140. ドラベ症候群 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 116 / 薬物数 : 65 - (DrugBank : 17) / 標的遺伝子数 : 50 - 標的パスウェイ数 : 64
薬物ごとの開発者（Primary Sponsor）、臨床試験情報（抜粋）です。
12-Lead ECG
Gillette Children's Specialty Healthcare
2017 Phase 1/Phase 2 NCT02815540 United States;
Ataluren
NYU Langone Health
2016 Phase 2 NCT02758626 United States;
CBD - Oral Solution, is known as Epidiolex, and is the approved name in the USA.
GW Research Ltd
2015 Phase 3 EUCTR2014-001834-27-PL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-NL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
Cannabidiol
GW Research Ltd
2021 Phase 4 NCT05044819 United States;
Gillette Children's Specialty Healthcare
2017 Phase 1/Phase 2 NCT02815540 United States;
Yonsei University
2020 Phase 3 NCT04611438 Korea, Republic of;
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2018 Phase 1/Phase 2 NCT03467113 United States;
Cannabidiol (CBD)
GW Research Ltd
2015 Phase 3 EUCTR2014-002939-34-NL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-002939-34-ES Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-PL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-NL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-GB Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-FR France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-ES France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 - EUCTR2014-000995-24-PL France;Poland;United Kingdom;United States;
2014 Phase 3 EUCTR2014-002939-34-GB Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2014 Phase 2;Phase 3 EUCTR2014-000995-24-GB France;Poland;United Kingdom;United States;
- Phase 3 EUCTR2014-002939-34-PL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
Cannabidiol Oral Solution
INSYS Therapeutics Inc
2017 Phase 3 NCT02318563 -
Carbidopa
Natsume Jun
2020 Phase 4 JPRN-jRCTs041190116 Japan;
Clobazam
H. Lundbeck A/S
2015 Phase 3 NCT02187809 Mexico;United States;
2015 Phase 3 NCT02174094 Mexico;United States;
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
DIACOMIT (Stiripentol)
Meiji Seika Pharma Co., Ltd.
2012 - JPRN-JapicCTI-205180 Japan;
EPX-100 (Clemizole HCl)
Epygenix
2020 Phase 2 NCT04462770 Canada;United States;
EPX-100 (Clemizole Hydrochloride)
Epygenix
2019 Phase 1 NCT04069689 United States;
FENFLURAMINE HYDROCHLORIDE
Zogenix International Limited
2019 Phase 3 EUCTR2019-001331-31-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
FENFLURAMINE HYDROCHLORIDE (colorless)
Zogenix International Limited
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
FENFLURAMINE HYDROCHLORIDE (red)
Zogenix International Limited
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
FRISIUM*30CPS
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
Fenfluramina Cloridrato
ZOGENIX INTERNATIONAL LTD
2016 Phase 3 EUCTR2015-004167-37-IT Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
Fenfluramina cloridrato
Zogenix International Limited
2019 Phase 3 EUCTR2019-001331-31-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
Fenfluramine
University of California, Los Angeles
2018 - NCT04437004 United States;
YAMAMOTO Hideichiro
2019 Phase 3 JPRN-jRCT2041200095 Australia;Belgium;Canda;Denmark;France;Germany;Italy;Japan;Korea;Netherland;Norway;Spain;Sweeded;UK;US;
Fenfluramine Hydrochloride
Zogenix, Inc.
2018 - NCT03780127 -
Fenfluramine hydrochloride
Zogenix International Limited
2019 Phase 3 JPRN-JapicCTI-194872 Japan, Europe, Australia;
Fenfluramine hydrochloride (colorless)
Zogenix International Limited
2020 Phase 3 EUCTR2019-001331-31-SE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2019-001331-31-PL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2019-001331-31-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Fenfluramine hydrochloride (red)
Zogenix International Limited
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
GWP42003-P
GW Research Ltd
2015 Phase 3 NCT02224703 Australia;Israel;Netherlands;Poland;Spain;United States;
2015 Phase 3 NCT02224573 -
2015 Phase 3 EUCTR2014-002939-34-NL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-002939-34-ES Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-PL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-NL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-GB Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-FR France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-ES France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 - EUCTR2014-000995-24-PL France;Poland;United Kingdom;United States;
2014 Phase 3 EUCTR2014-002939-34-GB Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2014 Phase 2;Phase 3 EUCTR2014-000995-24-GB France;Poland;United Kingdom;United States;
- Phase 3 EUCTR2014-002939-34-PL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
GWP42003-P 10 mg/kg/day Dose
GW Research Ltd
2014 Phase 2 NCT02091206 United Kingdom;United States;
GWP42003-P 20 mg/kg/day Dose
GW Research Ltd
2015 Phase 3 NCT02091375 France;Poland;United Kingdom;United States;
2014 Phase 2 NCT02091206 United Kingdom;United States;
GWP42003-P 5 mg/kg/day Dose
GW Research Ltd
2014 Phase 2 NCT02091206 United Kingdom;United States;
Levodopa
Natsume Jun
2020 Phase 4 JPRN-jRCTs041190116 Japan;
Lorcaserin
Eisai Inc.
