274. Osteogenesis Imperfecta Disease details / Clinical trials / Drug dev / DR info


Clinical trials : 91 Drugs : 101 - (DrugBank : 20) / Drug target genes : 11 - Drug target pathways : 48

Drugs and their primary sponsors and trial info
00244301   
   AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
      2015   Phase 2   EUCTR2015-002622-39-IT   Italy;
ACLASTA   
   Schriners Hospitals for Children
      2012   -   EUCTR2011-000745-21-BE   Belgium;Canada;United States;
AMG 162   
   AMGEN INC.
      2019   Phase 3   EUCTR2018-000550-21-IT   Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2014-000184-40-IT   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
   Amgen Inc
      2020   Phase 3   EUCTR2018-000550-21-DE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2020   Phase 3   EUCTR2018-000550-21-CZ   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2020   Phase 3   EUCTR2018-000550-21-BG   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2019   Phase 3   EUCTR2018-000550-21-GB   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2019   Phase 3   EUCTR2018-000550-21-ES   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2018   Phase 3   EUCTR2018-000550-21-HU   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2018-000550-21-PL   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2018-000550-21-FR   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2018-000550-21-BE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
   Amgen Inc.
      2015   Phase 3   EUCTR2014-000184-40-BE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   -   EUCTR2014-000184-40-Outside-EU/EEA   Australia;Canada;United States;
   Amgen, Inc.
      2020   Phase 3   EUCTR2014-000184-40-PL   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   EUCTR2014-000184-40-GB   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-HU   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-ES   Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-DE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-CZ   Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2014-000184-40-FR   Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2014-000184-40-BG   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
AMG 785   
   AMGEN INC.
      2020   Phase 1   EUCTR2017-004972-74-IT   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
   Amgen Inc.
      2021   Phase 1   EUCTR2017-004972-74-GR   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
      2021   Phase 1   EUCTR2017-004972-74-DE   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
      2020   Phase 1   EUCTR2017-004972-74-HU   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
ANTI-SCLEROSTIN MONOCLONAL ANTIBODY   
   Mereo BioPharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-DK   Canada;Denmark;France;United Kingdom;United States;
   Mereo Biopharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-GB   Canada;Denmark;France;United Kingdom;United States;
      2017   Phase 2   EUCTR2016-005096-27-FR   Canada;Denmark;France;United Kingdom;United States;
Aclasta   
   Bente Langdahl, consultant, ass. professor, PhD, DMSc
      2011   Phase 2   EUCTR2011-002811-27-DK   Denmark;
Actonel 5mg Film Coated Tablets   
   Sheffield Children's NHS Foundation Trust
      2017   Phase 2   EUCTR2016-003606-14-GB   United Kingdom;
Actonel Once a Week 35 mg film-coated tablets   
   Sheffield Children's NHS Foundation Trust
      2017   Phase 2   EUCTR2016-003606-14-GB   United Kingdom;
Actonel/Optinate 5mg film-coated tablets   
   Procter & Gamble Ltd
      2006   -   EUCTR2004-000485-13-FI   Czech Republic;Denmark;Finland;Hungary;Spain;
Alendronate   
   Indiana University School of Medicine
      1999   Phase 4   NCT00159419   United States;
   Peking Union Medical College Hospital
      2007   Phase 4   NCT02303873   -
   Tohoku University School of Medicine, Department of Pediatrics
      2013   -   JPRN-UMIN000010615   Japan;
Alendronic acid   
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Alternative osteoporosis medications   
   Amgen
      2018   Phase 3   NCT03638128   Australia;Belgium;Canada;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
Anti-sclerostin monoclonal antibody   
   Novartis Pharma Services AG
      2012   -   EUCTR2011-001465-41-DE   Canada;Germany;
      2011   Phase 1;Phase 2   EUCTR2011-001465-41-BE   Belgium;Canada;Germany;
BOOST cells   
   Christian Medical College, Vellore, India
