84. サルコイドーシス Disease details / Clinical trials / Drug dev / DR info


臨床試験数 : 149 / 薬物数 : 202 - (DrugBank : 78) / 標的遺伝子数 : 66 - 標的パスウェイ数 : 169

薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
13NH3 PET/CT scan   
   Mayo Clinic
      2018   Phase 4   NCT03549598   United States;
18F-FDG   
   British Columbia Cancer Agency
      2012   -   NCT01764191   Canada;
   St. Olavs Hospital
      2018   -   NCT03561025   Norway;
   Tokushima University Hospital
      2010   -   JPRN-UMIN000004267   Japan;
   University Health Network, Toronto
      2016   -   NCT03356756   Canada;
   University of Edinburgh
      2018   -   NCT03705884   United Kingdom;
18F-FSPG   
   Stanford University
      2017   Phase 2   NCT03103490   United States;
18F-fluorodeoxyglucose   
   Turku PET Centre
      2016   -   EUCTR2015-001815-11-FI   Finland;
18FDG PET/CT scan   
   Mayo Clinic
      2018   Phase 4   NCT03549598   United States;
68Ga-DOTANOC   
   Turku PET Centre
      2016   -   EUCTR2015-001815-11-FI   Finland;
68Ga-DOTATATE PET/CT   
   Mayo Clinic
      2018   Phase 4   NCT03549598   United States;
99m technetium infliximab   
   Sint Antonius Hospital
      2011   -   EUCTR2011-003630-13-NL   Netherlands;
99mTc-Infliximab   
   Sint Antonius Hospital
      2011   -   EUCTR2011-003630-13-NL   Netherlands;
ABPC   
   Respiratory medicine, Juntendo university.
      2012   -   JPRN-UMIN000008813   Japan;
ACT-293987 / JNJ-67896049   
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-IT   Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
   Actelion Pharmaceuticals Ltd
      2020   Phase 2   EUCTR2018-004887-74-DE   Belgium;Brazil;Canada;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-PL   Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-HU   Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-ES   Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-004887-74-NL   Belgium;Brazil;Canada;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-004887-74-GB   Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
ACTHAR Gel (adrenocorticotropic hormone)   
   Albany Medical College
      2015   Phase 2/Phase 3   NCT02155803   United States;
ACTHAR Gel 40 units twice weekly   
   Albany Medical College
      2015   Phase 2/Phase 3   NCT02348905   United States;
ACTHAR Gel 80 units twice weekly.   
   Albany Medical College
      2015   Phase 2/Phase 3   NCT02348905   United States;
ACZ885   
   Novartis Pharma Services AG
      2016   Phase 2   EUCTR2016-001255-49-NL   Germany;Netherlands;United States;
      2016   Phase 2   EUCTR2016-001255-49-DE   Germany;Netherlands;United States;
      2015   -   EUCTR2013-005333-21-NL   Netherlands;United States;
   Novartis Pharmaceuticals
      2016   Phase 2   NCT02888080   Germany;Netherlands;United States;
AMPC   
   Respiratory medicine, Juntendo university.
      2012   -   JPRN-UMIN000008813   Japan;
ARA 290   
   Araim Pharmaceuticals
      2013   -   EUCTR2013-003016-45-NL   Netherlands;United States;
   Araim Pharmaceuticals, Inc.
      2014   Phase 2   NCT02039687   Netherlands;United States;
ATYR1923   
   aTyr Pharma, Inc.
      2019   Phase 2   EUCTR2018-004244-33-DE   Germany;United States;
      2019   Phase 1/Phase 2   NCT03824392   United States;
Abatacept   
   University of Chicago
      2008   Phase 2   NCT00739960   United States;
Acthar Gel   
   Mallinckrodt
      2018   Phase 4   NCT03320070   United States;
Adalimumab   
   Pariser, Robert J., M.D.