2020 Phase 3 NCT04572243 Canada;United States;
2020 - NCT04457687 -
ME2080 (stiripentol)
Meiji Seika Pharma Co., Ltd. (formerly MEIJI SEIKA KAISHA Co., LTD.)
2010 Phase 3 JPRN-JapicCTI-101116 -
None at this time
Takeda Development Center Americas, Inc.
2019 Phase 2 EUCTR2018-002484-25-PT Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
2019 Phase 2 EUCTR2018-002484-25-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
Other antiepileptics
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
PEG
Nonomura Hidenori
2021 Phase 3 JPRN-jRCT2051210074 Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russia;Serbia;Spain;Ukraine;United Kingdom;United States;
Placebo
Zogenix International Limited
2019 Phase 3 JPRN-JapicCTI-194872 Japan, Europe, Australia;
STK-001
Stoke Therapeutics, Inc
2021 Phase 2 NCT04740476 United States;
STK-001 - Multiple Ascending Doses
Stoke Therapeutics, Inc
2020 Phase 1/Phase 2 NCT04442295 United States;
STK-001 - Single Ascending Doses
Stoke Therapeutics, Inc
2020 Phase 1/Phase 2 NCT04442295 United States;
Soticlestat
Ovid Therapeutics, Inc.
2019 Phase 2 EUCTR2018-002485-39-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
TAKEDA DEVELOPMENT CENTER AMERICAS INC.
2021 Phase 3 EUCTR2021-002480-22-IT Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Takeda
2022 Phase 3 NCT05163314 Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
2021 Phase 3 NCT04940624 Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
2018 Phase 2 NCT03635073 Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
Takeda Development Center Americas, Inc.
2021 Phase 3 EUCTR2021-002480-22-PL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-NL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-HU Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-GR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-ES Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-BE Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
- Phase 3 EUCTR2021-002480-22-LV Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
- Phase 3 EUCTR2021-002480-22-FR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Stiripentol
Children's Hospital Medical Center, Cincinnati
2013 - NCT01983722 United States;
Cook Children's Health Care System
2014 - NCT02239276 United States;
Mayo Clinic
2012 Phase 4 NCT01533506 United States;
University of Colorado, Denver
2013 - NCT01835314 United States;
Yushi InoueNational Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
2007 - JPRN-JMA-IIA00014 Japan;
Stiripentolo
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
TAK-935
Ovid Therapeutics, Inc.
2019 Phase 2 EUCTR2018-002485-39-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
TAKEDA DEVELOPMENT CENTER AMERICAS INC.
2021 Phase 3 EUCTR2021-002480-22-IT Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Takeda
2018 Phase 2 NCT03650452 Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
Takeda Development Center Americas, Inc
2022 Phase 3 EUCTR2021-002482-17-GR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
- Phase 3 EUCTR2021-002482-17-BE Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
- Phase 3 EUCTR2021-002480-22-Outside-EU/EEA Australia;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Takeda Development Center Americas, Inc.
2021 Phase 3 EUCTR2021-002480-22-PL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-NL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-HU Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-GR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-ES Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-BE Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2019 Phase 2 EUCTR2018-002484-25-PT Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
2019 Phase 2 EUCTR2018-002484-25-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
- Phase 3 EUCTR2021-002480-22-LV Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
- Phase 3 EUCTR2021-002480-22-FR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
TOPAMAX
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
Topiramate
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
Turmeric
NYU Langone Health
2018 - NCT03254680 United States;
Verapamil
Gillette Children's Specialty Healthcare
2012 Phase 2 NCT01607073 United States;
ZX008
ZOGENIX INTERNATIONAL LTD
2016 Phase 3 EUCTR2015-004167-37-IT Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
Zogenix International Limited
2020 Phase 3 EUCTR2019-001331-31-SE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 JPRN-JapicCTI-194872 Japan, Europe, Australia;
2019 Phase 3 EUCTR2019-001331-31-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-000474-38-GB Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2017 Phase 3 EUCTR2016-000474-38-ES Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2017 Phase 3 EUCTR2016-000474-38-DE Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-000474-38-NL Germany;Netherlands;Spain;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-SE Australia;Belgium;Denmark;France;Germany;Italy;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-GB Australia;Belgium;Denmark;France;Germany;Italy;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-ES Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-DK Australia;Belgium;Denmark;France;Germany;Italy;Japan;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-DE Australia;Belgium;Denmark;France;Germany;Italy;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-BE Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2019-001331-31-PL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2019-001331-31-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2015-004167-37-NO Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2015-004167-37-FR Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
ZX008 (Fenfluramine Hydrochloride)
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2017 Phase 3 NCT03299842 United States;
2016 Phase 3 NCT02823145 Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 NCT02682927 Canada;United States;
Zogenix, Inc.