      2019   Phase 1/Phase 2   NCT04623606   India;
   Karolinska Institutet
      2019   Phase 1/Phase 2   NCT03706482   Sweden;
      2018   Phase 1;Phase 2   EUCTR2015-003699-60-SE   Sweden;
BPS804   
   Mereo BioPharma
      2017   Phase 2   NCT03216486   United States;
   Mereo BioPharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-DK   Canada;Denmark;France;United Kingdom;United States;
   Mereo Biopharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-GB   Canada;Denmark;France;United Kingdom;United States;
      2017   Phase 2   EUCTR2016-005096-27-FR   Canada;Denmark;France;United Kingdom;United States;
   Novartis Pharma Services AG
      2012   -   EUCTR2011-001465-41-DE   Canada;Germany;
      2011   Phase 1;Phase 2   EUCTR2011-001465-41-BE   Belgium;Canada;Germany;
   Ultragenyx Pharmaceutical Inc
      2017   Phase 2   NCT03118570   Canada;Denmark;France;United Kingdom;United States;
      2011   Phase 2   NCT01417091   Belgium;Canada;Germany;United States;
Bisphosphonates   
   Luca Sangiorgi
      2013   -   NCT04115774   Italy;
Blood sample   
   Hospices Civils de Lyon
      2019   -   NCT04009733   France;
Bone marrow transplant   
   St. Jude Children's Research Hospital
      2004   -   NCT00187018   United States;
Bonefos   
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Busulfan   
   St. Jude Children's Research Hospital
      1995   Phase 1   NCT00705120   United States;
CALCIO CARBONATO/COLECALCIFEROLO   
   AMGEN INC.
      2020   Phase 1   EUCTR2017-004972-74-IT   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
CALCIUM D3 SANDOZ - 1000 MG + 880 U.I. COMPRESSE EFFERVESCENTI 30 COMPRESSE DIVISIBILI   
   AMGEN INC.
      2020   Phase 1   EUCTR2017-004972-74-IT   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Calcichew D3   
   University of Edinburgh
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
Calcichew tablets   
   Sheffield Children's NHS Foundation Trust
      2017   Phase 2   NCT03208582   United Kingdom;
Calcium   
   Amgen
      2021   Phase 1   NCT04545554   Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
Celulas madre mesenquimales troncales adultas alogenicas de médula ósea no expandida   
   Itziar Astigarraga Aguirre
      2013   -   EUCTR2012-002553-38-ES   Spain;
Clasteon   
   University of Edinburgh
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
Cyclophosphamide   
   St. Jude Children's Research Hospital
      1995   Phase 1   NCT00705120   United States;
Cyclosporin   
   St. Jude Children's Research Hospital
      1995   Phase 1   NCT00705120   United States;
Células mesenquimales troncales adultas alogénicas de médula ósea no expandidas(ref cruzada PEI nº 12-088)   
   Itziar Astigarraga Aguirre
      2013   -   EUCTR2012-002553-38-ES   Spain;
Denosumab   
   Amgen
      2018   Phase 3   NCT03638128   Australia;Belgium;Canada;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   NCT02352753   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
   University of Cologne
      2013   Phase 2   NCT01799798   Germany;
Denosumab - - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand   
   Amgen Inc.
      -   -   EUCTR2014-000184-40-Outside-EU/EEA   Australia;Canada;United States;
Denosumab - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand   
   AMGEN INC.
      2019   Phase 3   EUCTR2018-000550-21-IT   Austria;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2014-000184-40-IT   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
   Amgen Inc
      2020   Phase 3   EUCTR2018-000550-21-DE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2020   Phase 3   EUCTR2018-000550-21-CZ   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2020   Phase 3   EUCTR2018-000550-21-BG   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2019   Phase 3   EUCTR2018-000550-21-GB   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2019   Phase 3   EUCTR2018-000550-21-ES   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2018   Phase 3   EUCTR2018-000550-21-HU   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2018-000550-21-PL   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2018-000550-21-FR   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2018-000550-21-BE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
   Amgen Inc.
      2015   Phase 3   EUCTR2014-000184-40-BE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
   Amgen, Inc.
