Target Gene/Pathway PATHWAY / GENE


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Legionellosis 💬
1件: C3 💬 D11613 💬 Pegcetacoplan 3件:  2 , 62, 222 💬
2 Legionellosis 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
3 Legionellosis 💬
2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
4 Legionellosis 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
5 Legionellosis 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
6 Legionellosis 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
7 Legionellosis 💬
3件: IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
8 Legionellosis 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
9 Legionellosis 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
10 Legionellosis 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
11 Legionellosis 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
12 Legionellosis 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
13 Legionellosis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
14 Legionellosis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
15 Legionellosis 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
16 Legionellosis 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
17 Legionellosis 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
18 Legionellosis 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
19 Legionellosis 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
20 Legionellosis 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
21 Legionellosis 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
22 Leishmaniasis 💬
1件: C3 💬 D11613 💬 Pegcetacoplan 3件:  2 , 62, 222 💬
23 Leishmaniasis 💬
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 D04318 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
24 Leishmaniasis 💬
1件: IFNG 💬 D11120 💬 Emapalumab 2件: 49, 107 💬
25 Leishmaniasis 💬
1件: IFNG 💬 D04242 💬 Fontolizumab 1件: 46 💬
26 Leishmaniasis 💬
2件: IFNGR1, IFNGR2 💬 D00747 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
27 Leishmaniasis 💬
4件: IL10, IL1A, IL1B, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
28 Leishmaniasis 💬
2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
29 Leishmaniasis 💬
1件: IL1A 💬 D11253 💬 Bermekimab 1件: 51 💬
30 Leishmaniasis 💬
2件: IL1A, IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
31 Leishmaniasis 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
32 Leishmaniasis 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
33 Leishmaniasis 💬
1件: IL4 💬 D03117 💬 Binetrakin 1件: 46 💬
34 Leishmaniasis 💬
1件: ITGA4 💬 D10540 💬 Abrilumab 2件: 96, 97 💬
35 Leishmaniasis 💬
1件: ITGA4 💬 D06590 💬 Firategrast 1件: 13 💬
36 Leishmaniasis 💬
1件: ITGA4 💬 D06886 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬
37 Leishmaniasis 💬
1件: ITGA4 💬 D08083 💬 Vedolizumab 3件: 94, 96, 97 💬
38 Leishmaniasis 💬
1件: JAK1 💬 D10871 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬
39 Leishmaniasis 💬
1件: JAK1 💬 D10944 💬 Itacitinib 5件: 46, 51, 60, 97, 228 💬
40 Leishmaniasis 💬
1件: JAK1 💬 D10994 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
41 Leishmaniasis 💬
2件: JAK1, JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
42 Leishmaniasis 💬
2件: JAK1, JAK2 💬 D10653 💬 Peficitinib 1件: 46 💬
43 Leishmaniasis 💬
2件: JAK1, JAK2 💬 D09959 💬 Ruxolitinib 1件: 228 💬
44 Leishmaniasis 💬
2件: JAK1, JAK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
45 Leishmaniasis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
46 Leishmaniasis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
47 Leishmaniasis 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
48 Leishmaniasis 💬
1件: PTGS2 💬 D01545 💬 Aceclofenac 1件: 46 💬
49 Leishmaniasis 💬
1件: PTGS2 💬 D00217 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337 💬
50 Leishmaniasis 💬
1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251 💬
51 Leishmaniasis 💬
1件: PTGS2 💬 D00567 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
52 Leishmaniasis 💬
