145. ウエスト症候群 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 43 / 薬物数 : 52 - (DrugBank : 15) / 標的遺伝子数 : 28 - 標的パスウェイ数 : 26
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
18 FDG
National Institute of Neurological Disorders and Stroke (NINDS)
1992 - NCT00001325 United States;
ACTH
All India Institute of Medical Sciences, New Delhi
2022 Phase 2/Phase 3 NCT05279118 India;
Wayne State University
2013 Phase 4 NCT02092883 United States;
AMZ002
Amzell B.V.
- Phase 3 EUCTR2021-003015-26-FR France;Germany;Poland;Spain;United States;
Adrenocorticotropin hormone
Ann & Robert H Lurie Children's Hospital of Chicago
2011 - NCT01367964 United States;
Cannabidiol (CBD)
GW Research Ltd
- Phase 3 EUCTR2015-004904-50-PL Hungary;Italy;Poland;United Kingdom;United States;
Cannabidiol Oral Solution
Benuvia Therapeutics Inc.
2018 Phase 3 NCT03421496 United States;
Combination therapy with vigabatrin and prednisolone
Kullasate Sakpichaisakul
2020 - NCT04302116 Thailand;
Cosyntropin Injectable Suspension 1 MG/ML + vigabatrin
University of Colorado, Denver
2018 Phase 3 NCT03347526 United States;
Cosyntropin Injectable Suspension, 1 mg/mL
University of Colorado, Denver
2018 Phase 3 NCT03347526 United States;
Decortin H
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
Fenfluramine
University of California, Los Angeles
2020 Phase 2 NCT04289467 United States;
GWP42003-P
GW Research Ltd
2017 Phase 3 NCT02954887 Poland;United States;
2017 Phase 3 NCT02953548 Poland;United States;
- Phase 3 EUCTR2015-004904-50-PL Hungary;Italy;Poland;United Kingdom;United States;
Ganaxolone
Marinus Pharmaceuticals
2007 Phase 2 NCT00442104 United States;
2007 Phase 2 NCT00441896 United States;
Marinus Pharmaceuticals, Inc.
2007 - EUCTR2006-004285-13-CZ Czech Republic;
Marinus Pharmceuticals, Inc.
2007 - EUCTR2006-004286-33-CZ Czech Republic;
- Phase 2 EUCTR2006-004286-33-PL Czech Republic;Poland;
Intravenous Methylprednisolone
Suvasini Sharma
2019 Phase 2/Phase 3 NCT03876444 India;
JBPOS0101
Bio-Pharm Solutions Co., Ltd.
2019 Phase 2 NCT03976076 United States;
Ketogenic diet
All India Institute of Medical Sciences, New Delhi
2022 Phase 2/Phase 3 NCT05279118 India;
M071754
Alfresa Pharma Corporation
2012 Phase 4 JPRN-JapicCTI-142559 -
2012 Phase 3 JPRN-JapicCTI-142558 -
Alfresa Pharma Corporation and Sanofi KK
- Phase 3 EUCTR2017-000611-17-Outside-EU/EEA Japan;
- Phase 3 EUCTR2017-000230-62-Outside-EU/EEA Japan;
Melatonin
Department of Pediatrics, The First Medical Center, General Hospital of the People's Liberation Army of China
2020 Phase 0 ChiCTR2000036208 China;
Modified Atkins diet
All India Institute of Medical Sciences, New Delhi
2009 Phase 2/Phase 3 NCT01006811 India;
Oral Pednisolone
Suvasini Sharma
2019 Phase 2/Phase 3 NCT03876444 India;
Oral prednisolone
Lady Hardinge Medical College
2012 Phase 3 NCT01575639 India;
Prednisolone
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
The Hospital for Sick Children
2017 Phase 3 NCT02299115 Canada;
Pyridoxine plus prednisolone
Lady Hardinge Medical College
2012 Phase 3 NCT01828437 India;
Radiprodil
UCB Biopharma S.P.R.L.
2017 Phase 2 NCT02829827 Belgium;Bulgaria;France;Germany;United Kingdom;
UCB Biopharma SPRL
2017 Phase 2 EUCTR2016-002107-26-FR Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-DE Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-BG Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-GB Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-BE Belgium;Bulgaria;France;Germany;United Kingdom;
SABRIL SACHETS
Royal United Hospital Bath NHS Trust
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
SOLUBLE PREDNISOLONE TABLETS
Royal United Hospital Bath NHS Trust
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
SPT3162
Marinus Pharmceuticals, Inc.
