Disease The intractable diseases designated by MHLW, Japan

Diseases : 338 - Clinical trials : 34,520 / Drugs : 19,957 - ( DrugBank : 2,195 ) / Drug target genes : 613 - Drug target pathways : 297

1050100ALL diseases per page:

Showing 1 to 10 of 22 diseases

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ID	Disease name [Group]	Clinical trial Phase 1 / 2 / 3 / 4	Drug [ DrugBank ]	Target gene Target pathway	Domestic patients Med expenses recipients (FY2022)
91	Budd-Chiari syndrome [Gast] 💬 "BCS", "Primary Budd-Chiari syndrome", "Secondary Budd-Chiari syndrome"	4 trials    | 0 / 0 / 0 / 1 💬	5 drugs   [ 4 drugs ]	4 genes   14 pathways	211 patients Age distribution💬   91. Budd-Chiari syndrome × Age Num 0-9 - 10-19 1 20-29 15 30-39 30 40-49 53 50-59 50 60-69 28 70-74 17 75- 17
92	Idiopathic portal hypertension [Gast] 💬 "Banti syndrome"	-	-	-	313 patients Age distribution💬   92. Idiopathic portal hypertension × Age Num 0-9 - 10-19 2 20-29 20 30-39 30 40-49 50 50-59 70 60-69 61 70-74 45 75- 35
93	Primary biliary cholangitis [Gast] 💬 "Primary biliary cirrhosis", "PBC", "Asymptomatic primary biliary cholangitis", "Asymptomatic rimary biliary cirrhosis", "aPBC", "Symptomatic primary biliary cholangitis", "Symptomatic primary biliary cirrhosis", "sPBC"  "Primary biliary cirrhosis", "PBC", "Asymptomatic primary biliary cholangitis", "Asymptomatic rimary ...	298 trials    | 148 / 136 / 110 / 64 💬	252 drugs   [ 59 drugs ]	35 genes   115 pathways	16,625 patients Age distribution💬   93. Primary biliary cholangitis × Age Num 0-9 - 10-19 - 20-29 16 30-39 155 40-49 922 50-59 2,646 60-69 4,549 70-74 3,197 75- 5,140
94	Primary sclerosing cholangitis [Gast] 💬 "PSC", "Intrahepatic primary sclerosing cholangitis", "Intrahepatic PSC", "Extrahepatic primary sclerosing cholangitis", "Extrahepatic PSC", "Intrahepatic and extrahepatic primary sclerosing cholangitis", "Intrahepatic and extrahepatic PSC"  "PSC", "Intrahepatic primary sclerosing cholangitis", "Intrahepatic PSC", "Extrahepatic primary scle ...	148 trials    | 68 / 66 / 51 / 10 💬	118 drugs   [ 39 drugs ]	18 genes   141 pathways	1,106 patients Age distribution💬   94. Primary sclerosing cholangitis × Age Num 0-9 - 10-19 8 20-29 158 30-39 192 40-49 191 50-59 169 60-69 138 70-74 97 75- 153
95	Autoimmune hepatitis [Gast] 💬	52 trials    | 11 / 25 / 11 / 11 💬	68 drugs   [ 27 drugs ]	18 genes   111 pathways	7,081 patients Age distribution💬   95. Autoimmune hepatitis × Age Num 0-9 1 10-19 11 20-29 93 30-39 187 40-49 572 50-59 1,344 60-69 1,848 70-74 1,300 75- 1,725
96	Crohn disease [Gast] 💬 "Terminal ileitis"	2,442 trials    | 898 / 766 / 1004 / 332 💬	1,278 drugs   [ 248 drugs ]	142 genes   209 pathways	50,184 patients Age distribution💬   96. Crohn disease × Age Num 0-9 4 10-19 613 20-29 8,948 30-39 11,054 40-49 12,404 50-59 9,818 60-69 4,369 70-74 1,405 75- 1,569
97	Ulcerative colitis [Gast] 💬	2,630 trials    | 943 / 957 / 1089 / 298 💬	1,459 drugs   [ 265 drugs ]	144 genes   202 pathways	141,387 patients Age distribution💬   97. Ulcerative colitis × Age Num 0-9 4 10-19 1,150 20-29 15,089 30-39 21,816 40-49 30,396 50-59 30,318 60-69 21,285 70-74 9,610 75- 11,719
98	Eosinophilic gastrointestinal disease [Gast] 💬 "Eosinophilic gastroenteritis", "Eosinophilic esophagitis", "Eosinophilic colitis", "Eosinophilic gastro-intestinal disorder", "EGID", "Neonatal food-protein induced enterocolitis", "Neonatal Food-protein induced enterocolitis syndrome", "N-FPIES"  "Eosinophilic gastroenteritis", "Eosinophilic esophagitis", "Eosinophilic colitis", "Eosinophilic ga ...	172 trials    | 48 / 64 / 90 / 13 💬	149 drugs   [ 39 drugs ]	38 genes   135 pathways	1,280 patients Age distribution💬   98. Eosinophilic gastrointestinal disease × Age Num 0-9 11 10-19 86 20-29 118 30-39 185 40-49 269 50-59 304 60-69 169 70-74 69 75- 69
99	Chronic intestinal pseudo-obstruction [Gast] 💬 "Chronic idiopathic pseudo-bowel obstruction", "Chronic Idiopathic Intestinal Pseudo-Obstruction", "CIIP"  "Chronic idiopathic pseudo-bowel obstruction", "Chronic Idiopathic Intestinal Pseudo-Obstruction", " ...	4 trials    | 0 / 4 / 0 / 0 💬	9 drugs   [ 2 drugs ]	1 gene   4 pathways	182 patients Age distribution💬   99. Chronic intestinal pseudo-obstruction × Age Num 0-9 - 10-19 1 20-29 24 30-39 25 40-49 32 50-59 48 60-69 28 70-74 14 75- 10
100	Megacystis microcolon intestinal hypoperistalsis syndrome [Gast] 💬 "MMIHS", "Huge bladder short and small colon intestinal peristalsis deficiency"	-	-	-	2 patients Age distribution💬   100. Megacystis microcolon intestinal hypoperistalsis syndrome × Age Num 0-9 - 10-19 - 20-29 1 30-39 1 40-49 - 50-59 - 60-69 - 70-74 - 75- -

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