84. サルコイドーシス Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 149 / 薬物数 : 202 - (DrugBank : 78) / 標的遺伝子数 : 66 - 標的パスウェイ数 : 169
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
13NH3 PET/CT scan
Mayo Clinic
2018 Phase 4 NCT03549598 United States;
18F-FDG
British Columbia Cancer Agency
2012 - NCT01764191 Canada;
St. Olavs Hospital
2018 - NCT03561025 Norway;
Tokushima University Hospital
2010 - JPRN-UMIN000004267 Japan;
University Health Network, Toronto
2016 - NCT03356756 Canada;
University of Edinburgh
2018 - NCT03705884 United Kingdom;
18F-FSPG
Stanford University
2017 Phase 2 NCT03103490 United States;
18F-fluorodeoxyglucose
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
18FDG PET/CT scan
Mayo Clinic
2018 Phase 4 NCT03549598 United States;
68Ga-DOTANOC
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
68Ga-DOTATATE PET/CT
Mayo Clinic
2018 Phase 4 NCT03549598 United States;
99m technetium infliximab
Sint Antonius Hospital
2011 - EUCTR2011-003630-13-NL Netherlands;
99mTc-Infliximab
Sint Antonius Hospital
2011 - EUCTR2011-003630-13-NL Netherlands;
ABPC
Respiratory medicine, Juntendo university.
2012 - JPRN-UMIN000008813 Japan;
ACT-293987 / JNJ-67896049
ACTELION PHARMACEUTICALS LTD
2019 Phase 2;Phase 3 EUCTR2018-004887-74-IT Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2020 Phase 2 EUCTR2018-004887-74-DE Belgium;Brazil;Canada;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-PL Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-HU Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-ES Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-NL Belgium;Brazil;Canada;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-GB Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
ACTHAR Gel (adrenocorticotropic hormone)
Albany Medical College
2015 Phase 2/Phase 3 NCT02155803 United States;
ACTHAR Gel 40 units twice weekly
Albany Medical College
2015 Phase 2/Phase 3 NCT02348905 United States;
ACTHAR Gel 80 units twice weekly.
Albany Medical College
2015 Phase 2/Phase 3 NCT02348905 United States;
ACZ885
Novartis Pharma Services AG
2016 Phase 2 EUCTR2016-001255-49-NL Germany;Netherlands;United States;
2016 Phase 2 EUCTR2016-001255-49-DE Germany;Netherlands;United States;
2015 - EUCTR2013-005333-21-NL Netherlands;United States;
Novartis Pharmaceuticals
2016 Phase 2 NCT02888080 Germany;Netherlands;United States;
AMPC
Respiratory medicine, Juntendo university.
2012 - JPRN-UMIN000008813 Japan;
ARA 290
Araim Pharmaceuticals
2013 - EUCTR2013-003016-45-NL Netherlands;United States;
Araim Pharmaceuticals, Inc.
2014 Phase 2 NCT02039687 Netherlands;United States;
ATYR1923
aTyr Pharma, Inc.
2019 Phase 2 EUCTR2018-004244-33-DE Germany;United States;
2019 Phase 1/Phase 2 NCT03824392 United States;
Abatacept
University of Chicago
2008 Phase 2 NCT00739960 United States;
Acthar Gel
Mallinckrodt
2018 Phase 4 NCT03320070 United States;
Adalimumab
Pariser, Robert J., M.D.
2006 Phase 2 NCT00274352 United States;
University of Chicago
2006 Phase 2 NCT00311246 United States;
Wake Forest University
2007 Phase 2 NCT00690911 United States;
All subjects will receive maraviroc 300mg orally twice a day for 6 weeks
Kevin F. Gibson
2014 - NCT02134717 United States;
Allogeneic stem cell transplantation
Northwestern University
2003 Phase 1/Phase 2 NCT00282438 United States;
Ambrisentan
Medical University of South Carolina
2008 Phase 2/Phase 3 NCT00851929 United States;
Anakinra
Virginia Commonwealth University
2020 Phase 2 NCT04017936 United States;
Analysis of gamma globulin
Rennes University Hospital
2017 - NCT03259282 France;
Antibiotic Regimen
Vanderbilt University
2010 Phase 1/Phase 2 NCT01074554 United States;
Antituberculous therapy along with steroids
Postgraduate Institute of Medical Education and Research
2009 - NCT01245036 India;
Armodafinil
University of Cincinnati
2007 Phase 2/Phase 3 NCT00555347 United States;
Atorvastatin
National Heart, Lung, and Blood Institute (NHLBI)
2006 Phase 2 NCT00279708 United States;
Autologous hematopoietic stem cell transplantation
Northwestern University
2003 Phase 1/Phase 2 NCT00282438 United States;
Azithromycin
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
Azithromycin 250Mg Capsule
Hull University Teaching Hospitals NHS Trust
2019 Phase 2 NCT04020380 United Kingdom;
Azithromycin monohydrate
Hull & East Yorkshire Hospitals NHS trust
2019 Phase 2 EUCTR2019-000580-24-GB United Kingdom;
Bardoxolone methyl
Reata Pharmaceuticals, Inc.
