35. 天疱瘡 Disease details / Clinical trials / Drug dev / DR info


臨床試験数 : 99 / 薬物数 : 124 - (DrugBank : 36) / 標的遺伝子数 : 23 - 標的パスウェイ数 : 169

薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
ALXN1830   
   Alexion Pharmaceuticals
      2017   Phase 1/Phase 2   NCT03075904   United States;
ARGX-113   
   ARGEN-X BVBA
      2018   Phase 2   EUCTR2017-002333-40-IT   Germany;Hungary;Israel;Italy;Romania;Ukraine;
   ARGENX BV
      2020   Phase 3   EUCTR2020-002917-16-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
   argenx
      2017   Phase 2   NCT03334058   Germany;Hungary;Israel;Italy;Ukraine;
   argenx BV
      2021   Phase 3   EUCTR2020-002917-16-FR   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002917-16-HU   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002917-16-GR   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002917-16-BG   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-FR   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
   argenx BVBA
      2018   Phase 2   EUCTR2017-002333-40-DE   Germany;Hungary;Israel;Italy;Romania;Ukraine;
      2017   Phase 2   EUCTR2017-002333-40-HU   Germany;Hungary;Israel;Italy;Romania;Ukraine;
Acetaminophen/paracetamol   
   GlaxoSmithKline
      2015   Phase 3   NCT02613910   United States;
Ad26.COV2.S   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2021   Phase 2   NCT05000216   United States;
Antihistamine (cetirizine or equivalent)   
   GlaxoSmithKline
      2015   Phase 3   NCT02613910   United States;
Azathioprine   
   Dermatological Department, West China hospital, Sichuan University
      2016   Phase 1 study   ChiCTR-OIC-17011759   China;
   Tehran University of Medical Sciences
      2008   Phase 2   NCT00626678   Iran, Islamic Republic of;
BNT162b2   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2021   Phase 2   NCT05000216   United States;
CELLCEPT®   
   F. Hoffmann-La Roche Ltd
      2015   Phase 3   EUCTR2014-000382-41-IT   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-FR   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-ES   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-DE   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
Carboxymethylcellulose with ionic silver (Aquacel Ag)   
   Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C.
      2015   -   NCT02365675   Mexico;
CellCept 500 mg comprimidos recubiertos   
   Aspreva pharmaceuticals Corporation
      2006   -   EUCTR2004-000526-75-ES   Spain;
CellCept®500 mg comprimidos   
   Aspreva pharmaceuticals Corporation
      2006   -   EUCTR2004-000526-75-ES   Spain;
Cellcept® in autoimmune bullous dermatoses   
   University Hospital, Limoges
      2016   Phase 3   NCT02993133   France;
Cellulose acetate with petrolatum   
   Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C.
      2015   -   NCT02365675   Mexico;
Cohort 1: 1.0 x 10^8 PolyTregs   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2017   Phase 1   NCT03239470   United States;
Cohort 2: 2.5x10^8 PolyTregs   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2017   Phase 1   NCT03239470   United States;
Combination of Protein A Immunoadsorption, Rituximab, Dexamethasone plus Azathioprine   
   University of Luebeck
      2008   Phase 2   NCT00656656   Germany;
Corticosteroids'therapy   
   University Hospital, Rouen
      2019   Phase 3   NCT03790293   -
Cotton gauze with petrolatum   
   Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C.
      2015   -   NCT02365675   Mexico;
Cyclophosphamide   
   Johns Hopkins University
      1999   Phase 2   NCT00010413   United States;
   New York University School of Medicine
      2007   Phase 2   NCT00483119   United States;
DSG3-CAART   
   Cabaletta Bio
      2020   Phase 1   NCT04422912   United States;
Dapsone   
   Jacobus Pharmaceutical
      1996   Phase 2   NCT00429533   United States;
Dermoval   
   University Hospital, Rouen
      2001   -   NCT00213421   France;
Dexamethasone (50mg 1dd6, 3 consecutive days/month)   
   University Medical Centre Groningen
      2001   Phase 2/Phase 3   NCT00127764   Netherlands;
Dexamethasone 0.5mg/5ml solution in Mucolox™   
   University of California, San Francisco
      2020   Phase 2   NCT04540133   United States;
Efgartigimod   
   ARGEN-X BVBA
      2018   Phase 2   EUCTR2017-002333-40-IT   Germany;Hungary;Israel;Italy;Romania;Ukraine;
   argenx BVBA
      2018   Phase 2   EUCTR2017-002333-40-DE   Germany;Hungary;Israel;Italy;Romania;Ukraine;
      2017   Phase 2   EUCTR2017-002333-40-HU   Germany;Hungary;Israel;Italy;Romania;Ukraine;
Efgartigimod PH20 SC   
   ARGENX BV
      2020   Phase 3   EUCTR2020-002917-16-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
   argenx
      2021   Phase 3   NCT04598477   Australia;Bulgaria;China;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   NCT04598451   Australia;Bulgaria;China;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
   argenx BV
      2021   Phase 3   EUCTR2020-002917-16-FR   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-002917-16-DE   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
      2021   Phase 3   EUCTR2020-002915-23-DE   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002917-16-HU   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002917-16-GR   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002917-16-BG   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-HU   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-GR   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-FR   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-BG   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
Enbrel (Etanercept)   
   Massachusetts General Hospital
      2004   Phase 2   NCT00135720   United States;
Filgrastim   
   Johns Hopkins University
      1999   Phase 2   NCT00010413   United States;
GSK1841157   
   Glaxo Group Ltd
      2015   Phase 3   EUCTR2013-001370-20-PL   Australia;China;Croatia;France;Greece;Israel;Italy;Japan;Korea, Republic of;Poland;Russian Federation;Ukraine;United States;
      2015   -   EUCTR2013-001370-20-FR   Australia;China;Croatia;France;Israel;Italy;Japan;Korea, Republic of;Poland;Russian Federation;Ukraine;United States;
      2014   Phase 3   EUCTR2013-001370-20-IT   Australia;China;Croatia;France;Greece;Israel;Italy;Japan;Korea, Republic of;Poland;Russian Federation;Ukraine;United States;
      2014   Phase 3   EUCTR2013-001370-20-GR   Australia;China;Croatia;France;Greece;Israel;Italy;Japan;Korea, Republic of;Poland;Russian Federation;Ukraine;United States;
   Novartis Pharma AG
      2014   Phase 3   EUCTR2013-001370-20-HR   Australia;China;Croatia;France;Greece;Israel;Italy;Japan;Korea, Republic of;Poland;Russian Federation;Ukraine;United States;
General Corticotherapy   
   University Hospital, Rouen
      2009   Phase 3   NCT00784589   France;
Gold   
   Peking University School and Hospital of Stomatology
      2018   Phase 0   ChiCTR2100042023   China;
   Peking University stomatological hospital
      2018   Phase 0   ChiCTR2100042024   China;
Hematopoietic stem cell transplantation   
   Richard Burt, MD
      2002   Phase 1   NCT00278642   United States;
INCB050465 HYDROCHLORIDE   
   INCYTE CORPORATION
      2019   Phase 2   EUCTR2018-002146-37-IT   Canada;France;Italy;
   Incyte Corporation
      2019   Phase 2   EUCTR2018-002146-37-FR   Canada;France;Italy;
IS (B cell depletion therapy)   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2021   Phase 2   NCT05000216   United States;
IS (MMF or MPA)   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2021   Phase 2   NCT05000216   United States;
IS (MTX)   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2021   Phase 2   NCT05000216   United States;
IVIg   
   The University of Hong Kong
      2020   Phase 2   NCT04400994   Hong Kong;
Ianalumab   
   Novartis Pharma Services AG
      2013   Phase 2   EUCTR2013-001217-33-AT   Austria;Bulgaria;Taiwan;United States;
