75. クッシング病 Disease details / Clinical trials / Drug dev / DR info


臨床試験数 : 205 / 薬物数 : 176 - (DrugBank : 45) / 標的遺伝子数 : 61 - 標的パスウェイ数 : 127

薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
(R)-(1-(4-FLUOROPHENYL)-6-((1-METHYL-1H-PYRAZOL-4-   
   CORCEPT THERAPEUTICS
      2019   Phase 3   EUCTR2018-003096-35-IT   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
(R)-(1-(4-FLUOROPHENYL)-6-((1-METHYL-1H-PYRAZOL-4-YL)SULFONYL)-4,4A,5,6,7,8-HEXAHYDRO-1H-PYRAZOLO[3,4-G]ISOQUINOLIN-4A-YL)(4-(TRIFLUOROMETHYL)PYRIDIN-2-YL)METHANONE   
   Corcept Therapeutics Incorporated
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-ES   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-DE   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-BG   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 2   EUCTR2018-001616-30-HU   Hungary;Italy;United States;
(R)-(1-(4-FLUOROPHENYL)-6-((1-METHYL-1H-PYRAZOL-4-YL)SULFONYL)4,4A,5,6,7,8-HEXAHYDRO-1H-PYRAZOLO[3,4-G]ISOQUINOLIN-4A-YL)(4(TRIFLUOROMETHYL)PYRIDIN-2-YL)METHANONE   
   Corcept Therapeutics Incorporated
      2019   Phase 3   EUCTR2018-003096-35-PL   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-NL   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-ES   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-DE   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-BG   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-AT   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
17beta-hydroxy-11beta-(4-dimethylaminophenyl)17a-(prop-1-ynyl)estra-4,9-dien-3-one   
   Laboratoire HRA Pharma
      2007   -   EUCTR2006-004679-36-NL   France;Germany;Italy;Netherlands;
      2007   -   EUCTR2006-004679-36-DE   France;Germany;Italy;Netherlands;United States;
      2006   -   EUCTR2006-004679-36-FR   France;Germany;Italy;Netherlands;
17ß-hydroxy-11ß-(4-dimethylaminophenyl)17a-(prop-1-ynyl)estra-4,9-dien-3-one   
   Laboratoire HRA Pharma
      2007   -   EUCTR2006-004679-36-NL   France;Germany;Italy;Netherlands;
      2007   -   EUCTR2006-004679-36-DE   France;Germany;Italy;Netherlands;United States;
      2006   -   EUCTR2006-004679-36-FR   France;Germany;Italy;Netherlands;
18F-DOPA   
   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
      2014   Phase 2   NCT02019706   United States;
      1999   Phase 1/Phase 2   NCT00001849   United States;
2S,4R-(-)-ketoconazole   
   Cortendo AB
      2016   Phase 3   EUCTR2013-002133-37-CZ   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Serbia;Spain;Sweden;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-IT   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Spain;Sweden;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-ES   Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Serbia;Spain;Sweden;United Kingdom;United States;
2S,4R-(-)-ketoconazole, levoketoconazole   
   Cortendo AB
      2016   Phase 3   EUCTR2013-002133-37-HU   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2015   Phase 3   EUCTR2013-002133-37-DK   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Turkey;United Kingdom;United States;
      2015   Phase 3   EUCTR2013-002133-37-DE   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2015   Phase 3   EUCTR2013-002133-37-BG   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-SE   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;United Kingdom;
      2014   Phase 3   EUCTR2013-002133-37-NL   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-GB   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-BE   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
68Ga-DOTATATE   
   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
      2014   Phase 2   NCT02019706   United States;
ATR-101   
   Millendo Therapeutics US, Inc.
      2017   Phase 2   NCT03053271   United Kingdom;United States;
   Millendo Therapeutics, Inc.
      2017   Phase 2   EUCTR2016-002240-17-GB   United Kingdom;United States;
AZD4017   
   University of Oxford, Clinical Trials and Research Governance
      2017   Phase 2   EUCTR2016-003060-40-GB   United Kingdom;
AZD4017 and prednisolone   
   University of Oxford
      2017   Phase 2   NCT03111810   United Kingdom;
Abiraterone Acetate   
   Azienda Ospedaliera Spedali Civili di Brescia
      2017   Phase 2   NCT03145285   Italy;
Abiraterone acetato   
   AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA
      2016   Phase 2   EUCTR2016-000945-29-IT   Italy;
Acthrel   
   National Institute of Neurological Disorders and Stroke (NINDS)
      2022   -   NCT04569591   United States;
      2011   Early Phase 1   NCT01459237   United States;
Alprazolam   
   Asari Yuko
      2021   Phase 2   JPRN-jRCT1021210011   Japan;
Bexarotene   
   University of Virginia
      2008   Phase 1/Phase 2   NCT00845351   United States;
CABERGOLINE TEVA   
   Novartis Pharma Services AG
      2013   Phase 2   EUCTR2013-002170-49-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
CI-984   
   Millendo Therapeutics, Inc.