      2006   Phase 2   NCT00274352   United States;
   University of Chicago
      2006   Phase 2   NCT00311246   United States;
   Wake Forest University
      2007   Phase 2   NCT00690911   United States;
All subjects will receive maraviroc 300mg orally twice a day for 6 weeks   
   Kevin F. Gibson
      2014   -   NCT02134717   United States;
Allogeneic stem cell transplantation   
   Northwestern University
      2003   Phase 1/Phase 2   NCT00282438   United States;
Ambrisentan   
   Medical University of South Carolina
      2008   Phase 2/Phase 3   NCT00851929   United States;
Anakinra   
   Virginia Commonwealth University
      2020   Phase 2   NCT04017936   United States;
Analysis of gamma globulin   
   Rennes University Hospital
      2017   -   NCT03259282   France;
Antibiotic Regimen   
   Vanderbilt University
      2010   Phase 1/Phase 2   NCT01074554   United States;
Antituberculous therapy along with steroids   
   Postgraduate Institute of Medical Education and Research
      2009   -   NCT01245036   India;
Armodafinil   
   University of Cincinnati
      2007   Phase 2/Phase 3   NCT00555347   United States;
Atorvastatin   
   National Heart, Lung, and Blood Institute (NHLBI)
      2006   Phase 2   NCT00279708   United States;
Autologous hematopoietic stem cell transplantation   
   Northwestern University
      2003   Phase 1/Phase 2   NCT00282438   United States;
Azithromycin   
   Vanderbilt University
      2014   Phase 2   NCT02024555   United States;
Azithromycin 250Mg Capsule   
   Hull University Teaching Hospitals NHS Trust
      2019   Phase 2   NCT04020380   United Kingdom;
Azithromycin monohydrate   
   Hull & East Yorkshire Hospitals NHS trust
      2019   Phase 2   EUCTR2019-000580-24-GB   United Kingdom;
Bardoxolone methyl   
   Reata Pharmaceuticals, Inc.
      2014   Phase 2   NCT02036970   Germany;Spain;United Kingdom;United States;
Blood pressure   
   Daniel Franzen
      2015   Phase 4   NCT02246023   Switzerland;
Blood sample   
   Vastra Gotaland Region
      2020   -   NCT04206163   Sweden;
Bosentan   
   Daniel Doberer
      2009   Phase 2   NCT00926627   Austria;
   Medical University of Vienna, Department of Clinical Pharmacology
      2008   -   EUCTR2007-005117-18-AT   Austria;
   University of Cincinnati
      2008   Phase 2/Phase 3   NCT00581607   United States;
Bosentan monohydrate   
   St Georges Hospital
      2007   Phase 4   EUCTR2006-005361-19-GB   United Kingdom;
Bronchoalveolar lavage (BAL)   
   Medical University of Warsaw
      2013   -   NCT01836822   Poland;
Bronchoscopy with bronchoalveolar lavage   
   Kevin F. Gibson
      2014   -   NCT02134717   United States;
C11-methionine   
   Turku PET Centre
      2016   -   EUCTR2015-001815-11-FI   Finland;
CC-100004   
   University of Cincinnati
      2008   Phase 2/Phase 3   NCT00794274   United States;
CC-220 0.3 mg Daily   
   Celgene
      2014   Phase 2   NCT02192489   -
CC-220 0.6mg Daily   
   Celgene
      2014   Phase 2   NCT02192489   -
CMK389   
   Novartis Pharma AG
      2020   Phase 2   EUCTR2018-000381-11-PL   Czechia;Denmark;Germany;Poland;United Kingdom;United States;
      2020   Phase 2   EUCTR2018-000381-11-GB   Czech Republic;Denmark;Germany;Poland;United Kingdom;United States;
      2020   Phase 2   EUCTR2018-000381-11-DK   Czechia;Denmark;Germany;Poland;United Kingdom;United States;
      2020   Phase 2   EUCTR2018-000381-11-DE   Czechia;Denmark;Germany;Poland;United Kingdom;United States;
   Novartis Pharmaceuticals
      2020   Phase 2   NCT04064242   Czechia;Denmark;Germany;Poland;United Kingdom;United States;
CNTO 148   
   Centocor BV
      2009   Phase 2   EUCTR2009-010714-30-FR   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-NL   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Janssen Biologics B.V.
      2009   Phase 2   EUCTR2009-010714-30-GB   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-DK   Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
      2009   -   EUCTR2009-010714-30-DE   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-BE   Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
CNTO1275   
   CENTOCOR
      2010   -   EUCTR2009-010714-30-IT   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Centocor BV
      2009   Phase 2   EUCTR2009-010714-30-FR   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-NL   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Janssen Biologics B.V.
