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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
MAPK14
💬
1. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
[62]
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[62]
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Losmapimod
Losmapimod
💬
1. MAPK14
×
Name
Other Names
Losmapimod
Losmapimod (USAN/INN)
Losmapimod
[2]
113
113
,
222
💬
1. MAPK14
×
Disease ID
Name
113
Muscular dystrophy
222
Primary nephrotic syndrome
2
MAPK14
💬
2. MAPK14
×
Name
Full Name
MAPK14
mitogen-activated protein kinase 14
[62]
Endocrine resistance
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
Sphingolipid signaling pathway
,
Oocyte meiosis
,
Cellular senescence
,
Adrenergic signaling in cardiomyocytes
,
VEGF signaling pathway
,
Osteoclast differentiation
,
Signaling pathways regulating pluripotency of stem cells
,
Platelet activation
,
Neutrophil extracellular trap formation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
TNF signaling pathway
,
Leukocyte transendothelial migration
,
Thermogenesis
,
Neurotrophin signaling pathway
,
Retrograde endocannabinoid signaling
,
Dopaminergic synapse
,
Inflammatory mediator regulation of TRP channels
,
GnRH signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Relaxin signaling pathway
,
Non-alcoholic fatty liver disease
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Alcoholic liver disease
,
Amyotrophic lateral sclerosis
,
Prion disease
,
Pathways of neurodegeneration - multiple diseases
,
Epithelial cell signaling in Helicobacter pylori infection
,
Pathogenic Escherichia coli infection
,
Shigellosis
,
Salmonella infection
,
Pertussis
,
Yersinia infection
,
Leishmaniasis
,
Chagas disease
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Human cytomegalovirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Epstein-Barr virus infection
,
Human immunodeficiency virus 1 infection
,
Coronavirus disease - COVID-19
,
Proteoglycans in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Diabetic cardiomyopathy
,
Lipid and atherosclerosis
,
Fluid shear stress and atherosclerosis
[62]
Endocrine resistance
,
MAPK signaling pathway
,
Rap1 signaling pathway
,
FoxO signaling pathway
,
S
...
Neflamapimod
Neflamapimod
💬
2. MAPK14
×
Name
Other Names
Neflamapimod
Neflamapimod (USAN)
Neflamapimod
[1]
8
8
💬
2. MAPK14
×
Disease ID
Name
8
Huntington disease
3
CSF1R
💬
3. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Sunitinib
Sunitinib
💬
3. CSF1R
×
Name
Other Names
Sunitinib
Sunitinib (INN)
Sunitinib
[2]
28
28
,
34
💬
3. CSF1R
×
Disease ID
Name
28
Systemic amyloidosis
34
Neurofibromatosis
4
CSF1R
💬
4. CSF1R
×
Name
Full Name
CSF1R
colony stimulating factor 1 receptor
[11]
MAPK signaling pathway
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
PI3K-Akt signaling pathway
,
Osteoclast differentiation
,
Hematopoietic cell lineage
,
Pathways in cancer
,
Transcriptional misregulation in cancer
,
Acute myeloid leukemia
[11]
MAPK signaling pathway
,
Ras signaling pathway
,
Rap1 signaling pathway
,
Cytokine-cytokine recept
...
Pexidartinib
Pexidartinib
💬
4. CSF1R
×
Name
Other Names
Pexidartinib
Pexidartinib (USAN/INN)
Pexidartinib
[1]
34
34
💬
4. CSF1R
×
Disease ID
Name
34
Neurofibromatosis
5
LILRA4
💬
5. LILRA4
×
Name
Full Name
LILRA4
leukocyte immunoglobulin like receptor A4
[2]
Osteoclast differentiation
Osteoclast differentiation
,
B cell receptor signaling pathway
Daxdilimab
Daxdilimab
💬
5. LILRA4
×
Name
Other Names
Daxdilimab
Daxdilimab (USAN)
Daxdilimab
[2]
49
49
,
50
💬
5. LILRA4
×
Disease ID
Name
49
Systemic lupus erythematosus
50
Dermatomyositis
6
FYN
💬
6. FYN
×
Name
Full Name
FYN
FYN proto-oncogene, Src family tyrosine kinase
[14]
Sphingolipid signaling pathway
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast differentiation
,
Focal adhesion
,
Adherens junction
,
Platelet activation
,
Natural killer cell mediated cytotoxicity
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Cholinergic synapse
,
Prion disease
,
Pathogenic Escherichia coli infection
,
Viral myocarditis
[14]
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast di
...
