1. Spinal and bulbar muscular atrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 18 / Drugs : 15 - (DrugBank : 8) / Drug target genes : 10 - Drug target pathways : 17
Drugs and their primary sponsors and trial info
Acetate
Department of Neurology, Nagoya University School of Medicine
2003 Phase 2 JPRN-UMIN000000474 Japan;
Department of NeurologyChiba University Graduate School of Medicine
2008 - JPRN-UMIN000001455 Japan;
BVS857
Novartis Farma SpA
2014 Phase 2 EUCTR2013-002608-15-IT Denmark;Germany;Italy;United States;
Novartis Pharma Services AG
2014 Phase 2 EUCTR2013-002608-15-DK Denmark;Germany;Italy;United States;
2014 Phase 2 EUCTR2013-002608-15-DE Denmark;Germany;Italy;United States;
Novartis Pharmaceuticals
2014 Phase 2 NCT02024932 Denmark;Germany;Italy;United States;
Clenbuterol
AZIENDA OSPEDALIERA DI PADOVA
2010 - EUCTR2010-022558-18-IT Italy;
Creatine
Department of Neurology, Nagoya University Graduate School of Medicine
2014 - JPRN-UMIN000012503 Japan;
Dutasteride
National Institute of Neurological Disorders and Stroke (NINDS)
2006 Phase 2 NCT00303446 United States;
Electrophysiologic study
Ramathibodi Hospital
2008 Phase 4 NCT00851461 Thailand;
Goserelin
Ramathibodi Hospital
2008 Phase 4 NCT00851461 Thailand;
Leuprolide
National Center for Research Resources (NCRR)
1992 Phase 2 NCT00004771 -
Leuprorelin
Department of Neurology, Nagoya University School of Medicine
2003 Phase 2 JPRN-UMIN000000474 Japan;
Department of NeurologyChiba University Graduate School of Medicine
2008 - JPRN-UMIN000001455 Japan;
Leuprorelin Acetate
TAKEDA PHARMACEUTICAL COMPANY LTD.
2017 - JPRN-JapicCTI-183981 -
Takeda
2017 - NCT03555578 Japan;
MONORES*30CPR 20MCG
AZIENDA OSPEDALIERA DI PADOVA
2010 - EUCTR2010-022558-18-IT Italy;
Mexiletine
Nagoya University Graduate School of Medicine
2017 Phase 2 JPRN-UMIN000026150 Japan;
TAP-144-SR(3M)
Gen Sobue
2007 Phase 3 JPRN-JMA-IIA00111 Japan;
JASMITT Clinical Trial Office
2012 Phase 2 JPRN-JMA-IIA00080 Japan;
2006 Phase 3 JPRN-JMA-IIA00009 Japan;
Testosterone
National Center for Research Resources (NCRR)
1992 Phase 2 NCT00004771 -
Tissue biopsy
Ramathibodi Hospital
2008 Phase 4 NCT00851461 Thailand;
Department of Neurology, Nagoya University School of Medicine
2003 Phase 2 JPRN-UMIN000000474 Japan;
Department of NeurologyChiba University Graduate School of Medicine
2008 - JPRN-UMIN000001455 Japan;
BVS857
Novartis Farma SpA
2014 Phase 2 EUCTR2013-002608-15-IT Denmark;Germany;Italy;United States;
Novartis Pharma Services AG
2014 Phase 2 EUCTR2013-002608-15-DK Denmark;Germany;Italy;United States;
2014 Phase 2 EUCTR2013-002608-15-DE Denmark;Germany;Italy;United States;
Novartis Pharmaceuticals
2014 Phase 2 NCT02024932 Denmark;Germany;Italy;United States;
Clenbuterol
AZIENDA OSPEDALIERA DI PADOVA
2010 - EUCTR2010-022558-18-IT Italy;
Creatine
Department of Neurology, Nagoya University Graduate School of Medicine
2014 - JPRN-UMIN000012503 Japan;
Dutasteride
National Institute of Neurological Disorders and Stroke (NINDS)
2006 Phase 2 NCT00303446 United States;
Electrophysiologic study
Ramathibodi Hospital
2008 Phase 4 NCT00851461 Thailand;
Goserelin
Ramathibodi Hospital
2008 Phase 4 NCT00851461 Thailand;
Leuprolide
National Center for Research Resources (NCRR)
1992 Phase 2 NCT00004771 -
Leuprorelin
Department of Neurology, Nagoya University School of Medicine
2003 Phase 2 JPRN-UMIN000000474 Japan;
Department of NeurologyChiba University Graduate School of Medicine
2008 - JPRN-UMIN000001455 Japan;
Leuprorelin Acetate
TAKEDA PHARMACEUTICAL COMPANY LTD.
2017 - JPRN-JapicCTI-183981 -
Takeda
2017 - NCT03555578 Japan;
MONORES*30CPR 20MCG
AZIENDA OSPEDALIERA DI PADOVA
2010 - EUCTR2010-022558-18-IT Italy;
Mexiletine
Nagoya University Graduate School of Medicine
2017 Phase 2 JPRN-UMIN000026150 Japan;
TAP-144-SR(3M)
Gen Sobue
2007 Phase 3 JPRN-JMA-IIA00111 Japan;
JASMITT Clinical Trial Office
2012 Phase 2 JPRN-JMA-IIA00080 Japan;
2006 Phase 3 JPRN-JMA-IIA00009 Japan;
Testosterone
National Center for Research Resources (NCRR)
1992 Phase 2 NCT00004771 -
Tissue biopsy
Ramathibodi Hospital
2008 Phase 4 NCT00851461 Thailand;