      2017   Phase 2   EUCTR2016-002240-17-GB   United Kingdom;United States;
CIALIS - 20 MG 2 COMPRESSE RIVESTITE CON FILM IN BLISTER USO ORALE   
   UMBERTO I - POLICLINICO DI ROMA
      2016   Phase 2   EUCTR2015-004497-15-IT   Italy;
COR-003   
   CORTENDO AB
      2018   Phase 3   EUCTR2017-001219-35-IT   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
   Cortendo AB
      2019   Phase 3   EUCTR2017-004647-20-NL   Bulgaria;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2017-004647-20-IT   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2019   Phase 3   EUCTR2017-004647-20-GR   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2017-004647-20-ES   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2019   Phase 3   EUCTR2017-004647-20-BG   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-004647-20-HU   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2018   Phase 3   EUCTR2017-001219-35-PL   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-NL   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-HU   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-GR   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-FR   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-ES   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-DK   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-BG   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2016   Phase 3   EUCTR2013-002133-37-HU   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2016   Phase 3   EUCTR2013-002133-37-CZ   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Serbia;Spain;Sweden;Turkey;United Kingdom;United States;
      2015   Phase 3   EUCTR2013-002133-37-DK   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Turkey;United Kingdom;United States;
      2015   Phase 3   EUCTR2013-002133-37-DE   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2015   Phase 3   EUCTR2013-002133-37-BG   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-SE   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;United Kingdom;
      2014   Phase 3   EUCTR2013-002133-37-NL   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-IT   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Spain;Sweden;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-GB   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-ES   Austria;Belgium;Brazil;Bulgaria;Canada;China;Czech Republic;Denmark;Germany;Hungary;Israel;Italy;Mexico;Netherlands;Serbia;Spain;Sweden;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-002133-37-BE   Belgium;Bulgaria;Canada;Czech Republic;Denmark;France;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
CORT125134   
   CORCEPT THERAPEUTICS
      2019   Phase 3   EUCTR2018-003096-35-IT   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 2   EUCTR2018-001616-30-IT   Bulgaria;Germany;Hungary;Italy;Spain;United States;
      2016   Phase 2   EUCTR2016-000899-23-IT   Hungary;Italy;Netherlands;United Kingdom;
   Corcept Therapeutics
      2016   Phase 2   NCT02804750   Hungary;Italy;Netherlands;United Kingdom;United States;
   Corcept Therapeutics Incorporated
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-ES   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-DE   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-BG   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-PL   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-NL   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-ES   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-DE   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-BG   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-AT   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 2   EUCTR2018-001616-30-HU   Hungary;Italy;United States;
      2016   Phase 2   EUCTR2016-000899-23-NL   Hungary;Netherlands;United Kingdom;United States;
      2016   Phase 2   EUCTR2016-000899-23-HU   Hungary;Netherlands;United Kingdom;United States;
      2016   Phase 2   EUCTR2016-000899-23-GB   Hungary;Netherlands;United Kingdom;United States;
Cabergoline   
   Erasmus MC
      2011   -   EUCTR2011-003264-77-NL   Netherlands;
   NOVARTIS FARMA S.p.A.
      2014   Phase 2   EUCTR2013-002170-49-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   RECORDATI GROUP
      2013   Phase 4   NCT01794793   Argentina;Belgium;Brazil;Bulgaria;Canada;China;France;Germany;Greece;Hungary;India;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Spain;Switzerland;Taiwan;Thailand;Turkey;United States;
   Seth Gordhandas Sunderdas Medical College
      2007   Phase 3   NCT00889525   India;
   Swedish Pituitary Study group
      2010   -   EUCTR2010-018720-12-SE   Sweden;
Calcium carbonate   
   Pierre Fabre Médicament
      2008   Phase 3   EUCTR2008-002280-14-FR   France;
Cholecalciferol 15000 UNT/ML Oral Solution   
   Endocrinology Research Centre, Moscow
      2019   Phase 1   NCT04844164   Russian Federation;
Continuous glucose monitoring   
   Huashan Hospital
      2014   -   NCT02574793   China;
Cushing's syndrome confirmation   
   Corcept Therapeutics
      2009   -   NCT00796783   United States;
Cyclo ((diaminoethyl-carbamate)HyPro-Phg-(D) Trp-Ly di-aspartate   
   Novartis Pharma Services AG
      2007   -   EUCTR2006-004111-22-FR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
Cyclo ((diaminoethyl-carbamate)HyPro-Phg-(D)Trp-Ly di-aspartate   
   Novartis Pharma Services AG
      2007   -   EUCTR2006-004111-22-FR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
Cyclo((diaminoethyl-carbamate)HyPro-Phg-(D)Trp-Lys-Tyr(Bzl)-Phe) di-aspartate   
   Novartis Farmaceútica S.A.
      2007   -   EUCTR2006-004111-22-ES   Argentina;Belgium;Brazil;Canada;China;Denmark;Finland;France;Germany;Greece;Hungary;Israel;Italy;Mexico;Poland;Portugal;Spain;Turkey;United Kingdom;United States;
   Novartis Pharma Services AG
      2008   Phase 3   EUCTR2006-004111-22-GB   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2008   -   EUCTR2006-004111-22-HU   Belgium;Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   Phase 3   EUCTR2006-004111-22-BE   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-PT   Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-GR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-FR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-FI   Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-DK   Belgium;Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-DE   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
Cyclo(diaminoethyl-carbamate)HyPro-Phg-(D)Trp-Lys-Tyr(Bzl)-Phe)   
   Novartis Pharmaceuticals UK Ltd
      2005   -   EUCTR2004-002407-32-GB   Italy;United Kingdom;
DDAVP   
   Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine
      2015   -   JPRN-UMIN000018891   Japan;
   Kageyama Kazunori
      2018   Phase 3   JPRN-jRCTs021180039   Japan;
Dexamethasone   
   Centre Hospitalier Universitaire de Nimes
      2019   -   NCT03974789   France;
Dostinex   
   Dipartimento di Medicina-DIMED, università di Padova
      2021   Phase 2   EUCTR2019-004019-29-IT   Italy;
   Erasmus MC
      2007   -   EUCTR2006-004080-55-NL   Netherlands;
   NOVARTIS FARMA S.p.A.
      2014   Phase 2   EUCTR2013-002170-49-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   Novartis Farmacéutica , S.A.