Dasatinib
Dasatinib
💬
6. FYN
×
Name
Other Names
Dasatinib
Dasatinib (JAN/INN)
Dasatinib
[2]
51
51
,
85
💬
6. FYN
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
7
FYN
💬
7. FYN
×
Name
Full Name
FYN
FYN proto-oncogene, Src family tyrosine kinase
[14]
Sphingolipid signaling pathway
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast differentiation
,
Focal adhesion
,
Adherens junction
,
Platelet activation
,
Natural killer cell mediated cytotoxicity
,
T cell receptor signaling pathway
,
Fc epsilon RI signaling pathway
,
Cholinergic synapse
,
Prion disease
,
Pathogenic Escherichia coli infection
,
Viral myocarditis
[14]
Sphingolipid signaling pathway
,
Phospholipase D signaling pathway
,
Axon guidance
,
Osteoclast di
...
Dasatinib
Dasatinib
💬
7. FYN
×
Name
Other Names
Dasatinib
Dasatinib (USAN)
Dasatinib hydrate (JAN)
Sprycel (TN)
Dasatinib
[2]
51
51
,
85
💬
7. FYN
×
Disease ID
Name
51
Scleroderma
85
Idiopathic interstitial pneumonia
8
IFNAR1
💬
8. IFNAR1
×
Name
Full Name
IFNAR1
interferon alpha and beta receptor subunit 1
[18]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
[18]
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast dif
...
Interferon alfa-2a
Interferon alfa-2a
💬
8. IFNAR1
×
Name
Other Names
Interferon alfa-2a
Interferon alfa-2a (USAN/INN)
Interferon alfa-2a (genetical recombination) (JAN)
Roferon A (TN)
Interferon alfa-2a
[1]
56
56
💬
8. IFNAR1
×
Disease ID
Name
56
Behcet disease
9
IFNAR1
💬
9. IFNAR1
×
Name
Full Name
IFNAR1
interferon alpha and beta receptor subunit 1
[18]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
[18]
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast dif
...
Interferon beta-1b
Interferon beta-1b
💬
9. IFNAR1
×
Name
Other Names
Interferon beta-1b
Interferon beta-1b (USAN/INN)
Interferon beta-1b (genetical recombination) (JAN)
Betaseron (TN)
Extavia (TN)
Interferon beta-1b
[1]
13
13
💬
9. IFNAR1
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
10
IFNAR1
💬
10. IFNAR1
×
Name
Full Name
IFNAR1
interferon alpha and beta receptor subunit 1
[18]
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
Toll-like receptor signaling pathway
,
NOD-like receptor signaling pathway
,
JAK-STAT signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Hepatitis C
,
Hepatitis B
,
Measles
,
Influenza A
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Epstein-Barr virus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
[18]
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Osteoclast dif
...
Interferon alfa-2b
Interferon alfa-2b
💬
10. IFNAR1
×
Name
Other Names
Interferon alfa-2b
Interferon alfa-2b (USAN)
Interferon alfa-2b (genetical recombination) (JAN)
Intron A (TN)
Interferon alfa-2b
[2]
25
25
,
34
💬
10. IFNAR1
×
Disease ID
Name
25
Progressive multifocal leukoencephalopathy
34
Neurofibromatosis