Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 DDC 💬 [9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Carbidopa 💬 Carbidopa [7] 6, 13, 17, 90, 140, 164, 201 💬
2 DDC 💬 [9] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Benserazide 💬 Benserazide [1] 6 💬
3 DHFR 💬 [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance Methotrexate 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
4 DHODH 💬 [3] Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors Leflunomide 💬 Leflunomide [12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬
5 DHODH 💬 [3] Pyrimidine metabolism, Metabolic pathways, Biosynthesis of cofactors Teriflunomide 💬 Teriflunomide [3] 13, 25, 26 💬
6 DMD 💬 [4] Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Eteplirsen 💬 Eteplirsen [1] 113 💬
7 DMD 💬 [4] Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Drisapersen 💬 Drisapersen [1] 113 💬
8 DMD 💬 [4] Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Viltolarsen 💬 Viltolarsen [1] 113 💬
9 DMD 💬 [4] Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Golodirsen 💬 Golodirsen [1] 113 💬
10 DMD 💬 [4] Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Casimersen 💬 Casimersen [1] 113 💬
11 DNMT1 💬 [3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer Decitabine 💬 Decitabine [3] 13, 60, 63 💬
12 DNMT3A 💬 [3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer Decitabine 💬 Decitabine [3] 13, 60, 63 💬
13 DNMT3B 💬 [3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer Decitabine 💬 Decitabine [3] 13, 60, 63 💬
14 DPEP1 💬 - Cilastatin 💬 Cilastatin [2] 60, 299 💬
15 DPP4 💬 [1] Protein digestion and absorption Sitagliptin 💬 Sitagliptin [4] 6, 75, 233, 299 💬
16 DPP4 💬 [1] Protein digestion and absorption Saxagliptin 💬 Saxagliptin [1] 299 💬
17 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
18 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Flupentixol 💬 Flupentixol [1] 97 💬
19 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Apomorphine 💬 Apomorphine [3] 5, 6, 7 💬
20 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
21 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Pergolide 💬 Pergolide [1] 6 💬
22 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Dexpramipexole 💬 Dexpramipexole [1] 2 💬
23 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Tavapadon 💬 Tavapadon [1] 6 💬
24 DRD1 💬 [10] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Morphine addiction, Alcoholism Foslevodopa 💬 Foslevodopa [1] 6 💬
25 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
26 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Haloperidol 💬 Haloperidol [1] 8 💬
27 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Chlorpromazine 💬 Chlorpromazine [1] 254 💬
28 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Risperidone 💬 Risperidone [5] 8, 156, 179, 187, 206 💬
29 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Olanzapine 💬 Olanzapine [2] 2, 8 💬
30 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pimozide 💬 Pimozide [1] 2 💬
31 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Metoclopramide 💬 Metoclopramide [2] 46, 51 💬
32 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Cabergoline 💬 Cabergoline [3] 6, 74, 75 💬
33 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Flupentixol 💬 Flupentixol [1] 97 💬
34 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
35 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Sulpiride 💬 Sulpiride [2] 6, 70 💬
36 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Terguride 💬 Terguride [2] 51, 86 💬
37 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Trifluoperazine maleate 💬 Trifluoperazine [2] 283, 284 💬
38 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Domperidone 💬 Domperidone [5] 6, 13, 17, 51, 230 💬
39 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Iloperidone 💬 Iloperidone [1] 6 💬
40 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Bromocriptine 💬 Bromocriptine [2] 6, 74 💬
41 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pramipexole 💬 Pramipexole [3] 2, 6, 20 💬
42 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Rotigotine 💬 Rotigotine [1] 6 💬
43 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Piribedil 💬 Piribedil [1] 6 💬
44 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Melperone 💬 Melperone [1] 6 💬
45 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Apomorphine 💬 Apomorphine [3] 5, 6, 7 💬
46 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Buspirone 💬 Buspirone [2] 6, 51 💬
47 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Domperidone maleate 💬 Domperidone [5] 6, 13, 17, 51, 230 💬
48 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
49 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Lisuride 💬 Lisuride [2] 6, 86 💬
50 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pergolide 💬 Pergolide [1] 6 💬
51 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Quetiapine 💬 Quetiapine [2] 6, 13 💬
52 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Ropinirole 💬 Ropinirole [4] 2, 6, 74, 309 💬
53 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Tiapride 💬 Tiapride [1] 8 💬
54 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Trifluoperazine 💬 Trifluoperazine [2] 283, 284 💬
55 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pardoprunox 💬 Pardoprunox [1] 6 💬
56 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Dexpramipexole 💬 Dexpramipexole [1] 2 💬
57 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Pridopidine 💬 Pridopidine [3] 2, 6, 8 💬
58 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Cariprazine 💬 Cariprazine [1] 21 💬
59 DRD2 💬 [8] Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Foslevodopa 💬 Foslevodopa [1] 6 💬
60 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
61 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Olanzapine 💬 Olanzapine [2] 2, 8 💬
62 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Aripiprazole 💬 Aripiprazole [2] 6, 206 💬
63 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Pramipexole 💬 Pramipexole [3] 2, 6, 20 💬
64 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Piribedil 💬 Piribedil [1] 6 💬
65 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
66 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Lisuride 💬 Lisuride [2] 6, 86 💬
67 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Ropinirole 💬 Ropinirole [4] 2, 6, 74, 309 💬
68 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Pardoprunox 💬 Pardoprunox [1] 6 💬
69 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Dexpramipexole 💬 Dexpramipexole [1] 2 💬
70 DRD3 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Foslevodopa 💬 Foslevodopa [1] 6 💬
71 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
72 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Clozapine 💬 Clozapine [1] 6 💬
73 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Olanzapine 💬 Olanzapine [2] 2, 8 💬
74 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Pramipexole 💬 Pramipexole [3] 2, 6, 20 💬
75 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
76 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Lisuride 💬 Lisuride [2] 6, 86 💬
77 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Ropinirole 💬 Ropinirole [4] 2, 6, 74, 309 💬
78 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Dexpramipexole 💬 Dexpramipexole [1] 2 💬
79 DRD4 💬 [2] Neuroactive ligand-receptor interaction, Dopaminergic synapse Foslevodopa 💬 Foslevodopa [1] 6 💬
80 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Levodopa 💬 Levodopa [6] 6, 17, 90, 140, 164, 201 💬
81 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Dopamine 💬 Dopamine [4] 6, 7, 74, 299 💬
82 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Dexpramipexole 💬 Dexpramipexole [1] 2 💬
83 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Tavapadon 💬 Tavapadon [1] 6 💬
84 DRD5 💬 [4] Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopaminergic synapse Foslevodopa 💬 Foslevodopa [1] 6 💬
85 DHFR2 💬 [5] One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, Antifolate resistance Methotrexate 💬 Methotrexate [38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