2007 - EUCTR2006-004286-33-CZ Czech Republic;
- Phase 2 EUCTR2006-004286-33-PL Czech Republic;Poland;
Sabril
Amzell B.V.
- Phase 3 EUCTR2021-003015-26-FR France;Germany;Poland;Spain;United States;
Sabril granules for oral use
TARGEON
- Phase 2 EUCTR2014-000360-17-FR France;
Sabrilex
Kirsi Mikkonen/Helsinki University Hospital
2018 Phase 4 EUCTR2017-004775-30-FI Finland;
Sabril®
Lundbeck LLC
2009 - NCT01073579 -
Synacthen Depot
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
Tetracosactide Acetate
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
Tricaprilin
Cerecin
2021 Phase 1 NCT04727970 Australia;Singapore;
UCB3491
UCB Biopharma SPRL
2017 Phase 2 EUCTR2016-002107-26-FR Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-DE Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-BG Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-GB Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-BE Belgium;Bulgaria;France;Germany;United Kingdom;
VGB-ST soluble tablets
TARGEON
- Phase 2 EUCTR2014-000360-17-FR France;
Vigabatrin
Alfresa Pharma Corporation
2012 Phase 4 JPRN-JapicCTI-142559 -
2012 Phase 3 JPRN-JapicCTI-142558 -
Amzell B.V.
- Phase 3 EUCTR2021-003015-26-FR France;Germany;Poland;Spain;United States;
Benuvia Therapeutics Inc.
2018 Phase 3 NCT03421496 United States;
Lundbeck LLC
2012 Phase 4 NCT01413711 -
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
The Hospital for Sick Children
2017 Phase 3 NCT02299115 Canada;
Vigabatrin Tablets
Kullasate Sakpichaisakul
2020 - NCT04302116 Thailand;
Vigabatrin: Vigabatrin new ST formulation then Sabril®
Orphelia Pharma
2014 - NCT02220114 France;
Vitamin B1
Faculty of Pediatrics, the first Medical Centre, Chinese PLA General Hospital
2021 Phase 0 ChiCTR2100045702 China;
National Institute of Neurological Disorders and Stroke (NINDS)
1992 - NCT00001325 United States;
ACTH
All India Institute of Medical Sciences, New Delhi
2022 Phase 2/Phase 3 NCT05279118 India;
Wayne State University
2013 Phase 4 NCT02092883 United States;
AMZ002
Amzell B.V.
- Phase 3 EUCTR2021-003015-26-FR France;Germany;Poland;Spain;United States;
Adrenocorticotropin hormone
Ann & Robert H Lurie Children's Hospital of Chicago
2011 - NCT01367964 United States;
Cannabidiol (CBD)
GW Research Ltd
- Phase 3 EUCTR2015-004904-50-PL Hungary;Italy;Poland;United Kingdom;United States;
Cannabidiol Oral Solution
Benuvia Therapeutics Inc.
2018 Phase 3 NCT03421496 United States;
Combination therapy with vigabatrin and prednisolone
Kullasate Sakpichaisakul
2020 - NCT04302116 Thailand;
Cosyntropin Injectable Suspension 1 MG/ML + vigabatrin
University of Colorado, Denver
2018 Phase 3 NCT03347526 United States;
Cosyntropin Injectable Suspension, 1 mg/mL
University of Colorado, Denver
2018 Phase 3 NCT03347526 United States;
Decortin H
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
Fenfluramine
University of California, Los Angeles
2020 Phase 2 NCT04289467 United States;
GWP42003-P
GW Research Ltd
2017 Phase 3 NCT02954887 Poland;United States;
2017 Phase 3 NCT02953548 Poland;United States;
- Phase 3 EUCTR2015-004904-50-PL Hungary;Italy;Poland;United Kingdom;United States;
Ganaxolone
Marinus Pharmaceuticals
2007 Phase 2 NCT00442104 United States;
2007 Phase 2 NCT00441896 United States;
Marinus Pharmaceuticals, Inc.
2007 - EUCTR2006-004285-13-CZ Czech Republic;
Marinus Pharmceuticals, Inc.
2007 - EUCTR2006-004286-33-CZ Czech Republic;
- Phase 2 EUCTR2006-004286-33-PL Czech Republic;Poland;
Intravenous Methylprednisolone
Suvasini Sharma
2019 Phase 2/Phase 3 NCT03876444 India;
JBPOS0101
Bio-Pharm Solutions Co., Ltd.
