Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank Disease ID
1 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Aminophylline 💬 Aminophylline [1] 63 💬 💬
2 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Caffeine 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
3 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Caffeine hydrate 💬 Caffeine [8]  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
4 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
5 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Theophylline 💬 Theophylline [2] 236, 299 💬 💬
6 Sphingolipid signaling pathway 💬
 [2] ADORA1, ADORA3 💬 Adenosine 💬 Adenosine [3] 13, 58, 65 💬 💬
7 Sphingolipid signaling pathway 💬
 [2] ADORA1, ADORA3 💬 Adenosine phosphate 💬 Adenosine phosphate [1] 46 💬 💬
8 Sphingolipid signaling pathway 💬
 [1] ADORA3 💬 Piclidenoson 💬 Piclidenoson [1] 46 💬 💬
9 Sphingolipid signaling pathway 💬
 [1] BCL2 💬 Venetoclax 💬 Venetoclax [1] 28 💬 💬
10 Sphingolipid signaling pathway 💬
 [1] FCER1A 💬 Omalizumab 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬 💬
11 Sphingolipid signaling pathway 💬
 [1] FYN 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
12 Sphingolipid signaling pathway 💬
 [1] FYN 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬 💬
13 Sphingolipid signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬 💬
14 Sphingolipid signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬 💬
15 Sphingolipid signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬 💬
16 Sphingolipid signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬 💬
17 Sphingolipid signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬 💬
18 Sphingolipid signaling pathway 💬
 [1] MAP3K5 💬 Selonsertib 💬 Selonsertib [1] 86 💬 💬
19 Sphingolipid signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod [2] 113, 222 💬 💬
20 Sphingolipid signaling pathway 💬
 [4] MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod [1]  8  💬 💬
21 Sphingolipid signaling pathway 💬
 [1] NFKB1 💬 Iguratimod 💬 Iguratimod [5] 46, 51, 53, 271, 300 💬 💬
22 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Loperamide 💬 Loperamide [2] 13, 97 💬 💬
23 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Nalbuphine 💬 Nalbuphine [1] 85 💬 💬
24 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Nalmefene 💬 Nalmefene [1]  6  💬 💬
25 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Naloxone 💬 Naloxone [2]  6 , 226 💬 💬
26 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Naltrexone 💬 Naltrexone [13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 💬
27 Sphingolipid signaling pathway 💬
 [1] OPRD1 💬 Oxycodone 💬 Oxycodone [5]  6 , 13, 70, 226, 298 💬 💬
28 Sphingolipid signaling pathway 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬 💬
29 Sphingolipid signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬 💬
30 Sphingolipid signaling pathway 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬 💬
31 Sphingolipid signaling pathway 💬
 [1] PRKCB 💬 Enzastaurin 💬 Enzastaurin [1] 168 💬 💬
32 Sphingolipid signaling pathway 💬
 [1] PRKCE 💬 Sotrastaurin 💬 Sotrastaurin [1] 97 💬 💬
33 Sphingolipid signaling pathway 💬
 [1] RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬 💬
34 Sphingolipid signaling pathway 💬
 [1] RELA 💬 Edasalonexent 💬 Edasalonexent [1] 113 💬 💬
35 Sphingolipid signaling pathway 💬
 [2] ROCK1, ROCK2 💬 Fasudil 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬 💬
36 Sphingolipid signaling pathway 💬
 [1] ROCK2 💬 Belumosudil 💬 Belumosudil [2] 51, 85 💬 💬
37 Sphingolipid signaling pathway 💬
 [1] S1PR1 💬 Cenerimod 💬 Cenerimod [1] 49 💬 💬
38 Sphingolipid signaling pathway 💬
 [1] S1PR1 💬 Fingolimod 💬 Fingolimod [3] 13, 14, 156 💬 💬
39 Sphingolipid signaling pathway 💬
 [1] S1PR1 💬 Ponesimod 💬 Ponesimod [1] 13 💬 💬
40 Sphingolipid signaling pathway 💬
 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬 Amiselimod 💬 Amiselimod [1] 97 💬 💬
41 Sphingolipid signaling pathway 💬
 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬 Etrasimod 💬 Etrasimod [3] 96, 97, 98 💬 💬
42 Sphingolipid signaling pathway 💬
 [5] S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 💬 Ozanimod 💬 Ozanimod [3] 13, 96, 97 💬 💬
43 Sphingolipid signaling pathway 💬
 [2] S1PR1, S1PR5 💬 Siponimod 💬 Siponimod [2] 13, 50 💬 💬
44 Sphingolipid signaling pathway 💬
 [1] SMPD1 💬 Olipudase alfa 💬 Olipudase alfa [1] 19 💬 💬
45 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Adalimumab 💬 Adalimumab [17] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
46 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Certolizumab pegol 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
47 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Etanercept 💬 Etanercept [16] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
48 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Golimumab 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
49 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Infliximab 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
50 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Lenalidomide 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
51 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Ozoralizumab 💬 Ozoralizumab [1] 46 💬 💬
52 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Pegsunercept 💬 Pegsunercept [1] 46 💬 💬
53 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Pirfenidone 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
54 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Pomalidomide 💬 Pomalidomide [5] 28, 51, 85, 227, 331 💬 💬
55 Sphingolipid signaling pathway 💬
 [1] TNF 💬 Thalidomide 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