Target Gene/Pathway Pathway / Gene


Search results


No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
2 Alcoholism 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
3 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
4 Alzheimer disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
5 Amphetamine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
6 Amphetamine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
7 Amyotrophic lateral sclerosis 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
8 Amyotrophic lateral sclerosis 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
9 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
10 Calcium signaling pathway 💬
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
11 cAMP signaling pathway 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
12 cAMP signaling pathway 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
13 cGMP-PKG signaling pathway 💬
[3] ADRA2A, ADRA2B, ADRA2C 💬 Dexmedetomidine 💬 Dexmedetomidine [14]  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 💬
14 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
15 Circadian entrainment 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
16 Cocaine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
17 Cocaine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
18 Cortisol synthesis and secretion 💬
[1] KCNA4 💬 Dalfampridine 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬 💬
19 Cushing syndrome 💬
[1] KCNA4 💬 Dalfampridine 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬 💬
20 Dopaminergic synapse 💬
[2] GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
21 Dopaminergic synapse 💬
[2] GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
22 ECM-receptor interaction 💬
[1] SV2A 💬 Levetiracetam 💬 Levetiracetam [5]  2 ,  4 ,  6 , 13, 307 💬 💬
23 Glutamatergic synapse 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
24 Glutamatergic synapse 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
25 Huntington disease 💬
[2] GRIN1, GRIN2B 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
26 Huntington disease 💬
[2] GRIN1, GRIN2B 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
27 Long-term potentiation 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
28 Long-term potentiation 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
29 Neuroactive ligand-receptor interaction 💬
[3] ADRA2A, ADRA2B, ADRA2C 💬 Dexmedetomidine 💬 Dexmedetomidine [14]  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 💬
30 Neuroactive ligand-receptor interaction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
31 Neuroactive ligand-receptor interaction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
32 Nicotine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
33 Nicotine addiction 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
34 Pathways of neurodegeneration - multiple diseases 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
35 Pathways of neurodegeneration - multiple diseases 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
36 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
37 Prion disease 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
38 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
39 Rap1 signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
40 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
41 Ras signaling pathway 💬
[3] GRIN1, GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
42 Serotonergic synapse 💬
[1] KCND2 💬 Dalfampridine 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬 💬
43 Spinocerebellar ataxia 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
44 Spinocerebellar ataxia 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬
45 Spinocerebellar ataxia 💬
[2] KCNC3, KCND3 💬 Dalfampridine 💬 Dalfampridine [5]  3 ,  4 ,  6 , 13, 14 💬 💬
46 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine [3]  2 ,  4 , 70 💬 💬
47 Systemic lupus erythematosus 💬
[2] GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬 💬