      2020   Phase 3   EUCTR2014-000184-40-PL   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2015   Phase 3   EUCTR2014-000184-40-GB   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-HU   Australia;Belgium;Bulgaria;Canada;Czech Republic;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-ES   Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-DE   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
      2014   Phase 3   EUCTR2014-000184-40-CZ   Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2014-000184-40-FR   Australia;Belgium;Bulgaria;Canada;Czech Republic;Finland;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
      -   Phase 3   EUCTR2014-000184-40-BG   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Poland;Spain;United Kingdom;United States;
Denusomab   
   University of Cologne
      2013   -   EUCTR2012-002887-29-DE   Germany;
Disodium Pamidronate 15mg (15mg strength)   
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Evenity   
   AMGEN INC.
      2020   Phase 1   EUCTR2017-004972-74-IT   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
Expanded human first trimester fetal liver-derived mesenchymal stem cells   
   Karolinska Institutet
      2018   Phase 1;Phase 2   EUCTR2015-003699-60-SE   Sweden;
Forsteo   
   Bente Langdahl, consultant, ass. professor, PhD, DMSc
      2011   Phase 2   EUCTR2011-002811-27-DK   Denmark;
Fresolimumab   
   Baylor College of Medicine
      2017   Phase 1   NCT03064074   United States;
Fultium-D3 800IU capsules   
   University of Edinburgh
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
GENOTROPIN*1TBF 5,3MG (16UI)   
   AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
      2005   -   EUCTR2004-005275-42-IT   Italy;
H05AA02   
   Bente Langdahl, consultant, ass. professor, PhD, DMSc
      2011   Phase 2   EUCTR2011-002811-27-DK   Denmark;
High-dose vitamin D (2000 IU per day)   
   Louis-Nicolas Veilleux Ph.D.
      2012   Phase 4   NCT01713231   Canada;
Humatrope   
   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
      1991   Phase 3   NCT00001305   United States;
Ibandronic acid   
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Mesenchymal Stem Cell Transplantation   
   St. Jude Children's Research Hospital
      1995   Phase 1   NCT00705120   United States;
Mesenchymal Stem Cells   
   Hospital de Cruces
      2014   Phase 1   NCT02172885   Spain;
Mesenchymal Stromal Cells   
   Nationwide Children's Hospital
      2010   Phase 1   NCT01061099   United States;
NERIXIA*INFUS IV CONC 2F   
   AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
      2005   -   EUCTR2004-005275-42-IT   Italy;
Optinate 5 mg filmcoated tablets   
   Procter & Gamble Ltd
      2007   -   EUCTR2004-000485-13-DK   Czech Republic;Denmark;Finland;Hungary;Spain;
PLASMASAFE - SOLUZIONE PER INFUSIONE 1 SACCA DA 200 ML   
   AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA
      2015   Phase 2   EUCTR2015-002622-39-IT   Italy;
Pamidronate   
   Indiana University School of Medicine
      1999   Phase 4   NCT00159419   United States;
   Kobe University Hospital
      2018   -   JPRN-UMIN000031290   Japan;
   University of New Mexico
      2007   -   NCT00655681   United States;
Pamidronate (Aredia)   
   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
      2000   Phase 3   NCT00005901   Canada;United States;
Prolia   
   University of Cologne
      2013   -   EUCTR2012-002887-29-DE   Germany;
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Risedronate Oral Tablet   
   Hospital for Special Surgery, New York
      2019   Phase 4   NCT04152551   United States;
Risedronate Sodium   
   Sheffield Children's NHS Foundation Trust
      2017   Phase 2   NCT03208582   United Kingdom;
      2017   Phase 2   EUCTR2016-003606-14-GB   United Kingdom;
Risedronate sodium   
   Procter & Gamble Ltd
      2007   -   EUCTR2004-000485-13-DK   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-HU   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-FI   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-CZ   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-BE   Belgium;Czech Republic;Denmark;Finland;Hungary;Spain;
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Risedronate sodium (Actonel)   
   Warner Chilcott
      2004   Phase 3   NCT00106028   Australia;Belgium;Chile;Czech Republic;Finland;Germany;Hungary;Italy;Poland;South Africa;Spain;United Kingdom;United States;
Risedronato sódico   
   Procter & Gamble Ltd
      2006   -   EUCTR2004-000485-13-ES   Czech Republic;Denmark;Finland;Hungary;Spain;
Risedronic acid   
   Procter & Gamble Ltd
      2007   -   EUCTR2004-000485-13-DK   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-HU   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-FI   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-CZ   Czech Republic;Denmark;Finland;Hungary;Spain;
      2006   -   EUCTR2004-000485-13-BE   Belgium;Czech Republic;Denmark;Finland;Hungary;Spain;
Romosozumab   
   Amgen
      2021   Phase 1   NCT04545554   Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
SAR439459   
   Sanofi
      2022   Phase 1   NCT05231668   -
Setrusumab   
   Mereo BioPharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-DK   Canada;Denmark;France;United Kingdom;United States;
   Mereo Biopharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-GB   Canada;Denmark;France;United Kingdom;United States;
   Ultragenyx Pharmaceutical Inc
      2022   Phase 2/Phase 3   NCT05125809   Australia;Canada;Denmark;Italy;United Kingdom;United States;
Somatropin   
   AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
      2005   -   EUCTR2004-005275-42-IT   Italy;
Standard-dose vitamin D (400IU per day)   
   Louis-Nicolas Veilleux Ph.D.