2014 Phase 2 NCT02036970 Germany;Spain;United Kingdom;United States;
Blood pressure
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Blood sample
Vastra Gotaland Region
2020 - NCT04206163 Sweden;
Bosentan
Daniel Doberer
2009 Phase 2 NCT00926627 Austria;
Medical University of Vienna, Department of Clinical Pharmacology
2008 - EUCTR2007-005117-18-AT Austria;
University of Cincinnati
2008 Phase 2/Phase 3 NCT00581607 United States;
Bosentan monohydrate
St Georges Hospital
2007 Phase 4 EUCTR2006-005361-19-GB United Kingdom;
Bronchoalveolar lavage (BAL)
Medical University of Warsaw
2013 - NCT01836822 Poland;
Bronchoscopy with bronchoalveolar lavage
Kevin F. Gibson
2014 - NCT02134717 United States;
C11-methionine
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
CC-100004
University of Cincinnati
2008 Phase 2/Phase 3 NCT00794274 United States;
CC-220 0.3 mg Daily
Celgene
2014 Phase 2 NCT02192489 -
CC-220 0.6mg Daily
Celgene
2014 Phase 2 NCT02192489 -
CMK389
Novartis Pharma AG
2020 Phase 2 EUCTR2018-000381-11-PL Czechia;Denmark;Germany;Poland;United Kingdom;United States;
2020 Phase 2 EUCTR2018-000381-11-GB Czech Republic;Denmark;Germany;Poland;United Kingdom;United States;
2020 Phase 2 EUCTR2018-000381-11-DK Czechia;Denmark;Germany;Poland;United Kingdom;United States;
2020 Phase 2 EUCTR2018-000381-11-DE Czechia;Denmark;Germany;Poland;United Kingdom;United States;
Novartis Pharmaceuticals
2020 Phase 2 NCT04064242 Czechia;Denmark;Germany;Poland;United Kingdom;United States;
CNTO 148
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
CNTO1275
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
CNTO148
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Calcium Citrate with Vitamin D2
University of Texas Southwestern Medical Center
2010 Phase 4 NCT03621553 United States;
Canakinumab
Novartis Pharma Services AG
2016 Phase 2 EUCTR2016-001255-49-NL Germany;Netherlands;United States;
2016 Phase 2 EUCTR2016-001255-49-DE Germany;Netherlands;United States;
2015 - EUCTR2013-005333-21-NL Netherlands;United States;
Ciclesonide
Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan
2014 - JPRN-UMIN000013831 Japan;
Clarithromycin
National cerebral and cardiovascular center
2017 - JPRN-UMIN000025936 Japan;
Takase Hiroshi
2017 Phase 1-2 JPRN-jRCTs031180301 Japan;
Corticosteroid
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Cu-64 DOTATATE
Rigshospitalet, Denmark
2016 - NCT02812849 Denmark;
Cyclophosphamide
National Heart, Lung, and Blood Institute (NHLBI)
1978 Phase 2 NCT00000596 -
D-methylphenidate
University of Cincinnati
2006 Phase 4 NCT00361387 United States;
DELTACORTENE*10CPR
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
DOTANOC
St. Antonius Hospital
2016 Phase 2 EUCTR2016-002160-14-NL Netherlands;
Turku University Hospital
2016 Phase 2/Phase 3 NCT02824419 Finland;
Dapsone
National Heart, Lung, and Blood Institute (NHLBI)
1978 Phase 2 NCT00000596 -
Dexamethasone
St. Antonius Hospital
2013 Phase 3 NCT01920919 Netherlands;
Dexamethasone 0,
Doxycycline
National cerebral and cardiovascular center
2017 - JPRN-UMIN000025936 Japan;
EBB + TBLB + BAL
Leiden University Medical Center
2009 Phase 3 NCT00872612 Belgium;Denmark;Germany;Netherlands;Poland;United Kingdom;
EBUS guided transbronchial forceps biopsy (EBUS-TBFB)
Medical University of Warsaw
2013 - NCT01836822 Poland;
EBUS guided transbronchial needle aspiration (EBUS-TBNA)
Medical University of Warsaw
2013 - NCT01836822 Poland;
EUS-FNA/EBUS-TBNA + BAL
Leiden University Medical Center
2009 Phase 3 NCT00872612 Belgium;Denmark;Germany;Netherlands;Poland;United Kingdom;
Endobronchial forceps biopsy
Medical University of Warsaw
2013 - NCT01836822 Poland;
Ergocalciferol
University of Texas Southwestern Medical Center
2010 Phase 4 NCT03621553 United States;
Ethambutol
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
2010 Phase 1 NCT01169038 United States;
FDG
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
FLUORINE (18F) FLUDEOXYGLUCOSE
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
Faecal microbiota transplantation
Torkell Ellingsen
2022 Phase 2 NCT04924270 -
Fermented oyster extract
Pusan National University Yangsan Hospital
2019 - NCT04109911 Korea, Republic of;
Flexible bronchoscopy in moderate sedation
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Fluorodeoxyglucose
Yale University
2017 Early Phase 1 NCT03048097 United States;
Folic acid
Murohara Toyoaki
2016 Phase 3 JPRN-jRCTs041180111 Japan;
Toshiyuki Nagai
2021 Phase 3 JPRN-jRCTs011210048 Canada;Japan;United Kingdom;United States;
Ga-68-DOTA-NOC
St. Antonius Hospital
2016 Phase 2 EUCTR2016-002160-14-NL Netherlands;
Gallium-68 DOTATATE
Marcelo F. Di Carli, MD, FACC
2015 - NCT02546388 United States;
University of Pennsylvania
2018 - NCT03746847 United States;
Gallium-68-DOTA-N-Octreotide
St. Antonius Hospital
2016 Phase 2 EUCTR2016-002160-14-NL Netherlands;
Glucocorticoid (prednisone or prednisolone)
Celgene
2017 - NCT03324503 Netherlands;United Kingdom;United States;
Gold
Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine
2015 - ChiCTR-DCD-15007110 China;
Shanghai Pulmonary Hospital Tongji University, School of Medicine
2020 Phase 0 ChiCTR2000036043 China;
Golimumab
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Centocor, Inc.
