298. Hereditary pancreatitis Disease details / Clinical trials / Drug dev / DR info


Clinical trials : 95 Drugs : 148 - (DrugBank : 51) / Drug target genes : 53 - Drug target pathways : 142

Drugs and their primary sponsors and trial info
A04AD10   
   Radboud University Nijmegen Medical Centre
      2012   Phase 2   EUCTR2012-000730-19-NL   Netherlands;
      2011   -   EUCTR2011-000647-24-NL   Netherlands;
ANTOX (vers) 1.2   
   University of Liverpool
      2008   Phase 3   EUCTR2006-000087-83-GB   United Kingdom;
ANTOX (vers.)1.2   
   University Medicine Greifswald
      2005   Phase 3   NCT00142233   Germany;
Acetyl-L-carnitine 1000mg 2X per day for 3 months   
   Karin High
      2015   Early Phase 1   NCT02538146   United States;
Alcohol   
   Changhai Hospital
      2011   -   NCT04574297   -
Amino acids   
   Tohoku University Hospital
      2010   -   JPRN-UMIN000003020   Japan;
Amlodipine (drug)   
   University of Pittsburgh
      2005   Phase 1/Phase 2   NCT00156403   United States;
Analgesics   
   Changhai Hospital
      2016   -   NCT02971475   China;
Antioxidant plus Pregabalin   
   Asian Institute of Gastroenterology, India
      2012   -   NCT01528540   India;
Antioxidants   
   All India Institute of Medical Sciences, New Delhi
      2003   Phase 3   NCT00319358   India;
Antox version 1.2   
   Pharmanord, UK, LTD
      2007   Phase 2   EUCTR2006-006958-10-GB   United Kingdom;
Autologous mesenchymal stromal cell   
   Medical University of South Carolina
      2014   Phase 1   NCT02384018   United States;
Benzoyl-L-tyrosyl-[1-13C]alanine (Bz-Tyr-Ala)   
   Exalenz Bioscience LTD.
      2009   Phase 2   NCT01259544   India;
Bone marrow-derived mesenchymal stem cells   
   Medical University of South Carolina
      2021   Phase 1   NCT05095532   United States;
Bupivicaine alone   
   The Cleveland Clinic
      2008   Phase 3   NCT00658736   United States;
CREON   
   AbbVie
      2021   Phase 4   NCT05069597   United States;
      2021   -   NCT04949828   United States;
      2020   Phase 4   NCT04315311   United States;
Calcium, Dietary   
   Hvidovre University Hospital
      2009   -   NCT01141998   Denmark;
Carbon monoxide   
   Medical University of South Carolina
      2015   Phase 1/Phase 2   NCT02567240   United States;
Celiac Block with triamcinolone and bupivicaine   
   University of Southern California
      2014   -   NCT02399800   United States;
Cholecalciferol   
   Hvidovre University Hospital
      2009   -   NCT01141998   Denmark;
Creon   
   Hospital Avicenne
      2004   Phase 4   NCT00957151   France;
   Institut National de la Recherche Agronomique
      2005   -   NCT01154608   France;
Creon 10000   
   Solvay Pharmaceuticals GmbH
      2008   -   EUCTR2007-004004-12-BG   Bulgaria;
Creon 25000   
   Department of gastroenterology. University Hospital of Santiago
      2016   -   EUCTR2015-002570-20-ES   Spain;
   Solvay Pharmaceuticals GmbH
      2008   -   EUCTR2007-004004-12-BG   Bulgaria;
Creon36™   
   Children's Hospital of Philadelphia
      2016   Phase 2   NCT02849704   United States;
Diazepam   
   Radboud University
      2011   Phase 2   NCT01318369   Netherlands;
ERCP with Bupivacaine infusion   
   Johns Hopkins University
      2021   Early Phase 1   NCT04611958   United States;
EUR-1008 (APT-1008) High Dose   
   Forest Laboratories
      2008   Phase 3   NCT00788593   Italy;Ukraine;United States;