Imatinib   
   Kabashima Kenji
      2018   Phase 0   JPRN-jRCTs051180069   Japan;
Infliximab   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2006   Phase 2   NCT00283712   United States;
Intratect   
   Ruprecht-Karls-University Heidelberg
      2013   Phase 2   EUCTR2013-000211-24-DE   Germany;
Intravenous immunoglobulin   
   New York University School of Medicine
      2007   Phase 2   NCT00483119   United States;
KC706   
   Kemia, Inc
      2007   Phase 2   NCT00606749   United States;
MABTHERA®   
   F. Hoffmann-La Roche Ltd
      2015   Phase 3   EUCTR2014-000382-41-IT   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-FR   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-ES   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-DE   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
MTX   
   Institute of dermatology, Chinese Academyof Medical Sciences
      2011   -   ChiCTR-TRC-12003540   China;
      2011   -   ChiCTR-TRC-12003539   China;
Mabthéra   
   CHU-Hôpitaux de Rouen
      2009   -   EUCTR2008-005266-31-FR   France;
Mathéra   
   CHU-Hôpitaux de Rouen
      2009   -   EUCTR2008-005266-31-FR   France;
Methotrexate   
   Institute of dermatology, Chinese Academyof Medical Sciences
      2011   -   ChiCTR-TRC-12003539   China;
Methylprednisolone   
   West China Hospital, Sichuna University
      2019   -   ChiCTR1800020382   China;
Micofenolato mofetilo   
   Aspreva pharmaceuticals Corporation
      2006   -   EUCTR2004-000526-75-ES   Spain;
Moderna mRNA-1273   
   National Institute of Allergy and Infectious Diseases (NIAID)
      2021   Phase 2   NCT05000216   United States;
Mycophenolate Mofetil (MMF) 3 g/Day   
   Hoffmann-La Roche
      2004   Phase 3   NCT00683930   Canada;Germany;India;Israel;Switzerland;Turkey;Ukraine;United Kingdom;United States;
Mycophenolate Mofetil 2 g/Day   
   Hoffmann-La Roche
      2004   Phase 3   NCT00683930   Canada;Germany;India;Israel;Switzerland;Turkey;Ukraine;United Kingdom;United States;
Mycophenolate mofetil   
   F. Hoffmann-La Roche Ltd
      2015   Phase 3   EUCTR2014-000382-41-IT   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-FR   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-ES   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-DE   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
Nanocrystalline silver (Acticoat)   
   Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C.
      2015   -   NCT02365675   Mexico;
ONO-4059   
   ONO PHARMACEUTICAL CO.,LTD.
      2019   Phase 2   JPRN-JapicCTI-184231   Japan;
Ofatumumab   
   GlaxoSmithKline
      2015   Phase 3   NCT02613910   United States;
   Novartis Pharmaceuticals
      2013   Phase 3   NCT01920477   Australia;Croatia;France;Greece;Israel;Italy;Japan;Korea, Republic of;Poland;Romania;Russian Federation;Ukraine;United States;
PI-0824   
   Peptimmune
      2003   Phase 1   NCT00063752   United States;
PRN1008   
   Principia Biopharma
      2019   Phase 3   EUCTR2018-002261-19-GR   Argentina;Australia;Brazil;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Serbia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
      2019   Phase 3   EUCTR2018-002261-19-FR   Australia;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Serbia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
      2019   Phase 3   EUCTR2018-002261-19-ES   Australia;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Serbia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
   Principia Biopharma Inc.
      2019   Phase 3   EUCTR2018-002261-19-IT   Argentina;Australia;Brazil;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Serbia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
      2016   Phase 2   NCT02704429   Australia;Croatia;France;Greece;Israel;
PRN1008 (Rilzabrutinib)   
   Principia Biopharma
      2019   Phase 3   EUCTR2018-002261-19-HR   Argentina;Australia;Brazil;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Serbia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
      2019   Phase 3   EUCTR2018-002261-19-GB   Argentina;Australia;Brazil;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Serbia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
      2018   Phase 3   EUCTR2018-002261-19-BG   Argentina;Australia;Brazil;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Serbia;Spain;Taiwan;Turkey;Ukraine;United Arab Emirates;United Kingdom;United States;
   Principia Biopharma , Inc.
