158. Tuberous sclerosis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 112 / Drugs : 71 - (DrugBank : 19) / Drug target genes : 35 - Drug target pathways : 118
Tuberous sclerosis and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
| ID | Diseases (Sorted by drug repositionability) |
|---|---|
| 158 | Tuberous sclerosis |
| 6 | Parkinson disease |
| 46 | Malignant rheumatoid arthritis |
| 13 | Multiple sclerosis/Neuromyelitis optica |
| 96 | Crohn disease |
| 97 | Ulcerative colitis |
| 2 | Amyotrophic lateral sclerosis |
| 36 | Epidermolysis bullosa |
| 22 | Moyamoya disease |
| 206 | Fragile X syndrome |
| 298 | Hereditary pancreatitis |
| 5 | Progressive supranuclear palsy |
| 145 | West syndrome |
| 152 | PCDH19 related syndrome |
| 34 | Neurofibromatosis |
| 70 | Spinal stenosis |
| 296 | Biliary atresia |
| 231 | Alpha-1-antitrypsin deficiency |
| 193 | Prader-Willi syndrome |
| 3 | Spinal muscular atrophy |
| 17 | Multiple system atrophy |
| 201 | Angelman syndrome |
| 8 | Huntington disease |
| 98 | Eosinophilic gastrointestinal disease |
| 75 | Cushing disease |
| 205 | Fragile X syndrome related disease |
| 18 | Spinocerebellar degeneration |
| 272 | Fibrodysplasia ossificans progressiva |
| 21 | Mitochondrial disease |
| 140 | Dorabe syndrome |
| 144 | Lennox-Gastaut syndrome |
| 156 | Rett syndrome |
| 84 | Sarcoidosis |
| 155 | Acquired aphasia with convulsive disorder |
| 299 | Cystic fibrosis |
| 49 | Systemic lupus erythematosus |
| 113 | Muscular dystrophy |
| 65 | Primary immunodeficiency |
| 302 | Leber hereditary optic neuropathy |
| 157 | Sturge-Weber syndrome |
| 226 | Interstitial cystitis with Hunners ulcer |
| 11 | Myasthenia gravis |
| 151 | Rasmussen encephalitis |
| 51 | Scleroderma |
| 222 | Primary nephrotic syndrome |
| 227 | Osler disease |
| 60 | Aplastic anemia |
| 85 | Idiopathic interstitial pneumonia |
| 58 | Hypertrophic cardiomyopathy |
| 285 | Fanconi anemia |
| 95 | Autoimmune hepatitis |
| 286 | Hereditary sideroblastic anemia |
| 228 | Bronchiolitis obliterans |
| 278 | Huge lymphatic malformation with cervicofacial lesion |
| 66 | IgA nephropathy |
| 326 | Osteopetrosis |
| 107 | Juvenile idiopathic arthritis |
| 283 | Acquired pure red cell aplasia |
| 160 | Congenital ichthyosis |
| 39 | Toxic epidermal necrolysis |
| 162 | Pemphigoid |
| 28 | Systemic amyloidosis |
| 55 | Relapsing polychondritis |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) |
| 56 | Behcet disease |
| 62 | Paroxysmal nocturnal hemoglobinuria |
| 20 | Adrenoleukodystrophy |
| 86 | Pulmonary arterial hypertension |
| 63 | Idiopathic thrombocytopenic purpura |
| 274 | Osteogenesis Imperfecta |
| 61 | Autoimmune hemolytic anemia |
| 50 | Dermatomyositis |
| 38 | Stevens-Johnson syndrome |
| 269 | Pyogenic arthritis |
| 224 | Purpura nephritis |
| 53 | Sjogren syndrome |
| 64 | Thrombotic thrombocytopenic purpura |
| 77 | Growth hormone secreting pituitary adenoma |
| 337 | Homocystinuria |
| 19 | Lysosomal storage disease |
| 41 | Giant cell arteritis |
| 164 | Oculocutaneous albinism |
| 45 | Eosinophilic granulomatosis with Polyangiitis |
| 93 | Primary biliary cholangitis |
| 26 | HTLV-1-associated myelopathy |
| 271 | Ankylosing spondylitis |
| 284 | Diamond-Blackfan anemia |
| 90 | Retinitis pigmentosa |
| 40 | Takayasu arteritis |
| 42 | Polyarteritis nodosa |
| 89 | Lymphangioleiomyomatosis |
| 225 | Congenital nephrogenic diabetes insipidus |
| 256 | Muscle glycogenosis |
| 67 | Polycystic kidney disease |
| 127 | Frontotemporal lobar degeneration |
| 169 | Menkes disease |
| 170 | Occipital horn syndrome |
| 167 | Marfan syndrome |
| 251 | Urea cycle disorder |
| 233 | Wolfram syndrome |
| 192 | Cockayne syndrome |
| 277 | Lymphangiomatosis |
| 281 | Klippel-Trenaunay-Weber syndrome |
| 111 | Congenital myopathy |
| 137 | Focal cortical dysplasia |