Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
2 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 19 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
3 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
4 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
5 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
6 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
7 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
8 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
9 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
10 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
11 | Arachidonic acid metabolism 💬 4 genes, 26 drugs (DrugBank) and 43 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
12 | beta-Alanine metabolism 💬 4 genes, 3 drugs (DrugBank) and 17 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
13 | Butanoate metabolism 💬 4 genes, 2 drugs (DrugBank) and 16 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
14 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
15 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
16 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
17 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
18 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
19 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
TNNC2 [1] TNNC2 💬 |
Reldesemtiv Reldesemtiv 💬 |
Reldesemtiv | 002 [2] 2 , 3 💬 💬 |
20 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
21 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
22 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
23 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
24 | Chemical carcinogenesis - DNA adducts 💬 1 gene, 24 drugs (DrugBank) and 40 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
25 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
26 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR [1] AR 💬 |
Testosterone Testosterone 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 💬 |
27 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
28 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
29 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIA2 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
30 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
31 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
KCNA4 [1] KCNA4 💬 |
Amifampridine Amifampridine 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 💬 |
32 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
KCNA4 [1] KCNA4 💬 |
Dalfampridine Dalfampridine 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 💬 |
33 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
34 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
KCNA4 [1] KCNA4 💬 |
Amifampridine Amifampridine 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 💬 |
35 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
KCNA4 [1] KCNA4 💬 |
Dalfampridine Dalfampridine 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 💬 |
36 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MSTN [1] MSTN 💬 |
Apitegromab Apitegromab 💬 |
Apitegromab | 003 [1] 3 💬 💬 |
37 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MSTN [1] MSTN 💬 |
Taldefgrobep alfa Taldefgrobep alfa 💬 |
Talditercept alfa | 003 [1] 3 💬 💬 |
38 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
39 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
40 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
ABAT [3] ABAT, GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
41 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
42 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
43 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 25 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
44 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
45 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
46 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
47 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
48 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
49 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIA1 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
50 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
51 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
52 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
53 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
54 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
55 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
56 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
GRIA1 [3] GRIA1, GRIA2, GRIA3 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
57 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIA1 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
58 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G [3] CACNA1G, CACNA1H, CACNA1I 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
59 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT [4] ABAT, ALDH5A1, GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
60 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
61 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
62 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
63 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
64 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
65 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
66 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
67 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
68 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIA1 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
69 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 [1] NR3C1 💬 |
Prednisolone Prednisolone 💬 |
Prednisolone | 003 [42] 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 💬 |
70 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
71 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
72 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
73 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
74 | Nucleocytoplasmic transport 💬 2 genes, 2 drugs (DrugBank) and 2 diseases |
SMN2 [1] SMN2 💬 |
Risdiplam Risdiplam 💬 |
Risdiplam | 003 [1] 3 💬 💬 |
75 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
76 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR [1] AR 💬 |
Testosterone Testosterone 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 💬 |
77 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
78 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
79 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
80 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
81 | p53 signaling pathway 💬 5 genes, 4 drugs (DrugBank) and 13 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
82 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR [1] AR 💬 |
Testosterone Testosterone 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 💬 |
83 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
84 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
85 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIA1 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
86 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
87 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
88 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGS1 [1] PTGS1 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
89 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
90 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
91 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR [1] AR 💬 |
Testosterone Testosterone 💬 |
Testosterone | 001 [8] 1 , 2 , 3 , 13, 60, 76, 78, 113 💬 💬 |
92 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
93 | Pyrimidine metabolism 💬 4 genes, 7 drugs (DrugBank) and 36 diseases |
RRM2 [1] RRM2 💬 |
Hydroxyurea Hydroxyurea 💬 |
Hydroxyurea | 003 [8] 3 , 13, 19, 20, 65, 85, 86, 284 💬 💬 |
94 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
95 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 [3] GRIN1, GRIN2A, GRIN2B 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
96 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
97 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
98 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
99 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
100 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
101 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
GRIA1 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
102 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
103 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
104 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB2 [1] ADRB2 💬 |
Albuterol Albuterol 💬 |
Salbutamol | 003 [12] 3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬 💬 |
105 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
106 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
KCND2 [1] KCND2 💬 |
Amifampridine Amifampridine 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 💬 |
107 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
KCND2 [1] KCND2 💬 |
Dalfampridine Dalfampridine 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 💬 |
108 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS1 [2] PTGS1, PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
109 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
110 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
111 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
112 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIA1 [8] GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
113 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
KCNC3 [2] KCNC3, KCND3 💬 |
Amifampridine Amifampridine 💬 |
Amifampridine | 003 [3] 3 , 11, 12 💬 💬 |
114 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
KCNC3 [2] KCNC3, KCND3 💬 |
Dalfampridine Dalfampridine 💬 |
Dalfampridine | 003 [5] 3 , 4 , 6 , 13, 14 💬 💬 |
115 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A [2] GRIN2A, GRIN2B 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
116 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
Midazolam Midazolam 💬 |
Midazolam | 002 [12] 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 💬 |
117 | Taurine and hypotaurine metabolism 💬 2 genes, 1 drug (DrugBank) and 14 diseases |
GAD1 [2] GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
118 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
119 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
120 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
GRIA3 [1] GRIA3 💬 |
Riluzole Riluzole 💬 |
Riluzole | 002 [9] 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 💬 |
121 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
GAD1 [2] GAD1, GAD2 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
122 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1G [1] CACNA1G 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
123 | Valine, leucine and isoleucine degradation 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT [1] ABAT 💬 |
Valproic acid Valproic acid 💬 |
Valproic acid | 002 [14] 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 💬 |
124 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PTGS2 [1] PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 [15] 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
125 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PTGS2 [1] PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 [10] 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |