Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
3 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
4 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
5 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
6 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
7 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
8 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
9 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
10 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
ADRA1A [1] ADRA1A 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
11 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
ADRA1A [1] ADRA1A 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
12 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
13 | Caffeine metabolism 💬 1 gene, 2 drugs (DrugBank) and 9 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
14 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
15 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
16 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
17 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
18 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
19 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
20 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
21 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
22 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
23 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
24 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
25 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
26 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
27 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
28 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
29 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
30 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
31 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
32 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
33 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
34 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
35 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
36 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
37 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
38 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
39 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
40 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
41 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
42 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Amiodarone Amiodarone 💬 |
Amiodarone | 028 [2] 28, 127 💬 💬 |
43 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Atenolol Atenolol 💬 |
Atenolol | 167 [1] 167 💬 💬 |
44 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Bisoprolol Bisoprolol 💬 |
Bisoprolol | 058 [4] 58, 67, 86, 113 💬 💬 |
45 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
46 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Celiprolol Celiprolol 💬 |
Celiprolol | 168 [1] 168 💬 💬 |
47 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Dipivefrin Dipivefrin 💬 |
Dipivefrin | 006 [1] 6 💬 💬 |
48 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
49 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Droxidopa Droxidopa 💬 |
Droxidopa | 005 [5] 5 , 6 , 17, 169, 170 💬 💬 |
50 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Ephedrine Ephedrine 💬 |
Ephedrine | 011 [1] 11 💬 💬 |
51 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Epinephrine Epinephrine 💬 |
Epinephrine | 046 [3] 46, 70, 96 💬 💬 |
52 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Esmolol Esmolol 💬 |
Esmolol | 058 [1] 58 💬 💬 |
53 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
54 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Nadolol Nadolol 💬 |
Nadolol | 006 [1] 6 💬 💬 |
55 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Nebivolol Nebivolol 💬 |
Nebivolol | 017 [4] 17, 85, 113, 167 💬 💬 |
56 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Noradrenaline Noradrenaline 💬 |
Norepinephrine | 022 [2] 22, 296 💬 💬 |
57 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Propranolol Propranolol 💬 |
Propranolol | 006 [6] 6 , 158, 167, 227, 278, 296 💬 💬 |
58 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Pseudoephedrine Pseudoephedrine 💬 |
Pseudoephedrine | 017 [1] 17 💬 💬 |
59 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
60 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 [1] ADRB1 💬 |
Timolol Timolol 💬 |
Timolol | 157 [2] 157, 227 💬 💬 |
61 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Amlodipine Amlodipine 💬 |
Amlodipine | 013 [4] 13, 51, 67, 298 💬 💬 |
62 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Cilnidipine Cilnidipine 💬 |
Cilnidipine | 067 [1] 67 💬 💬 |
63 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Diltiazem Diltiazem 💬 |
Diltiazem | 051 [3] 51, 58, 86 💬 💬 |
64 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Isradipine Isradipine 💬 |
Isradipine | 006 [1] 6 💬 💬 |
65 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nicardipine Nicardipine 💬 |
Nicardipine | 070 [2] 70, 86 💬 💬 |
66 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nifedipine Nifedipine 💬 |
Nifedipine | 050 [2] 50, 81 💬 💬 |
67 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Nilvadipine Nilvadipine 💬 |
Nilvadipine | 090 [1] 90 💬 💬 |
68 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Perhexiline Perhexiline 💬 |
Perhexiline | 058 [2] 58, 272 💬 💬 |
69 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Propiverine Propiverine 💬 |
Propiverine | 226 [1] 226 💬 💬 |
70 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Topiramate Topiramate 💬 |
Topiramate | 006 [6] 6 , 97, 140, 144, 156, 193 💬 💬 |
71 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA1C [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
Verapamil Verapamil 💬 |
Verapamil | 058 [4] 58, 96, 140, 167 💬 💬 |
72 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA2D1 [2] CACNA2D1, CACNA2D2 💬 |
Mirogabalin Mirogabalin 💬 |
Mirogabalin | 070 [1] 70 💬 💬 |
73 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
Gabapentin Gabapentin 💬 |
Gabapentin | 006 [5] 6 , 13, 19, 70, 298 💬 💬 |
74 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
CACNA2D1 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 |
Pregabalin Pregabalin 💬 |
Pregabalin | 013 [5] 13, 36, 46, 70, 298 💬 💬 |
