43. 顕微鏡的多発血管炎 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 88 / 薬物数 : 81 - (DrugBank : 21) / 標的遺伝子数 : 15 - 標的パスウェイ数 : 90
薬物ごとの開発者（Primary Sponsor）、臨床試験情報（抜粋）です。
5009111000001105
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Alemtuzumab
Cambridge University Hospitals NHS Foundation Trust
2011 Phase 4 NCT01405807 United Kingdom;
Avacopan
CHEMOCENTRYX, INC.
2017 Phase 3 EUCTR2016-001121-14-IT Australia;Austria;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-SE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-DK Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-AT Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-DE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Azathioprine
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00748644 France;
2003 Phase 3 NCT00307645 France;United Kingdom;
Cambridge University Hospitals NHS Foundation Trust
2015 Phase 3 EUCTR2012-001102-14-CZ Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2013 Phase 3 NCT01697267 Australia;Canada;Czech Republic;Czechia;Ireland;Italy;Japan;New Zealand;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001102-14-ES Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
Human Genome Sciences Inc., a GSK Company
2013 Phase 3 NCT01663623 Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Norway;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Tokyo women'
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
University of Miyazaki Hospital
2014 Phase 3 JPRN-UMIN000012409 Japan,North America,South America,Australia,Europe;
s medical universityInstitute of rheumatology
Belimumab
Human Genome Sciences Inc., a GSK Company
2013 Phase 3 NCT01663623 Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Norway;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Benlysta 400 mg powder for concentrate for solution for infusion
Human Genome Sciences Inc. (a wholly owned subsidiary of GlaxoSmithKline PLC)
2013 Phase 2 EUCTR2011-004569-33-DE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Human Genome Sciences, Inc. (a wholly owned subsidiary of GlaxoSmithKline PLC)
2013 Phase 3 EUCTR2011-004569-33-SE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 3 EUCTR2011-004569-33-HU Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 3 EUCTR2011-004569-33-ES Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-PL Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-IE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-CZ Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-BE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2012 Phase 3 EUCTR2011-004569-33-GB Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Benlysta 400mg polvere per concentrato per soluzione per infusione
HUMAN GENOME SCIENCES INC
2013 - EUCTR2011-004569-33-IT Australia;Belgium;Canada;Czech Republic;European Union;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Blisibimod
Anthera Pharmaceuticals
2014 Phase 2 NCT01598857 -
CCX168
CHEMOCENTRYX, INC.
2017 Phase 3 EUCTR2016-001121-14-IT Australia;Austria;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-SE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-DK Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-AT Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-DE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
CELLCEPT
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
CellCept (mycophenolate mofetil)
Mayo Clinic
2002 Phase 1 NCT00405860 United States;
Cellcept
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Chimeric monoclonal antibody, IgG4 subtype
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-GB Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Corticosteroid and azathioprine
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00647166 France;
Cyclophosphamide
Assistance Publique - Hôpitaux de Paris
2003 Phase 3 NCT00307645 France;United Kingdom;
Cambridge University Hospitals NHS Foundation Trust
1998 Phase 2/Phase 3 NCT00430105 -
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Saitama Medical Center, Saitama Medical UniversityDepartment of Rheumatology and Clinical Immunology
2013 - JPRN-UMIN000011244 Japan;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
University Medical Centre Groningen
2004 Phase 3 NCT00103792 Netherlands;
University of Parma
2008 Phase 2 NCT00751517 Italy;
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
DELTACORTENE
AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
2010 Phase 4 EUCTR2009-013220-24-IT Czech Republic;Denmark;Italy;Poland;Spain;Sweden;United Kingdom;
ENDOXAN BAXTER
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
Freeze-Dried Sulfonated Human Normal Immunoglobulin (GGS)