1件: PTGS2 💬 D00903 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
53 Leishmaniasis 💬
1件: PTGS2 💬 D00904 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
54 Leishmaniasis 💬
1件: PTGS2 💬 D07816 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
55 Leishmaniasis 💬
1件: PTGS2 💬 D00130 💬 Diflunisal 1件: 28 💬
56 Leishmaniasis 💬
1件: PTGS2 💬 D00315 💬 Etodolac 1件: 46 💬
57 Leishmaniasis 💬
1件: PTGS2 💬 D03710 💬 Etoricoxib 2件: 46, 271 💬
58 Leishmaniasis 💬
1件: PTGS2 💬 D00330 💬 Flurbiprofen 3件: 13, 21, 46 💬
59 Leishmaniasis 💬
1件: PTGS2 💬 D01475 💬 Flurbiprofen 3件: 13, 21, 46 💬
60 Leishmaniasis 💬
1件: PTGS2 💬 D02290 💬 Flurbiprofen 3件: 13, 21, 46 💬
61 Leishmaniasis 💬
1件: PTGS2 💬 D00126 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
62 Leishmaniasis 💬
1件: PTGS2 💬 D01122 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
63 Leishmaniasis 💬
1件: PTGS2 💬 D04490 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
64 Leishmaniasis 💬
1件: PTGS2 💬 D06606 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
65 Leishmaniasis 💬
1件: PTGS2 💬 D00141 💬 Indomethacin 3件: 225, 271, 298 💬
66 Leishmaniasis 💬
1件: PTGS2 💬 D01565 💬 Indomethacin 3件: 225, 271, 298 💬
67 Leishmaniasis 💬
1件: PTGS2 💬 D02110 💬 Indomethacin 3件: 225, 271, 298 💬
68 Leishmaniasis 💬
1件: PTGS2 💬 D00132 💬 Ketoprofen 1件: 46 💬
69 Leishmaniasis 💬
1件: PTGS2 💬 D00813 💬 Ketorolac 2件: 70, 226 💬
70 Leishmaniasis 💬
1件: PTGS2 💬 D08104 💬 Ketorolac 2件: 70, 226 💬
71 Leishmaniasis 💬
1件: PTGS2 💬 D08149 💬 Loxoprofen 2件: 46, 271 💬
72 Leishmaniasis 💬
1件: PTGS2 💬 D03714 💬 Lumiracoxib 1件: 46 💬
73 Leishmaniasis 💬
1件: PTGS2 💬 D00969 💬 Meloxicam 4件: 46, 49, 271, 296 💬
74 Leishmaniasis 💬
1件: PTGS2 💬 D00118 💬 Naproxen 4件: 13, 46, 107, 271 💬
75 Leishmaniasis 💬
1件: PTGS2 💬 D01049 💬 Nimesulide 1件: 46 💬
76 Leishmaniasis 💬
1件: PTGS2 💬 D03716 💬 Parecoxib 2件: 46, 271 💬
77 Leishmaniasis 💬
1件: PTGS2 💬 D00568 💬 Rofecoxib 1件: 46 💬
78 Leishmaniasis 💬
1件: PTGS2 💬 D00428 💬 Salsalate 1件:  5  💬
79 Leishmaniasis 💬
1件: PTGS2 💬 D00120 💬 Sulindac 1件: 206 💬
80 Leishmaniasis 💬
1件: PTGS2 💬 D01183 💬 Tolfenamic acid 1件:  5  💬
81 Leishmaniasis 💬
1件: PTGS2 💬 D02709 💬 Valdecoxib 1件: 46 💬
82 Leishmaniasis 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
83 Leishmaniasis 💬
3件: TGFB1, TGFB2, TGFB3 💬 D09620 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
84 Leishmaniasis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
85 Leishmaniasis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
86 Leishmaniasis 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
87 Leishmaniasis 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
88 Leishmaniasis 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
89 Leishmaniasis 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
90 Leishmaniasis 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
91 Leishmaniasis 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
92 Leishmaniasis 💬
1件: TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
93 Leishmaniasis 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
94 Leukocyte transendothelial migration 💬
1件: CXCR4 💬 D08971 💬 Plerixafor 6件: 19, 20, 51, 65, 285, 299 💬
95 Leukocyte transendothelial migration 💬
1件: ITGA4 💬 D10540 💬 Abrilumab 2件: 96, 97 💬
96 Leukocyte transendothelial migration 💬
1件: ITGA4 💬 D06590 💬 Firategrast 1件: 13 💬
97 Leukocyte transendothelial migration 💬
1件: ITGA4 💬 D06886 💬 Natalizumab 6件: 13, 15, 25, 46, 63, 96 💬
98 Leukocyte transendothelial migration 💬
1件: ITGA4 💬 D08083 💬 Vedolizumab 3件: 94, 96, 97 💬
99 Leukocyte transendothelial migration 💬
1件: ITGAL 💬 D03959 💬 Efalizumab 9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
100 Leukocyte transendothelial migration 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
101 Leukocyte transendothelial migration 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
102 Leukocyte transendothelial migration 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
