39. Toxic epidermal necrolysis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 13 / Drugs : 19 - (DrugBank : 8) / Drug target genes : 11 - Drug target pathways : 103
Drugs and their primary sponsors and trial info
Adipose derived stromal cells intravenously injected
Assistance Publique - Hôpitaux de Paris
2022 Phase 1/Phase 2 NCT04711200 -
Clobetasol ointment
University of California, Davis
2016 Phase 1/Phase 2 NCT02319616 United States;
Cyclosporine 5 mg/kg bid days 0-14
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Etanercept
Abe Riichirou
2021 Phase 2 JPRN-jRCTs031210325 Japan;
Etanercept 50 mg sc day 0 and day 3
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Harmonized supportive care
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Infliximab
Massachusetts Eye and Ear Infirmary
2010 Phase 1/Phase 2 NCT01256489 United States;
Intravenous immunoglobulin
Nihon Pharmaceutical Co., Ltd
2012 Phase 3 NCT01696500 Japan;
Isotretinoin
Massachusetts General Hospital
2016 - NCT02795143 United States;
Methylprednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
NaCl
University of Liege
2016 Phase 4 NCT02739295 Belgium;
Palifermin
Brett King
2010 Phase 1/Phase 2 NCT02037347 United States;
Prednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
Recombinant granulocyte - colony stimulating factor
University of Liege
2016 Phase 4 NCT02739295 Belgium;
Remicaide (infliximab)
Loyola University
2006 Phase 2 NCT00372723 United States;
Site specific standard of care comparison
Massachusetts General Hospital
2021 - NCT03585946 -
Topical infliximab
James Chodosh, MD, MPH
2014 Phase 1/Phase 2 NCT02126020 Canada;United States;
Assistance Publique - Hôpitaux de Paris
2022 Phase 1/Phase 2 NCT04711200 -
Clobetasol ointment
University of California, Davis
2016 Phase 1/Phase 2 NCT02319616 United States;
Cyclosporine 5 mg/kg bid days 0-14
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Etanercept
Abe Riichirou
2021 Phase 2 JPRN-jRCTs031210325 Japan;
Etanercept 50 mg sc day 0 and day 3
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Harmonized supportive care
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Infliximab
Massachusetts Eye and Ear Infirmary
2010 Phase 1/Phase 2 NCT01256489 United States;
Intravenous immunoglobulin
Nihon Pharmaceutical Co., Ltd
2012 Phase 3 NCT01696500 Japan;
Isotretinoin
Massachusetts General Hospital
2016 - NCT02795143 United States;
Methylprednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
NaCl
University of Liege
2016 Phase 4 NCT02739295 Belgium;
Palifermin
Brett King
2010 Phase 1/Phase 2 NCT02037347 United States;
Prednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
Recombinant granulocyte - colony stimulating factor
University of Liege
2016 Phase 4 NCT02739295 Belgium;
Remicaide (infliximab)
Loyola University
2006 Phase 2 NCT00372723 United States;
Site specific standard of care comparison
Massachusetts General Hospital
2021 - NCT03585946 -
Topical infliximab
James Chodosh, MD, MPH
2014 Phase 1/Phase 2 NCT02126020 Canada;United States;