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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
PTGS2
💬
1.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Aspirin
Aspirin
💬
1.
PTGS2
×
Name
Other Names
Aspirin
Aspirin (JP18/USP)
Aspalon (JAN)
Acetylsalicylic acid
Easprin (TN)
Durlaza (TN)
Acetylsalicylic acid
[14]
13
13
,
22
,
46
,
49
,
51
,
58
,
64
,
86
,
97
,
113
,
158
,
210
,
231
,
251
💬
1.
PTGS2
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
22
Moyamoya disease
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
58
Hypertrophic cardiomyopathy
64
Thrombotic thrombocytopenic purpura
86
Pulmonary arterial hypertension
97
Ulcerative colitis
113
Muscular dystrophy
158
Tuberous sclerosis
210
Single Ventricle
231
Alpha-1-antitrypsin deficiency
251
Urea cycle disorder
2
PTGS2
💬
2.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Naproxen
Naproxen
💬
2.
PTGS2
×
Name
Other Names
Naproxen
Naproxen (JP18/USP/INN)
Naprosyn (TN)
EC-NAPROXEN
NAPROXEN SODIUM
NAPROXEN ORAL SUSPENSION
Naproxen
[4]
13
13
,
46
,
107
,
271
💬
2.
PTGS2
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
46
Malignant rheumatoid arthritis
107
Juvenile idiopathic arthritis
271
Ankylosing spondylitis
3
PTGS2
💬
3.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Sulindac
Sulindac
💬
3.
PTGS2
×
Name
Other Names
Sulindac
Sulindac (JP18/USP/INN)
Clinoril (TN)
Sulindac
[1]
206
206
💬
3.
PTGS2
×
Disease ID
Name
206
Fragile X syndrome
4
PTGS2
💬
4.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Ibuprofen
Ibuprofen
💬
4.
PTGS2
×
Name
Other Names
Ibuprofen
Ibuprofen (JP18/USP/INN)
Advil (TN)
Motrin (TN)
CALDOLOR
IBU
Ibuprofen
[7]
13
13
,
46
,
65
,
107
,
113
,
271
,
299
💬
4.
PTGS2
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
46
Malignant rheumatoid arthritis
65
Primary immunodeficiency
107
Juvenile idiopathic arthritis
113
Muscular dystrophy
271
Ankylosing spondylitis
299
Cystic fibrosis
5
PTGS2
💬
5.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Diflunisal
Diflunisal
💬
5.
PTGS2
×
Name
Other Names
Diflunisal
Diflunisal (JAN/USP/INN)
Dolobid (TN)
Diflunisal
[1]
28
28
💬
5.
PTGS2
×
Disease ID
Name
28
Systemic amyloidosis
6
PTGS2
💬
6.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Ketoprofen
Ketoprofen
💬
6.
PTGS2
×
Name
Other Names
Ketoprofen
Ketoprofen (JP18/USP/INN)
Orudis (TN)
Ketoprofen
[1]
46
46
💬
6.
PTGS2
×
Disease ID
Name
46
Malignant rheumatoid arthritis
7
PTGS2
💬
7.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Indomethacin
Indomethacin
💬
7.
PTGS2
×
Name
Other Names
Indomethacin
Indomethacin (USP)
Indometacin (JP18/INN)
Aconip (TN)
Indocin (TN)
Indomethacin
[3]
225
225
,
271
,
298
💬
7.
PTGS2
×
Disease ID
Name
225
Congenital nephrogenic diabetes insipidus
271
Ankylosing spondylitis
298
Hereditary pancreatitis
8
PTGS2
💬
8.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Acetaminophen
Acetaminophen
💬
8.
PTGS2
×
Name
Other Names
Acetaminophen
Acetaminophen (JP18/USP)
Paracetamol (INN)
Tylenol (TN)
OFIRMEV
GOOD NEIGHBOR PHARMACY PAIN RELIEF
Acetaminophen
[15]
3
3
,
6
,
11
,
13
,
34
,
35
,
46
,
49
,
51
,
70
,
86
,
222
,
256
,
271
,
337
💬
8.
PTGS2
×
Disease ID
Name
3
Spinal muscular atrophy
6
Parkinson disease
11
Myasthenia gravis
13
Multiple sclerosis/Neuromyelitis optica
34
Neurofibromatosis
35
Pemphigus
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
51
Scleroderma
70
Spinal stenosis
86
Pulmonary arterial hypertension
222
Primary nephrotic syndrome
256
Muscle glycogenosis
271
Ankylosing spondylitis
337
Homocystinuria
9
PTGS2
💬
9.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Etodolac
Etodolac
💬
9.
PTGS2
×
Name
Other Names
Etodolac
Etodolac (JP18/USP/INN)
Lodine (TN)
Etodolac
[1]
46
46
💬
9.
PTGS2
×
Disease ID
Name
46
Malignant rheumatoid arthritis
10
PTGS2
💬
10.
PTGS2
×
Name
Full Name
PTGS2
prostaglandin-endoperoxide synthase 2
[22]
Arachidonic acid metabolism
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling pathway
,
C-type lectin receptor signaling pathway
,
IL-17 signaling pathway
,
TNF signaling pathway
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Regulation of lipolysis in adipocytes
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
,
Leishmaniasis
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Pathways in cancer
,
Chemical carcinogenesis - DNA adducts
,
MicroRNAs in cancer
,
Small cell lung cancer
[22]
Arachidonic acid metabolism
,
Metabolic pathways
,
NF-kappa B signaling pathway
,
VEGF signaling p
...
Flurbiprofen
Flurbiprofen
💬
10.
PTGS2
×
Name
Other Names
Flurbiprofen
Flurbiprofen (JP18/USP/INN)
Ansaid (TN)
Flurbiprofen
[3]
13
13
,
21
,
46
💬
10.
PTGS2
×
Disease ID
Name
13
Multiple sclerosis/Neuromyelitis optica
21
Mitochondrial disease
46
Malignant rheumatoid arthritis