274. 骨形成不全症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 91 / 薬物数 : 101 - (DrugBank : 20) / 標的遺伝子数 : 11 - 標的パスウェイ数 : 48
薬物ごとの開発者（Primary Sponsor）、臨床試験情報（抜粋）です。
00244301
AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
2015 Phase 2 EUCTR2015-002622-39-IT Italy;
ACLASTA
Schriners Hospitals for Children
2012 - EUCTR2011-000745-21-BE Belgium;Canada;United States;
AMG 162
AMGEN INC.
2019 Phase 3 EUCTR2018-000550-21-IT Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-IT Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc
2020 Phase 3 EUCTR2018-000550-21-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2018-000550-21-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc.
2015 Phase 3 EUCTR2014-000184-40-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- - EUCTR2014-000184-40-Outside-EU/EEA Australia;Canada;United States;
Amgen, Inc.
2020 Phase 3 EUCTR2014-000184-40-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-000184-40-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
AMG 785
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Amgen Inc.
2021 Phase 1 EUCTR2017-004972-74-GR France;Germany;Greece;Hungary;Italy;Spain;Turkey;
2021 Phase 1 EUCTR2017-004972-74-DE France;Germany;Greece;Hungary;Italy;Spain;Turkey;
2020 Phase 1 EUCTR2017-004972-74-HU France;Germany;Greece;Hungary;Italy;Spain;Turkey;
ANTI-SCLEROSTIN MONOCLONAL ANTIBODY
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
2017 Phase 2 EUCTR2016-005096-27-FR Canada;Denmark;France;United Kingdom;United States;
Aclasta
Bente Langdahl, consultant, ass. professor, PhD, DMSc
2011 Phase 2 EUCTR2011-002811-27-DK Denmark;
Actonel 5mg Film Coated Tablets
Sheffield Children's NHS Foundation Trust
2017 Phase 2 EUCTR2016-003606-14-GB United Kingdom;
Actonel Once a Week 35 mg film-coated tablets
Sheffield Children's NHS Foundation Trust
2017 Phase 2 EUCTR2016-003606-14-GB United Kingdom;
Actonel/Optinate 5mg film-coated tablets
Procter & Gamble Ltd
2006 - EUCTR2004-000485-13-FI Czech Republic;Denmark;Finland;Hungary;Spain;
Alendronate
Indiana University School of Medicine
1999 Phase 4 NCT00159419 United States;
Peking Union Medical College Hospital
2007 Phase 4 NCT02303873 -
Tohoku University School of Medicine, Department of Pediatrics
2013 - JPRN-UMIN000010615 Japan;
Alendronic acid
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Alternative osteoporosis medications
Amgen
2018 Phase 3 NCT03638128 Australia;Belgium;Canada;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Anti-sclerostin monoclonal antibody
Novartis Pharma Services AG
2012 - EUCTR2011-001465-41-DE Canada;Germany;
2011 Phase 1;Phase 2 EUCTR2011-001465-41-BE Belgium;Canada;Germany;
BOOST cells
Christian Medical College, Vellore, India
2019 Phase 1/Phase 2 NCT04623606 India;
Karolinska Institutet
2019 Phase 1/Phase 2 NCT03706482 Sweden;
2018 Phase 1;Phase 2 EUCTR2015-003699-60-SE Sweden;
BPS804
Mereo BioPharma
2017 Phase 2 NCT03216486 United States;
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
2017 Phase 2 EUCTR2016-005096-27-FR Canada;Denmark;France;United Kingdom;United States;
Novartis Pharma Services AG
2012 - EUCTR2011-001465-41-DE Canada;Germany;
2011 Phase 1;Phase 2 EUCTR2011-001465-41-BE Belgium;Canada;Germany;
Ultragenyx Pharmaceutical Inc
2017 Phase 2 NCT03118570 Canada;Denmark;France;United Kingdom;United States;
2011 Phase 2 NCT01417091 Belgium;Canada;Germany;United States;
Bisphosphonates
Luca Sangiorgi
2013 - NCT04115774 Italy;
Blood sample
Hospices Civils de Lyon
2019 - NCT04009733 France;
Bone marrow transplant
St. Jude Children's Research Hospital
2004 - NCT00187018 United States;
Bonefos
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Busulfan
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
CALCIO CARBONATO/COLECALCIFEROLO
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
CALCIUM D3 SANDOZ - 1000 MG + 880 U.I. COMPRESSE EFFERVESCENTI 30 COMPRESSE DIVISIBILI
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Calcichew D3
University of Edinburgh
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
Calcichew tablets