103 Leukocyte transendothelial migration 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
104 Leukocyte transendothelial migration 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
105 Leukocyte transendothelial migration 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
106 Lipid and atherosclerosis 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
107 Lipid and atherosclerosis 💬
1件: CASP9 💬 D11195 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬
108 Lipid and atherosclerosis 💬
4件: CCL2, IL1B, IL6, TNF 💬 D01583 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
109 Lipid and atherosclerosis 💬
1件: CD40 💬 D11357 💬 Bleselumab 1件: 222 💬
110 Lipid and atherosclerosis 💬
1件: CD40 💬 D11610 💬 Iscalimab 2件: 49, 53 💬
111 Lipid and atherosclerosis 💬
1件: CD40 💬 D11597 💬 Ravagalimab 2件: 53, 97 💬
112 Lipid and atherosclerosis 💬
1件: CD40LG 💬 D06193 💬 Toralizumab 1件: 63 💬
113 Lipid and atherosclerosis 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09662 💬 Rontalizumab 1件: 49 💬
114 Lipid and atherosclerosis 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 D09668 💬 Sifalimumab 1件: 49 💬
115 Lipid and atherosclerosis 💬
2件: IL12A, IL12B 💬 D09214 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
116 Lipid and atherosclerosis 💬
1件: IL1B 💬 D09315 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
117 Lipid and atherosclerosis 💬
1件: IL1B 💬 D09911 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
118 Lipid and atherosclerosis 💬
1件: IL1B 💬 D06635 💬 Rilonacept 4件: 51, 106, 107, 266 💬
119 Lipid and atherosclerosis 💬
1件: IL6 💬 D09669 💬 Siltuximab 2件: 28, 331 💬
120 Lipid and atherosclerosis 💬
1件: IL6 💬 D10080 💬 Sirukumab 2件: 41, 46 💬
121 Lipid and atherosclerosis 💬
2件: IL6, TNF 💬 D08976 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
122 Lipid and atherosclerosis 💬
1件: JAK2 💬 D10308 💬 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325 💬
123 Lipid and atherosclerosis 💬
1件: JAK2 💬 D10653 💬 Peficitinib 1件: 46 💬
124 Lipid and atherosclerosis 💬
1件: JAK2 💬 D09959 💬 Ruxolitinib 1件: 228 💬
125 Lipid and atherosclerosis 💬
1件: JAK2 💬 D09970 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271 💬
126 Lipid and atherosclerosis 💬
1件: MAP3K5 💬 D10988 💬 Selonsertib 1件: 86 💬
127 Lipid and atherosclerosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D09639 💬 Losmapimod 2件: 113, 222 💬
128 Lipid and atherosclerosis 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 D10959 💬 Neflamapimod 1件:  8  💬
129 Lipid and atherosclerosis 💬
1件: NFE2L2 💬 D10964 💬 Omaveloxolone 1件: 18 💬
130 Lipid and atherosclerosis 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
131 Lipid and atherosclerosis 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
132 Lipid and atherosclerosis 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
133 Lipid and atherosclerosis 💬
1件: PPARG 💬 D11603 💬 Leriglitazone 1件: 20 💬
134 Lipid and atherosclerosis 💬
1件: PPARG 💬 D00945 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
135 Lipid and atherosclerosis 💬
1件: PPARG 💬 D08378 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
136 Lipid and atherosclerosis 💬
1件: PPARG 💬 D00596 💬 Rosiglitazone 5件: 46, 75, 97, 222, 265 💬
137 Lipid and atherosclerosis 💬
1件: PPARG 💬 D08491 💬 Rosiglitazone 5件: 46, 75, 97, 222, 265 💬
138 Lipid and atherosclerosis 💬
1件: PPARG 💬 D11256 💬 Seladelpar 2件: 93, 94 💬
139 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
140 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
141 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
142 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
143 Lipid and atherosclerosis 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
144 Lipid and atherosclerosis 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
145 Lipid and atherosclerosis 💬
1件: ROCK2 💬 D11815 💬 Belumosudil 1件: 51 💬
146 Lipid and atherosclerosis 💬
1件: ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
147 Lipid and atherosclerosis 💬