TEIJIN PHARMA LIMITED
2014 Phase 3 JPRN-JapicCTI-132394 Japan;
GALEN® tablet
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Glucocorticoid (GC)
InflaRx GmbH
2019 Phase 2 NCT03895801 Belgium;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
Glucocorticoids
Chiba University
2014 Phase 4 NCT02198248 Japan;
Massachusetts General Hospital
2014 Phase 4 NCT02169219 United States;
Glucocorticoids (GC)
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Glucocorticoids - Reduced Dose
University of Pennsylvania
2010 Phase 3 NCT03919825 -
Glucocorticoids - Standard Dose
University of Pennsylvania
2010 Phase 3 NCT03919825 -
Glucocorticoids [Reduced Dose]
University of Pennsylvania
2010 Phase 3 NCT00987389 Australia;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Greece;Italy;Japan;Mexico;New Zealand;Norway;Sweden;United Kingdom;United States;
Glucocorticoids [Standard Dose]
University of Pennsylvania
2010 Phase 3 NCT00987389 Australia;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Greece;Italy;Japan;Mexico;New Zealand;Norway;Sweden;United Kingdom;United States;
Hydroxychloroquine
Guy's and St Thomas' NHS Foundation Trust
2020 Phase 4 NCT04316494 United Kingdom;
IFX-1
InflaRx GmbH
2019 Phase 2 NCT03895801 Belgium;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-GB Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2018 Phase 2 NCT03712345 Canada;United States;
Infliximab
Assistance Publique - Hôpitaux de Paris
2004 - NCT00307593 France;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
Intravenous immunoglobulins (human immunoglobulins G)
Assistance Publique - Hôpitaux de Paris
2001 Phase 3 NCT00307658 France;
Intravenous methyl prednisolone
Cambridge University Hospitals NHS Foundation Trust
1995 Phase 2/Phase 3 NCT01408836 United Kingdom;
MabThera
Cambridge University Hospitals NHS Foundation Trust
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2013 - EUCTR2012-001102-14-ES Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
MabThera®
Cambridge University Hospitals NHS Foundation Trust
2015 Phase 3 EUCTR2012-001102-14-CZ Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
F. HOFFMANN - LA ROCHE LTD.
2013 - EUCTR2012-002062-13-IT Italy;Turkey;United Kingdom;United States;
F. Hoffmann-La Roche Ltd.
2013 Phase 2 EUCTR2012-002062-13-GB Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
2013 Phase 2 EUCTR2012-002062-13-DE Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
Methotrexate
Cambridge University Hospitals NHS Foundation Trust
2015 Phase 3 EUCTR2012-001102-14-CZ Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University of Parma
2008 Phase 2 NCT00751517 Italy;
Methylprednisolone
Hoffmann-La Roche
2015 Phase 4 NCT02115997 India;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
Methylprednisolone (or other glucocorticoid)
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Mycophenolate
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Mycophenolate mofetil
Assistance Publique - Hôpitaux de Paris
2003 Phase 3 NCT00307645 France;United Kingdom;
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
University Medical Centre Groningen
2004 Phase 3 NCT00103792 Netherlands;
Mycophenolate mofetil,methotrexate
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Mycophenolic acid
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
Naltrexone Hydrochloride
University of Pennsylvania
2019 Phase 2 NCT03482479 United States;
Pednisone
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Placebo (physiological saline)
TEIJIN PHARMA LIMITED
2014 Phase 3 JPRN-JapicCTI-132394 Japan;
Plaquenil - Hydroxychloroquine 200mg Film coated tablets
Guy's and St. Thomas' NHS Foundation Trust
2020 Phase 4 EUCTR2018-001268-40-GB United Kingdom;
Plasma Exchange
University of Pennsylvania
2010 Phase 3 NCT00987389 Australia;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Greece;Italy;Japan;Mexico;New Zealand;Norway;Sweden;United Kingdom;United States;
Plasma exchange
Cambridge University Hospitals NHS Foundation Trust
1995 Phase 2/Phase 3 NCT01408836 United Kingdom;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
PredniSONE Tablets, USP
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-GB Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Prednisolone
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
Prednison acis®
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-SE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-DK Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-AT Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-DE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Prednison acis¿
CHEMOCENTRYX, INC.
2017 Phase 3 EUCTR2016-001121-14-IT Australia;Austria;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Prednisone
AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
2010 Phase 4 EUCTR2009-013220-24-IT Czech Republic;Denmark;Italy;Poland;Spain;Sweden;United Kingdom;
Hoffmann-La Roche
2015 Phase 4 NCT02115997 India;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Prednisone (and methylprednisolone)
Assistance Publique - Hôpitaux de Paris
2003 Phase 3 NCT00307645 France;United Kingdom;
Prednisone, methylprednisolone,cyclophosphamides
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
RO0452294/V01
F. Hoffmann-La Roche Ltd.
2013 Phase 2 EUCTR2012-002062-13-GB Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
2013 Phase 2 EUCTR2012-002062-13-DE Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
RO0452294/V02
F. Hoffmann-La Roche Ltd.
2013 Phase 2 EUCTR2012-002062-13-GB Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
2013 Phase 2 EUCTR2012-002062-13-DE Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
Remission induction therapy
Masayoshi Harigai
2018 Phase 2 JPRN-JMA-IIA00325 Japan;
Rituximab
Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust
2006 Phase 3 EUCTR2005-003610-15-CZ Czech Republic;Sweden;United Kingdom;
Assistance Publique - Hôpitaux de Paris
2020 Phase 3 NCT03920722 France;
2008 Phase 3 NCT00748644 France;
2004 - NCT00307593 France;
CHU de Saint-Etienne
2015 Phase 4 EUCTR2015-001807-29-FR France;
Cambridge University Hospitals NHS Foundation Trust
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2013 Phase 3 NCT01697267 Australia;Canada;Czech Republic;Czechia;Ireland;Italy;Japan;New Zealand;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001102-14-ES Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Chiba University
2014 Phase 4 NCT02198248 Japan;
Genentech, Inc.
2012 - NCT01613599 United States;
Hoffmann-La Roche
2015 Phase 4 NCT02115997 India;
2013 Phase 2 NCT01750697 Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
Massachusetts General Hospital
2014 Phase 4 NCT02169219 United States;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University of Miyazaki Hospital
2014 Phase 3 JPRN-UMIN000012409 Japan,North America,South America,Australia,Europe;
Rituximab (Arm A)
Assistance Publique - Hôpitaux de Paris
2012 Phase 3 NCT01731561 France;
Rituximab (Arm B)
Assistance Publique - Hôpitaux de Paris
2012 Phase 3 NCT01731561 France;
Ro106-1443
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Sendoxan
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Tocilizumab
Clinical Immunology Saitama Medical Center, Saitama Medical Universitity
Department of Rheumatology &
Saitama Medical Center, Saitama Medical UniversityDepartment of Rheumatology and Clinical Immunology
2013 - JPRN-UMIN000011244 Japan;
2013 - JPRN-UMIN000011242 Japan;
Vilobelimab
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Vitamin D
Christian Pagnoux
2020 - NCT04280601 Canada;
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Alemtuzumab
Cambridge University Hospitals NHS Foundation Trust
2011 Phase 4 NCT01405807 United Kingdom;
Avacopan
CHEMOCENTRYX, INC.