Sheffield Children's NHS Foundation Trust
2017 Phase 2 NCT03208582 United Kingdom;
Calcium
Amgen
2021 Phase 1 NCT04545554 Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
Celulas madre mesenquimales troncales adultas alogenicas de médula ósea no expandida
Itziar Astigarraga Aguirre
2013 - EUCTR2012-002553-38-ES Spain;
Clasteon
University of Edinburgh
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
Cyclophosphamide
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
Cyclosporin
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
Células mesenquimales troncales adultas alogénicas de médula ósea no expandidas(ref cruzada PEI nº 12-088)
Itziar Astigarraga Aguirre
2013 - EUCTR2012-002553-38-ES Spain;
Denosumab
Amgen
2018 Phase 3 NCT03638128 Australia;Belgium;Canada;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2015 Phase 3 NCT02352753 Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
University of Cologne
2013 Phase 2 NCT01799798 Germany;
Denosumab - - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand
Amgen Inc.
- - EUCTR2014-000184-40-Outside-EU/EEA Australia;Canada;United States;
Denosumab - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand
AMGEN INC.
2019 Phase 3 EUCTR2018-000550-21-IT Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-IT Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc
2020 Phase 3 EUCTR2018-000550-21-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2018-000550-21-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc.
2015 Phase 3 EUCTR2014-000184-40-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen, Inc.
2020 Phase 3 EUCTR2014-000184-40-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-000184-40-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
Denusomab
University of Cologne
2013 - EUCTR2012-002887-29-DE Germany;
Disodium Pamidronate 15mg (15mg strength)
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Evenity
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Expanded human first trimester fetal liver-derived mesenchymal stem cells
Karolinska Institutet
2018 Phase 1;Phase 2 EUCTR2015-003699-60-SE Sweden;
Forsteo
Bente Langdahl, consultant, ass. professor, PhD, DMSc
2011 Phase 2 EUCTR2011-002811-27-DK Denmark;
Fresolimumab
Baylor College of Medicine
2017 Phase 1 NCT03064074 United States;
Fultium-D3 800IU capsules
University of Edinburgh
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
GENOTROPIN*1TBF 5,3MG (16UI)
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
H05AA02
Bente Langdahl, consultant, ass. professor, PhD, DMSc
2011 Phase 2 EUCTR2011-002811-27-DK Denmark;
High-dose vitamin D (2000 IU per day)
Louis-Nicolas Veilleux Ph.D.
2012 Phase 4 NCT01713231 Canada;
Humatrope
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1991 Phase 3 NCT00001305 United States;
Ibandronic acid
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Mesenchymal Stem Cell Transplantation
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
Mesenchymal Stem Cells
Hospital de Cruces
2014 Phase 1 NCT02172885 Spain;
Mesenchymal Stromal Cells
Nationwide Children's Hospital
2010 Phase 1 NCT01061099 United States;
NERIXIA*INFUS IV CONC 2F
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
Optinate 5 mg filmcoated tablets
Procter & Gamble Ltd
2007 - EUCTR2004-000485-13-DK Czech Republic;Denmark;Finland;Hungary;Spain;
PLASMASAFE - SOLUZIONE PER INFUSIONE 1 SACCA DA 200 ML
AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
2015 Phase 2 EUCTR2015-002622-39-IT Italy;
Pamidronate
Indiana University School of Medicine
1999 Phase 4 NCT00159419 United States;
Kobe University Hospital
2018 - JPRN-UMIN000031290 Japan;
University of New Mexico
2007 - NCT00655681 United States;
Pamidronate (Aredia)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2000 Phase 3 NCT00005901 Canada;United States;
Prolia
University of Cologne
2013 - EUCTR2012-002887-29-DE Germany;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Risedronate Oral Tablet
Hospital for Special Surgery, New York
2019 Phase 4 NCT04152551 United States;
Risedronate Sodium
Sheffield Children's NHS Foundation Trust