75 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
DMD [1] DMD 💬 |
Casimersen Casimersen 💬 |
Casimersen | 113 [1] 113 💬 💬 |
76 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
DMD [1] DMD 💬 |
Drisapersen Drisapersen 💬 |
Drisapersen | 113 [1] 113 💬 💬 |
77 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
DMD [1] DMD 💬 |
Eteplirsen Eteplirsen 💬 |
Eteplirsen | 113 [1] 113 💬 💬 |
78 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
DMD [1] DMD 💬 |
Golodirsen Golodirsen 💬 |
Golodirsen | 113 [1] 113 💬 💬 |
79 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
DMD [1] DMD 💬 |
Viltolarsen Viltolarsen 💬 |
Viltolarsen | 113 [1] 113 💬 💬 |
80 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ITGA4 [1] ITGA4 💬 |
Firategrast Firategrast 💬 |
Firategrast | 013 [1] 13 💬 💬 |
81 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ITGA4 [1] ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 [6] 13, 15, 25, 46, 63, 96 💬 💬 |
82 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Abrilumab Abrilumab 💬 |
Abrilumab | 096 [2] 96, 97 💬 💬 |
83 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ITGA4 [2] ITGA4, ITGB7 💬 |
Vedolizumab Vedolizumab 💬 |
Vedolizumab | 094 [3] 94, 96, 97 💬 💬 |
84 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ITGB7 [1] ITGB7 💬 |
Etrolizumab Etrolizumab 💬 |
Etrolizumab | 096 [2] 96, 97 💬 💬 |
85 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
MYH7 [1] MYH7 💬 |
Mavacamten Mavacamten 💬 |
Mavacamten | 058 [1] 58 💬 💬 |
86 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TGFB1 [3] TGFB1, TGFB2, TGFB3 💬 |
Fresolimumab Fresolimumab 💬 |
Fresolimumab | 051 [3] 51, 85, 222 💬 💬 |
87 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
88 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
89 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
90 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
91 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
92 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
93 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 [1] 46 💬 💬 |
94 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 [1] 46 💬 💬 |
95 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
96 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 [5] 28, 51, 85, 227, 331 💬 💬 |
97 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF [1] TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 [20] 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
98 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
99 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
ADRB1 [1] ADRB1 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
100 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
101 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
102 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
103 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
104 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
105 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
106 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
107 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
108 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
109 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
110 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
111 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
112 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
113 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
114 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
115 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
116 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
117 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
118 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
119 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
120 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
121 | Peroxisome 💬 4 genes, 5 drugs (DrugBank) and 11 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
122 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
123 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬 |
Filgrastim Filgrastim 💬 |
Filgrastim | 002 [35] 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 💬 |
124 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF3R [1] CSF3R 💬 |
Lenograstim Lenograstim 💬 |
Lenograstim | 002 [7] 2 , 13, 16, 18, 19, 57, 65 💬 💬 |
125 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA [1] PPARA 💬 |
Bezafibrate Bezafibrate 💬 |
Bezafibrate | 020 [7] 20, 93, 94, 160, 296, 316, 324 💬 💬 |
126 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
XDH [1] XDH 💬 |
Allopurinol Allopurinol 💬 |
Allopurinol | 006 [7] 6 , 46, 57, 60, 66, 96, 97 💬 💬 |
127 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
128 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
129 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
130 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
131 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
132 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
133 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB1 [2] ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
134 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
135 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases |
ACE [1] ACE 💬 |
Benazepril Benazepril 💬 |
Benazepril | 049 [4] 49, 57, 218, 224 💬 💬 |
136 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 31 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |
137 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
138 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A [5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
139 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬 |
Dobutamine Dobutamine 💬 |
Dobutamine | 057 [4] 57, 58, 86, 215 💬 💬 |
140 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRB1 [1] ADRB1 💬 |
Metoprolol Metoprolol 💬 |
Metoprolol | 017 [6] 17, 57, 58, 113, 193, 226 💬 💬 |
141 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Carvedilol Carvedilol 💬 |
Carvedilol | 057 [4] 57, 86, 113, 210 💬 💬 |
142 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A [3] ADRA1A, ADRA1B, ADRA1D 💬 |
Doxazosin Doxazosin 💬 |
Doxazosin | 057 [2] 57, 67 💬 💬 |
143 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
AGTR1 [1] AGTR1 💬 |
Valsartan Valsartan 💬 |
Valsartan | 057 [7] 57, 58, 66, 75, 218, 222, 224 💬 💬 |