2009 Phase 2 NCT00955279 Belgium;Denmark;France;Germany;Netherlands;Norway;Romania;Sweden;United Kingdom;United States;
Golimumab Liquid in prefilled syringe
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
H.P. Acthar Gel
University of Maryland, Baltimore
2016 Phase 4 NCT02298491 United States;
Habitrol
Ohio State University
2015 Phase 1/Phase 2 NCT02265874 United States;
Heparin
Tokushima University Hospital
2010 - JPRN-UMIN000004267 Japan;
Human anti TNF-alpha monoclonal antibody
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Human anti-IL 12/23 monoclonal antibody
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Humira
Rigshospitalet
2006 Phase 2 EUCTR2006-001816-56-DK Denmark;
Wright State University
2009 Phase 2 NCT00731757 United States;
Hydroxychloroquine
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
Hydroxychloroquine + Prednisone
University of Milano Bicocca
2009 Phase 3 NCT02200146 Italy;
Hydroxychloroquine + low-dose prednisone
Assistance Publique - Hôpitaux de Paris
2022 Phase 3 NCT05247554 -
IMod.Fc, H-Fcv3-N4
aTyr Pharma, Inc.
2019 Phase 2 EUCTR2018-004244-33-DE Germany;United States;
Iloprost
University of Cincinnati
2006 Phase 4 NCT00403650 United States;
Indium-111 Pentreotide
Marcelo F. Di Carli, MD, FACC
2015 - NCT02546388 United States;
Infliximab
Assistance Publique - Hôpitaux de Paris
2019 Phase 3 NCT03704610 France;
Centocor, Inc.
2003 Phase 3 NCT00073437 Austria;Belgium;France;Germany;Italy;Netherlands;Sweden;Switzerland;United Kingdom;United States;
Influenza Vaccine
Shahid Beheshti Medical University
2008 - NCT00828828 Iran, Islamic Republic of;
Inhaled Treprostinil
University of Florida
2020 Phase 2 NCT03814317 United States;
L-METHIONINE ([11C]METHYL)
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
Large bore (19G) histologic needle biopsy of the mediastinal lymph nodes
Medical University of Warsaw
2013 - NCT01836822 Poland;
Levaquin
Vanderbilt University
2010 Phase 1 NCT01169038 United States;
Levofloxacin
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
Low dose prednisolone
Postgraduate Institute of Medical Education and Research
2017 Phase 4 NCT03265405 India;
MTX
Murohara Toyoaki
2016 Phase 3 JPRN-jRCTs041180111 Japan;
Medium dose prednisolone
Postgraduate Institute of Medical Education and Research
2017 Phase 4 NCT03265405 India;
Methionine
Turku University Hospital
2016 Phase 2/Phase 3 NCT02824419 Finland;
Methotrexate
Assistance Publique - Hôpitaux de Paris
2009 Phase 4 NCT00918554 France;
Erasmus Medical Center
2020 Phase 4 NCT04314193 Netherlands;
Ottawa Heart Institute Research Corporation
2019 Phase 3 NCT03593759 Canada;Japan;United Kingdom;United States;
The Department of Cardiology, Nagoya University Graduate School of Medicine
2016 - JPRN-UMIN000022996 Japan;
Toshiyuki Nagai
2021 Phase 3 JPRN-jRCTs011210048 Canada;Japan;United Kingdom;United States;
Methylphenidate (overencapsulated)
University of East Anglia
2016 - NCT02643732 United Kingdom;
Methylphenidate 10mg tablets
Norfolk and Norwich University Hospital
2016 Phase 2 EUCTR2016-000342-60-GB United Kingdom;
Methylprednisolone bolus IV 15 mg/kg/d for 3 days.