2017 Phase 2 NCT03208582 United Kingdom;
2017 Phase 2 EUCTR2016-003606-14-GB United Kingdom;
Risedronate sodium
Procter & Gamble Ltd
2007 - EUCTR2004-000485-13-DK Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-HU Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-FI Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-CZ Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-BE Belgium;Czech Republic;Denmark;Finland;Hungary;Spain;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Risedronate sodium (Actonel)
Warner Chilcott
2004 Phase 3 NCT00106028 Australia;Belgium;Chile;Czech Republic;Finland;Germany;Hungary;Italy;Poland;South Africa;Spain;United Kingdom;United States;
Risedronato sódico
Procter & Gamble Ltd
2006 - EUCTR2004-000485-13-ES Czech Republic;Denmark;Finland;Hungary;Spain;
Risedronic acid
Procter & Gamble Ltd
2007 - EUCTR2004-000485-13-DK Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-HU Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-FI Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-CZ Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-BE Belgium;Czech Republic;Denmark;Finland;Hungary;Spain;
Romosozumab
Amgen
2021 Phase 1 NCT04545554 Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
SAR439459
Sanofi
2022 Phase 1 NCT05231668 -
Setrusumab
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
Ultragenyx Pharmaceutical Inc
2022 Phase 2/Phase 3 NCT05125809 Australia;Canada;Denmark;Italy;United Kingdom;United States;
Somatropin
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
Standard-dose vitamin D (400IU per day)
Louis-Nicolas Veilleux Ph.D.
2012 Phase 4 NCT01713231 Canada;
Teriparatide
University of Aarhus
2012 Phase 2 NCT01679080 Denmark;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Teriparatide (FORTEO)
Oregon Health and Science University
2005 Phase 4 NCT00131469 United States;
Teriparatide Pen Injector
University of Edinburgh
2016 Phase 4 NCT03735537 Ireland;United Kingdom;
VARI
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
Vitamin D
Amgen
2021 Phase 1 NCT04545554 Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
Vitamina D e calcio
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
XGEVA - 120 MG - SOLUZIONE INIETTABILE - USO SOTTOCUTANEO - FLACONCINO (VETRO) - 1.7 ML 4 FLACONCINI
AMGEN INC.
- Phase 3 EUCTR2014-000184-40-IT Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
ZOL446
Novartis Pharma AG
2005 - EUCTR2004-001666-40-HU Hungary;United Kingdom;
2005 - EUCTR2004-001666-40-GB Hungary;United Kingdom;
- Phase 2 EUCTR2004-001666-40-BE Belgium;Hungary;United Kingdom;
Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion, generic medicinal product.
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion,generic medicinal product
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Zoledronic acid
Novartis Pharma AG
2005 - EUCTR2004-001666-40-HU Hungary;United Kingdom;
2005 - EUCTR2004-001666-40-GB Hungary;United Kingdom;
- Phase 2 EUCTR2004-001666-40-BE Belgium;Hungary;United Kingdom;
Schriners Hospitals for Children
2012 - EUCTR2011-000745-21-BE Belgium;Canada;United States;
University of Aarhus
2012 Phase 2 NCT01679080 Denmark;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Zometa
Novartis
- - EUCTR2015-003539-37-Outside-EU/EEA United States;
Ácido risedrónico
Procter & Gamble Ltd
2006 - EUCTR2004-000485-13-ES Czech Republic;Denmark;Finland;Hungary;Spain;
AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
2015 Phase 2 EUCTR2015-002622-39-IT Italy;
ACLASTA
Schriners Hospitals for Children
2012 - EUCTR2011-000745-21-BE Belgium;Canada;United States;
AMG 162
AMGEN INC.
2019 Phase 3 EUCTR2018-000550-21-IT Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-IT Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc
2020 Phase 3 EUCTR2018-000550-21-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2018-000550-21-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc.
2015 Phase 3 EUCTR2014-000184-40-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- - EUCTR2014-000184-40-Outside-EU/EEA Australia;Canada;United States;
Amgen, Inc.
