Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

Noradrenaline 💬

[2] 22, 296 💬

2

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

Epinephrine 💬

Name	Other Names
Epinephrine	Epinephrine (USP/INN) Adrenaline (JP18) Adrenalin (TN) Auvi-q (TN) Epipen (TN) ADRENALIN(R) CERTA DOSE EPINEPHRINE CONVENIENCE KIT EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL EPINEPHRINE PROFESSIONAL EMS EPINEPHRINESNAP-EMS EPINEPHRINESNAP-V SYMJEPI

[3] 46, 70, 96 💬

3

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

[1] 11 💬

4

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

Carvedilol 💬

[4] 57, 86, 113, 210 💬

5

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

[2] 157, 227 💬

6

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

[1] 6 💬

7

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

[5] 5, 6, 17, 169, 170 💬

8

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬

Disease ID	Name
3	Spinal muscular atrophy
11	Myasthenia gravis
12	Congenital myasthenic syndrome
13	Multiple sclerosis/Neuromyelitis optica
49	Systemic lupus erythematosus
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
111	Congenital myopathy
113	Muscular dystrophy
256	Muscle glycogenosis
299	Cystic fibrosis

9

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

Tulobuterol 💬

[1] 6 💬

10

[9] Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligan ...

Dipivefrin 💬

[1] 6 💬

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