3件: RXRA, RXRB, RXRG 💬 D02754 💬 Acitretin 1件: 37 💬
148 Lipid and atherosclerosis 💬
3件: RXRA, RXRB, RXRG 💬 D02815 💬 Alitretinoin 1件: 49 💬
149 Lipid and atherosclerosis 💬
3件: RXRA, RXRB, RXRG 💬 D03106 💬 Bexarotene 2件: 13, 75 💬
150 Lipid and atherosclerosis 💬
1件: SRC 💬 D03252 💬 Bosutinib 2件:  2 , 67 💬
151 Lipid and atherosclerosis 💬
1件: SRC 💬 D03658 💬 Dasatinib 2件: 51, 85 💬
152 Lipid and atherosclerosis 💬
1件: SRC 💬 D06414 💬 Dasatinib 2件: 51, 85 💬
153 Lipid and atherosclerosis 💬
1件: SRC 💬 D09664 💬 Saracatinib 3件:  6 , 89, 272 💬
154 Lipid and atherosclerosis 💬
1件: TNF 💬 D02597 💬 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
155 Lipid and atherosclerosis 💬
1件: TNF 💬 D03441 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
156 Lipid and atherosclerosis 💬
1件: TNF 💬 D00742 💬 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
157 Lipid and atherosclerosis 💬
1件: TNF 💬 D04358 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
158 Lipid and atherosclerosis 💬
1件: TNF 💬 D02598 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
159 Lipid and atherosclerosis 💬
1件: TNF 💬 D04687 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
160 Lipid and atherosclerosis 💬
1件: TNF 💬 D09944 💬 Ozoralizumab 1件: 46 💬
161 Lipid and atherosclerosis 💬
1件: TNF 💬 D05393 💬 Pegsunercept 1件: 46 💬
162 Lipid and atherosclerosis 💬
1件: TNF 💬 D00754 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
163 Long-term depression 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
164 Long-term depression 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
165 Long-term depression 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
166 Long-term depression 💬
1件: CRHR1 💬 D03905 💬 Corticorelin 2件: 75, 205 💬
167 Long-term depression 💬
1件: CRHR1 💬 D03592 💬 Corticorelin ovine triflutate 1件: 75 💬
168 Long-term depression 💬
3件: GRIA1, GRIA2, GRIA3 💬 D08964 💬 Perampanel 3件:  2 ,  6 , 144 💬
169 Long-term depression 💬
3件: GRIA1, GRIA2, GRIA3 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
170 Long-term depression 💬
3件: GRIA1, GRIA2, GRIA3 💬 D02696 💬 Talampanel 2件:  2 ,  6  💬
171 Long-term depression 💬
3件: GRIA1, GRIA2, GRIA3 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
172 Long-term depression 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite 1件: 58 💬
173 Long-term depression 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
174 Long-term depression 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
175 Long-term depression 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
176 Long-term depression 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
177 Long-term depression 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
178 Long-term depression 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
179 Long-term depression 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
180 Long-term depression 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
181 Long-term depression 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
182 Long-term potentiation 💬
1件: BRAF 💬 D10064 💬 Dabrafenib 1件: 34 💬
183 Long-term potentiation 💬
2件: BRAF, RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
184 Long-term potentiation 💬
2件: BRAF, RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬
185 Long-term potentiation 💬
1件: CACNA1C 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
186 Long-term potentiation 💬
1件: CACNA1C 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
187 Long-term potentiation 💬
1件: CACNA1C 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
188 Long-term potentiation 💬
1件: CACNA1C 💬 D01173 💬 Cilnidipine 1件: 67 💬
189 Long-term potentiation 💬
1件: CACNA1C 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
190 Long-term potentiation 💬
1件: CACNA1C 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
191 Long-term potentiation 💬
1件: CACNA1C 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
192 Long-term potentiation 💬