2019 Phase 3 NCT03936777 Australia;Belgium;Canada;Denmark;France;Germany;Italy;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
ZX008 - 0.2 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02926898 Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 NCT02826863 Australia;Belgium;Denmark;France;Germany;Italy;Japan;Norway;Spain;Sweden;United Kingdom;
ZX008 - 0.4 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02926898 Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
ZX008 - 0.8 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02826863 Australia;Belgium;Denmark;France;Germany;Italy;Japan;Norway;Spain;Sweden;United Kingdom;
ZX008 - 20 mg/day maximum dose
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02926898 Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
ZX008 0.2 to 0.8 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2018 Phase 1/Phase 2 NCT03467113 United States;
Gillette Children's Specialty Healthcare
2017 Phase 1/Phase 2 NCT02815540 United States;
Ataluren
NYU Langone Health
2016 Phase 2 NCT02758626 United States;
CBD - Oral Solution, is known as Epidiolex, and is the approved name in the USA.
GW Research Ltd
2015 Phase 3 EUCTR2014-001834-27-PL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-NL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
Cannabidiol
GW Research Ltd
2021 Phase 4 NCT05044819 United States;
Gillette Children's Specialty Healthcare
2017 Phase 1/Phase 2 NCT02815540 United States;
Yonsei University
2020 Phase 3 NCT04611438 Korea, Republic of;
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2018 Phase 1/Phase 2 NCT03467113 United States;
Cannabidiol (CBD)
GW Research Ltd
2015 Phase 3 EUCTR2014-002939-34-NL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-002939-34-ES Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-PL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-NL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-GB Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-FR France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-ES France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 - EUCTR2014-000995-24-PL France;Poland;United Kingdom;United States;
2014 Phase 3 EUCTR2014-002939-34-GB Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2014 Phase 2;Phase 3 EUCTR2014-000995-24-GB France;Poland;United Kingdom;United States;
- Phase 3 EUCTR2014-002939-34-PL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
Cannabidiol Oral Solution
INSYS Therapeutics Inc
2017 Phase 3 NCT02318563 -
Carbidopa
Natsume Jun
2020 Phase 4 JPRN-jRCTs041190116 Japan;
Clobazam
H. Lundbeck A/S
2015 Phase 3 NCT02187809 Mexico;United States;
2015 Phase 3 NCT02174094 Mexico;United States;
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
DIACOMIT (Stiripentol)
Meiji Seika Pharma Co., Ltd.
2012 - JPRN-JapicCTI-205180 Japan;
EPX-100 (Clemizole HCl)
Epygenix
2020 Phase 2 NCT04462770 Canada;United States;
EPX-100 (Clemizole Hydrochloride)
Epygenix
2019 Phase 1 NCT04069689 United States;
FENFLURAMINE HYDROCHLORIDE
Zogenix International Limited
2019 Phase 3 EUCTR2019-001331-31-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
FENFLURAMINE HYDROCHLORIDE (colorless)
Zogenix International Limited
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
FENFLURAMINE HYDROCHLORIDE (red)
Zogenix International Limited
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
FRISIUM*30CPS
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
Fenfluramina Cloridrato
ZOGENIX INTERNATIONAL LTD
2016 Phase 3 EUCTR2015-004167-37-IT Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
Fenfluramina cloridrato
Zogenix International Limited
2019 Phase 3 EUCTR2019-001331-31-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
Fenfluramine
University of California, Los Angeles
2018 - NCT04437004 United States;
YAMAMOTO Hideichiro
2019 Phase 3 JPRN-jRCT2041200095 Australia;Belgium;Canda;Denmark;France;Germany;Italy;Japan;Korea;Netherland;Norway;Spain;Sweeded;UK;US;
Fenfluramine Hydrochloride
Zogenix, Inc.
