Target Gene/Pathway Pathway / Gene

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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

1

Transcriptional misregulation in cancer 💬

[1] CD40 💬

Bleselumab 💬

[1] 222 💬

2

Transcriptional misregulation in cancer 💬

[1] CD40 💬

[2] 49, 53 💬

3

Transcriptional misregulation in cancer 💬

[1] CD40 💬

Ravagalimab 💬

[2] 53, 97 💬

4

Transcriptional misregulation in cancer 💬

[1] CD86 💬

[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271 ...

Disease ID	Name
11	Myasthenia gravis;MG;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
41	Giant cell arteritis;Temporal arteritis;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
49	Systemic lupus erythematosus;SLE;
50	Dermatomyositis;Polymyositis;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
55	Relapsing polychondritis;
60	Aplastic anemia;
65	Primary immunodeficiency;
84	Sarcoidosis;
93	Primary biliary cholangitis;Primary biliary cirrhosis;PBC;
95	Autoimmune hepatitis;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
107	Juvenile idiopathic arthritis;JIA;
160	Congenital ichthyosis;
164	Oculocutaneous albinism;
222	Primary nephrotic syndrome;
271	Ankylosing spondylitis;Spondylarthritis ankylopoietica;
284	Diamond-Blackfan anemia;
285	Fanconi anemia;
300	IgG4-related disease;

5

Transcriptional misregulation in cancer 💬

[1] CD86 💬

Belatacept 💬

[1] 46 💬

6

Transcriptional misregulation in cancer 💬

[3] CSF1R, FLT1, FLT3 💬

[2] 28, 34 💬

7

Transcriptional misregulation in cancer 💬

[2] CSF1R, FLT3 💬

Pexidartinib 💬

[1] 34 💬

8

Transcriptional misregulation in cancer 💬

[1] CSF2 💬

[1] 46 💬

9

Transcriptional misregulation in cancer 💬

[1] ELANE 💬

Sivelestat 💬

[3] 13, 85, 96 💬

10

Transcriptional misregulation in cancer 💬

[1] FLT1 💬

[1] 34 💬

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