      2013   Phase 2   EUCTR2013-002170-49-ES   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   Novartis Pharma Services AG
      2015   Phase 2   EUCTR2013-002170-49-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-GR   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2013   Phase 2   EUCTR2013-002170-49-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
Eplerenone   
   Hiroshima University HospitalDepartment of Endocrinology and Diabetes mellitus
      2009   -   JPRN-UMIN000002925   Japan;
G02CB03   
   Dipartimento di Medicina-DIMED, università di Padova
      2021   Phase 2   EUCTR2019-004019-29-IT   Italy;
Gefitinib   
   Huashan Hospital
      2015   Phase 2   NCT02484755   China;
Genotropin Miniqu   
   Amar Agha, Beaumont Hospital
      2009   -   EUCTR2009-010918-30-IE   Ireland;
Genotropin Miniquick   
   Amar Agha, Beaumont Hospital
      2009   -   EUCTR2009-010918-30-IE   Ireland;
Glucocorticoids   
   University of Leeds
      1998   -   NCT03575247   -
Glucophage (metformin)   
   Queen Mary University of London
      2010   Phase 2   EUCTR2008-005708-18-GB   United Kingdom;
HRA052015   
   LABORATOIRE HRA PHARMA
      2007   -   EUCTR2006-004679-36-IT   France;Germany;Italy;Netherlands;
   Laboratoire HRA Pharma
      2007   -   EUCTR2006-004679-36-NL   France;Germany;Italy;Netherlands;
      2007   -   EUCTR2006-004679-36-DE   France;Germany;Italy;Netherlands;United States;
      2006   -   EUCTR2006-004679-36-FR   France;Germany;Italy;Netherlands;
HRA052015 (mifepristone)   
   Sheffield Teaching Hospitals NHS Foundation Trust
      2009   Phase 2   EUCTR2007-007604-15-GB   United Kingdom;
Hydrocortisone   
   Tianjin Medical University General Hospital
      2014   -   JPRN-UMIN000041513   Asia(except Japan);
   University Hospital, Bordeaux
      2012   -   NCT02889224   France;
Hypercortisolism   
   University Hospital, Bordeaux
      2012   -   NCT02889224   France;
IPC   
   Huashan Hospital
      2020   -   NCT04486859   China;
Insulin   
   Novartis Pharmaceuticals
      2014   Phase 4   NCT02060383   Belgium;Brazil;China;Denmark;Germany;India;Peru;Poland;Russian Federation;Thailand;Turkey;United States;
Ketoconazole   
   Erasmus MC
      2011   -   EUCTR2011-003264-77-NL   Netherlands;
L0006CP03A   
   Pierre Fabre Médicament
      2008   Phase 3   EUCTR2008-002280-14-FR   France;
L01XX14   
   Dipartimento di Medicina-DIMED, università di Padova
      2021   Phase 2   EUCTR2019-004019-29-IT   Italy;
LCI699   
   NOVARTIS FARMA
      2011   Phase 2   EUCTR2010-022403-22-IT   Italy;United States;
   NOVARTIS FARMA S.p.A.
      2014   Phase 3   EUCTR2013-004766-34-IT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Slovakia;Spain;Taiwan;Thailand;Turkey;United Kingdom;United States;
   NOVARTIS PHARMA AG
      2018   Phase 2   EUCTR2017-002840-34-IT   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
   Novartis Farmacéutica, S.A
      2018   Phase 2   EUCTR2017-002840-34-ES   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
   Novartis Farmacéutica, S.A.
      2019   Phase 2   EUCTR2018-001522-25-ES   Belgium;Bulgaria;Italy;Slovenia;Spain;United Kingdom;United States;
      2016   Phase 3   EUCTR2014-004092-23-ES   Belgium;Brazil;Denmark;Greece;Poland;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2014   Phase 3   EUCTR2013-004766-34-ES   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Slovakia;Spain;Taiwan;Thailand;Turkey;United Kingdom;United States;
   Novartis Pharma AG
      2020   Phase 2   EUCTR2018-001522-25-IT   Belgium;Bulgaria;Italy;Slovenia;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-001522-25-BE   Belgium;Bulgaria;Italy;Slovenia;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2017-002840-34-FR   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
      2019   Phase 2   EUCTR2017-002840-34-BE   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
   Novartis Pharma Services AG
      2016   Phase 3   EUCTR2014-004092-23-PT   Belgium;Brazil;Canada;China;Costa Rica;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2016   Phase 3   EUCTR2014-004092-23-PL   Belgium;Brazil;Canada;China;Costa Rica;Denmark;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2016   Phase 3   EUCTR2014-004092-23-GR   Belgium;Brazil;Denmark;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2016   Phase 3   EUCTR2014-004092-23-BE   Belgium;Brazil;Canada;China;Costa Rica;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2015   Phase 3   EUCTR2013-004766-34-NL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-004766-34-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-004766-34-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-004766-34-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
   Novartis Pharmaceuticals
      2020   Phase 2   NCT03708900   Belgium;Bulgaria;Italy;Slovenia;United Kingdom;
      2011   Phase 2   NCT01331239   France;Italy;Japan;United States;
   Recordati AG
      2019   Phase 2   EUCTR2018-001522-25-SI   Belgium;Bulgaria;Italy;Slovenia;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-001522-25-GB   Belgium;Bulgaria;Italy;Slovenia;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-001522-25-BG   Belgium;Bulgaria;Italy;Slovenia;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2017-002840-34-NL   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
      2019   Phase 2   EUCTR2017-002840-34-BG   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
      2018   Phase 2   EUCTR2017-002840-34-DE   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
      2018   Phase 2   EUCTR2017-002840-34-AT   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
      -   Phase 2   EUCTR2017-002840-34-PL   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
LCI699,   
   Novartis Pharma Services AG
      2014   Phase 3   EUCTR2013-004766-34-DE   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
LMWH/Rivaroxaban   
   Huashan Hospital
      2020   -   NCT04486859   China;
Lapatinib   
   Peking Union Medical College Hospital
      2017   -   ChiCTR-OPC-17011664   China;
Lateral transperitoneal LA   
   Jagiellonian University