Assistance Publique - Hôpitaux de Paris
2012 - NCT01652417 France;
Minomycin
Takase Hiroshi
2017 Phase 1-2 JPRN-jRCTs031180301 Japan;
Mycophenolate
Medical University of South Carolina
2003 Phase 3 NCT00262132 United States;
N-acetyl-cysteine
National Jewish Health
2011 - NCT01587001 United States;
Nelutri™
Pusan National University Yangsan Hospital
2020 - NCT04320121 Korea, Republic of;
Nested PCR for formalin-fixed tissues
Pusan National University Hospital
2015 - NCT02497079 Korea, Republic of;
Nested PCR for fresh tissues
Pusan National University Hospital
2015 - NCT02497079 Korea, Republic of;
Nicotine patch
Elliott Crouser MD
2008 Early Phase 1 NCT00701207 United States;
None
Norfolk and Norwich University Hospital
2016 Phase 2 EUCTR2016-000342-60-GB United Kingdom;
Octreotide LAR / Sandostatin LAR (LAR=long acting release)
Erasmus Medical Center
2014 - EUCTR2013-005376-17-NL Netherlands;
Oxygen saturation
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
PD 0360324
Pfizer
2013 Phase 2 NCT01732211 United States;
PDA001 (cenplacel-L)
Celularity Incorporated
2011 Phase 1 NCT01440192 United States;
PLAQUENIL*25CPR RIV
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
Pentoxifylline
National Heart, Lung, and Blood Institute (NHLBI)
1999 Phase 2 NCT00001877 United States;
Pirfenidone
University of Cincinnati
2017 Phase 4 NCT03260556 United States;
Prednisolone
Erasmus Medical Center
2020 Phase 4 NCT04314193 Netherlands;
National cerebral and cardiovascular center
2017 - JPRN-UMIN000025936 Japan;
The First Affiliated Hospital, Guangzhou Medical University
2012 - ChiCTR-IOR-15005953 -
University of Edinburgh
2018 - NCT03705884 United Kingdom;
Prednison
Erasmus Medisch Centrum Dept. of Pulmonology
2020 Phase 4 EUCTR2019-004148-31-NL Netherlands;
Prednisone
National Heart, Lung, and Blood Institute (NHLBI)
1978 Phase 2 NCT00000596 -
Ottawa Heart Institute Research Corporation
2014 Phase 4 NCT01210677 Canada;
Toshiyuki Nagai
2021 Phase 3 JPRN-jRCTs011210048 Canada;Japan;United Kingdom;United States;
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
Prednisone or Prednisolone
Ottawa Heart Institute Research Corporation
2019 Phase 3 NCT03593759 Canada;Japan;United Kingdom;United States;
Propofol dosage
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Quercetin
Maastricht University Medical Center
2006 - NCT00402623 Netherlands;
RNA Sequencing
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Rapamune
Medical University of Vienna
2019 Phase 2 EUCTR2017-004930-27-AT Austria;
Real-time PCR for fresh tissues
Pusan National University Hospital
2015 - NCT02497079 Korea, Republic of;
Recovery time after bronchoscopy
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Remicade
St. Antonius Hospital
2015 - EUCTR2014-002224-26-NL Netherlands;
Repository Corticotropin Injection
The Cleveland Clinic
2019 Phase 4 NCT02920710 United States;
Repository Corticotropin Injection -Treatment Extension
The Cleveland Clinic
2016 - NCT02725177 United States;
Rifampin
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
Rifampin and azithromycin.
Vanderbilt University
2010 Phase 1 NCT01169038 United States;
Riociguat
University of Cincinnati
2015 Phase 4 NCT02625558 United States;
Rituximab
University of Cincinnati
2009 Phase 2 NCT00855205 United States;
Roflumilast
University of Cincinnati
2013 Phase 4 NCT01830959 United States;
Rubidium
Assistance Publique - Hôpitaux de Paris
2012 - NCT01648933 France;
Yale University
2017 Early Phase 1 NCT03048097 United States;
Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]_#1
Stanford University
2019 Phase 2 NCT04008069 United States;
Schisandra chinensis extract
Pusan National University Yangsan Hospital
2017 - NCT03402308 Korea, Republic of;
Seasonal influenza vaccine available for the 2012-2013 vaccine campaign
Assistance Publique - Hôpitaux de Paris
2012 Phase 3 NCT01687517 France;
Selexipag
ACTELION PHARMACEUTICALS LTD
2019 Phase 2;Phase 3 EUCTR2018-004887-74-IT Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Actelion
2021 Phase 2 NCT03942211 Belgium;Brazil;Canada;Czechia;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
Sirolimus Ointment
Medical University of Vienna
2019 Phase 2 EUCTR2017-004930-27-AT Austria;
Skin biopsy
Kevin F. Gibson
2014 - NCT02134717 United States;
Tadalafil
University of North Carolina, Chapel Hill
2011 Phase 2/Phase 3 NCT01324999 United States;
Tofacitinib 5 mg twice daily
Yale University
2019 Phase 1 NCT03910543 United States;
Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Tofacitinib 5mg [Xeljanz] 1 year open-label extension
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Tracleer
Medical University of Vienna, Department of Clinical Pharmacology
2008 - EUCTR2007-005117-18-AT Austria;
St Georges Hospital
2007 Phase 4 EUCTR2006-005361-19-GB United Kingdom;
Tranilast
The First Affiliated Hospital with Nanjing Medical University
2018 Early Phase 1 NCT03528070 -
Uptravi
ACTELION PHARMACEUTICALS LTD
2019 Phase 2;Phase 3 EUCTR2018-004887-74-IT Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2020 Phase 2 EUCTR2018-004887-74-DE Belgium;Brazil;Canada;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-PL Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-HU Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-ES Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-NL Belgium;Brazil;Canada;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-GB Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Ustekinumab
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Centocor, Inc.
2009 Phase 2 NCT00955279 Belgium;Denmark;France;Germany;Netherlands;Norway;Romania;Sweden;United Kingdom;United States;
Ustekinumab liquid in prefilled syringe
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Venipunctures
Kevin F. Gibson
2014 - NCT02134717 United States;
Water
Hokkaido University Graduate School of Medicine
2010 - JPRN-UMIN000006533 Japan;
[64]Cu Macrin
Ralph Weissleder, MD
2021 Phase 1 NCT04843891 United States;
Mayo Clinic
2018 Phase 4 NCT03549598 United States;
18F-FDG
British Columbia Cancer Agency
2012 - NCT01764191 Canada;
St. Olavs Hospital
2018 - NCT03561025 Norway;
Tokushima University Hospital
2010 - JPRN-UMIN000004267 Japan;
University Health Network, Toronto
2016 - NCT03356756 Canada;
University of Edinburgh
2018 - NCT03705884 United Kingdom;
18F-FSPG
Stanford University
2017 Phase 2 NCT03103490 United States;
18F-fluorodeoxyglucose
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
18FDG PET/CT scan
Mayo Clinic
2018 Phase 4 NCT03549598 United States;
68Ga-DOTANOC
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
68Ga-DOTATATE PET/CT
Mayo Clinic
2018 Phase 4 NCT03549598 United States;
99m technetium infliximab
Sint Antonius Hospital
2011 - EUCTR2011-003630-13-NL Netherlands;
99mTc-Infliximab
Sint Antonius Hospital
2011 - EUCTR2011-003630-13-NL Netherlands;
ABPC
Respiratory medicine, Juntendo university.