2017 Phase 3 EUCTR2016-001121-14-IT Australia;Austria;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-SE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-DK Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-AT Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-DE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Azathioprine
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00748644 France;
2003 Phase 3 NCT00307645 France;United Kingdom;
Cambridge University Hospitals NHS Foundation Trust
2015 Phase 3 EUCTR2012-001102-14-CZ Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2013 Phase 3 NCT01697267 Australia;Canada;Czech Republic;Czechia;Ireland;Italy;Japan;New Zealand;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001102-14-ES Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
Human Genome Sciences Inc., a GSK Company
2013 Phase 3 NCT01663623 Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Norway;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Tokyo women'
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
University of Miyazaki Hospital
2014 Phase 3 JPRN-UMIN000012409 Japan,North America,South America,Australia,Europe;
s medical universityInstitute of rheumatology
Belimumab
Human Genome Sciences Inc., a GSK Company
2013 Phase 3 NCT01663623 Australia;Austria;Belgium;Brazil;Canada;Czech Republic;Czechia;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Norway;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Benlysta 400 mg powder for concentrate for solution for infusion
Human Genome Sciences Inc. (a wholly owned subsidiary of GlaxoSmithKline PLC)
2013 Phase 2 EUCTR2011-004569-33-DE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Human Genome Sciences, Inc. (a wholly owned subsidiary of GlaxoSmithKline PLC)
2013 Phase 3 EUCTR2011-004569-33-SE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 3 EUCTR2011-004569-33-HU Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 3 EUCTR2011-004569-33-ES Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-PL Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-IE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-CZ Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2013 Phase 2 EUCTR2011-004569-33-BE Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
2012 Phase 3 EUCTR2011-004569-33-GB Australia;Austria;Belgium;Canada;Czech Republic;Finland;France;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Romania;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Benlysta 400mg polvere per concentrato per soluzione per infusione
HUMAN GENOME SCIENCES INC
2013 - EUCTR2011-004569-33-IT Australia;Belgium;Canada;Czech Republic;European Union;Germany;Hungary;India;Ireland;Italy;Mexico;Peru;Poland;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;United States;
Blisibimod
Anthera Pharmaceuticals
2014 Phase 2 NCT01598857 -
CCX168
CHEMOCENTRYX, INC.
2017 Phase 3 EUCTR2016-001121-14-IT Australia;Austria;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-SE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-DK Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-AT Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-DE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
CELLCEPT
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
CellCept (mycophenolate mofetil)
Mayo Clinic
2002 Phase 1 NCT00405860 United States;
Cellcept
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Chimeric monoclonal antibody, IgG4 subtype
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-GB Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Corticosteroid and azathioprine
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00647166 France;
Cyclophosphamide
Assistance Publique - Hôpitaux de Paris
2003 Phase 3 NCT00307645 France;United Kingdom;
Cambridge University Hospitals NHS Foundation Trust
1998 Phase 2/Phase 3 NCT00430105 -
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Saitama Medical Center, Saitama Medical UniversityDepartment of Rheumatology and Clinical Immunology
2013 - JPRN-UMIN000011244 Japan;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
University Medical Centre Groningen
2004 Phase 3 NCT00103792 Netherlands;
University of Parma
2008 Phase 2 NCT00751517 Italy;
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
DELTACORTENE
AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
2010 Phase 4 EUCTR2009-013220-24-IT Czech Republic;Denmark;Italy;Poland;Spain;Sweden;United Kingdom;
ENDOXAN BAXTER
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
Freeze-Dried Sulfonated Human Normal Immunoglobulin (GGS)
TEIJIN PHARMA LIMITED
2014 Phase 3 JPRN-JapicCTI-132394 Japan;
GALEN® tablet
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Glucocorticoid (GC)
InflaRx GmbH
2019 Phase 2 NCT03895801 Belgium;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
Glucocorticoids
Chiba University
2014 Phase 4 NCT02198248 Japan;
Massachusetts General Hospital
2014 Phase 4 NCT02169219 United States;
Glucocorticoids (GC)
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Glucocorticoids - Reduced Dose
University of Pennsylvania
2010 Phase 3 NCT03919825 -
Glucocorticoids - Standard Dose
University of Pennsylvania
2010 Phase 3 NCT03919825 -
Glucocorticoids [Reduced Dose]
University of Pennsylvania
2010 Phase 3 NCT00987389 Australia;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Greece;Italy;Japan;Mexico;New Zealand;Norway;Sweden;United Kingdom;United States;
Glucocorticoids [Standard Dose]
University of Pennsylvania
2010 Phase 3 NCT00987389 Australia;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Greece;Italy;Japan;Mexico;New Zealand;Norway;Sweden;United Kingdom;United States;
Hydroxychloroquine
Guy's and St Thomas' NHS Foundation Trust
2020 Phase 4 NCT04316494 United Kingdom;
IFX-1
InflaRx GmbH
2019 Phase 2 NCT03895801 Belgium;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-GB Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2018 Phase 2 NCT03712345 Canada;United States;
Infliximab
Assistance Publique - Hôpitaux de Paris
2004 - NCT00307593 France;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
Intravenous immunoglobulins (human immunoglobulins G)
Assistance Publique - Hôpitaux de Paris
2001 Phase 3 NCT00307658 France;
Intravenous methyl prednisolone
Cambridge University Hospitals NHS Foundation Trust
1995 Phase 2/Phase 3 NCT01408836 United Kingdom;
MabThera
Cambridge University Hospitals NHS Foundation Trust
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2013 - EUCTR2012-001102-14-ES Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
