Drug Description in Trials / DrugBank / KEGG DRUG
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Showing 1 to 5 of 5 drugs
| No. | DrugBank | Drug (Description in trials) | KEGG DRUG | KEGG GENES | KEGG PATHWAY | Disease ID | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Metformin | [5] Metformin Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine | [1] Metformin
Metformin
💬1. Metformin
| [2] PRKAA1 PRKAA1,PRKAA2 💬 | [20] AMPK signaling pathway AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬 [20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signal ... | [25] 2 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 [25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 28 ... 1. Metformin
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| 2 |
Pioglitazone
(Pioglitazone and metformin) | [1] Pioglitazone Pioglitazone | [1] Pioglitazone
Pioglitazone
💬2. Pioglitazone
| [1] PPARG PPARG 💬2. Pioglitazone
| [11] AMPK signaling pathway AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pat ... | [17] 2 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬2. Pioglitazone
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| 3 |
Repaglinide
(Repaglinide and Metformin Hydrochloride) | [1] Repaglinide Repaglinide | [1] Repaglinide
Repaglinide
💬3. Repaglinide
| [2] ABCC8 ABCC8,KCNJ11 💬 | [4] ABC transporters ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬 | [4] 6 6, 21, 46, 299 💬
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| 4 |
Rosiglitazone
(PMS-rosiglitazone-metformin) | [2] Rosiglitazone Rosiglitazone; Rosiglitazone maleate | [1] Rosiglitazone
Rosiglitazone
💬4. Rosiglitazone
| [1] PPARG PPARG 💬4. Rosiglitazone
| [11] AMPK signaling pathway AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pat ... | [5] 46 46, 75, 97, 222, 265 💬
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| 5 |
Sitagliptin
(Apo-sitagliptin/metformin XR) | [1] Sitagliptin Sitagliptin | [1] Sitagliptin
Sitagliptin
💬5. Sitagliptin
| [1] DPP4 DPP4 💬5. Sitagliptin
| [1] Protein digestion and absorption Protein digestion and absorption 💬 | [4] 6 6, 75, 233, 299 💬
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