      2006   Phase 4   NCT01959711   Poland;
Levoketoconazole   
   CORTENDO AB
      2018   Phase 3   EUCTR2017-001219-35-IT   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
   Cortendo AB
      2019   Phase 3   NCT03621280   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2019   Phase 3   EUCTR2017-004647-20-NL   Bulgaria;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2017-004647-20-IT   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2019   Phase 3   EUCTR2017-004647-20-GR   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2017-004647-20-ES   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2019   Phase 3   EUCTR2017-004647-20-BG   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-004647-20-HU   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2018   Phase 3   EUCTR2017-001219-35-PL   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-NL   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-HU   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-GR   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-FR   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-ES   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-DK   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-BG   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2017   Phase 3   NCT03277690   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2014   Phase 3   NCT01838551   Belgium;Bulgaria;Canada;Czech Republic;Czechia;Denmark;France;Georgia;Germany;Hungary;Israel;Italy;Netherlands;Poland;Serbia;Spain;Sweden;Switzerland;Turkey;United Kingdom;United States;
Levoketozonazole   
   CORTENDO AB
      2018   Phase 3   EUCTR2017-001219-35-IT   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
   Cortendo AB
      2019   Phase 3   EUCTR2017-004647-20-NL   Bulgaria;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2017-004647-20-IT   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2019   Phase 3   EUCTR2017-004647-20-GR   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2017-004647-20-ES   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2019   Phase 3   EUCTR2017-004647-20-BG   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-004647-20-HU   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;Turkey;United States;
      2018   Phase 3   EUCTR2017-001219-35-PL   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-NL   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-HU   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-GR   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-FR   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-ES   Bulgaria;Canada;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-DK   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 3   EUCTR2017-001219-35-BG   Bulgaria;Denmark;France;Greece;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
Liqourice   
   Umeå University
      2018   -   NCT04045015   Sweden;
Liraglutide   
   Novartis Pharmaceuticals
      2014   Phase 4   NCT02060383   Belgium;Brazil;China;Denmark;Germany;India;Peru;Poland;Russian Federation;Thailand;Turkey;United States;
Matyrapone   
   S.C.D.U. MEDICINA INTERNA 1 Ospedale San Luigi Orbassano
      2013   -   EUCTR2013-002063-26-IT   Italy;
Metformin   
   Barts & The London NHS Trust
      2012   Phase 2/Phase 3   NCT01319994   United Kingdom;
   Novartis Pharmaceuticals
      2014   Phase 4   NCT02060383   Belgium;Brazil;China;Denmark;Germany;India;Peru;Poland;Russian Federation;Thailand;Turkey;United States;
Methionine   
   Hospices Civils de Lyon
      2017   -   NCT03346954   France;
Metopirone 250 mg capsules   
   Laboratoire HRA Pharma
      2016   Phase 4   EUCTR2014-000162-22-PL   Belgium;Germany;Hungary;Italy;Poland;Romania;Spain;Turkey;
      2015   Phase 4   EUCTR2014-000162-22-DE   Belgium;Germany;Hungary;Italy;Poland;Romania;Spain;Turkey;
      2015   Phase 4   EUCTR2014-000162-22-BE   Belgium;Germany;Hungary;Italy;Poland;Spain;Sweden;Switzerland;United States;
      2015   Phase 3   EUCTR2014-000162-22-ES   Belgium;Germany;Hungary;Italy;Poland;Spain;Sweden;Switzerland;United States;
Metopirone 250 mg capsules/ Cormeto   
   Laboratoire HRA Pharma
      2018   Phase 3   EUCTR2014-000162-22-RO   Belgium;Germany;Hungary;Italy;Poland;Romania;Spain;Turkey;
Metopirone 250 mg capsules/Cormeto   
   Laboratoire HRA Pharma
      2015   Phase 4   EUCTR2014-000162-22-IT   Belgium;Germany;Hungary;Italy;Poland;Spain;Sweden;Switzerland;United States;
Metyrapone   
   HRA Pharma
      2015   Phase 3   NCT02297945   Belgium;Germany;Hungary;Italy;Poland;Romania;Spain;Turkey;
   Laboratoire HRA Pharma
      2015   Phase 4   EUCTR2014-000162-22-BE   Belgium;Germany;Hungary;Italy;Poland;Spain;Sweden;Switzerland;United States;
   S.C.D.U. MEDICINA INTERNA 1 Ospedale San Luigi Orbassano
      2013   -   EUCTR2013-002063-26-IT   Italy;
Mifedren   
   Sheffield Teaching Hospitals NHS Foundation Trust
      2009   Phase 2   EUCTR2007-007604-15-GB   United Kingdom;
Mifepristone   
   Corcept Therapeutics
      2013   Phase 3   NCT01925092   United States;
      2010   Phase 3   NCT01371565   United States;
      2009   Phase 3   NCT00936741   United States;
      2007   Phase 3   NCT00569582   United States;
   HRA Pharma
      2007   Phase 2   NCT00422201   France;Germany;Italy;Netherlands;United Kingdom;United States;
   LABORATOIRE HRA PHARMA
      2007   -   EUCTR2006-004679-36-IT   France;Germany;Italy;Netherlands;
   Laboratoire HRA Pharma
      2007   -   EUCTR2006-004679-36-NL   France;Germany;Italy;Netherlands;
      2007   -   EUCTR2006-004679-36-DE   France;Germany;Italy;Netherlands;United States;
      2006   -   EUCTR2006-004679-36-FR   France;Germany;Italy;Netherlands;
   Sheffield Teaching Hospitals NHS Foundation Trust
      2008   Phase 1/Phase 2   NCT00721201   United Kingdom;
NIZORAL   
   ASSOCIAZIONE ITALIANA ENDOCRINOLOGIA-METABOLISMO-IPOFISI
      2006   -   EUCTR2006-005218-11-IT   Italy;
NON COMMERCIAL   
   Dipartimento di Medicina-DIMED, università di Padova
      2021   Phase 2   EUCTR2019-004019-29-IT   Italy;
Nevanimibe hydrochloride   
   Millendo Therapeutics, Inc.
