337. Homocystinuria Disease details / Clinical trials / Drug dev / DR info


Clinical trials : 16 Drugs : 19 - (DrugBank : 7) / Drug target genes : 2 - Drug target pathways : 23

Drugs and their primary sponsors and trial info
5-MTHF   
   Zambon Group S.p.A
      2007   -   EUCTR2006-000614-21-AT   Austria;Hungary;Italy;United Kingdom;
      2006   Phase 2   EUCTR2006-000614-21-SK   Austria;Hungary;Slovakia;United Kingdom;
      2006   Phase 2   EUCTR2006-000614-21-HU   Austria;Hungary;Slovakia;United Kingdom;
      2006   -   EUCTR2006-000614-21-GB   Austria;Hungary;Italy;United Kingdom;
ACN00177   
   Aeglea Biotherapeutics
      2021   Phase 1/Phase 2   NCT05154890   Australia;United Kingdom;
   Aeglea Biotherapeutics, Inc.
      2020   Phase 1   EUCTR2019-004791-19-GB   United Kingdom;
Acetaminophen   
   Hospital de Clinicas de Porto Alegre
      2022   Phase 1/Phase 2   NCT04015557   Brazil;
Betaine   
   Assistance Publique - Hôpitaux de Paris
      2015   Phase 2   NCT02404337   France;
Detoxifying agents for antineoplastic treatment   
   ZAMBON GROUP
      2006   -   EUCTR2006-000614-21-IT   Austria;Hungary;Italy;United Kingdom;
Epi-743   
   Bambino Gesù Hospital and Research Institute
      2013   Phase 2   NCT01793090   Italy;
IUPAC name: 2-[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylam ino]benzoyl]amino   
   Zambon Group S.p.A
      2007   -   EUCTR2006-000614-21-AT   Austria;Hungary;Italy;United Kingdom;
      2006   Phase 2   EUCTR2006-000614-21-SK   Austria;Hungary;Slovakia;United Kingdom;
      2006   Phase 2   EUCTR2006-000614-21-HU   Austria;Hungary;Slovakia;United Kingdom;
      2006   -   EUCTR2006-000614-21-GB   Austria;Hungary;Italy;United Kingdom;
N-acetylcysteine   
   Hospital de Clinicas de Porto Alegre
      2022   Phase 1/Phase 2   NCT04015557   Brazil;
   McGill University Health Center
      2007   Phase 2   NCT00483314   Canada;
PREFOLIC 15*30CPR GASTROR   
   ZAMBON GROUP
      2006   -   EUCTR2006-000614-21-IT   Austria;Hungary;Italy;United Kingdom;
Pegtibatinase   
   Orphan Technologies Ltd
      2019   Phase 1/Phase 2   NCT03406611   United States;
Prefolic   
   Zambon Group S.p.A
      2007   -   EUCTR2006-000614-21-AT   Austria;Hungary;Italy;United Kingdom;
      2006   Phase 2   EUCTR2006-000614-21-SK   Austria;Hungary;Slovakia;United Kingdom;
      2006   Phase 2   EUCTR2006-000614-21-HU   Austria;Hungary;Slovakia;United Kingdom;
      2006   -   EUCTR2006-000614-21-GB   Austria;Hungary;Italy;United Kingdom;
Taurine   
   University of Colorado, Denver
      2010   Phase 1/Phase 2   NCT01192828   United States;