      2009   Phase 2   EUCTR2009-010714-30-GB   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-DK   Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
      2009   -   EUCTR2009-010714-30-DE   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-BE   Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
CNTO148   
   CENTOCOR
      2010   -   EUCTR2009-010714-30-IT   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Calcium Citrate with Vitamin D2   
   University of Texas Southwestern Medical Center
      2010   Phase 4   NCT03621553   United States;
Canakinumab   
   Novartis Pharma Services AG
      2016   Phase 2   EUCTR2016-001255-49-NL   Germany;Netherlands;United States;
      2016   Phase 2   EUCTR2016-001255-49-DE   Germany;Netherlands;United States;
      2015   -   EUCTR2013-005333-21-NL   Netherlands;United States;
Ciclesonide   
   Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan
      2014   -   JPRN-UMIN000013831   Japan;
Clarithromycin   
   National cerebral and cardiovascular center
      2017   -   JPRN-UMIN000025936   Japan;
   Takase Hiroshi
      2017   Phase 1-2   JPRN-jRCTs031180301   Japan;
Corticosteroid   
   Oregon Health and Science University
      2019   Phase 1   NCT03793439   United States;
Cu-64 DOTATATE   
   Rigshospitalet, Denmark
      2016   -   NCT02812849   Denmark;
Cyclophosphamide   
   National Heart, Lung, and Blood Institute (NHLBI)
      1978   Phase 2   NCT00000596   -
D-methylphenidate   
   University of Cincinnati
      2006   Phase 4   NCT00361387   United States;
DELTACORTENE*10CPR   
   UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
      2008   -   EUCTR2008-001340-39-IT   Italy;
DOTANOC   
   St. Antonius Hospital
      2016   Phase 2   EUCTR2016-002160-14-NL   Netherlands;
   Turku University Hospital
      2016   Phase 2/Phase 3   NCT02824419   Finland;
Dapsone   
   National Heart, Lung, and Blood Institute (NHLBI)
      1978   Phase 2   NCT00000596   -
Dexamethasone   
   St. Antonius Hospital
      2013   Phase 3   NCT01920919   Netherlands;
Dexamethasone 0,   
Doxycycline   
   National cerebral and cardiovascular center
      2017   -   JPRN-UMIN000025936   Japan;
EBB + TBLB + BAL   
   Leiden University Medical Center
      2009   Phase 3   NCT00872612   Belgium;Denmark;Germany;Netherlands;Poland;United Kingdom;
EBUS guided transbronchial forceps biopsy (EBUS-TBFB)   
   Medical University of Warsaw
      2013   -   NCT01836822   Poland;
EBUS guided transbronchial needle aspiration (EBUS-TBNA)   
   Medical University of Warsaw
      2013   -   NCT01836822   Poland;
EUS-FNA/EBUS-TBNA + BAL   
   Leiden University Medical Center
      2009   Phase 3   NCT00872612   Belgium;Denmark;Germany;Netherlands;Poland;United Kingdom;
Endobronchial forceps biopsy   
   Medical University of Warsaw
      2013   -   NCT01836822   Poland;
Ergocalciferol   
   University of Texas Southwestern Medical Center
      2010   Phase 4   NCT03621553   United States;
Ethambutol   
   Vanderbilt University
      2014   Phase 2   NCT02024555   United States;
      2010   Phase 1   NCT01169038   United States;
FDG   
   Turku PET Centre
      2016   -   EUCTR2015-001815-11-FI   Finland;
FLUORINE (18F) FLUDEOXYGLUCOSE   
   Turku PET Centre
      2016   -   EUCTR2015-001815-11-FI   Finland;
Faecal microbiota transplantation   
   Torkell Ellingsen
      2022   Phase 2   NCT04924270   -
Fermented oyster extract   
   Pusan National University Yangsan Hospital
      2019   -   NCT04109911   Korea, Republic of;
Flexible bronchoscopy in moderate sedation   
   Daniel Franzen
      2015   Phase 4   NCT02246023   Switzerland;
Fluorodeoxyglucose   
   Yale University
      2017   Early Phase 1   NCT03048097   United States;
Folic acid   
   Murohara Toyoaki
      2016   Phase 3   JPRN-jRCTs041180111   Japan;
   Toshiyuki Nagai
      2021   Phase 3   JPRN-jRCTs011210048   Canada;Japan;United Kingdom;United States;
Ga-68-DOTA-NOC   
   St. Antonius Hospital
      2016   Phase 2   EUCTR2016-002160-14-NL   Netherlands;
Gallium-68 DOTATATE   
   Marcelo F. Di Carli, MD, FACC
      2015   -   NCT02546388   United States;
   University of Pennsylvania
      2018   -   NCT03746847   United States;
Gallium-68-DOTA-N-Octreotide   
   St. Antonius Hospital
      2016   Phase 2   EUCTR2016-002160-14-NL   Netherlands;
Glucocorticoid (prednisone or prednisolone)   
   Celgene
      2017   -   NCT03324503   Netherlands;United Kingdom;United States;
Gold   
   Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine
      2015   -   ChiCTR-DCD-15007110   China;
   Shanghai Pulmonary Hospital Tongji University, School of Medicine
      2020   Phase 0   ChiCTR2000036043   China;
Golimumab   
   CENTOCOR
      2010   -   EUCTR2009-010714-30-IT   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Centocor, Inc.
      2009   Phase 2   NCT00955279   Belgium;Denmark;France;Germany;Netherlands;Norway;Romania;Sweden;United Kingdom;United States;
Golimumab Liquid in prefilled syringe   
   Centocor BV
      2009   Phase 2   EUCTR2009-010714-30-FR   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-NL   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Janssen Biologics B.V.
      2009   Phase 2   EUCTR2009-010714-30-GB   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-DK   Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
      2009   -   EUCTR2009-010714-30-DE   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-BE   Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
H.P. Acthar Gel   
   University of Maryland, Baltimore
      2016   Phase 4   NCT02298491   United States;
Habitrol   
   Ohio State University
      2015   Phase 1/Phase 2   NCT02265874   United States;
Heparin   
   Tokushima University Hospital
      2010   -   JPRN-UMIN000004267   Japan;
Human anti TNF-alpha monoclonal antibody   
   Centocor BV
      2009   Phase 2   EUCTR2009-010714-30-FR   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-NL   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Janssen Biologics B.V.
      2009   Phase 2   EUCTR2009-010714-30-GB   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-DK   Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
      2009   -   EUCTR2009-010714-30-DE   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-BE   Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Human anti-IL 12/23 monoclonal antibody   
   Centocor BV
      2009   Phase 2   EUCTR2009-010714-30-FR   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-NL   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Janssen Biologics B.V.
      2009   Phase 2   EUCTR2009-010714-30-GB   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-DK   Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
      2009   -   EUCTR2009-010714-30-DE   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-BE   Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Humira   
   Rigshospitalet
      2006   Phase 2   EUCTR2006-001816-56-DK   Denmark;
   Wright State University
      2009   Phase 2   NCT00731757   United States;
Hydroxychloroquine   
   UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
      2008   -   EUCTR2008-001340-39-IT   Italy;
Hydroxychloroquine + Prednisone   
   University of Milano Bicocca
      2009   Phase 3   NCT02200146   Italy;
Hydroxychloroquine + low-dose prednisone   
   Assistance Publique - Hôpitaux de Paris
      2022   Phase 3   NCT05247554   -
IMod.Fc, H-Fcv3-N4   
   aTyr Pharma, Inc.
      2019   Phase 2   EUCTR2018-004244-33-DE   Germany;United States;
Iloprost   
   University of Cincinnati
      2006   Phase 4   NCT00403650   United States;
Indium-111 Pentreotide   
   Marcelo F. Di Carli, MD, FACC
      2015   -   NCT02546388   United States;
Infliximab   
   Assistance Publique - Hôpitaux de Paris
      2019   Phase 3   NCT03704610   France;
   Centocor, Inc.
      2003   Phase 3   NCT00073437   Austria;Belgium;France;Germany;Italy;Netherlands;Sweden;Switzerland;United Kingdom;United States;
Influenza Vaccine   
   Shahid Beheshti Medical University
      2008   -   NCT00828828   Iran, Islamic Republic of;
Inhaled Treprostinil   
   University of Florida
      2020   Phase 2   NCT03814317   United States;
L-METHIONINE ([11C]METHYL)   
   Turku PET Centre
      2016   -   EUCTR2015-001815-11-FI   Finland;
Large bore (19G) histologic needle biopsy of the mediastinal lymph nodes   
   Medical University of Warsaw
      2013   -   NCT01836822   Poland;
Levaquin   
   Vanderbilt University
      2010   Phase 1   NCT01169038   United States;
Levofloxacin   
   Vanderbilt University
      2014   Phase 2   NCT02024555   United States;
Low dose prednisolone   
   Postgraduate Institute of Medical Education and Research
      2017   Phase 4   NCT03265405   India;
MTX   
   Murohara Toyoaki
      2016   Phase 3   JPRN-jRCTs041180111   Japan;
Medium dose prednisolone   
   Postgraduate Institute of Medical Education and Research
      2017   Phase 4   NCT03265405   India;
Methionine   
   Turku University Hospital
      2016   Phase 2/Phase 3   NCT02824419   Finland;
Methotrexate   
   Assistance Publique - Hôpitaux de Paris
      2009   Phase 4   NCT00918554   France;
   Erasmus Medical Center
      2020   Phase 4   NCT04314193   Netherlands;
   Ottawa Heart Institute Research Corporation
      2019   Phase 3   NCT03593759   Canada;Japan;United Kingdom;United States;
   The Department of Cardiology, Nagoya University Graduate School of Medicine
      2016   -   JPRN-UMIN000022996   Japan;
   Toshiyuki Nagai
      2021   Phase 3   JPRN-jRCTs011210048   Canada;Japan;United Kingdom;United States;
Methylphenidate (overencapsulated)   
   University of East Anglia
      2016   -   NCT02643732   United Kingdom;
Methylphenidate 10mg tablets   
   Norfolk and Norwich University Hospital
      2016   Phase 2   EUCTR2016-000342-60-GB   United Kingdom;
Methylprednisolone bolus IV 15 mg/kg/d for 3 days.   
   Assistance Publique - Hôpitaux de Paris
      2012   -   NCT01652417   France;
Minomycin   
   Takase Hiroshi
      2017   Phase 1-2   JPRN-jRCTs031180301   Japan;
Mycophenolate   
   Medical University of South Carolina
      2003   Phase 3   NCT00262132   United States;
N-acetyl-cysteine   
   National Jewish Health
      2011   -   NCT01587001   United States;
Nelutri™   
   Pusan National University Yangsan Hospital
      2020   -   NCT04320121   Korea, Republic of;
Nested PCR for formalin-fixed tissues   
   Pusan National University Hospital
      2015   -   NCT02497079   Korea, Republic of;
Nested PCR for fresh tissues   
   Pusan National University Hospital
      2015   -   NCT02497079   Korea, Republic of;
Nicotine patch   
   Elliott Crouser MD
      2008   Early Phase 1   NCT00701207   United States;
None   
   Norfolk and Norwich University Hospital
      2016   Phase 2   EUCTR2016-000342-60-GB   United Kingdom;
Octreotide LAR / Sandostatin LAR (LAR=long acting release)   
   Erasmus Medical Center
      2014   -   EUCTR2013-005376-17-NL   Netherlands;
Oxygen saturation   
   Daniel Franzen
      2015   Phase 4   NCT02246023   Switzerland;
PD 0360324   
   Pfizer
      2013   Phase 2   NCT01732211   United States;
PDA001 (cenplacel-L)   
   Celularity Incorporated
      2011   Phase 1   NCT01440192   United States;
PLAQUENIL*25CPR RIV   
   UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
      2008   -   EUCTR2008-001340-39-IT   Italy;
Pentoxifylline   
   National Heart, Lung, and Blood Institute (NHLBI)
      1999   Phase 2   NCT00001877   United States;
Pirfenidone   
   University of Cincinnati
      2017   Phase 4   NCT03260556   United States;
Prednisolone   
   Erasmus Medical Center
      2020   Phase 4   NCT04314193   Netherlands;
   National cerebral and cardiovascular center
      2017   -   JPRN-UMIN000025936   Japan;
   The First Affiliated Hospital, Guangzhou Medical University
      2012   -   ChiCTR-IOR-15005953   -
   University of Edinburgh
      2018   -   NCT03705884   United Kingdom;
Prednison   
   Erasmus Medisch Centrum Dept. of Pulmonology
      2020   Phase 4   EUCTR2019-004148-31-NL   Netherlands;
Prednisone   
   National Heart, Lung, and Blood Institute (NHLBI)
      1978   Phase 2   NCT00000596   -
   Ottawa Heart Institute Research Corporation
      2014   Phase 4   NCT01210677   Canada;
   Toshiyuki Nagai
      2021   Phase 3   JPRN-jRCTs011210048   Canada;Japan;United Kingdom;United States;
   UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
      2008   -   EUCTR2008-001340-39-IT   Italy;
Prednisone or Prednisolone   
   Ottawa Heart Institute Research Corporation
      2019   Phase 3   NCT03593759   Canada;Japan;United Kingdom;United States;
Propofol dosage   
   Daniel Franzen
      2015   Phase 4   NCT02246023   Switzerland;
Quercetin   
   Maastricht University Medical Center
      2006   -   NCT00402623   Netherlands;
RNA Sequencing   
   Oregon Health and Science University
      2019   Phase 1   NCT03793439   United States;
Rapamune   
   Medical University of Vienna
      2019   Phase 2   EUCTR2017-004930-27-AT   Austria;
Real-time PCR for fresh tissues   
   Pusan National University Hospital
      2015   -   NCT02497079   Korea, Republic of;
Recovery time after bronchoscopy   
   Daniel Franzen
      2015   Phase 4   NCT02246023   Switzerland;
Remicade   
   St. Antonius Hospital
      2015   -   EUCTR2014-002224-26-NL   Netherlands;
Repository Corticotropin Injection   
   The Cleveland Clinic
      2019   Phase 4   NCT02920710   United States;
Repository Corticotropin Injection -Treatment Extension   
   The Cleveland Clinic
      2016   -   NCT02725177   United States;
Rifampin   
   Vanderbilt University
      2014   Phase 2   NCT02024555   United States;
Rifampin and azithromycin.   
   Vanderbilt University
      2010   Phase 1   NCT01169038   United States;
Riociguat   
   University of Cincinnati
      2015   Phase 4   NCT02625558   United States;
Rituximab   
   University of Cincinnati
      2009   Phase 2   NCT00855205   United States;
Roflumilast   
   University of Cincinnati
      2013   Phase 4   NCT01830959   United States;
Rubidium   
   Assistance Publique - Hôpitaux de Paris
      2012   -   NCT01648933   France;
   Yale University
      2017   Early Phase 1   NCT03048097   United States;
Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]_#1   
   Stanford University
      2019   Phase 2   NCT04008069   United States;
Schisandra chinensis extract   
   Pusan National University Yangsan Hospital
      2017   -   NCT03402308   Korea, Republic of;
Seasonal influenza vaccine available for the 2012-2013 vaccine campaign   
   Assistance Publique - Hôpitaux de Paris
      2012   Phase 3   NCT01687517   France;
Selexipag   
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-IT   Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
   Actelion
      2021   Phase 2   NCT03942211   Belgium;Brazil;Canada;Czechia;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
Sirolimus Ointment   
   Medical University of Vienna
      2019   Phase 2   EUCTR2017-004930-27-AT   Austria;
Skin biopsy   
   Kevin F. Gibson
      2014   -   NCT02134717   United States;
Tadalafil   
   University of North Carolina, Chapel Hill
      2011   Phase 2/Phase 3   NCT01324999   United States;
Tofacitinib 5 mg twice daily   
   Yale University
      2019   Phase 1   NCT03910543   United States;
Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial   
   Oregon Health and Science University
      2019   Phase 1   NCT03793439   United States;
Tofacitinib 5mg [Xeljanz] 1 year open-label extension   
   Oregon Health and Science University
      2019   Phase 1   NCT03793439   United States;
Tracleer   
   Medical University of Vienna, Department of Clinical Pharmacology
      2008   -   EUCTR2007-005117-18-AT   Austria;
   St Georges Hospital
      2007   Phase 4   EUCTR2006-005361-19-GB   United Kingdom;
Tranilast   
   The First Affiliated Hospital with Nanjing Medical University
      2018   Early Phase 1   NCT03528070   -
Uptravi   
   ACTELION PHARMACEUTICALS LTD
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-IT   Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
   Actelion Pharmaceuticals Ltd
      2020   Phase 2   EUCTR2018-004887-74-DE   Belgium;Brazil;Canada;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-PL   Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-HU   Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
      2019   Phase 2;Phase 3   EUCTR2018-004887-74-ES   Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-004887-74-NL   Belgium;Brazil;Canada;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
      2019   Phase 2   EUCTR2018-004887-74-GB   Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Ustekinumab   
   CENTOCOR
      2010   -   EUCTR2009-010714-30-IT   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Centocor, Inc.
      2009   Phase 2   NCT00955279   Belgium;Denmark;France;Germany;Netherlands;Norway;Romania;Sweden;United Kingdom;United States;
Ustekinumab liquid in prefilled syringe   
   Centocor BV
      2009   Phase 2   EUCTR2009-010714-30-FR   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-NL   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
   Janssen Biologics B.V.
      2009   Phase 2   EUCTR2009-010714-30-GB   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-DK   Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
      2009   -   EUCTR2009-010714-30-DE   Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
      2009   -   EUCTR2009-010714-30-BE   Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Venipunctures   
   Kevin F. Gibson
      2014   -   NCT02134717   United States;
Water   
   Hokkaido University Graduate School of Medicine
      2010   -   JPRN-UMIN000006533   Japan;
[64]Cu Macrin   
   Ralph Weissleder, MD
      2021   Phase 1   NCT04843891   United States;