2012 - JPRN-UMIN000008813 Japan;
ACT-293987 / JNJ-67896049
ACTELION PHARMACEUTICALS LTD
2019 Phase 2;Phase 3 EUCTR2018-004887-74-IT Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2020 Phase 2 EUCTR2018-004887-74-DE Belgium;Brazil;Canada;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-PL Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-HU Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-ES Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-NL Belgium;Brazil;Canada;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-GB Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
ACTHAR Gel (adrenocorticotropic hormone)
Albany Medical College
2015 Phase 2/Phase 3 NCT02155803 United States;
ACTHAR Gel 40 units twice weekly
Albany Medical College
2015 Phase 2/Phase 3 NCT02348905 United States;
ACTHAR Gel 80 units twice weekly.
Albany Medical College
2015 Phase 2/Phase 3 NCT02348905 United States;
ACZ885
Novartis Pharma Services AG
2016 Phase 2 EUCTR2016-001255-49-NL Germany;Netherlands;United States;
2016 Phase 2 EUCTR2016-001255-49-DE Germany;Netherlands;United States;
2015 - EUCTR2013-005333-21-NL Netherlands;United States;
Novartis Pharmaceuticals
2016 Phase 2 NCT02888080 Germany;Netherlands;United States;
AMPC
Respiratory medicine, Juntendo university.
2012 - JPRN-UMIN000008813 Japan;
ARA 290
Araim Pharmaceuticals
2013 - EUCTR2013-003016-45-NL Netherlands;United States;
Araim Pharmaceuticals, Inc.
2014 Phase 2 NCT02039687 Netherlands;United States;
ATYR1923
aTyr Pharma, Inc.
2019 Phase 2 EUCTR2018-004244-33-DE Germany;United States;
2019 Phase 1/Phase 2 NCT03824392 United States;
Abatacept
University of Chicago
2008 Phase 2 NCT00739960 United States;
Acthar Gel
Mallinckrodt
2018 Phase 4 NCT03320070 United States;
Adalimumab
Pariser, Robert J., M.D.
2006 Phase 2 NCT00274352 United States;
University of Chicago
2006 Phase 2 NCT00311246 United States;
Wake Forest University
2007 Phase 2 NCT00690911 United States;
All subjects will receive maraviroc 300mg orally twice a day for 6 weeks
Kevin F. Gibson
2014 - NCT02134717 United States;
Allogeneic stem cell transplantation
Northwestern University
2003 Phase 1/Phase 2 NCT00282438 United States;
Ambrisentan
Medical University of South Carolina
2008 Phase 2/Phase 3 NCT00851929 United States;
Anakinra
Virginia Commonwealth University
2020 Phase 2 NCT04017936 United States;
Analysis of gamma globulin
Rennes University Hospital
2017 - NCT03259282 France;
Antibiotic Regimen
Vanderbilt University
2010 Phase 1/Phase 2 NCT01074554 United States;
Antituberculous therapy along with steroids
Postgraduate Institute of Medical Education and Research
2009 - NCT01245036 India;
Armodafinil
University of Cincinnati
2007 Phase 2/Phase 3 NCT00555347 United States;
Atorvastatin
National Heart, Lung, and Blood Institute (NHLBI)
2006 Phase 2 NCT00279708 United States;
Autologous hematopoietic stem cell transplantation
Northwestern University
2003 Phase 1/Phase 2 NCT00282438 United States;
Azithromycin
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
Azithromycin 250Mg Capsule
Hull University Teaching Hospitals NHS Trust
2019 Phase 2 NCT04020380 United Kingdom;
Azithromycin monohydrate
Hull & East Yorkshire Hospitals NHS trust
2019 Phase 2 EUCTR2019-000580-24-GB United Kingdom;
Bardoxolone methyl
Reata Pharmaceuticals, Inc.
