and atherosclerosis 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
110 Fluid shear stress and atherosclerosis 💬
1件: VEGFA 💬 D09574 💬 Aflibercept 2件: 90, 166 💬
111 Fluid shear stress and atherosclerosis 💬
1件: VEGFA 💬 D06409 💬 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
112 Fluid shear stress and atherosclerosis 💬
1件: VEGFA 💬 D05697 💬 Ranibizumab 4件: 34, 166, 227, 301 💬
113 Focal adhesion 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
114 Focal adhesion 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
115 Focal adhesion 💬
5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
116 Focal adhesion 💬
5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
117 Focal adhesion 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
118 Focal adhesion 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
119 Focal adhesion 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
120 Focal adhesion 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
121 Focal adhesion 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
122 Focal adhesion 💬
2件: EGFR, ERBB2 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
123 Focal adhesion 💬
2件: EGFR, ERBB2 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
124 Focal adhesion 💬
4件: EGFR, ERBB2, FLT4, KDR 💬 D11772 💬 Tesevatinib 1件: 67 💬
125 Focal adhesion 💬
3件: FLT1, FLT4, KDR 💬 D03218 💬 Axitinib 1件: 34 💬
126 Focal adhesion 💬
3件: FLT1, FLT4, KDR 💬 D08881 💬 Cediranib 1件: 34 💬
127 Focal adhesion 💬
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 D10481 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬
128 Focal adhesion 💬
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 D06402 💬 Sunitinib 2件: 28, 34 💬
129 Focal adhesion 💬
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬 D08552 💬 Sunitinib 2件: 28, 34 💬
130 Focal adhesion 💬
3件: FYN, PDGFRB, SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
131 Focal adhesion 💬
3件: FYN, PDGFRB, SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
132 Focal adhesion 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
133 Focal adhesion 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
134 Focal adhesion 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
135 Focal adhesion 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
136 Focal adhesion 💬
1件: ITGA4 💬 D06590 💬 Firategrast 1件: 13 💬
137 Focal adhesion 💬
1件: ITGA4 💬 D06886 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬
138 Focal adhesion 💬
2件: ITGA4, ITGB7 💬 D10540 💬 Abrilumab 2件: 96, 97 💬
139 Focal adhesion 💬
2件: ITGA4, ITGB7 💬 D08083 💬 Vedolizumab 3件: 94, 96, 97 💬
140 Focal adhesion 💬
1件: ITGB7 💬 D09901 💬 Etrolizumab 2件: 96, 97 💬
141 Focal adhesion 💬
2件: KDR, MET 💬 D10062 💬 Cabozantinib 1件: 34 💬
142 Focal adhesion 💬
1件: MAP2K1 💬 D10604 💬 Binimetinib 1件: 34 💬
143 Focal adhesion 💬
1件: MAP2K1 💬 D10405 💬 Cobimetinib 1件: 280 💬
144 Focal adhesion 💬
1件: MAP2K1 💬 D09666 💬 Selumetinib 1件: 34 💬
145 Focal adhesion 💬
1件: MAP2K1 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
146 Focal adhesion 💬
1件: PDGFRA 💬 D01441 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
147 Focal adhesion 💬
1件: PDGFRA 💬 D08066 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
148 Focal adhesion 💬
2件: PDGFRA, PDGFRB 💬 D08953 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
149 Focal adhesion 💬
3件: PGF, VEGFA, VEGFB 💬 D09574 💬 Aflibercept 2件: 90, 166 💬
150 Focal adhesion 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
151 Focal adhesion 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
152 Focal adhesion 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
153 Focal adhesion 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
154 Focal adhesion 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
155 Focal adhesion 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
156 Focal adhesion 💬