1件: CACNA1C 💬 D00349 💬 Isradipine 1件:  6  💬
193 Long-term potentiation 💬
1件: CACNA1C 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
194 Long-term potentiation 💬
1件: CACNA1C 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
195 Long-term potentiation 💬
1件: CACNA1C 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
196 Long-term potentiation 💬
1件: CACNA1C 💬 D01908 💬 Nilvadipine 1件: 90 💬
197 Long-term potentiation 💬
1件: CACNA1C 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
198 Long-term potentiation 💬
1件: CACNA1C 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
199 Long-term potentiation 💬
1件: CACNA1C 💬 D08441 💬 Propiverine 1件: 226 💬
200 Long-term potentiation 💬
1件: CACNA1C 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
201 Long-term potentiation 💬
1件: CACNA1C 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
202 Long-term potentiation 💬
3件: CACNA1C, GRIA1, GRIA2 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
203 Long-term potentiation 💬
2件: GRIA1, GRIA2 💬 D08964 💬 Perampanel 3件:  2 ,  6 , 144 💬
204 Long-term potentiation 💬
2件: GRIA1, GRIA2 💬 D02696 💬 Talampanel 2件:  2 ,  6  💬
205 Long-term potentiation 💬
7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
206 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate 2件:  6 , 206 💬
207 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate 2件:  6 , 206 💬
208 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
209 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
210 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
211 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
212 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
213 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
214 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
215 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
216 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine 1件:  8  💬
217 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
218 Long-term potentiation 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
219 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
220 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
221 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
222 Long-term potentiation 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
223 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00184 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
224 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D05480 💬 Pimecrolimus 1件: 160 💬
225 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D00107 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
226 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D08556 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
227 Long-term potentiation 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 D09033 💬 Voclosporin 1件: 222 💬
228 Longevity regulating pathway 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
229 Longevity regulating pathway 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
230 Longevity regulating pathway 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
231 Longevity regulating pathway 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
232 Longevity regulating pathway 💬
1件: INSR 💬 D04539 💬 Insulin detemir 1件: 299 💬
233 Longevity regulating pathway 💬
1件: INSR 💬 D03250 💬 Insulin glargine 1件: 299 💬
234 Longevity regulating pathway 💬
1件: INSR 💬 D00085 💬 Insulin human 2件: 96, 156 💬
235 Longevity regulating pathway 💬
1件: INSR 💬 D03230 💬 Insulin human 2件: 96, 156 💬
236 Longevity regulating pathway 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
237 Longevity regulating pathway 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
238 Longevity regulating pathway 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
239 Longevity regulating pathway 💬
1件: NFKB1 💬 D01146 💬 Iguratimod 4件: 46, 51, 53, 271 💬