2014 Phase 2 NCT02036970 Germany;Spain;United Kingdom;United States;
Blood pressure
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Blood sample
Vastra Gotaland Region
2020 - NCT04206163 Sweden;
Bosentan
Daniel Doberer
2009 Phase 2 NCT00926627 Austria;
Medical University of Vienna, Department of Clinical Pharmacology
2008 - EUCTR2007-005117-18-AT Austria;
University of Cincinnati
2008 Phase 2/Phase 3 NCT00581607 United States;
Bosentan monohydrate
St Georges Hospital
2007 Phase 4 EUCTR2006-005361-19-GB United Kingdom;
Bronchoalveolar lavage (BAL)
Medical University of Warsaw
2013 - NCT01836822 Poland;
Bronchoscopy with bronchoalveolar lavage
Kevin F. Gibson
2014 - NCT02134717 United States;
C11-methionine
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
CC-100004
University of Cincinnati
2008 Phase 2/Phase 3 NCT00794274 United States;
CC-220 0.3 mg Daily
Celgene
2014 Phase 2 NCT02192489 -
CC-220 0.6mg Daily
Celgene
2014 Phase 2 NCT02192489 -
CMK389
Novartis Pharma AG
2020 Phase 2 EUCTR2018-000381-11-PL Czechia;Denmark;Germany;Poland;United Kingdom;United States;
2020 Phase 2 EUCTR2018-000381-11-GB Czech Republic;Denmark;Germany;Poland;United Kingdom;United States;
2020 Phase 2 EUCTR2018-000381-11-DK Czechia;Denmark;Germany;Poland;United Kingdom;United States;
2020 Phase 2 EUCTR2018-000381-11-DE Czechia;Denmark;Germany;Poland;United Kingdom;United States;
Novartis Pharmaceuticals
2020 Phase 2 NCT04064242 Czechia;Denmark;Germany;Poland;United Kingdom;United States;
CNTO 148
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
CNTO1275
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
CNTO148
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Calcium Citrate with Vitamin D2
University of Texas Southwestern Medical Center
2010 Phase 4 NCT03621553 United States;
Canakinumab
Novartis Pharma Services AG
2016 Phase 2 EUCTR2016-001255-49-NL Germany;Netherlands;United States;
2016 Phase 2 EUCTR2016-001255-49-DE Germany;Netherlands;United States;
2015 - EUCTR2013-005333-21-NL Netherlands;United States;
Ciclesonide
Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan
2014 - JPRN-UMIN000013831 Japan;
Clarithromycin
National cerebral and cardiovascular center
2017 - JPRN-UMIN000025936 Japan;
Takase Hiroshi
2017 Phase 1-2 JPRN-jRCTs031180301 Japan;
Corticosteroid
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Cu-64 DOTATATE
Rigshospitalet, Denmark
2016 - NCT02812849 Denmark;
Cyclophosphamide
National Heart, Lung, and Blood Institute (NHLBI)
1978 Phase 2 NCT00000596 -
D-methylphenidate
University of Cincinnati
2006 Phase 4 NCT00361387 United States;
DELTACORTENE*10CPR
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
DOTANOC
St. Antonius Hospital
2016 Phase 2 EUCTR2016-002160-14-NL Netherlands;
Turku University Hospital
2016 Phase 2/Phase 3 NCT02824419 Finland;
Dapsone
National Heart, Lung, and Blood Institute (NHLBI)
1978 Phase 2 NCT00000596 -
Dexamethasone
St. Antonius Hospital
2013 Phase 3 NCT01920919 Netherlands;
Dexamethasone 0,
Doxycycline
National cerebral and cardiovascular center
2017 - JPRN-UMIN000025936 Japan;
EBB + TBLB + BAL
Leiden University Medical Center
2009 Phase 3 NCT00872612 Belgium;Denmark;Germany;Netherlands;Poland;United Kingdom;
EBUS guided transbronchial forceps biopsy (EBUS-TBFB)
Medical University of Warsaw
2013 - NCT01836822 Poland;
EBUS guided transbronchial needle aspiration (EBUS-TBNA)
Medical University of Warsaw
2013 - NCT01836822 Poland;
EUS-FNA/EBUS-TBNA + BAL
Leiden University Medical Center
2009 Phase 3 NCT00872612 Belgium;Denmark;Germany;Netherlands;Poland;United Kingdom;
Endobronchial forceps biopsy
Medical University of Warsaw
2013 - NCT01836822 Poland;
Ergocalciferol
University of Texas Southwestern Medical Center
2010 Phase 4 NCT03621553 United States;
Ethambutol
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
2010 Phase 1 NCT01169038 United States;
FDG
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
FLUORINE (18F) FLUDEOXYGLUCOSE
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
Faecal microbiota transplantation
Torkell Ellingsen
2022 Phase 2 NCT04924270 -
Fermented oyster extract
Pusan National University Yangsan Hospital
2019 - NCT04109911 Korea, Republic of;
Flexible bronchoscopy in moderate sedation
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Fluorodeoxyglucose
Yale University
2017 Early Phase 1 NCT03048097 United States;
Folic acid
Murohara Toyoaki
2016 Phase 3 JPRN-jRCTs041180111 Japan;
Toshiyuki Nagai
2021 Phase 3 JPRN-jRCTs011210048 Canada;Japan;United Kingdom;United States;
Ga-68-DOTA-NOC
St. Antonius Hospital
2016 Phase 2 EUCTR2016-002160-14-NL Netherlands;
Gallium-68 DOTATATE
Marcelo F. Di Carli, MD, FACC
2015 - NCT02546388 United States;
University of Pennsylvania
2018 - NCT03746847 United States;
Gallium-68-DOTA-N-Octreotide
St. Antonius Hospital
2016 Phase 2 EUCTR2016-002160-14-NL Netherlands;
Glucocorticoid (prednisone or prednisolone)
Celgene
2017 - NCT03324503 Netherlands;United Kingdom;United States;
Gold
Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine
2015 - ChiCTR-DCD-15007110 China;
Shanghai Pulmonary Hospital Tongji University, School of Medicine
2020 Phase 0 ChiCTR2000036043 China;
Golimumab
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Centocor, Inc.