EUR-1008 (APT-1008) Low Dose   
   Forest Laboratories
      2008   Phase 3   NCT00788593   Italy;Ukraine;United States;
EUR-1066-A   
   Forest Laboratories
      2010   Phase 1   NCT01159119   United States;
EUR-1066-B   
   Forest Laboratories
      2010   Phase 1   NCT01159119   United States;
EUS procedure with drug injection   
   Centre hospitalier de l'Université de Montréal (CHUM)
      2011   Phase 3   NCT01318590   Belgium;Canada;
Endoscopic drainage of the main pancreatic duct   
   Changhai Hospital
      2016   -   NCT02971475   China;
Ensure Surgical   
   Ohio State University
      2017   -   NCT03244683   United States;
Etanercept   
   University of Minnesota
      2016   Phase 4   NCT02713997   United States;
Extracorporeal shock wave lithotripsy   
   Changhai Hospital
      2016   -   NCT02971475   China;
Extracorporeal shock wave lithotripsy and endoscopic drainage of the main pancreatic duct   
   Changhai Hospital
      2022   -   NCT05261997   China;
FLUIMUCIL*20CPR EFF   
   POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
      2012   -   EUCTR2012-004170-26-IT   Italy;
Gabapentin prescriptions   
   GlaxoSmithKline
      2010   -   NCT01236053   -
      2010   -   NCT01138124   -
Gold   
   The First Affiliated Hospital of the Naval Medical University of the Chinese People's Liberation Army
      2020   Phase 0   ChiCTR2000037002   China;
Helopanflat Mono®   
   Berlin-Chemie AG
      2005   -   EUCTR2005-000736-24-DE   Germany;
Hemoglobin   
   University of Nebraska
      2018   -   NCT03568630   United States;
Hydroxychloroquine   
   The Cleveland Clinic
      2017   Phase 2   NCT03283566   United States;
Indomethacin   
   Mayo Clinic
      2020   Phase 2   NCT04207060   United States;
Intra Plexus Triamcinolone and Bupivicaine Injection   
   University of Southern California
      2014   -   NCT02399800   United States;
Kreon 25000   
   Department of gastroenterology. University Hospital of Santiago
      2016   -   EUCTR2015-002570-20-ES   Spain;
LANREOTIDE ACETATE   
   Erasme hospital
      2010   -   EUCTR2009-016082-29-BE   Belgium;
LIPASE   
   Erasmus MC
      2011   -   EUCTR2010-020303-69-NL   Netherlands;
Liprotamase   
   Anthera Pharmaceuticals
      2007   Phase 3   NCT00500084   United States;
Lyrica   
   Department of Medical Gastroenterology
      2008   Phase 3   EUCTR2008-002671-27-DK   Denmark;
Lyrica®   
   Afdeling heelkunde, Universitair Medisch Centrum Sint Radboud
      2009   -   EUCTR2009-010266-28-NL   Netherlands;
MS1819   
   Laboratoires Mayoly Spindler
      2010   -   EUCTR2010-018900-10-FR   France;
MS1819-SD   
   AzurRx SAS
      2017   Phase 2   NCT03481803   Australia;France;New Zealand;
Magnesiocard 2.5mmol   
   University of Liverpool
      2008   Phase 3   EUCTR2006-000087-83-GB   United Kingdom;
Magnesium   
   University Medicine Greifswald
      2005   Phase 3   NCT00142233   Germany;
Mayo Interactive Breath Hold Monitor   
   Mayo Clinic
      2006   -   NCT00588367   United States;
Mezym F   
   Berlin-Chemie AG
      2010   -   EUCTR2005-000562-38-DE   Germany;
Midazolam   
   Prof. Asbjørn Mohr Drewes
      2013   Phase 4   EUCTR2013-003357-17-DK   Denmark;
Morphine, buprenorphine, pethidine, tramaldol, metamizole and acetylsalicylacid (Analgesics)   
   Changhai Hospital
      2022   -   NCT05270434   China;
Multienzymes (lipase, protease etc.)   
