Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Adrenergic signaling in cardiomyocytes 💬
[1] SCN5A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬 💬
2 Breast cancer 💬
[1] PGR 💬 Ulipristal 💬 Ulipristal [1] 10 💬 💬
3 cAMP signaling pathway 💬
[2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
4 cGMP-PKG signaling pathway 💬
[1] OPRD1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬
5 Chemical carcinogenesis - receptor activation 💬
[1] PGR 💬 Ulipristal 💬 Ulipristal [1] 10 💬 💬
6 Dopaminergic synapse 💬
[1] SCN1A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬 💬
7 Estrogen signaling pathway 💬
[2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
8 Estrogen signaling pathway 💬
[1] OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬
9 Estrogen signaling pathway 💬
[1] PGR 💬 Ulipristal 💬 Ulipristal [1] 10 💬 💬
10 GABAergic synapse 💬
[2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
11 GnRH secretion 💬
[2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
12 Morphine addiction 💬
[2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
13 Morphine addiction 💬
[1] OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬
14 Neuroactive ligand-receptor interaction 💬
[2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
15 Neuroactive ligand-receptor interaction 💬
[3] OPRD1, OPRK1, OPRM1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬
16 Oocyte meiosis 💬
[1] PGR 💬 Ulipristal 💬 Ulipristal [1] 10 💬 💬
17 Progesterone-mediated oocyte maturation 💬
[1] PGR 💬 Ulipristal 💬 Ulipristal [1] 10 💬 💬
18 Sphingolipid signaling pathway 💬
[1] OPRD1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬
19 Taste transduction 💬
[2] GABBR1, GABBR2 💬 Baclofen 💬 Baclofen [8]  2 , 10, 13, 18, 65, 70, 149, 206 💬 💬
20 Taste transduction 💬
[3] SCN2A, SCN3A, SCN9A 💬 Mexiletine 💬 Mexiletine [5]  1 ,  2 , 10, 113, 114 💬 💬