337. Homocystinuria Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 16 / Drugs : 19 - (DrugBank : 7) / Drug target genes : 2 - Drug target pathways : 23
Drugs and their primary sponsors and trial info
5-MTHF
Zambon Group S.p.A
2007 - EUCTR2006-000614-21-AT Austria;Hungary;Italy;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-SK Austria;Hungary;Slovakia;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-HU Austria;Hungary;Slovakia;United Kingdom;
2006 - EUCTR2006-000614-21-GB Austria;Hungary;Italy;United Kingdom;
ACN00177
Aeglea Biotherapeutics
2021 Phase 1/Phase 2 NCT05154890 Australia;United Kingdom;
Aeglea Biotherapeutics, Inc.
2020 Phase 1 EUCTR2019-004791-19-GB United Kingdom;
Acetaminophen
Hospital de Clinicas de Porto Alegre
2022 Phase 1/Phase 2 NCT04015557 Brazil;
Betaine
Assistance Publique - Hôpitaux de Paris
2015 Phase 2 NCT02404337 France;
Detoxifying agents for antineoplastic treatment
ZAMBON GROUP
2006 - EUCTR2006-000614-21-IT Austria;Hungary;Italy;United Kingdom;
Epi-743
Bambino Gesù Hospital and Research Institute
2013 Phase 2 NCT01793090 Italy;
IUPAC name: 2-[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylam ino]benzoyl]amino
Zambon Group S.p.A
2007 - EUCTR2006-000614-21-AT Austria;Hungary;Italy;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-SK Austria;Hungary;Slovakia;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-HU Austria;Hungary;Slovakia;United Kingdom;
2006 - EUCTR2006-000614-21-GB Austria;Hungary;Italy;United Kingdom;
N-acetylcysteine
Hospital de Clinicas de Porto Alegre
2022 Phase 1/Phase 2 NCT04015557 Brazil;
McGill University Health Center
2007 Phase 2 NCT00483314 Canada;
PREFOLIC 15*30CPR GASTROR
ZAMBON GROUP
2006 - EUCTR2006-000614-21-IT Austria;Hungary;Italy;United Kingdom;
Pegtibatinase
Orphan Technologies Ltd
2019 Phase 1/Phase 2 NCT03406611 United States;
Prefolic
Zambon Group S.p.A
2007 - EUCTR2006-000614-21-AT Austria;Hungary;Italy;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-SK Austria;Hungary;Slovakia;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-HU Austria;Hungary;Slovakia;United Kingdom;
2006 - EUCTR2006-000614-21-GB Austria;Hungary;Italy;United Kingdom;
Taurine
University of Colorado, Denver
2010 Phase 1/Phase 2 NCT01192828 United States;
Zambon Group S.p.A
2007 - EUCTR2006-000614-21-AT Austria;Hungary;Italy;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-SK Austria;Hungary;Slovakia;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-HU Austria;Hungary;Slovakia;United Kingdom;
2006 - EUCTR2006-000614-21-GB Austria;Hungary;Italy;United Kingdom;
ACN00177
Aeglea Biotherapeutics
2021 Phase 1/Phase 2 NCT05154890 Australia;United Kingdom;
Aeglea Biotherapeutics, Inc.
2020 Phase 1 EUCTR2019-004791-19-GB United Kingdom;
Acetaminophen
Hospital de Clinicas de Porto Alegre
2022 Phase 1/Phase 2 NCT04015557 Brazil;
Betaine
Assistance Publique - Hôpitaux de Paris
2015 Phase 2 NCT02404337 France;
Detoxifying agents for antineoplastic treatment
ZAMBON GROUP
2006 - EUCTR2006-000614-21-IT Austria;Hungary;Italy;United Kingdom;
Epi-743
Bambino Gesù Hospital and Research Institute
2013 Phase 2 NCT01793090 Italy;
IUPAC name: 2-[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylam ino]benzoyl]amino
Zambon Group S.p.A
2007 - EUCTR2006-000614-21-AT Austria;Hungary;Italy;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-SK Austria;Hungary;Slovakia;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-HU Austria;Hungary;Slovakia;United Kingdom;
2006 - EUCTR2006-000614-21-GB Austria;Hungary;Italy;United Kingdom;
N-acetylcysteine
Hospital de Clinicas de Porto Alegre
2022 Phase 1/Phase 2 NCT04015557 Brazil;
McGill University Health Center
2007 Phase 2 NCT00483314 Canada;
PREFOLIC 15*30CPR GASTROR
ZAMBON GROUP
2006 - EUCTR2006-000614-21-IT Austria;Hungary;Italy;United Kingdom;
Pegtibatinase
Orphan Technologies Ltd
2019 Phase 1/Phase 2 NCT03406611 United States;
Prefolic
Zambon Group S.p.A
2007 - EUCTR2006-000614-21-AT Austria;Hungary;Italy;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-SK Austria;Hungary;Slovakia;United Kingdom;
2006 Phase 2 EUCTR2006-000614-21-HU Austria;Hungary;Slovakia;United Kingdom;
2006 - EUCTR2006-000614-21-GB Austria;Hungary;Italy;United Kingdom;
Taurine
University of Colorado, Denver
2010 Phase 1/Phase 2 NCT01192828 United States;