      2017   Phase 2   EUCTR2016-002240-17-GB   United Kingdom;United States;
Nizoral   
   Erasmus MC
      2007   -   EUCTR2006-004080-55-NL   Netherlands;
OROCAL   
   Pierre Fabre Médicament
      2008   Phase 3   EUCTR2008-002280-14-FR   France;
OSTEOPOR   
   Pierre Fabre Médicament
      2008   Phase 3   EUCTR2008-002280-14-FR   France;
Octreotide   
   Erasmus MC
      2011   -   EUCTR2011-003264-77-NL   Netherlands;
Osilodrostat   
   NOVARTIS PHARMA AG
      2018   Phase 2   EUCTR2017-002840-34-IT   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
   Novartis Farmacéutica, S.A
      2018   Phase 2   EUCTR2017-002840-34-ES   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
   Novartis Farmacéutica, S.A.
      2016   Phase 3   EUCTR2014-004092-23-ES   Belgium;Brazil;Denmark;Greece;Poland;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
   Novartis Pharma AG
      2019   Phase 2   EUCTR2017-002840-34-FR   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
      2019   Phase 2   EUCTR2017-002840-34-BE   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
   Novartis Pharma Services AG
      2016   Phase 3   EUCTR2014-004092-23-PT   Belgium;Brazil;Canada;China;Costa Rica;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2016   Phase 3   EUCTR2014-004092-23-PL   Belgium;Brazil;Canada;China;Costa Rica;Denmark;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2016   Phase 3   EUCTR2014-004092-23-GR   Belgium;Brazil;Denmark;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2016   Phase 3   EUCTR2014-004092-23-BE   Belgium;Brazil;Canada;China;Costa Rica;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2015   Phase 3   EUCTR2013-004766-34-NL   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-004766-34-GB   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-004766-34-FR   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-004766-34-DE   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
      2014   Phase 3   EUCTR2013-004766-34-AT   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
   Novartis Pharmaceuticals
      2018   Phase 2   NCT03606408   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Poland;Russian Federation;Spain;Thailand;Turkey;United States;
      2016   Phase 3   NCT02697734   Belgium;Brazil;Canada;China;Costa Rica;Greece;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United States;
      2015   Phase 2   NCT02468193   Japan;
      2014   Phase 3   NCT02180217   Argentina;Australia;Austria;Bulgaria;Canada;China;Colombia;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
   Recordati AG
      2019   Phase 2   EUCTR2017-002840-34-NL   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
      2019   Phase 2   EUCTR2017-002840-34-BG   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Colombia;Costa Rica;France;Germany;Greece;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Switzerland;Thailand;Turkey;United Kingdom;United States;
      2018   Phase 2   EUCTR2017-002840-34-DE   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
      2018   Phase 2   EUCTR2017-002840-34-AT   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
      -   Phase 2   EUCTR2017-002840-34-PL   Argentina;Austria;Belgium;Brazil;Bulgaria;Canada;China;Costa Rica;France;Germany;India;Italy;Japan;Korea, Republic of;Netherlands;Poland;Portugal;Russian Federation;Spain;Thailand;Turkey;United States;
Ossein hydroxyapatite   
   Pierre Fabre Médicament
      2008   Phase 3   EUCTR2008-002280-14-FR   France;
Ovine Corticotropin-Releasing Hormone (oCRH)   
   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
      1982   -   NCT00001180   United States;
PASIREOTIDE DIASPARTATE   
   NOVARTIS FARMA S.p.A.
      2014   Phase 2   EUCTR2013-002170-49-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   Novartis Farmacéutica , S.A.
      2013   Phase 2   EUCTR2013-002170-49-ES   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   Novartis Pharma Services AG
      2015   Phase 4   EUCTR2012-002916-16-PL   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2015   Phase 4   EUCTR2012-002916-16-BE   Belgium;Brazil;Bulgaria;China;Denmark;Germany;India;Netherlands;Peru;Poland;Romania;Russian Federation;Spain;Thailand;Turkey;United States;
      2015   Phase 2   EUCTR2013-002170-49-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 4   EUCTR2012-002916-16-DK   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2014   Phase 2   EUCTR2013-002170-49-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-GR   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2013   Phase 2   EUCTR2013-002170-49-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2013   Phase 2   EUCTR2013-002170-49-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
      2011   -   EUCTR2010-024165-44-CZ   Brazil;Czech Republic;Germany;Greece;Korea, Republic of;Netherlands;Romania;Russian Federation;Spain;Thailand;United States;
PASIREOTIDE PAMOATE   
   Novartis Pharma Services AG
      2015   Phase 4   EUCTR2012-002916-16-BE   Belgium;Brazil;Bulgaria;China;Denmark;Germany;India;Netherlands;Peru;Poland;Romania;Russian Federation;Spain;Thailand;Turkey;United States;
      2014   Phase 4   EUCTR2012-002916-16-DK   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
Pasireotida 300   
   NOVARTIS FARMACEUTICA S.A.
      2011   Phase 3   EUCTR2010-024165-44-ES   Argentina;Brazil;Czech Republic;Egypt;Germany;Greece;Hungary;Korea, Republic of;Netherlands;Romania;Spain;Thailand;
Pasireotida 600   
   NOVARTIS FARMACEUTICA S.A.
      2011   Phase 3   EUCTR2010-024165-44-ES   Argentina;Brazil;Czech Republic;Egypt;Germany;Greece;Hungary;Korea, Republic of;Netherlands;Romania;Spain;Thailand;
Pasireotida 900   
   NOVARTIS FARMACEUTICA S.A.
      2011   Phase 3   EUCTR2010-024165-44-ES   Argentina;Brazil;Czech Republic;Egypt;Germany;Greece;Hungary;Korea, Republic of;Netherlands;Romania;Spain;Thailand;
Pasireotide   
   Erasmus MC
      2007   -   EUCTR2006-004080-55-NL   Netherlands;
   NOVARTIS FARMA
      2006   -   EUCTR2006-004111-22-IT   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
   Novartis Farmaceútica S.A.