1件: VEGFA 💬 D06409 💬 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 💬
157 Focal adhesion 💬
1件: VEGFA 💬 D05697 💬 Ranibizumab 4件: 34, 166, 227, 301 💬
158 Focal adhesion 💬
1件: VWF 💬 D11160 💬 Caplacizumab 1件: 64 💬
159 Folate biosynthesis 💬
1件: ALPL 💬 D10595 💬 Asfotase alfa 1件: 172 💬
160 Folate biosynthesis 💬
2件: DHFR, DHFR2 💬 D00142 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
161 Folate biosynthesis 💬
2件: DHFR, DHFR2 💬 D02115 💬 Methotrexate 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
162 Folate biosynthesis 💬
1件: PAH 💬 D11077 💬 Pegvaliase 1件: 240 💬
163 Folate biosynthesis 💬
2件: TPH1, TPH2 💬 D09973 💬 Telotristat 1件: 97 💬
164 FoxO signaling pathway 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
165 FoxO signaling pathway 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
166 FoxO signaling pathway 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
167 FoxO signaling pathway 💬
1件: EGFR 💬 D03455 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
168 FoxO signaling pathway 💬
1件: EGFR 💬 D04023 💬 Erlotinib 1件: 94 💬
169 FoxO signaling pathway 💬
1件: EGFR 💬 D07907 💬 Erlotinib 1件: 94 💬
170 FoxO signaling pathway 💬
1件: EGFR 💬 D01977 💬 Gefitinib 1件: 75 💬
171 FoxO signaling pathway 💬
1件: EGFR 💬 D11251 💬 Icotinib 1件: 34 💬
172 FoxO signaling pathway 💬
1件: EGFR 💬 D04024 💬 Lapatinib 3件: 34, 74, 75 💬
173 FoxO signaling pathway 💬
1件: EGFR 💬 D08108 💬 Lapatinib 3件: 34, 74, 75 💬
174 FoxO signaling pathway 💬
1件: EGFR 💬 D11772 💬 Tesevatinib 1件: 67 💬
175 FoxO signaling pathway 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
176 FoxO signaling pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
177 FoxO signaling pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
178 FoxO signaling pathway 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
179 FoxO signaling pathway 💬
2件: IL10, IL6 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
180 FoxO signaling pathway 💬
1件: IL6 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
181 FoxO signaling pathway 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
182 FoxO signaling pathway 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
183 FoxO signaling pathway 💬
1件: INSR 💬 D04539 💬 Insulin detemir 1件: 299 💬
184 FoxO signaling pathway 💬
1件: INSR 💬 D03250 💬 Insulin glargine 1件: 299 💬
185 FoxO signaling pathway 💬
1件: INSR 💬 D00085 💬 Insulin human 2件: 96, 156 💬
186 FoxO signaling pathway 💬
1件: INSR 💬 D03230 💬 Insulin human 2件: 96, 156 💬
187 FoxO signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
188 FoxO signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
189 FoxO signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
190 FoxO signaling pathway 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
191 FoxO signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
192 FoxO signaling pathway 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
193 FoxO signaling pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
194 FoxO signaling pathway 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
195 FoxO signaling pathway 💬
1件: PLK1 💬 D10154 💬 Rigosertib 1件: 36 💬
196 FoxO signaling pathway 💬
2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
197 FoxO signaling pathway 💬
2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
198 FoxO signaling pathway 💬
1件: S1PR1 💬 D11283 💬 Cenerimod 1件: 49 💬
199 FoxO signaling pathway 💬
1件: S1PR1 💬 D10001 💬 Fingolimod 3件: 13, 14, 156 💬
200 FoxO signaling pathway 💬
1件: S1PR1 💬 D11215 💬 Ponesimod 1件: 13 💬
201 FoxO signaling pathway 💬
1件: S1PR1 💬 D11460 💬 Siponimod 2件: 13, 50 💬
202 FoxO signaling pathway 💬
2件: S1PR1, S1PR4 💬 D10930 💬 Etrasimod 3件: 96, 97, 98 💬
203 FoxO signaling pathway 💬
2件: S1PR1, S1PR4 💬 D10968 💬 Ozanimod 3件: 13, 96, 97 💬
204 FoxO signaling pathway 💬
3件: TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab 4件: 51, 85, 222, 274 💬