DDrare

Information about drug development for rare and intractable diseases

What is DDrare?

DDrare is a database that provides information on drugs in clinical trials, and
drug target genes and pathways, related to the intractable diseases (mostly rare diseases)
designated by the Ministry of Health, Labour and Welfare (MHLW), Japan.

DDrare : Database of Drug Development for Rare Diseases

Data version: Mar2022

News

Mar 31, 2022 Data ver. Mar2022. Updated to the 338 designated intractable diseases in Japan, with new site design and interfaces. Previous versions are: Mar2021, Nov2019
Mar 8, 2022 The number of "Medical expenses recipients" was updated to FY2020 data (333 diseases) in Disease.
Oct 4, 2021 Links to related pediatric diseases were added in Disease.
Sep 28, 2021 DDrare ~ Database of developing drugs, target genes and pathways for rare diseases ~ is added to References.
Jun 11, 2021 Our paper "Drug Target Gene-based Analyses of Drug Repositionability in Rare and Intractable Diseases." was published.
Mar 30, 2021 Data ver. Mar2021. Database system improvement (sort, filter, etc.) and data updates (new info. of age class of patients, etc.) were conducted.
Sep 25, 2020 DDrare - Database of developing drugs, target genes and pathways for rare diseases - is added to References.
Sep 25, 2020 Sitemaps for the three entrances (Disease, Drug and Target Gene/Pathway) are equipped.
Sep 9, 2020 A few drug names were corrected (12,172 drugs -> 12,170 drugs).
Jun 29, 2020 Drugs and target genes shown in Target Gene/Pathway for each disease are now limited to those for the diesase (i.e. Drugs and target genes only for other diseases in a pathway are not shown.). (e.g. Spinal and bulbar muscular atrophy)
Jun 22, 2020 English version has opened.
Mar 30, 2018 Newly open to public.

Features

Information of Drug Development extracted from Clinical Trials

Drugs are extracted from clinical trials for the intractable diseases (mostly rare diseases) designated by MHLW, Japan.

Clinical Trials for Rare Diseases in the World’s Four Major Registries

Comprehensive information is available from the four major clinical trial registries of Japan, US, EU and China.

Cross-Reference information for Drug Development

Among Diseases, Drugs, and Target Genes/Pathways, cross-reference is available for target discovery in drug development.

Statistics

Diseases

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Clinical Trials

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Drugs

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Target Genes

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Target Pathways

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Disclaimer

The information on this website is provided for research purposes only and does not replace the advice or consultation of a doctor. In principle, all rights relating to the information on this website belong to National Institutes of Biomedical Innovation, Health and Nutrition. Please contact us in advance if you would like to use the information on this website. Information on this website is subject to change without notice. In any case, we will not be liable for any damages arising from the use of the information on this website.