2009 Phase 2 NCT00955279 Belgium;Denmark;France;Germany;Netherlands;Norway;Romania;Sweden;United Kingdom;United States;
Golimumab Liquid in prefilled syringe
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
H.P. Acthar Gel
University of Maryland, Baltimore
2016 Phase 4 NCT02298491 United States;
Habitrol
Ohio State University
2015 Phase 1/Phase 2 NCT02265874 United States;
Heparin
Tokushima University Hospital
2010 - JPRN-UMIN000004267 Japan;
Human anti TNF-alpha monoclonal antibody
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Human anti-IL 12/23 monoclonal antibody
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Humira
Rigshospitalet
2006 Phase 2 EUCTR2006-001816-56-DK Denmark;
Wright State University
2009 Phase 2 NCT00731757 United States;
Hydroxychloroquine
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
Hydroxychloroquine + Prednisone
University of Milano Bicocca
2009 Phase 3 NCT02200146 Italy;
Hydroxychloroquine + low-dose prednisone
Assistance Publique - Hôpitaux de Paris
2022 Phase 3 NCT05247554 -
IMod.Fc, H-Fcv3-N4
aTyr Pharma, Inc.
2019 Phase 2 EUCTR2018-004244-33-DE Germany;United States;
Iloprost
University of Cincinnati
2006 Phase 4 NCT00403650 United States;
Indium-111 Pentreotide
Marcelo F. Di Carli, MD, FACC
2015 - NCT02546388 United States;
Infliximab
Assistance Publique - Hôpitaux de Paris
2019 Phase 3 NCT03704610 France;
Centocor, Inc.
2003 Phase 3 NCT00073437 Austria;Belgium;France;Germany;Italy;Netherlands;Sweden;Switzerland;United Kingdom;United States;
Influenza Vaccine
Shahid Beheshti Medical University
2008 - NCT00828828 Iran, Islamic Republic of;
Inhaled Treprostinil
University of Florida
2020 Phase 2 NCT03814317 United States;
L-METHIONINE ([11C]METHYL)
Turku PET Centre
2016 - EUCTR2015-001815-11-FI Finland;
Large bore (19G) histologic needle biopsy of the mediastinal lymph nodes
Medical University of Warsaw
2013 - NCT01836822 Poland;
Levaquin
Vanderbilt University
2010 Phase 1 NCT01169038 United States;
Levofloxacin
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
Low dose prednisolone
Postgraduate Institute of Medical Education and Research
2017 Phase 4 NCT03265405 India;
MTX
Murohara Toyoaki
2016 Phase 3 JPRN-jRCTs041180111 Japan;
Medium dose prednisolone
Postgraduate Institute of Medical Education and Research
2017 Phase 4 NCT03265405 India;
Methionine
Turku University Hospital
2016 Phase 2/Phase 3 NCT02824419 Finland;
Methotrexate
Assistance Publique - Hôpitaux de Paris
2009 Phase 4 NCT00918554 France;
Erasmus Medical Center
2020 Phase 4 NCT04314193 Netherlands;
Ottawa Heart Institute Research Corporation
2019 Phase 3 NCT03593759 Canada;Japan;United Kingdom;United States;
The Department of Cardiology, Nagoya University Graduate School of Medicine
2016 - JPRN-UMIN000022996 Japan;
Toshiyuki Nagai
2021 Phase 3 JPRN-jRCTs011210048 Canada;Japan;United Kingdom;United States;
Methylphenidate (overencapsulated)
University of East Anglia
2016 - NCT02643732 United Kingdom;
Methylphenidate 10mg tablets
Norfolk and Norwich University Hospital
2016 Phase 2 EUCTR2016-000342-60-GB United Kingdom;
Methylprednisolone bolus IV 15 mg/kg/d for 3 days.
Assistance Publique - Hôpitaux de Paris
2012 - NCT01652417 France;
Minomycin
Takase Hiroshi
2017 Phase 1-2 JPRN-jRCTs031180301 Japan;
Mycophenolate
Medical University of South Carolina
2003 Phase 3 NCT00262132 United States;
N-acetyl-cysteine
National Jewish Health
2011 - NCT01587001 United States;
Nelutri™
Pusan National University Yangsan Hospital
2020 - NCT04320121 Korea, Republic of;
Nested PCR for formalin-fixed tissues
Pusan National University Hospital
2015 - NCT02497079 Korea, Republic of;
Nested PCR for fresh tissues
Pusan National University Hospital
2015 - NCT02497079 Korea, Republic of;
Nicotine patch
Elliott Crouser MD
2008 Early Phase 1 NCT00701207 United States;
None
Norfolk and Norwich University Hospital
2016 Phase 2 EUCTR2016-000342-60-GB United Kingdom;
Octreotide LAR / Sandostatin LAR (LAR=long acting release)
Erasmus Medical Center
2014 - EUCTR2013-005376-17-NL Netherlands;
Oxygen saturation
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
PD 0360324
Pfizer
2013 Phase 2 NCT01732211 United States;
PDA001 (cenplacel-L)
Celularity Incorporated
2011 Phase 1 NCT01440192 United States;
PLAQUENIL*25CPR RIV
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
Pentoxifylline
National Heart, Lung, and Blood Institute (NHLBI)
1999 Phase 2 NCT00001877 United States;
Pirfenidone
University of Cincinnati
2017 Phase 4 NCT03260556 United States;
Prednisolone
Erasmus Medical Center
2020 Phase 4 NCT04314193 Netherlands;
National cerebral and cardiovascular center
2017 - JPRN-UMIN000025936 Japan;
The First Affiliated Hospital, Guangzhou Medical University
2012 - ChiCTR-IOR-15005953 -
University of Edinburgh
2018 - NCT03705884 United Kingdom;
Prednison
Erasmus Medisch Centrum Dept. of Pulmonology
2020 Phase 4 EUCTR2019-004148-31-NL Netherlands;
Prednisone
National Heart, Lung, and Blood Institute (NHLBI)
1978 Phase 2 NCT00000596 -
Ottawa Heart Institute Research Corporation
2014 Phase 4 NCT01210677 Canada;
Toshiyuki Nagai
2021 Phase 3 JPRN-jRCTs011210048 Canada;Japan;United Kingdom;United States;
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
2008 - EUCTR2008-001340-39-IT Italy;
Prednisone or Prednisolone
Ottawa Heart Institute Research Corporation
2019 Phase 3 NCT03593759 Canada;Japan;United Kingdom;United States;
Propofol dosage
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Quercetin
Maastricht University Medical Center
2006 - NCT00402623 Netherlands;
RNA Sequencing
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Rapamune
Medical University of Vienna
2019 Phase 2 EUCTR2017-004930-27-AT Austria;
Real-time PCR for fresh tissues
Pusan National University Hospital
2015 - NCT02497079 Korea, Republic of;
Recovery time after bronchoscopy
Daniel Franzen
2015 Phase 4 NCT02246023 Switzerland;
Remicade
St. Antonius Hospital
2015 - EUCTR2014-002224-26-NL Netherlands;
Repository Corticotropin Injection
The Cleveland Clinic
2019 Phase 4 NCT02920710 United States;
Repository Corticotropin Injection -Treatment Extension
The Cleveland Clinic
2016 - NCT02725177 United States;
Rifampin
Vanderbilt University
2014 Phase 2 NCT02024555 United States;
Rifampin and azithromycin.