      2012   Phase 4   NCT01713231   Canada;
Teriparatide   
   University of Aarhus
      2012   Phase 2   NCT01679080   Denmark;
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Teriparatide (FORTEO)   
   Oregon Health and Science University
      2005   Phase 4   NCT00131469   United States;
Teriparatide Pen Injector   
   University of Edinburgh
      2016   Phase 4   NCT03735537   Ireland;United Kingdom;
VARI   
   AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
      2005   -   EUCTR2004-005275-42-IT   Italy;
Vitamin D   
   Amgen
      2021   Phase 1   NCT04545554   Germany;Greece;Hungary;Italy;Spain;Turkey;United States;
Vitamina D e calcio   
   AMGEN INC.
      2020   Phase 1   EUCTR2017-004972-74-IT   France;Germany;Greece;Hungary;Italy;Spain;Turkey;
XGEVA - 120 MG - SOLUZIONE INIETTABILE - USO SOTTOCUTANEO - FLACONCINO (VETRO) - 1.7 ML 4 FLACONCINI   
   AMGEN INC.
      -   Phase 3   EUCTR2014-000184-40-IT   Australia;Belgium;Bulgaria;Canada;Czech Republic;Czechia;France;Germany;Hungary;Italy;Poland;Spain;United Kingdom;United States;
ZOL446   
   Novartis Pharma AG
      2005   -   EUCTR2004-001666-40-HU   Hungary;United Kingdom;
      2005   -   EUCTR2004-001666-40-GB   Hungary;United Kingdom;
      -   Phase 2   EUCTR2004-001666-40-BE   Belgium;Hungary;United Kingdom;
Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion, generic medicinal product.   
   Mereo BioPharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-DK   Canada;Denmark;France;United Kingdom;United States;
   Mereo Biopharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-GB   Canada;Denmark;France;United Kingdom;United States;
Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion,generic medicinal product   
   Mereo BioPharma 3 Ltd.
      2017   Phase 2   EUCTR2016-005096-27-DK   Canada;Denmark;France;United Kingdom;United States;
Zoledronic acid   
   Novartis Pharma AG
      2005   -   EUCTR2004-001666-40-HU   Hungary;United Kingdom;
      2005   -   EUCTR2004-001666-40-GB   Hungary;United Kingdom;
      -   Phase 2   EUCTR2004-001666-40-BE   Belgium;Hungary;United Kingdom;
   Schriners Hospitals for Children
      2012   -   EUCTR2011-000745-21-BE   Belgium;Canada;United States;
   University of Aarhus
      2012   Phase 2   NCT01679080   Denmark;
   University of Edinburgh
      2021   Phase 4   EUCTR2016-003228-22-NL   Ireland;Netherlands;United Kingdom;
      2017   Phase 4   EUCTR2016-003228-22-IE   Ireland;Netherlands;United Kingdom;
      2016   Phase 4   EUCTR2016-003228-22-GB   Ireland;United Kingdom;
Zometa   
   Novartis
      -   -   EUCTR2015-003539-37-Outside-EU/EEA   United States;
Ácido risedrónico   
   Procter & Gamble Ltd
      2006   -   EUCTR2004-000485-13-ES   Czech Republic;Denmark;Finland;Hungary;Spain;