   EURAND SPA
      2008   -   EUCTR2008-000061-37-IT   Italy;
NI-03   
   Kangen Pharmaceuticals, Inc
      2015   Phase 1/Phase 2   NCT02693093   Russian Federation;Ukraine;United States;
Namisol   
   Radboud University
      2011   Phase 2   NCT01318369   Netherlands;
   Radboud University Nijmegen Medical Centre
      2012   Phase 2   EUCTR2012-000730-19-NL   Netherlands;
      2011   -   EUCTR2011-000647-24-NL   Netherlands;
Nexium (esomeprazole magnesium)   
   University of Florida
      2009   Phase 1   NCT01142128   United States;
OXYCODONE HYDROCHLORIDE   
   Mech-Sense, Dept. Gastroenterology & Hepatology, Aalborg University Hospital
      2017   Phase 1;Phase 4   EUCTR2017-000732-34-DK   Denmark;
Omeprazole   
   Forest Laboratories
      2007   Phase 3   NCT00559364   Canada;Germany;Poland;Slovakia;United States;
Oxycodone Depot ”Sandoz”, depot tablets   
   Mech-Sense, Dept. Gastroenterology & Hepatology, Aalborg University Hospital
      2017   Phase 1;Phase 4   EUCTR2017-000732-34-DK   Denmark;
Oxycodonhydrochlorid ”Lannacher”, depot tablets   
   Mech-Sense, Dept. Gastroenterology & Hepatology, Aalborg University Hospital
      2017   Phase 1;Phase 4   EUCTR2017-000732-34-DK   Denmark;
Oxynorm   
   Mech-Sense, Dept. Gastroenterology & Hepatology, Aalborg University Hospital
      2017   Phase 1;Phase 4   EUCTR2017-000732-34-DK   Denmark;
PFD   
   Yokohama City University
      2017   -   JPRN-UMIN000028150   Japan;
   the Department of Diagnostic Radiology Kawasaki Medical School
      2012   -   JPRN-UMIN000008340   Japan;
PL 00512/0150   
   Department of gastroenterology. University Hospital of Santiago
      2016   -   EUCTR2015-002570-20-ES   Spain;
Pancreatic enzyme(Pancreatin Enteric-coated Capsules or Oryz-Aspergillus Enzyme and Pancreatin Table), antidiabetic medicine(Acarbose Tablets, Glucophage, Glimepirde Tablets)   
   Changhai Hospital
      2022   -   NCT05261997   China;
Pancreatic enzymes   
   Erasmus MC
      2011   -   EUCTR2010-020303-69-NL   Netherlands;
Pancreatin   
   Abbott Products
      2008   Phase 3   NCT00705978   India;
   Axcan Pharma S.A.
      2004   -   EUCTR2004-002468-89-DE   Germany;
   Berlin-Chemie AG
      2010   -   EUCTR2005-000562-38-DE   Germany;
      2005   -   EUCTR2005-000736-24-DE   Germany;
Pancrelipase   
   Dartmouth-Hitchcock Medical Center
      2016   Phase 2   NCT02706236   United States;
   Department of Internal Medicine Second Teaching Hospital Fujita Health University School of Medicine
      2012   -   JPRN-UMIN000009547   Japan;
   Digestive Care, Inc.
      2008   Phase 4   NCT00744250   United States;
   Fukushima Medical University Aizu Medical Center
      2013   -   JPRN-UMIN000013182   Japan;
Pancrelipase Delayed Release Capsule   
   Solvay Pharmaceuticals GmbH
      2008   -   EUCTR2007-004004-12-BG   Bulgaria;
Pancrelipase delayed release capsule   
   Solvay Pharmaceuticals
      2007   Phase 3   NCT00414908   Bulgaria;Former Serbia and Montenegro;Poland;Puerto Rico;Russian Federation;Serbia;South Africa;Ukraine;United States;
Pancrelipase/Pancreas Powder   
   Solvay Pharmaceuticals GmbH
      2008   -   EUCTR2007-004004-12-BG   Bulgaria;
Panzytrat   
   Erasmus MC
      2011   -   EUCTR2010-020303-69-NL   Netherlands;
Panzytrat 25.000   
   Axcan Pharma S.A.
