Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A [1] SCN5A 💬 |
Mexiletine Mexiletine 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 💬 |
2 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
PGR [1] PGR 💬 |
Ulipristal Ulipristal 💬 |
Ulipristal | 010 [1] 10 💬 💬 |
3 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
4 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
OPRD1 [1] OPRD1 💬 |
Naltrexone Naltrexone 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬 |
5 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PGR [1] PGR 💬 |
Ulipristal Ulipristal 💬 |
Ulipristal | 010 [1] 10 💬 💬 |
6 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A [1] SCN1A 💬 |
Mexiletine Mexiletine 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 💬 |
7 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
8 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
OPRM1 [1] OPRM1 💬 |
Naltrexone Naltrexone 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬 |
9 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
PGR [1] PGR 💬 |
Ulipristal Ulipristal 💬 |
Ulipristal | 010 [1] 10 💬 💬 |
10 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
11 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
12 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
13 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
OPRM1 [1] OPRM1 💬 |
Naltrexone Naltrexone 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬 |
14 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
15 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OPRD1 [3] OPRD1, OPRK1, OPRM1 💬 |
Naltrexone Naltrexone 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬 |
16 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PGR [1] PGR 💬 |
Ulipristal Ulipristal 💬 |
Ulipristal | 010 [1] 10 💬 💬 |
17 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR [1] PGR 💬 |
Ulipristal Ulipristal 💬 |
Ulipristal | 010 [1] 10 💬 💬 |
18 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
OPRD1 [1] OPRD1 💬 |
Naltrexone Naltrexone 💬 |
Naltrexone | 006 [13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬 |
19 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABBR1 [2] GABBR1, GABBR2 💬 |
Baclofen Baclofen 💬 |
Baclofen | 002 [8] 2 , 10, 13, 18, 65, 70, 149, 206 💬 💬 |
20 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A [3] SCN2A, SCN3A, SCN9A 💬 |
Mexiletine Mexiletine 💬 |
Mexiletine | 001 [5] 1 , 2 , 10, 113, 114 💬 💬 |