      2007   -   EUCTR2006-004111-22-ES   Argentina;Belgium;Brazil;Canada;China;Denmark;Finland;France;Germany;Greece;Hungary;Israel;Italy;Mexico;Poland;Portugal;Spain;Turkey;United Kingdom;United States;
   Novartis Farmacéutica, S.A.
      2011   Phase 3   EUCTR2009-011128-70-ES   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Russian Federation;Singapore;Spain;Thailand;Turkey;United Kingdom;United States;
   Novartis Pharma Services AG
      2013   -   EUCTR2013-000267-84-FR   Australia;Belgium;Brazil;Canada;China;France;Germany;Greece;Israel;Italy;Mexico;Norway;Russian Federation;Spain;Thailand;United States;
      2012   -   EUCTR2010-024165-44-NL   Argentina;Brazil;Czech Republic;Egypt;Germany;Greece;Hungary;Korea, Republic of;Netherlands;Romania;Spain;Thailand;
      2011   Phase 3   EUCTR2010-024165-44-DE   Czech Republic;Germany;Greece;Netherlands;Spain;
      2011   -   EUCTR2010-024165-44-GR   Czech Republic;Germany;Greece;Netherlands;Spain;
      2008   Phase 3   EUCTR2006-004111-22-GB   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2008   -   EUCTR2006-004111-22-HU   Belgium;Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   Phase 3   EUCTR2006-004111-22-BE   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-PT   Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-GR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-FR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-FI   Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-DK   Belgium;Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-DE   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
   Novartis Pharmaceuticals
      2006   Phase 3   NCT00434148   Argentina;Belgium;Brazil;Canada;China;Denmark;Finland;France;Germany;Greece;Israel;Italy;Mexico;Poland;Portugal;Spain;Turkey;United States;
      2004   Phase 2   NCT00171951   France;Germany;Italy;United Kingdom;United States;
   Novartis Pharmaceuticals UK Ltd
      2005   -   EUCTR2004-002407-32-GB   Italy;United Kingdom;
   RECORDATI GROUP
      2013   Phase 4   NCT01794793   Argentina;Belgium;Brazil;Bulgaria;Canada;China;France;Germany;Greece;Hungary;India;Israel;Italy;Japan;Korea, Republic of;Malaysia;Mexico;Netherlands;Peru;Poland;Portugal;Romania;Russian Federation;Spain;Switzerland;Taiwan;Thailand;Turkey;United States;
   Recordati AG
      2017   Phase 4   EUCTR2013-000267-84-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
      2017   Phase 4   EUCTR2013-000267-84-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
Pasireotide 0.6 MG/ML   
   University of Palermo
      2013   Phase 4   NCT03080181   -
Pasireotide LAR   
   Novartis Pharma Services AG
      2015   Phase 4   EUCTR2012-002916-16-PL   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2015   Phase 4   EUCTR2012-002916-16-BE   Belgium;Brazil;Bulgaria;China;Denmark;Germany;India;Netherlands;Peru;Poland;Romania;Russian Federation;Spain;Thailand;Turkey;United States;
      2014   Phase 4   EUCTR2012-002916-16-DK   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
   Novartis Pharmaceuticals
      2014   Phase 4   NCT02060383   Belgium;Brazil;China;Denmark;Germany;India;Peru;Poland;Russian Federation;Thailand;Turkey;United States;
      2011   Phase 3   NCT01374906   Argentina;Belgium;Brazil;Canada;China;France;Germany;India;Israel;Italy;Japan;Netherlands;Peru;Poland;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
Pasireotide pamoate   
   NOVARTIS FARMA
      2013   -   EUCTR2013-000267-84-IT   Australia;Belgium;Brazil;Canada;China;Israel;Italy;Mexico;Russian Federation;Thailand;United States;
   Novartis Pharma Services AG
      2011   Phase 3   EUCTR2009-011128-70-PL   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-NL   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Netherlands;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-DE   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-BE   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
Pasireotide s.c.   
   Novartis Pharmaceuticals
      2014   Phase 4   NCT02060383   Belgium;Brazil;China;Denmark;Germany;India;Peru;Poland;Russian Federation;Thailand;Turkey;United States;
Pasireotide sub-cutaneous   
   Novartis Pharmaceuticals
      2011   Phase 3   NCT01582061   Brazil;Czech Republic;Czechia;Egypt;Germany;Greece;Korea, Republic of;Lebanon;Netherlands;Romania;Russian Federation;Spain;Thailand;United States;
Pasireotide with or without cabergoline   
   Novartis Pharmaceuticals
      2014   Phase 2   NCT01915303   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela;
Pasireotode   
   Novartis Pharma Services AG
      2007   -   EUCTR2006-004111-22-FR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
Pentetreotide   
   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
      1999   Phase 1/Phase 2   NCT00001849   United States;
Posterior RA   
   Jagiellonian University
      2006   Phase 4   NCT01959711   Poland;
R-roscovitine   
   Shlomo Melmed, MD
      2014   Phase 2   NCT02160730   United States;
RVG 08938   
   Erasmus MC
      2011   -   EUCTR2011-003264-77-NL   Netherlands;
RVG 15375   
   Erasmus MC
      2011   -   EUCTR2011-003264-77-NL   Netherlands;
RVG 18236   
   Erasmus MC
      2011   -   EUCTR2011-003264-77-NL   Netherlands;
Relacorilant   
   CORCEPT THERAPEUTICS
      2019   Phase 3   EUCTR2018-003096-35-IT   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 2   EUCTR2018-001616-30-IT   Bulgaria;Germany;Hungary;Italy;Spain;United States;
   Corcept Therapeutics
      2018   Phase 3   NCT03697109   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 2   NCT03604198   Austria;Bulgaria;Germany;Israel;Italy;Romania;Spain;United States;
   Corcept Therapeutics Incorporated
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-ES   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-DE   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2020   Phase 2;Phase 3   EUCTR2018-001616-30-BG   Austria;Bulgaria;Canada;Germany;Hungary;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-PL   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-NL   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-ES   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-DE   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-BG   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2019   Phase 3   EUCTR2018-003096-35-AT   Austria;Bulgaria;Canada;Germany;Israel;Italy;Netherlands;Poland;Romania;Spain;United States;
      2018   Phase 2   EUCTR2018-001616-30-HU   Hungary;Italy;United States;
      2016   Phase 2   EUCTR2016-000899-23-GB   Hungary;Netherlands;United Kingdom;United States;
Rosiglitazone maleate   
   Jonsson Comprehensive Cancer Center
      2007   Phase 2   NCT00612066   United States;
SOM230   
   Erasmus MC
      2007   -   EUCTR2006-004080-55-NL   Netherlands;
   NOVARTIS FARMA
      2013   -   EUCTR2013-000267-84-IT   Australia;Belgium;Brazil;Canada;China;Israel;Italy;Mexico;Russian Federation;Thailand;United States;
      2011   Phase 3   EUCTR2009-011128-70-IT   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
   NOVARTIS FARMA S.p.A.