MabThera®
Cambridge University Hospitals NHS Foundation Trust
2015 Phase 3 EUCTR2012-001102-14-CZ Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
F. HOFFMANN - LA ROCHE LTD.
2013 - EUCTR2012-002062-13-IT Italy;Turkey;United Kingdom;United States;
F. Hoffmann-La Roche Ltd.
2013 Phase 2 EUCTR2012-002062-13-GB Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
2013 Phase 2 EUCTR2012-002062-13-DE Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
Methotrexate
Cambridge University Hospitals NHS Foundation Trust
2015 Phase 3 EUCTR2012-001102-14-CZ Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University of Parma
2008 Phase 2 NCT00751517 Italy;
Methylprednisolone
Hoffmann-La Roche
2015 Phase 4 NCT02115997 India;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
Methylprednisolone (or other glucocorticoid)
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Mycophenolate
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Mycophenolate mofetil
Assistance Publique - Hôpitaux de Paris
2003 Phase 3 NCT00307645 France;United Kingdom;
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
University Medical Centre Groningen
2004 Phase 3 NCT00103792 Netherlands;
Mycophenolate mofetil,methotrexate
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Mycophenolic acid
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Vasculitis and Lupus Clinic
2008 - EUCTR2006-001663-33-IT Austria;France;Germany;Italy;Spain;Sweden;United Kingdom;
Naltrexone Hydrochloride
University of Pennsylvania
2019 Phase 2 NCT03482479 United States;
Pednisone
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Placebo (physiological saline)
TEIJIN PHARMA LIMITED
2014 Phase 3 JPRN-JapicCTI-132394 Japan;
Plaquenil - Hydroxychloroquine 200mg Film coated tablets
Guy's and St. Thomas' NHS Foundation Trust
2020 Phase 4 EUCTR2018-001268-40-GB United Kingdom;
Plasma Exchange
University of Pennsylvania
2010 Phase 3 NCT00987389 Australia;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Greece;Italy;Japan;Mexico;New Zealand;Norway;Sweden;United Kingdom;United States;
Plasma exchange
Cambridge University Hospitals NHS Foundation Trust
1995 Phase 2/Phase 3 NCT01408836 United Kingdom;
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
PredniSONE Tablets, USP
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-IT Belgium;Czech Republic;Czechia;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-GB Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-ES Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DK Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-BE Belgium;Czech Republic;Denmark;France;Germany;Ireland;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Prednisolone
University Hospital Birmingham NHS Foundation Trust
2003 Phase 2 NCT00753103 United Kingdom;
Prednison acis®
ChemoCentryx, Inc.
2017 Phase 3 EUCTR2016-001121-14-SE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NO Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-NL Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-HU Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-GB Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-ES Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-DK Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-CZ Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-BE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
2017 Phase 3 EUCTR2016-001121-14-AT Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-IE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-FR Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
- Phase 3 EUCTR2016-001121-14-DE Australia;Austria;Belgium;Canada;Czech Republic;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Prednison acis¿
CHEMOCENTRYX, INC.