240 Longevity regulating pathway 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
241 Longevity regulating pathway 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
242 Longevity regulating pathway 💬
1件: PPARG 💬 D11603 💬 Leriglitazone 1件: 20 💬
243 Longevity regulating pathway 💬
1件: PPARG 💬 D00945 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
244 Longevity regulating pathway 💬
1件: PPARG 💬 D08378 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
245 Longevity regulating pathway 💬
1件: PPARG 💬 D00596 💬 Rosiglitazone 5件: 46, 75, 97, 222, 265 💬
246 Longevity regulating pathway 💬
1件: PPARG 💬 D08491 💬 Rosiglitazone 5件: 46, 75, 97, 222, 265 💬
247 Longevity regulating pathway 💬
1件: PPARG 💬 D11256 💬 Seladelpar 2件: 93, 94 💬
248 Longevity regulating pathway 💬
2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
249 Longevity regulating pathway 💬
2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
250 Longevity regulating pathway 💬
1件: RELA 💬 D12181 💬 Edasalonexent 1件: 113 💬
251 Longevity regulating pathway - multiple species 💬
2件: HDAC1, HDAC2 💬 D06320 💬 Vorinostat 3件: 19, 75, 96 💬
252 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
253 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
254 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
255 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
256 Longevity regulating pathway - multiple species 💬
1件: INSR 💬 D04539 💬 Insulin detemir 1件: 299 💬
257 Longevity regulating pathway - multiple species 💬
1件: INSR 💬 D03250 💬 Insulin glargine 1件: 299 💬
258 Longevity regulating pathway - multiple species 💬
1件: INSR 💬 D00085 💬 Insulin human 2件: 96, 156 💬
259 Longevity regulating pathway - multiple species 💬
1件: INSR 💬 D03230 💬 Insulin human 2件: 96, 156 💬
260 Longevity regulating pathway - multiple species 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
261 Longevity regulating pathway - multiple species 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
262 Longevity regulating pathway - multiple species 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
263 Longevity regulating pathway - multiple species 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
264 Longevity regulating pathway - multiple species 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
265 Longevity regulating pathway - multiple species 💬
2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
266 Longevity regulating pathway - multiple species 💬
2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
267 Longevity regulating pathway - multiple species 💬
1件: SOD1 💬 D11811 💬 Tofersen 1件:  2  💬
268 Lysosome 💬
1件: ARSB 💬 D06565 💬 Galsulfase 1件: 19 💬
269 Lysosome 💬
1件: CTSC 💬 D12120 💬 Brensocatib 1件: 299 💬
270 Lysosome 💬
1件: GAA 💬 D00216 💬 Acarbose 1件: 298 💬
271 Lysosome 💬
1件: GAA 💬 D03207 💬 Alglucosidase alfa 1件: 256 💬
272 Lysosome 💬
1件: GAA 💬 D11744 💬 Avalglucosidase alfa 1件: 256 💬
273 Lysosome 💬
1件: GAA 💬 D11798 💬 Cipaglucosidase alfa 1件: 256 💬
274 Lysosome 💬
1件: GAA 💬 D09605 💬 Duvoglustat 1件: 256 💬
275 Lysosome 💬
1件: GALNS 💬 D10333 💬 Elosulfase alfa 1件: 19 💬
276 Lysosome 💬
1件: GBA 💬 D02810 💬 Alglucerase 1件: 19 💬
277 Lysosome 💬
1件: GBA 💬 D03020 💬 Imiglucerase 1件: 19 💬
278 Lysosome 💬
1件: GBA 💬 D09675 💬 Taliglucerase alfa 1件: 19 💬
279 Lysosome 💬
1件: GBA 💬 D09029 💬 Velaglucerase alfa 1件: 19 💬
280 Lysosome 💬
1件: GLA 💬 D02784 💬 Agalsidase alfa 1件: 19 💬
281 Lysosome 💬
1件: GLA 💬 D03228 💬 Agalsidase beta 1件: 19 💬
282 Lysosome 💬
1件: GUSB 💬 D11004 💬 Vestronidase alfa 1件: 19 💬
283 Lysosome 💬
1件: IDS 💬 D04499 💬 Idursulfase 1件: 19 💬
284 Lysosome 💬
1件: IDS 💬 D11025 💬 Idursulfase beta 1件: 19 💬
285 Lysosome 💬
1件: IDS 💬 D11812 💬 Pabinafusp alfa 1件: 19 💬
286 Lysosome 💬
1件: IDUA 💬 D04670 💬 Laronidase 2件: 19, 256 💬
287 Lysosome 💬
1件: LIPA 💬 D10377 💬 Sebelipase alfa 1件: 19 💬
288 Lysosome 💬
1件: MAN2B1 💬 D11024 💬 Velmanase alfa 1件: 19 💬
289 Lysosome 💬
1件: SMPD1 💬 D10820 💬 Olipudase alfa 1件: 19 💬
290 Lysosome 💬
1件: TPP1 💬 D10813 💬 Cerliponase alfa 1件: 19 💬