Vanderbilt University
2010 Phase 1 NCT01169038 United States;
Riociguat
University of Cincinnati
2015 Phase 4 NCT02625558 United States;
Rituximab
University of Cincinnati
2009 Phase 2 NCT00855205 United States;
Roflumilast
University of Cincinnati
2013 Phase 4 NCT01830959 United States;
Rubidium
Assistance Publique - Hôpitaux de Paris
2012 - NCT01648933 France;
Yale University
2017 Early Phase 1 NCT03048097 United States;
Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]_#1
Stanford University
2019 Phase 2 NCT04008069 United States;
Schisandra chinensis extract
Pusan National University Yangsan Hospital
2017 - NCT03402308 Korea, Republic of;
Seasonal influenza vaccine available for the 2012-2013 vaccine campaign
Assistance Publique - Hôpitaux de Paris
2012 Phase 3 NCT01687517 France;
Selexipag
ACTELION PHARMACEUTICALS LTD
2019 Phase 2;Phase 3 EUCTR2018-004887-74-IT Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Actelion
2021 Phase 2 NCT03942211 Belgium;Brazil;Canada;Czechia;France;Germany;Italy;Netherlands;Spain;United Kingdom;United States;
Sirolimus Ointment
Medical University of Vienna
2019 Phase 2 EUCTR2017-004930-27-AT Austria;
Skin biopsy
Kevin F. Gibson
2014 - NCT02134717 United States;
Tadalafil
University of North Carolina, Chapel Hill
2011 Phase 2/Phase 3 NCT01324999 United States;
Tofacitinib 5 mg twice daily
Yale University
2019 Phase 1 NCT03910543 United States;
Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Tofacitinib 5mg [Xeljanz] 1 year open-label extension
Oregon Health and Science University
2019 Phase 1 NCT03793439 United States;
Tracleer
Medical University of Vienna, Department of Clinical Pharmacology
2008 - EUCTR2007-005117-18-AT Austria;
St Georges Hospital
2007 Phase 4 EUCTR2006-005361-19-GB United Kingdom;
Tranilast
The First Affiliated Hospital with Nanjing Medical University
2018 Early Phase 1 NCT03528070 -
Uptravi
ACTELION PHARMACEUTICALS LTD
2019 Phase 2;Phase 3 EUCTR2018-004887-74-IT Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Actelion Pharmaceuticals Ltd
2020 Phase 2 EUCTR2018-004887-74-DE Belgium;Brazil;Canada;Czech Republic;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-PL Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-HU Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2;Phase 3 EUCTR2018-004887-74-ES Argentina;Belgium;Brazil;Canada;China;Czech Republic;Denmark;France;Germany;Hungary;India;Italy;Mexico;Netherlands;Poland;Portugal;Romania;Russian Federation;Spain;Sweden;Turkey;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-NL Belgium;Brazil;Canada;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004887-74-GB Belgium;Brazil;Canada;Czechia;France;Germany;Hungary;Italy;Netherlands;Poland;Spain;United Kingdom;United States;
Ustekinumab
CENTOCOR
2010 - EUCTR2009-010714-30-IT Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Centocor, Inc.
2009 Phase 2 NCT00955279 Belgium;Denmark;France;Germany;Netherlands;Norway;Romania;Sweden;United Kingdom;United States;
Ustekinumab liquid in prefilled syringe
Centocor BV
2009 Phase 2 EUCTR2009-010714-30-FR Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-NL Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
Janssen Biologics B.V.
2009 Phase 2 EUCTR2009-010714-30-GB Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-DK Belgium;Denmark;France;Germany;Italy;Netherlands;Romania;United Kingdom;United States;
2009 - EUCTR2009-010714-30-DE Belgium;Denmark;France;Germany;Italy;Netherlands;United Kingdom;
2009 - EUCTR2009-010714-30-BE Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;United Kingdom;United States;
Venipunctures
Kevin F. Gibson
2014 - NCT02134717 United States;
Water
Hokkaido University Graduate School of Medicine
2010 - JPRN-UMIN000006533 Japan;
[64]Cu Macrin
Ralph Weissleder, MD
2021 Phase 1 NCT04843891 United States;