      2014   Phase 2   EUCTR2013-002170-49-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   NOVARTIS FARMACEUTICA S.A.
      2011   Phase 3   EUCTR2010-024165-44-ES   Argentina;Brazil;Czech Republic;Egypt;Germany;Greece;Hungary;Korea, Republic of;Netherlands;Romania;Spain;Thailand;
   Novartis Farmacéutica , S.A.
      2013   Phase 2   EUCTR2013-002170-49-ES   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   Novartis Farmacéutica, S.A.
      2015   -   EUCTR2013-000267-84-ES   Argentina;Australia;Belgium;Brazil;Canada;China;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Taiwan;Thailand;United States;
      2011   Phase 3   EUCTR2009-011128-70-ES   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Russian Federation;Singapore;Spain;Thailand;Turkey;United Kingdom;United States;
   Novartis Pharma Services AG
      2016   Phase 4   EUCTR2013-000267-84-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
      2015   Phase 2   EUCTR2013-002170-49-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-GR   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2013   Phase 2   EUCTR2013-002170-49-FR   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2013   Phase 2   EUCTR2013-002170-49-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
      2013   -   EUCTR2013-000267-84-FR   Australia;Belgium;Brazil;Canada;China;France;Germany;Greece;Israel;Italy;Mexico;Norway;Russian Federation;Spain;Thailand;United States;
      2012   -   EUCTR2010-024165-44-NL   Argentina;Brazil;Czech Republic;Egypt;Germany;Greece;Hungary;Korea, Republic of;Netherlands;Romania;Spain;Thailand;
      2011   Phase 3   EUCTR2009-011128-70-PL   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-NL   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Netherlands;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-GB   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Netherlands;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-DE   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-BE   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   -   EUCTR2010-024165-44-GR   Czech Republic;Germany;Greece;Netherlands;Spain;
      2011   -   EUCTR2010-024165-44-CZ   Brazil;Czech Republic;Germany;Greece;Korea, Republic of;Netherlands;Romania;Russian Federation;Spain;Thailand;United States;
      2007   -   EUCTR2006-004111-22-DE   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
   RECORDATI GROUP
      2013   -   NCT02310269   Canada;Colombia;Denmark;France;Germany;Israel;Italy;Lebanon;Netherlands;Romania;Sweden;United Kingdom;United States;
   Recordati AG
      2017   Phase 4   EUCTR2013-000267-84-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
      2017   Phase 4   EUCTR2013-000267-84-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
      2013   Phase 4   EUCTR2013-000267-84-BE   Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Mexico;Poland;Portugal;Russian Federation;Spain;Thailand;United States;
SOM230 300µg   
   Novartis Pharma Services AG
      2011   Phase 3   EUCTR2010-024165-44-DE   Czech Republic;Germany;Greece;Netherlands;Spain;
SOM230 600µg   
   Novartis Pharma Services AG
      2011   Phase 3   EUCTR2010-024165-44-DE   Czech Republic;Germany;Greece;Netherlands;Spain;
SOM230 900µg   
   Novartis Pharma Services AG
      2011   Phase 3   EUCTR2010-024165-44-DE   Czech Republic;Germany;Greece;Netherlands;Spain;
SOM230 LAR   
   Novartis Pharma Services AG
      2015   Phase 4   EUCTR2012-002916-16-PL   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2015   Phase 4   EUCTR2012-002916-16-BE   Belgium;Brazil;Bulgaria;China;Denmark;Germany;India;Netherlands;Peru;Poland;Romania;Russian Federation;Spain;Thailand;Turkey;United States;
      2014   Phase 4   EUCTR2012-002916-16-DK   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
   Novartis Pharmaceuticals
      2011   Phase 3   NCT01374906   Argentina;Belgium;Brazil;Canada;China;France;Germany;India;Israel;Italy;Japan;Netherlands;Peru;Poland;Russian Federation;Spain;Thailand;Turkey;United Kingdom;United States;
SOM230 LAR,   
   Novartis Pharma Services AG
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
SOM230 s.c.   
   Novartis Pharmaceuticals
      2004   Phase 2   NCT00088608   France;Italy;United Kingdom;United States;
SOM230, 300micrograms   
   Novartis Pharma Services AG
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
SOM230, 600 micrograms   
   Novartis Pharma Services AG
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
SOM230, 900 micrograms   
   Novartis Pharma Services AG
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
SOM230B   
   Erasmus MC
      2007   -   EUCTR2006-004080-55-NL   Netherlands;
   NOVARTIS FARMA
      2006   -   EUCTR2006-004111-22-IT   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2004   -   EUCTR2004-002407-32-IT   Italy;United Kingdom;
   NOVARTIS FARMACEUTICA S.A.
      2011   Phase 3   EUCTR2010-024165-44-ES   Argentina;Brazil;Czech Republic;Egypt;Germany;Greece;Hungary;Korea, Republic of;Netherlands;Romania;Spain;Thailand;
   Novartis Farmaceútica S.A.