      2004   -   EUCTR2004-002468-89-DE   Germany;
Panzytrat 25.000 FIP-E units of Lipase   
   Foundation for Liver Research
      2011   Phase 4   NCT01430234   Netherlands;
Pentoxifylline   
   Mayo Clinic
      2015   Phase 3   NCT02487225   United States;
Perflubutane   
   Department of EndoscopyThe Jikei University School of Medicine
      2018   -   JPRN-UMIN000030735   Japan;
Pioglitazone   
   University of Michigan
      2008   Phase 2   NCT00782795   United States;
Pregabalin   
   Aalborg Universitetshospital
      2008   Phase 2/Phase 3   NCT00755573   Denmark;Netherlands;
   Department of Medical Gastroenterology
      2008   Phase 3   EUCTR2008-002671-27-DK   Denmark;
Prolastin-C   
   Medical University of South Carolina
      2016   Phase 1/Phase 2   NCT02947087   United States;
Proton pump inhibitor (PPI)   
   Forest Laboratories
      2007   Phase 3   NCT00559364   Canada;Germany;Poland;Slovakia;United States;
REGN475/SAR164877   
   Regeneron Pharmaceuticals
      2009   Phase 2   NCT01001923   United States;
RG1068 (Synthetic Human Secretin)   
   Massachusetts General Hospital
      2008   Phase 1   NCT00621283   United States;
      2008   Phase 1   NCT00620919   United States;
RVG 13760   
   Erasmus MC
      2011   -   EUCTR2010-020303-69-NL   Netherlands;
Recombinant Microbial Lipase SLV339   
   Solvay Pharmaceuticals
      2008   Phase 2   NCT00630279   Czech Republic;Denmark;Hungary;Latvia;Poland;Russian Federation;Sweden;
Recombinant microbial lipase   
   Solvay Pharmaceuticals GmbH
      2008   -   EUCTR2007-000375-42-LV   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2008   -   EUCTR2007-000375-42-HU   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2008   -   EUCTR2007-000375-42-DK   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2008   -   EUCTR2007-000375-42-CZ   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2007   -   EUCTR2007-000375-42-SE   Czech Republic;Denmark;Hungary;Latvia;Sweden;
Reparixin   
   Dompé Farmaceutici S.p.A
      2014   Phase 2/Phase 3   NCT01967888   Canada;United States;
SA-001   
   Abbott
      2008   Phase 3   NCT00401076   Japan;
      2007   Phase 3   NCT00400842   Japan;
SLV339   
   Solvay Pharmaceuticals GmbH
      2008   -   EUCTR2007-000375-42-LV   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2008   -   EUCTR2007-000375-42-HU   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2008   -   EUCTR2007-000375-42-DK   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2008   -   EUCTR2007-000375-42-CZ   Czech Republic;Denmark;Hungary;Latvia;Sweden;
      2007   -   EUCTR2007-000375-42-SE   Czech Republic;Denmark;Hungary;Latvia;Sweden;
Secretin   
   Children's Hospital Medical Center, Cincinnati
      2016   -   NCT02869893   United States;
   University of Nottingham
      2012   Phase 1/Phase 2   NCT02458118   United Kingdom;
      2010   Phase 1   NCT01452217   United Kingdom;
Simvastatin   
   National Cancer Institute (NCI)
      2016   Phase 2   NCT02743364   United States;
Somatuline Autogel   
   Erasme hospital
      2010   -   EUCTR2009-016082-29-BE   Belgium;
Soy bread   
   Ohio State University
      2015   -   NCT02577640   United States;
Tanezumab   
   Pfizer
      2010   Phase 2   NCT01146561   United States;
Tetrahydro-6,6,9-tri methyl-3-penthyl-6 H-dibenzo[ b,d ]pyran-1-ol   
   Radboud University Nijmegen Medical Centre
      2012   Phase 2   EUCTR2012-000730-19-NL   Netherlands;
Tetrahydrocannabinol   
   Radboud University
      2012   Phase 2   NCT01551511   Netherlands;
Thalidomide   
   Winthrop University Hospital
      2005   Phase 2   NCT00469703   United States;
Time interval between ESWL and ERCP is 12-36h   
   Changhai Hospital
      2022   -   NCT05270434   China;
Time interval between ESWL and ERCP is 12h   
   Changhai Hospital
      2022   -   NCT05270434   China;
Time interval between ESWL and ERCP is greater than 36h   
   Changhai Hospital
      2022   -   NCT05270434   China;
Triamcinolone   
   Indiana University
      2002   -   NCT00583271   United States;
   The Cleveland Clinic
      2008   Phase 3   NCT00658736   United States;
VIOKASE 16   
   Axcan Pharma
      2008   Phase 2   NCT00559052   Czech Republic;United States;
Viokase 16 (pancrelipase) + Nexium   
   University of Florida
      2009   Phase 1   NCT01142128   United States;
Viokase® 16   
   Forest Laboratories
      2007   Phase 3   NCT00559364   Canada;Germany;Poland;Slovakia;United States;
Vitamin D   
   Tampere University Hospital
      2016   -   NCT02965898   Finland;
Yarrowia lipolytica lipase   
   Laboratoires Mayoly Spindler
      2010   -   EUCTR2010-018900-10-FR   France;
ZENTASE   
   EURAND SPA
      2008   -   EUCTR2008-000061-37-IT   Italy;
Zenpep   
   Forest Laboratories
      2010   Phase 1   NCT01159119   United States;
dehydrated alcohol   
   Indiana University
      2002   -   NCT00583271   United States;