DR info

Clinical trials : 93 / Drugs : 77 - (DrugBank : 8) / Drug target genes : 10 - Drug target pathways : 36

Alpha-1-antitrypsin deficiency and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
231	Alpha-1-antitrypsin deficiency
6	Parkinson disease
97	Ulcerative colitis
13	Multiple sclerosis/Neuromyelitis optica
70	Spinal stenosis
96	Crohn disease
298	Hereditary pancreatitis
46	Malignant rheumatoid arthritis
2	Amyotrophic lateral sclerosis
36	Epidermolysis bullosa
34	Neurofibromatosis
140	Dorabe syndrome
22	Moyamoya disease
144	Lennox-Gastaut syndrome
193	Prader-Willi syndrome
152	PCDH19 related syndrome
158	Tuberous sclerosis
156	Rett syndrome
84	Sarcoidosis
8	Huntington disease
201	Angelman syndrome
3	Spinal muscular atrophy
75	Cushing disease
205	Fragile X syndrome related disease
5	Progressive supranuclear palsy
296	Biliary atresia
272	Fibrodysplasia ossificans progressiva
21	Mitochondrial disease
145	West syndrome
206	Fragile X syndrome
155	Acquired aphasia with convulsive disorder
98	Eosinophilic gastrointestinal disease
17	Multiple system atrophy
18	Spinocerebellar degeneration
10	Charcot-Marie-Tooth disease
107	Juvenile idiopathic arthritis
1	Spinal and bulbar muscular atrophy
226	Interstitial cystitis with Hunners ulcer
256	Muscle glycogenosis
168	Ehlers-Danlos syndrome
86	Pulmonary arterial hypertension
51	Scleroderma
113	Muscular dystrophy
58	Hypertrophic cardiomyopathy
38	Stevens-Johnson syndrome
53	Sjogren syndrome
337	Homocystinuria
114	Non-dystrophic myotonia syndrome
28	Systemic amyloidosis
127	Frontotemporal lobar degeneration
251	Urea cycle disorder
111	Congenital myopathy