2019 Phase 2 NCT03976076 United States;
Ketogenic diet
All India Institute of Medical Sciences, New Delhi
2022 Phase 2/Phase 3 NCT05279118 India;
M071754
Alfresa Pharma Corporation
2012 Phase 4 JPRN-JapicCTI-142559 -
2012 Phase 3 JPRN-JapicCTI-142558 -
Alfresa Pharma Corporation and Sanofi KK
- Phase 3 EUCTR2017-000611-17-Outside-EU/EEA Japan;
- Phase 3 EUCTR2017-000230-62-Outside-EU/EEA Japan;
Melatonin
Department of Pediatrics, The First Medical Center, General Hospital of the People's Liberation Army of China
2020 Phase 0 ChiCTR2000036208 China;
Modified Atkins diet
All India Institute of Medical Sciences, New Delhi
2009 Phase 2/Phase 3 NCT01006811 India;
Oral Pednisolone
Suvasini Sharma
2019 Phase 2/Phase 3 NCT03876444 India;
Oral prednisolone
Lady Hardinge Medical College
2012 Phase 3 NCT01575639 India;
Prednisolone
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
The Hospital for Sick Children
2017 Phase 3 NCT02299115 Canada;
Pyridoxine plus prednisolone
Lady Hardinge Medical College
2012 Phase 3 NCT01828437 India;
Radiprodil
UCB Biopharma S.P.R.L.
2017 Phase 2 NCT02829827 Belgium;Bulgaria;France;Germany;United Kingdom;
UCB Biopharma SPRL
2017 Phase 2 EUCTR2016-002107-26-FR Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-DE Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-BG Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-GB Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-BE Belgium;Bulgaria;France;Germany;United Kingdom;
SABRIL SACHETS
Royal United Hospital Bath NHS Trust
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
SOLUBLE PREDNISOLONE TABLETS
Royal United Hospital Bath NHS Trust
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
SPT3162
Marinus Pharmceuticals, Inc.
2007 - EUCTR2006-004286-33-CZ Czech Republic;
- Phase 2 EUCTR2006-004286-33-PL Czech Republic;Poland;
Sabril
Amzell B.V.
- Phase 3 EUCTR2021-003015-26-FR France;Germany;Poland;Spain;United States;
Sabril granules for oral use
TARGEON
- Phase 2 EUCTR2014-000360-17-FR France;
Sabrilex
Kirsi Mikkonen/Helsinki University Hospital
2018 Phase 4 EUCTR2017-004775-30-FI Finland;
Sabril®
Lundbeck LLC
2009 - NCT01073579 -
Synacthen Depot
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
Tetracosactide Acetate
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
Tricaprilin
Cerecin
2021 Phase 1 NCT04727970 Australia;Singapore;
UCB3491
UCB Biopharma SPRL
2017 Phase 2 EUCTR2016-002107-26-FR Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-DE Belgium;Bulgaria;France;Germany;United Kingdom;
2017 Phase 2 EUCTR2016-002107-26-BG Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-GB Belgium;Bulgaria;France;Germany;United Kingdom;
2016 Phase 2 EUCTR2016-002107-26-BE Belgium;Bulgaria;France;Germany;United Kingdom;
VGB-ST soluble tablets
TARGEON
- Phase 2 EUCTR2014-000360-17-FR France;
Vigabatrin
Alfresa Pharma Corporation
2012 Phase 4 JPRN-JapicCTI-142559 -
2012 Phase 3 JPRN-JapicCTI-142558 -
Amzell B.V.
- Phase 3 EUCTR2021-003015-26-FR France;Germany;Poland;Spain;United States;
Benuvia Therapeutics Inc.
2018 Phase 3 NCT03421496 United States;
Lundbeck LLC
2012 Phase 4 NCT01413711 -
Royal United Hospital Bath NHS Trust
2010 Phase 4 EUCTR2006-000788-27-DE Australia;Germany;New Zealand;Switzerland;United Kingdom;
2006 Phase 4 EUCTR2006-000788-27-GB Germany;United Kingdom;
The Hospital for Sick Children
2017 Phase 3 NCT02299115 Canada;
Vigabatrin Tablets
Kullasate Sakpichaisakul
2020 - NCT04302116 Thailand;
Vigabatrin: Vigabatrin new ST formulation then Sabril®
Orphelia Pharma
2014 - NCT02220114 France;
Vitamin B1
Faculty of Pediatrics, the first Medical Centre, Chinese PLA General Hospital
2021 Phase 0 ChiCTR2100045702 China;