2020 Phase 3 EUCTR2014-000184-40-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-000184-40-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
AMG 785
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Amgen Inc.
2021 Phase 1 EUCTR2017-004972-74-GR France;Germany;Greece;Hungary;Italy;Spain;Turkey;
2021 Phase 1 EUCTR2017-004972-74-DE France;Germany;Greece;Hungary;Italy;Spain;Turkey;
2020 Phase 1 EUCTR2017-004972-74-HU France;Germany;Greece;Hungary;Italy;Spain;Turkey;
ANTI-SCLEROSTIN MONOCLONAL ANTIBODY
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
2017 Phase 2 EUCTR2016-005096-27-FR Canada;Denmark;France;United Kingdom;United States;
Aclasta
Bente Langdahl, consultant, ass. professor, PhD, DMSc
2011 Phase 2 EUCTR2011-002811-27-DK Denmark;
Actonel 5mg Film Coated Tablets
Sheffield Children's NHS Foundation Trust
2017 Phase 2 EUCTR2016-003606-14-GB United Kingdom;
Actonel Once a Week 35 mg film-coated tablets
Sheffield Children's NHS Foundation Trust
2017 Phase 2 EUCTR2016-003606-14-GB United Kingdom;
Actonel/Optinate 5mg film-coated tablets
Procter & Gamble Ltd
2006 - EUCTR2004-000485-13-FI Czech Republic;Denmark;Finland;Hungary;Spain;
Alendronate
Indiana University School of Medicine
1999 Phase 4 NCT00159419 United States;
Peking Union Medical College Hospital
2007 Phase 4 NCT02303873 -
Tohoku University School of Medicine, Department of Pediatrics
2013 - JPRN-UMIN000010615 Japan;
Alendronic acid
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Alternative osteoporosis medications
Amgen
2018 Phase 3 NCT03638128 Australia;Belgium;Canada;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Anti-sclerostin monoclonal antibody
Novartis Pharma Services AG
2012 - EUCTR2011-001465-41-DE Canada;Germany;
2011 Phase 1;Phase 2 EUCTR2011-001465-41-BE Belgium;Canada;Germany;
BOOST cells
Christian Medical College, Vellore, India
2019 Phase 1/Phase 2 NCT04623606 India;
Karolinska Institutet
2019 Phase 1/Phase 2 NCT03706482 Sweden;
2018 Phase 1;Phase 2 EUCTR2015-003699-60-SE Sweden;
BPS804
Mereo BioPharma
2017 Phase 2 NCT03216486 United States;
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
2017 Phase 2 EUCTR2016-005096-27-FR Canada;Denmark;France;United Kingdom;United States;
Novartis Pharma Services AG
2012 - EUCTR2011-001465-41-DE Canada;Germany;
2011 Phase 1;Phase 2 EUCTR2011-001465-41-BE Belgium;Canada;Germany;
Ultragenyx Pharmaceutical Inc
2017 Phase 2 NCT03118570 Canada;Denmark;France;United Kingdom;United States;
2011 Phase 2 NCT01417091 Belgium;Canada;Germany;United States;
Bisphosphonates
Luca Sangiorgi
2013 - NCT04115774 Italy;
Blood sample
Hospices Civils de Lyon
2019 - NCT04009733 France;
Bone marrow transplant
St. Jude Children's Research Hospital
2004 - NCT00187018 United States;
Bonefos
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Busulfan
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
CALCIO CARBONATO/COLECALCIFEROLO
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
CALCIUM D3 SANDOZ - 1000 MG + 880 U.I. COMPRESSE EFFERVESCENTI 30 COMPRESSE DIVISIBILI
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Calcichew D3
University of Edinburgh
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
Calcichew tablets
Sheffield Children's NHS Foundation Trust
2017 Phase 2 NCT03208582 United Kingdom;
Calcium
Amgen
2021 Phase 1 NCT04545554 Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
Celulas madre mesenquimales troncales adultas alogenicas de médula ósea no expandida
Itziar Astigarraga Aguirre
2013 - EUCTR2012-002553-38-ES Spain;
Clasteon
University of Edinburgh
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
Cyclophosphamide
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
Cyclosporin
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
Células mesenquimales troncales adultas alogénicas de médula ósea no expandidas(ref cruzada PEI nº 12-088)
Itziar Astigarraga Aguirre
2013 - EUCTR2012-002553-38-ES Spain;
Denosumab
Amgen
2018 Phase 3 NCT03638128 Australia;Belgium;Canada;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2015 Phase 3 NCT02352753 Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
University of Cologne
2013 Phase 2 NCT01799798 Germany;
Denosumab - - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand
Amgen Inc.