      2007   -   EUCTR2006-004111-22-ES   Argentina;Belgium;Brazil;Canada;China;Denmark;Finland;France;Germany;Greece;Hungary;Israel;Italy;Mexico;Poland;Portugal;Spain;Turkey;United Kingdom;United States;
   Novartis Pharma Services AG
      2014   Phase 4   EUCTR2012-002916-16-DK   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2008   Phase 3   EUCTR2006-004111-22-GB   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2008   -   EUCTR2006-004111-22-HU   Belgium;Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   Phase 3   EUCTR2006-004111-22-BE   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-PT   Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-GR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-FR   Belgium;Denmark;Finland;France;Germany;Greece;Hungary;Italy;Portugal;Spain;United Kingdom;
      2007   -   EUCTR2006-004111-22-FI   Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
      2007   -   EUCTR2006-004111-22-DK   Belgium;Denmark;Finland;Germany;Greece;Hungary;Italy;Portugal;United Kingdom;
   Novartis Pharmaceuticals UK Ltd
      2005   -   EUCTR2004-002407-32-GB   Italy;United Kingdom;
Seliciclib   
   Cedars-Sinai Medical Center
      2018   Phase 2   NCT03774446   United States;
Signifor   
   NOVARTIS FARMA
      2013   -   EUCTR2013-000267-84-IT   Australia;Belgium;Brazil;Canada;China;Israel;Italy;Mexico;Russian Federation;Thailand;United States;
   NOVARTIS FARMA S.p.A.
      2014   Phase 2   EUCTR2013-002170-49-IT   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
   Novartis Farmacéutica, S.A.
      2015   -   EUCTR2013-000267-84-ES   Argentina;Australia;Belgium;Brazil;Canada;China;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Russian Federation;Spain;Taiwan;Thailand;United States;
   Novartis Pharma Services AG
      2016   Phase 4   EUCTR2013-000267-84-PL   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
      2015   Phase 4   EUCTR2012-002916-16-PL   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2015   Phase 4   EUCTR2012-002916-16-BE   Belgium;Brazil;Bulgaria;China;Denmark;Germany;India;Netherlands;Peru;Poland;Romania;Russian Federation;Spain;Thailand;Turkey;United States;
      2015   Phase 2   EUCTR2013-002170-49-NL   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 4   EUCTR2012-002916-16-DK   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2014   Phase 4   EUCTR2012-002916-16-DE   Belgium;China;Denmark;Germany;Poland;Russian Federation;Turkey;United States;
      2014   Phase 2   EUCTR2013-002170-49-HU   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
      2014   Phase 2   EUCTR2013-002170-49-BE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United Kingdom;United States;Venezuela, Bolivarian Republic of;
      2013   Phase 2   EUCTR2013-002170-49-DE   Argentina;Australia;Belgium;Brazil;Bulgaria;Colombia;France;Germany;Greece;Hungary;India;Italy;Malaysia;Mexico;Netherlands;Spain;Turkey;United States;Venezuela, Bolivarian Republic of;
      2013   -   EUCTR2013-000267-84-FR   Australia;Belgium;Brazil;Canada;China;France;Germany;Greece;Israel;Italy;Mexico;Norway;Russian Federation;Spain;Thailand;United States;
      2011   Phase 3   EUCTR2010-024165-44-DE   Czech Republic;Germany;Greece;Netherlands;Spain;
      2011   Phase 3   EUCTR2009-011128-70-PL   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-NL   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Netherlands;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   Phase 3   EUCTR2009-011128-70-BE   Argentina;Belgium;Brazil;Canada;China;Germany;Italy;Japan;Peru;Poland;Spain;Thailand;Turkey;United Kingdom;United States;
      2011   -   EUCTR2010-024165-44-CZ   Brazil;Czech Republic;Germany;Greece;Korea, Republic of;Netherlands;Romania;Russian Federation;Spain;Thailand;United States;
   Recordati AG
      2017   Phase 4   EUCTR2013-000267-84-PT   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
      2017   Phase 4   EUCTR2013-000267-84-BG   Argentina;Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Korea, Republic of;Mexico;Netherlands;Poland;Portugal;Russian Federation;Spain;Taiwan;Thailand;United States;
      2013   Phase 4   EUCTR2013-000267-84-BE   Australia;Belgium;Brazil;Bulgaria;Canada;China;France;Greece;Israel;Italy;Mexico;Poland;Portugal;Russian Federation;Spain;Thailand;United States;
Silycus   
   ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.P.A.
      2021   Phase 2   EUCTR2020-005605-93-IT   Italy;
Sitagliptin   
   Novartis Pharmaceuticals
      2014   Phase 4   NCT02060383   Belgium;Brazil;China;Denmark;Germany;India;Peru;Poland;Russian Federation;Thailand;Turkey;United States;
Tadalafil   
   Andrea M. Isidori
      2016   Phase 2   NCT02611258   Italy;
   UMBERTO I - POLICLINICO DI ROMA
      2016   Phase 2   EUCTR2015-004497-15-IT   Italy;
Tretinoin   
   ISTITUTO AUXOLOGICO ITALIANO
      2008   -   EUCTR2008-006379-65-IT   Italy;
VESANOID   
   Dipartimento di Medicina-DIMED, università di Padova
      2021   Phase 2   EUCTR2019-004019-29-IT   Italy;
Valsartan   
   Hiroshima University HospitalDepartment of Endocrinology and Diabetes mellitus
      2009   -   JPRN-UMIN000002925   Japan;
Vorinostat   
   National Institute of Neurological Disorders and Stroke (NINDS)
      2022   Phase 2   NCT04339751   United States;
ZYTIGA - 250 MG - COMPRESSA - USO ORALE - FLACONE 120 COMPRESSE   
   AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA
      2016   Phase 2   EUCTR2016-000945-29-IT   Italy;