      2019   Phase 3   EUCTR2018-002261-19-DE   Argentina;Australia;Brazil;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
PRN1008 Freebase   
   Principia Biopharma Australia Pty Ltd
      2016   Phase 2   EUCTR2015-003564-37-HR   Australia;Croatia;France;Greece;Israel;
      2016   Phase 2   EUCTR2015-003564-37-GR   Australia;Croatia;France;Greece;Israel;
Parsaclisib   
   Incyte Corporation
      2019   Phase 2   NCT03780166   -
Prednison 10 mg GALEN   
   ARGENX BV
      2020   Phase 3   EUCTR2020-002917-16-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
Prednison 5 mg GALEN   
   ARGENX BV
      2020   Phase 3   EUCTR2020-002917-16-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
Prednison 50 mg GALEN   
   ARGENX BV
      2020   Phase 3   EUCTR2020-002917-16-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
Prednison20 mg GALEN   
   ARGENX BV
      2020   Phase 3   EUCTR2020-002917-16-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   EUCTR2020-002915-23-IT   Australia;Bulgaria;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Spain;Turkey;Ukraine;United Kingdom;United States;
Prednisone   
   CHU-Hôpitaux de Rouen
      2009   -   EUCTR2008-005266-31-FR   France;
   Institute of dermatology, Chinese Academyof Medical Sciences
      2011   -   ChiCTR-TRC-12003540   China;
      2011   -   ChiCTR-TRC-12003539   China;
   Tehran University of Medical Sciences
      2008   Phase 2   NCT00626678   Iran, Islamic Republic of;
   West China Hospital, Sichuna University
      2019   -   ChiCTR1800020382   China;
   argenx
      2021   Phase 3   NCT04598477   Australia;Bulgaria;China;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
      2020   Phase 3   NCT04598451   Australia;Bulgaria;China;France;Georgia;Germany;Greece;Hungary;India;Israel;Italy;Japan;Poland;Romania;Russian Federation;Serbia;Spain;Turkey;Ukraine;United Kingdom;United States;
Prednisone/Prednisolone   
   GlaxoSmithKline
      2015   Phase 3   NCT02613910   United States;
RO0452294/V02   
   F. Hoffmann-La Roche Ltd
      2015   Phase 3   EUCTR2014-000382-41-IT   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-FR   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-ES   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-DE   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
RO1061443/F02   
   F. Hoffmann-La Roche Ltd
      2015   Phase 3   EUCTR2014-000382-41-IT   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-FR   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-ES   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
      2015   Phase 3   EUCTR2014-000382-41-DE   Argentina;Australia;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
Recombinant human interleukin-2 (rhIL-2)   
   Second Xiangya Hospital of Central South University
      2020   Phase 2   NCT04023149   China;
Rilzabrutinib Oral Tablet   
   Principia Biopharma, a Sanofi Company
      2019   Phase 3   NCT03762265   Argentina;Australia;Brazil;Bulgaria;Canada;Croatia;France;Germany;Greece;Israel;Italy;Poland;Serbia;Spain;Taiwan;Turkey;Ukraine;United Kingdom;United States;
Rituximab   
   Department of Dermatology,Keio University School of Medicine
      2016   Phase 2   JPRN-UMIN000024265   Japan;
      2014   Phase 1,2   JPRN-UMIN000015451   Japan;
   Funakoshi Takeru
      2017   -   JPRN-jRCTs031180405   Japan;
   Hoffmann-La Roche
      2015   Phase 3   NCT02383589   Argentina;Australia;Brazil;Canada;France;Germany;Israel;Italy;Spain;Turkey;Ukraine;United States;
   ISTITUTO DERMOPATICO IMMACOLATA
      2007   -   EUCTR2007-005711-26-IT   Italy;
   Kanaoka Miwa
      2014   -   JPRN-jRCTs031180220   Japan;
   Keio University, School of Medicine
      2017   -   JPRN-UMIN000026004   Japan;
   Rabin Medical Center
      2010   -   NCT01338103   Israel;
   Research group of rare intractable dermatologial disorder
      2010   Phase 2   JPRN-UMIN000004428   Japan;
   The University of Hong Kong
      2020   Phase 2   NCT04400994   Hong Kong;
   University Hospital, Rouen
      2019   Phase 3   NCT03790293   -
      2011   Phase 3   NCT01299857   France;
      2009   Phase 3   NCT00784589   France;
   West China Hospital, Sichuna University
      2019   -   ChiCTR1800020382   China;
Rituximab (MABTHERA® or RITUXAN®).   
   University Hospital, Toulouse
      2009   -   NCT00960713   France;
Rituximab and Cyclophosphamide IV   
   Uprety Shraddha
      2013   Phase 3   NCT01974518   India;
Sirolimus (formerly known as Rapamycin)   
   University of California, Irvine
      2011   Early Phase 1   NCT01313923   United States;
TPM203   
   Topas Therapeutics GmbH
      2019   Phase 1   EUCTR2019-001727-12-DE   Germany;Israel;Italy;United Kingdom;
Tirabrutinib   
   ONO PHARMACEUTICAL CO.,LTD.
      2019   Phase 2   JPRN-JapicCTI-184231   Japan;
Triamcinolone Acetonide   
   Cairo University
      2016   Phase 3   NCT02828163   Egypt;
VAY736   
   Novartis Pharma Services AG
      2013   Phase 2   EUCTR2013-001217-33-AT   Austria;Bulgaria;Taiwan;United States;
   Novartis Pharmaceuticals
      2013   Phase 2   NCT01930175   Austria;Bulgaria;Germany;Israel;Italy;Taiwan;United Kingdom;United States;
WATER FOR INJECTION   
   Ruprecht-Karls-University Heidelberg
      2013   Phase 2   EUCTR2013-000211-24-DE   Germany;