- - EUCTR2014-000184-40-Outside-EU/EEA Australia;Canada;United States;
Denosumab - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand
AMGEN INC.
2019 Phase 3 EUCTR2018-000550-21-IT Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-IT Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc
2020 Phase 3 EUCTR2018-000550-21-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2020 Phase 3 EUCTR2018-000550-21-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2019 Phase 3 EUCTR2018-000550-21-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2018 Phase 3 EUCTR2018-000550-21-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2018-000550-21-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen Inc.
2015 Phase 3 EUCTR2014-000184-40-BE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Amgen, Inc.
2020 Phase 3 EUCTR2014-000184-40-PL Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2015 Phase 3 EUCTR2014-000184-40-GB Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-HU Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-ES Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-DE Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
2014 Phase 3 EUCTR2014-000184-40-CZ Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-FR Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
- Phase 3 EUCTR2014-000184-40-BG Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
Denusomab
University of Cologne
2013 - EUCTR2012-002887-29-DE Germany;
Disodium Pamidronate 15mg (15mg strength)
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Evenity
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Expanded human first trimester fetal liver-derived mesenchymal stem cells
Karolinska Institutet
2018 Phase 1;Phase 2 EUCTR2015-003699-60-SE Sweden;
Forsteo
Bente Langdahl, consultant, ass. professor, PhD, DMSc
2011 Phase 2 EUCTR2011-002811-27-DK Denmark;
Fresolimumab
Baylor College of Medicine
2017 Phase 1 NCT03064074 United States;
Fultium-D3 800IU capsules
University of Edinburgh
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
GENOTROPIN*1TBF 5,3MG (16UI)
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
H05AA02
Bente Langdahl, consultant, ass. professor, PhD, DMSc
2011 Phase 2 EUCTR2011-002811-27-DK Denmark;
High-dose vitamin D (2000 IU per day)
Louis-Nicolas Veilleux Ph.D.
2012 Phase 4 NCT01713231 Canada;
Humatrope
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1991 Phase 3 NCT00001305 United States;
Ibandronic acid
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Mesenchymal Stem Cell Transplantation
St. Jude Children's Research Hospital
1995 Phase 1 NCT00705120 United States;
Mesenchymal Stem Cells
Hospital de Cruces
2014 Phase 1 NCT02172885 Spain;
Mesenchymal Stromal Cells
Nationwide Children's Hospital
2010 Phase 1 NCT01061099 United States;
NERIXIA*INFUS IV CONC 2F
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
Optinate 5 mg filmcoated tablets
Procter & Gamble Ltd
2007 - EUCTR2004-000485-13-DK Czech Republic;Denmark;Finland;Hungary;Spain;
PLASMASAFE - SOLUZIONE PER INFUSIONE 1 SACCA DA 200 ML
AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
2015 Phase 2 EUCTR2015-002622-39-IT Italy;
Pamidronate
Indiana University School of Medicine
1999 Phase 4 NCT00159419 United States;
Kobe University Hospital
2018 - JPRN-UMIN000031290 Japan;
University of New Mexico
2007 - NCT00655681 United States;
Pamidronate (Aredia)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2000 Phase 3 NCT00005901 Canada;United States;
Prolia
University of Cologne
2013 - EUCTR2012-002887-29-DE Germany;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Risedronate Oral Tablet
Hospital for Special Surgery, New York
2019 Phase 4 NCT04152551 United States;
Risedronate Sodium
Sheffield Children's NHS Foundation Trust
2017 Phase 2 NCT03208582 United Kingdom;