2017 Phase 3 EUCTR2016-001121-14-IT Australia;Austria;Belgium;Canada;Czech Republic;Czechia;Denmark;France;Germany;Hungary;Ireland;Italy;Netherlands;New Zealand;Norway;Spain;Sweden;Switzerland;United Kingdom;United States;
Prednisone
AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
2010 Phase 4 EUCTR2009-013220-24-IT Czech Republic;Denmark;Italy;Poland;Spain;Sweden;United Kingdom;
Hoffmann-La Roche
2015 Phase 4 NCT02115997 India;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
Prednisone (and methylprednisolone)
Assistance Publique - Hôpitaux de Paris
2003 Phase 3 NCT00307645 France;United Kingdom;
Prednisone, methylprednisolone,cyclophosphamides
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
RO0452294/V01
F. Hoffmann-La Roche Ltd.
2013 Phase 2 EUCTR2012-002062-13-GB Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
2013 Phase 2 EUCTR2012-002062-13-DE Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
RO0452294/V02
F. Hoffmann-La Roche Ltd.
2013 Phase 2 EUCTR2012-002062-13-GB Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
2013 Phase 2 EUCTR2012-002062-13-DE Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
Remission induction therapy
Masayoshi Harigai
2018 Phase 2 JPRN-JMA-IIA00325 Japan;
Rituximab
Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust
2006 Phase 3 EUCTR2005-003610-15-CZ Czech Republic;Sweden;United Kingdom;
Assistance Publique - Hôpitaux de Paris
2020 Phase 3 NCT03920722 France;
2008 Phase 3 NCT00748644 France;
2004 - NCT00307593 France;
CHU de Saint-Etienne
2015 Phase 4 EUCTR2015-001807-29-FR France;
Cambridge University Hospitals NHS Foundation Trust
2014 Phase 3 EUCTR2012-001102-14-IT Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
2013 Phase 3 NCT01697267 Australia;Canada;Czech Republic;Czechia;Ireland;Italy;Japan;New Zealand;Sweden;United Kingdom;United States;
2013 - EUCTR2012-001102-14-ES Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
- Phase 3 EUCTR2012-001102-14-GB Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
Chiba University
2014 Phase 4 NCT02198248 Japan;
Genentech, Inc.
2012 - NCT01613599 United States;
Hoffmann-La Roche
2015 Phase 4 NCT02115997 India;
2013 Phase 2 NCT01750697 Canada;France;Germany;Italy;Serbia;Turkey;United Kingdom;United States;
Massachusetts General Hospital
2014 Phase 4 NCT02169219 United States;
National Institute of Allergy and Infectious Diseases (NIAID)
2005 Phase 2/Phase 3 NCT00104299 Netherlands;United States;
University College Cork , Ireland
2014 Phase 3 EUCTR2012-001102-14-IE Australia;Austria;Canada;Czech Republic;Denmark;Germany;Ireland;Italy;Japan;Mexico;Netherlands;New Zealand;Poland;Spain;Sweden;Switzerland;United Kingdom;
University of Miyazaki Hospital
2014 Phase 3 JPRN-UMIN000012409 Japan,North America,South America,Australia,Europe;
Rituximab (Arm A)
Assistance Publique - Hôpitaux de Paris
2012 Phase 3 NCT01731561 France;
Rituximab (Arm B)
Assistance Publique - Hôpitaux de Paris
2012 Phase 3 NCT01731561 France;
Ro106-1443
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Sendoxan
Cambridge University Hospitals NHS Foundation Trust
2008 Phase 2 EUCTR2006-001663-33-SE Austria;Czech Republic;France;Germany;Italy;Spain;Sweden;United Kingdom;
Tocilizumab
Clinical Immunology Saitama Medical Center, Saitama Medical Universitity
Department of Rheumatology &
Saitama Medical Center, Saitama Medical UniversityDepartment of Rheumatology and Clinical Immunology
2013 - JPRN-UMIN000011244 Japan;
2013 - JPRN-UMIN000011242 Japan;
Vilobelimab
InflaRx GmbH
2019 Phase 2 EUCTR2018-000768-27-SE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;Switzerland;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-NL Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-DE Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
2019 Phase 2 EUCTR2018-000768-27-CZ Belgium;Czech Republic;Czechia;Denmark;France;Germany;Italy;Netherlands;Russian Federation;Spain;Sweden;United Kingdom;
Vitamin D
Christian Pagnoux
2020 - NCT04280601 Canada;