Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept [2] ABATACEPT; ORENCIA[1] Abatacept 💬[2] CD80,
CD86 💬		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Ademetionine [2] SAM-e; SAMe[1] Ademetionine 💬--[2] 6, 93 💬
3 Alkaline Phosphatase [1] Alkaline Phosphatase---[4] 46, 93, 97, 172 💬
4 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Lipitor[1] Atorvastatin 💬[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
5 Azathioprine [3] Azathioprine; Azatioprina; Imuran[1] Azathioprine 💬--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
6 Baricitinib [2] BARICITINIB; Olumiant[1] Baricitinib 💬[2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
7 Bezafibrate [1] BEZAFIBRATE[1] Bezafibrate 💬[1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[7] 20, 93, 94, 160, 296, 316, 324 💬
8 Budesonide [4] Budesonide; Entocort; Jorveza; Symbicort[1] Budesonide 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
9 Calcium [2] Calcio; Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
10 Choline [1] Choline[1] Choline 💬--[4] 93, 171, 193, 299 💬
11 Cilofexor [1] Cilofexor---[2] 93, 94 💬
12 Colchicine [2] COLCHICINA; Colchicine[1] Colchicine 💬[9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[7] 2, 42, 46, 56, 93, 210, 266 💬
13 Cyclophosphamide [6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan[2] Cyclophosphamide ,
Cyclophosphamide 💬		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
14 Cyclosporine [10] CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; RESTASIS[1] Cyclosporine 💬[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
15 Denosumab [3] DENOSUMAB; Prolia; XGEVA[1] Denosumab 💬[1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[8] 46, 50, 70, 93, 95, 96, 274, 299 💬
16 Elafibranor [1] Elafibranor[1] Elafibranor 💬[1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[2] 93, 94 💬
17 Emtricitabine [2] Emtricitabine; TRUVADA[1] Emtricitabine 💬--[4] 25, 93, 265, 325 💬
18 Ezetimibe [2] EZETIMIBE; Ezetrol[1] Ezetimibe 💬[1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260 💬
19 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬[1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
20 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
21 GSK-2330672 [0] ---[1] 93 💬
22 Hesperidin [1] Hesperidin[1] Hesperidin 💬--[2] 46, 93 💬
23 Lopinavir [2] Kaletra; Lopinavir[1] Lopinavir 💬--[2] 93, 265 💬
24 Magnesium [1] Magnesium---[19] 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298 💬
25 Methionine [3] Butanoic acid; L-methionine; Methionine[1] Methionine 💬--[6] 34, 84, 93, 229, 298, 300 💬
26 Methotrexate [6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate[1] Methotrexate 💬[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
27 Methylprednisolone [4] Medrol; Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[1] Methylprednisolone 💬[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
28 Minodronic acid [2] Minodronate; Minodronic acid---[4] 6, 46, 93, 95 💬
29 Modafinil [2] MODAFINIL; Provigil[1] Modafinil 💬--[5] 6, 13, 49, 93, 113 💬
30 Moexipril [1] Moexipril[1] Moexipril 💬[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 93 💬
31 Mycophenolate mofetil [3] CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA[1] Mycophenolate mofetil 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
32 Mycophenolic acid [5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic Acid; Myfortic[1] Mycophenolic acid 💬[2] IMPDH1,
IMPDH2 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
33 norUrsodeoxycholic acid [2] Norucholic acid; NorUrsodeoxycholic Acid---[2] 93, 94 💬
34 Obeticholic acid [4] 6-ECDCA; 6-ethylchenodeoxycholic acid; Obeticholic Acid; Ocaliva[1] Obeticholic acid 💬[1] NR1H4 💬[1] Bile secretion 💬[3] 93, 265, 296 💬
35 Pemafibrate [1] Pemafibrate[1] Pemafibrate 💬[1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[1] 93 💬
36 Pentoxifylline [1] Pentoxifylline[1] Pentoxifylline 💬--[12] 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
37 Phenylbutyric acid [4] 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338 💬
38 Potassium [1] Potassium[1] Potassium 💬--[13] 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
39 Pyridoxine [2] Pyridoxine; Vitamin B6[1] Pyridoxine 💬--[5] 6, 93, 145, 206, 320 💬
40 Raltegravir [2] ISENTRESS; Raltegravir[1] Raltegravir 💬--[4] 13, 26, 93, 265 💬
41 Rifampicin [2] Rifampicin; Rifampin[1] Rifampin 💬--[9] 6, 13, 17, 46, 84, 86, 93, 299, 338 💬
42 Rifaximin [3] Rifaximin; RIFAXIMINA; Xifaxan[1] Rifaximin 💬--[9] 6, 65, 93, 94, 96, 97, 99, 296, 299 💬
43 Risedronic acid [3] Risedronate; RISEDRONATE SODIUM; Risedronic acid[1] Risedronic acid 💬[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
44 Rituximab [6] MabThera; Rituxan; RITUXIMAB; Rixathon; Ruxience; Truxima[1] Rituximab 💬[1] MS4A1 💬[1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
45 Saroglitazar [1] Saroglitazar---[1] 93 💬
46 Seladelpar [1] SELADELPAR[1] Seladelpar 💬[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[2] 93, 94 💬
47 Setanaxib [1] SETANAXIB---[1] 93 💬
48 Tauroursodeoxycholic acid [4] Tauroursodeoxycholic acid; Taurursodiol; TUDCA; Ursodoxicoltaurine[1] Taurursodiol 💬--[3] 2, 93, 299 💬
49 Tenofovir [1] Tenofovir[1] Tenofovir 💬--[6] 2, 13, 25, 93, 265, 325 💬
50 Tenofovir disoproxil [4] Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA---[2] 93, 265 💬
51 Tetrathiomolybdate [1] Tetrathiomolybdate---[3] 85, 93, 171 💬
52 Thiamine [2] Thiamine; Vitamin B1[1] Thiamine 💬--[4] 8, 93, 145, 265 💬
53 Tigecycline [1] Tigecycline[1] Tigecycline 💬--[1] 93 💬
54 Tropifexor [1] Tropifexor[1] Tropifexor 💬[1] NR1H4 💬[1] Bile secretion 💬[1] 93 💬
55 Ursodeoxycholic acid [4] UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk[1] Ursodiol 💬[1] NR1H4 💬[1] Bile secretion 💬[14] 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
56 Ustekinumab [2] STELARA; Ustekinumab[1] Ustekinumab 💬[3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[16] 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
57 Vitamin D [3] Calciferol; Cod liver oil; Vitamin D---[20] 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299 💬
58 Volixibat [1] VOLIXIBAT[1] Volixibat 💬--[2] 93, 94 💬
59 Zoledronic acid [4] ACLASTA; Zoledronate; Zoledronic acid; Zometa[2] Zoledronic acid ,
Zoledronic acid 💬		[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