2018 - NCT03780127 -
Fenfluramine hydrochloride
Zogenix International Limited
2019 Phase 3 JPRN-JapicCTI-194872 Japan, Europe, Australia;
Fenfluramine hydrochloride (colorless)
Zogenix International Limited
2020 Phase 3 EUCTR2019-001331-31-SE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2019-001331-31-PL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2019-001331-31-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Fenfluramine hydrochloride (red)
Zogenix International Limited
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
GWP42003-P
GW Research Ltd
2015 Phase 3 NCT02224703 Australia;Israel;Netherlands;Poland;Spain;United States;
2015 Phase 3 NCT02224573 -
2015 Phase 3 EUCTR2014-002939-34-NL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-002939-34-ES Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-PL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-NL Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-GB Australia;France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-FR France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-001834-27-ES France;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2015 - EUCTR2014-000995-24-PL France;Poland;United Kingdom;United States;
2014 Phase 3 EUCTR2014-002939-34-GB Israel;Netherlands;Poland;Spain;United Kingdom;United States;
2014 Phase 2;Phase 3 EUCTR2014-000995-24-GB France;Poland;United Kingdom;United States;
- Phase 3 EUCTR2014-002939-34-PL Australia;Israel;Netherlands;Poland;Spain;United Kingdom;United States;
GWP42003-P 10 mg/kg/day Dose
GW Research Ltd
2014 Phase 2 NCT02091206 United Kingdom;United States;
GWP42003-P 20 mg/kg/day Dose
GW Research Ltd
2015 Phase 3 NCT02091375 France;Poland;United Kingdom;United States;
2014 Phase 2 NCT02091206 United Kingdom;United States;
GWP42003-P 5 mg/kg/day Dose
GW Research Ltd
2014 Phase 2 NCT02091206 United Kingdom;United States;
Levodopa
Natsume Jun
2020 Phase 4 JPRN-jRCTs041190116 Japan;
Lorcaserin
Eisai Inc.
2020 Phase 3 NCT04572243 Canada;United States;
2020 - NCT04457687 -
ME2080 (stiripentol)
Meiji Seika Pharma Co., Ltd. (formerly MEIJI SEIKA KAISHA Co., LTD.)
2010 Phase 3 JPRN-JapicCTI-101116 -
None at this time
Takeda Development Center Americas, Inc.
2019 Phase 2 EUCTR2018-002484-25-PT Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
2019 Phase 2 EUCTR2018-002484-25-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
Other antiepileptics
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
PEG
Nonomura Hidenori
2021 Phase 3 JPRN-jRCT2051210074 Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russia;Serbia;Spain;Ukraine;United Kingdom;United States;
Placebo
Zogenix International Limited
2019 Phase 3 JPRN-JapicCTI-194872 Japan, Europe, Australia;
STK-001
Stoke Therapeutics, Inc
2021 Phase 2 NCT04740476 United States;
STK-001 - Multiple Ascending Doses
Stoke Therapeutics, Inc
2020 Phase 1/Phase 2 NCT04442295 United States;
STK-001 - Single Ascending Doses
Stoke Therapeutics, Inc
2020 Phase 1/Phase 2 NCT04442295 United States;
Soticlestat
Ovid Therapeutics, Inc.
2019 Phase 2 EUCTR2018-002485-39-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
TAKEDA DEVELOPMENT CENTER AMERICAS INC.
2021 Phase 3 EUCTR2021-002480-22-IT Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Takeda
2022 Phase 3 NCT05163314 Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
2021 Phase 3 NCT04940624 Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
2018 Phase 2 NCT03635073 Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
Takeda Development Center Americas, Inc.
2021 Phase 3 EUCTR2021-002480-22-PL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-NL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-HU Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-GR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-ES Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-BE Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
- Phase 3 EUCTR2021-002480-22-LV Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
- Phase 3 EUCTR2021-002480-22-FR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Stiripentol
Children's Hospital Medical Center, Cincinnati
2013 - NCT01983722 United States;
Cook Children's Health Care System
2014 - NCT02239276 United States;
Mayo Clinic
2012 Phase 4 NCT01533506 United States;
University of Colorado, Denver
2013 - NCT01835314 United States;
Yushi InoueNational Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders
2007 - JPRN-JMA-IIA00014 Japan;
Stiripentolo
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
TAK-935
Ovid Therapeutics, Inc.
2019 Phase 2 EUCTR2018-002485-39-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
TAKEDA DEVELOPMENT CENTER AMERICAS INC.