2017 Phase 2 EUCTR2016-003606-14-GB United Kingdom;
Risedronate sodium
Procter & Gamble Ltd
2007 - EUCTR2004-000485-13-DK Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-HU Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-FI Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-CZ Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-BE Belgium;Czech Republic;Denmark;Finland;Hungary;Spain;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Risedronate sodium (Actonel)
Warner Chilcott
2004 Phase 3 NCT00106028 Australia;Belgium;Chile;Czech Republic;Finland;Germany;Hungary;Italy;Poland;South Africa;Spain;United Kingdom;United States;
Risedronato sódico
Procter & Gamble Ltd
2006 - EUCTR2004-000485-13-ES Czech Republic;Denmark;Finland;Hungary;Spain;
Risedronic acid
Procter & Gamble Ltd
2007 - EUCTR2004-000485-13-DK Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-HU Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-FI Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-CZ Czech Republic;Denmark;Finland;Hungary;Spain;
2006 - EUCTR2004-000485-13-BE Belgium;Czech Republic;Denmark;Finland;Hungary;Spain;
Romosozumab
Amgen
2021 Phase 1 NCT04545554 Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
SAR439459
Sanofi
2022 Phase 1 NCT05231668 -
Setrusumab
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
Ultragenyx Pharmaceutical Inc
2022 Phase 2/Phase 3 NCT05125809 Australia;Canada;Denmark;Italy;United Kingdom;United States;
Somatropin
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
Standard-dose vitamin D (400IU per day)
Louis-Nicolas Veilleux Ph.D.
2012 Phase 4 NCT01713231 Canada;
Teriparatide
University of Aarhus
2012 Phase 2 NCT01679080 Denmark;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Teriparatide (FORTEO)
Oregon Health and Science University
2005 Phase 4 NCT00131469 United States;
Teriparatide Pen Injector
University of Edinburgh
2016 Phase 4 NCT03735537 Ireland;United Kingdom;
VARI
AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
2005 - EUCTR2004-005275-42-IT Italy;
Vitamin D
Amgen
2021 Phase 1 NCT04545554 Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
Vitamina D e calcio
AMGEN INC.
2020 Phase 1 EUCTR2017-004972-74-IT France;Germany;Greece;Hungary;Italy;Spain;Turkey;
XGEVA - 120 MG - SOLUZIONE INIETTABILE - USO SOTTOCUTANEO - FLACONCINO (VETRO) - 1.7 ML 4 FLACONCINI
AMGEN INC.
- Phase 3 EUCTR2014-000184-40-IT Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
ZOL446
Novartis Pharma AG
2005 - EUCTR2004-001666-40-HU Hungary;United Kingdom;
2005 - EUCTR2004-001666-40-GB Hungary;United Kingdom;
- Phase 2 EUCTR2004-001666-40-BE Belgium;Hungary;United Kingdom;
Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion, generic medicinal product.
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Mereo Biopharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-GB Canada;Denmark;France;United Kingdom;United States;
Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion,generic medicinal product
Mereo BioPharma 3 Ltd.
2017 Phase 2 EUCTR2016-005096-27-DK Canada;Denmark;France;United Kingdom;United States;
Zoledronic acid
Novartis Pharma AG
2005 - EUCTR2004-001666-40-HU Hungary;United Kingdom;
2005 - EUCTR2004-001666-40-GB Hungary;United Kingdom;
- Phase 2 EUCTR2004-001666-40-BE Belgium;Hungary;United Kingdom;
Schriners Hospitals for Children
2012 - EUCTR2011-000745-21-BE Belgium;Canada;United States;
University of Aarhus
2012 Phase 2 NCT01679080 Denmark;
University of Edinburgh
2021 Phase 4 EUCTR2016-003228-22-NL Ireland;Netherlands;United Kingdom;
2017 Phase 4 EUCTR2016-003228-22-IE Ireland;Netherlands;United Kingdom;
2016 Phase 4 EUCTR2016-003228-22-GB Ireland;United Kingdom;
Zometa
Novartis
- - EUCTR2015-003539-37-Outside-EU/EEA United States;
Ácido risedrónico
Procter & Gamble Ltd
2006 - EUCTR2004-000485-13-ES Czech Republic;Denmark;Finland;Hungary;Spain;