2021 Phase 3 EUCTR2021-002480-22-IT Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Takeda
2018 Phase 2 NCT03650452 Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
Takeda Development Center Americas, Inc
2022 Phase 3 EUCTR2021-002482-17-GR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
- Phase 3 EUCTR2021-002482-17-BE Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United States;
- Phase 3 EUCTR2021-002480-22-Outside-EU/EEA Australia;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
Takeda Development Center Americas, Inc.
2021 Phase 3 EUCTR2021-002480-22-PL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-NL Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-HU Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-GR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-ES Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2021 Phase 3 EUCTR2021-002480-22-BE Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
2019 Phase 2 EUCTR2018-002484-25-PT Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
2019 Phase 2 EUCTR2018-002484-25-PL Australia;Canada;China;Israel;Poland;Portugal;Spain;United States;
- Phase 3 EUCTR2021-002480-22-LV Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
- Phase 3 EUCTR2021-002480-22-FR Australia;Belgium;Canada;China;France;Greece;Hungary;Italy;Japan;Latvia;Netherlands;Poland;Russian Federation;Serbia;Spain;Ukraine;United Kingdom;United States;
TOPAMAX
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
Topiramate
ISTITUTO C. MONDINO
2007 - EUCTR2007-003702-95-IT Italy;
Inserm-ISP Pole Recherches cliniques et thérapeutiques
2007 - EUCTR2007-002198-30-IT Italy;
Turmeric
NYU Langone Health
2018 - NCT03254680 United States;
Verapamil
Gillette Children's Specialty Healthcare
2012 Phase 2 NCT01607073 United States;
ZX008
ZOGENIX INTERNATIONAL LTD
2016 Phase 3 EUCTR2015-004167-37-IT Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
Zogenix International Limited
2020 Phase 3 EUCTR2019-001331-31-SE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2020 Phase 3 EUCTR2019-001331-31-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 JPRN-JapicCTI-194872 Japan, Europe, Australia;
2019 Phase 3 EUCTR2019-001331-31-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001331-31-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-NL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-002804-14-IT Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2017 Phase 3 EUCTR2016-000474-38-GB Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2017 Phase 3 EUCTR2016-000474-38-ES Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2017 Phase 3 EUCTR2016-000474-38-DE Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-GB Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-ES Australia;Belgium;Canada;Denmark;France;Germany;Italy;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-DK Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-002804-14-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 EUCTR2016-000474-38-NL Germany;Netherlands;Spain;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-SE Australia;Belgium;Denmark;France;Germany;Italy;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-GB Australia;Belgium;Denmark;France;Germany;Italy;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-ES Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-DK Australia;Belgium;Denmark;France;Germany;Italy;Japan;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-DE Australia;Belgium;Denmark;France;Germany;Italy;Norway;Spain;Sweden;Switzerland;United Kingdom;
2016 Phase 3 EUCTR2015-004167-37-BE Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2019-001331-31-PL Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2019-001331-31-BE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2016-002804-14-FR Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
- Phase 3 EUCTR2015-004167-37-NO Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2015-004167-37-FR Australia;Belgium;Denmark;France;Germany;Italy;Korea, Republic of;Norway;Spain;Sweden;Switzerland;United Kingdom;
Zogenix International Limited, a wholly owned subsidiary of Zogenix Inc.
2016 Phase 3 EUCTR2016-002804-14-DE Australia;Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
ZX008 (Fenfluramine Hydrochloride)
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2017 Phase 3 NCT03299842 United States;
2016 Phase 3 NCT02823145 Australia;Belgium;Canada;Denmark;France;Germany;Italy;Japan;Netherlands;Norway;Spain;Sweden;United Kingdom;United States;
2016 Phase 3 NCT02682927 Canada;United States;
Zogenix, Inc.
2019 Phase 3 NCT03936777 Australia;Belgium;Canada;Denmark;France;Germany;Italy;Mexico;Netherlands;Poland;Spain;Sweden;United Kingdom;United States;
ZX008 - 0.2 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02926898 Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
2016 Phase 3 NCT02826863 Australia;Belgium;Denmark;France;Germany;Italy;Japan;Norway;Spain;Sweden;United Kingdom;
ZX008 - 0.4 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02926898 Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
ZX008 - 0.8 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02826863 Australia;Belgium;Denmark;France;Germany;Italy;Japan;Norway;Spain;Sweden;United Kingdom;
ZX008 - 20 mg/day maximum dose
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2016 Phase 3 NCT02926898 Canada;France;Germany;Netherlands;Spain;United Kingdom;United States;
ZX008 0.2 to 0.8 mg/kg/day
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
2018 Phase 1/Phase 2 NCT03467113 United States;