42. Polyarteritis nodosa Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 15 / Drugs : 26 - (DrugBank : 16) / Drug target genes : 26 - Drug target pathways : 105
Drugs and their primary sponsors and trial info
Anti-thymocyte globulin
Fairview University Medical Center
2000 - NCT00006055 United States;
Autologous Peripheral Blood Stem Cell Transplantation
Fairview University Medical Center
2000 - NCT00006055 United States;
Azathioprine
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
University of Pennsylvania
2017 Phase 2 NCT02939573 Canada;Japan;United States;
CellCept (Mycophenolate Mofetil)
University College London
2016 Phase 3 EUCTR2013-004668-71-IT Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
2016 Phase 3 EUCTR2013-004668-71-ES Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
2014 Phase 3 EUCTR2013-004668-71-GB Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
- Phase 3 EUCTR2013-004668-71-PT Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
- Phase 3 EUCTR2013-004668-71-BE Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
Colchicine
University of Pennsylvania
2017 Phase 2 NCT02939573 Canada;Japan;United States;
Corticosteroid and azathioprine
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00647166 France;
Cyclophosphamide
Fairview University Medical Center
2000 - NCT00006055 United States;
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
University College London
2016 Phase 3 EUCTR2013-004668-71-IT Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
2014 Phase 3 EUCTR2013-004668-71-GB Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
University of Parma
2008 Phase 2 NCT00751517 Italy;
Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Cyclosporine
Fairview University Medical Center
2000 - NCT00006055 United States;
Dapsone
University of Pennsylvania
2017 Phase 2 NCT02939573 Canada;Japan;United States;
Filgrastim
Fairview University Medical Center
2000 - NCT00006055 United States;
Infliximab
Cambridge University Hospitals NHS Foundation Trust
2020 Phase 2 EUCTR2019-003964-30-GB United Kingdom;
Lamivudine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
1995 Phase 2 NCT00001457 United States;
Methotrexate
University of Parma
2008 Phase 2 NCT00751517 Italy;
Methylprednisolone
Fairview University Medical Center
2000 - NCT00006055 United States;
Mycophenolate mofetil,methotrexate
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Naltrexone Hydrochloride
University of Pennsylvania
2019 Phase 2 NCT03482479 United States;
Prednisone
Fairview University Medical Center
2000 - NCT00006055 United States;
Prednisone, methylprednisolone,cyclophosphamides
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Rituximab
Cambridge University Hospitals NHS Foundation Trust
2020 Phase 2 EUCTR2019-003964-30-GB United Kingdom;
Tocilizumab
Cambridge University Hospitals NHS Foundation Trust
2020 Phase 2 EUCTR2019-003964-30-GB United Kingdom;
Fairview University Medical Center
2000 - NCT00006055 United States;
Autologous Peripheral Blood Stem Cell Transplantation
Fairview University Medical Center
2000 - NCT00006055 United States;
Azathioprine
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
University of Pennsylvania
2017 Phase 2 NCT02939573 Canada;Japan;United States;
CellCept (Mycophenolate Mofetil)
University College London
2016 Phase 3 EUCTR2013-004668-71-IT Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
2016 Phase 3 EUCTR2013-004668-71-ES Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
2014 Phase 3 EUCTR2013-004668-71-GB Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
- Phase 3 EUCTR2013-004668-71-PT Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
- Phase 3 EUCTR2013-004668-71-BE Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
Colchicine
University of Pennsylvania
2017 Phase 2 NCT02939573 Canada;Japan;United States;
Corticosteroid and azathioprine
Assistance Publique - Hôpitaux de Paris
2008 Phase 3 NCT00647166 France;
Cyclophosphamide
Fairview University Medical Center
2000 - NCT00006055 United States;
Hospices Civils de Lyon
1996 Phase 4 NCT00400075 Switzerland;
University College London
2016 Phase 3 EUCTR2013-004668-71-IT Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
2014 Phase 3 EUCTR2013-004668-71-GB Belgium;Croatia;Czech Republic;Germany;Greece;Italy;Netherlands;Poland;Portugal;Slovenia;Spain;Sweden;Turkey;United Kingdom;
University of Parma
2008 Phase 2 NCT00751517 Italy;
Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Cyclosporine
Fairview University Medical Center
2000 - NCT00006055 United States;
Dapsone
University of Pennsylvania
2017 Phase 2 NCT02939573 Canada;Japan;United States;
Filgrastim
Fairview University Medical Center
2000 - NCT00006055 United States;
Infliximab
Cambridge University Hospitals NHS Foundation Trust
2020 Phase 2 EUCTR2019-003964-30-GB United Kingdom;
Lamivudine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
1995 Phase 2 NCT00001457 United States;
Methotrexate
University of Parma
2008 Phase 2 NCT00751517 Italy;
Methylprednisolone
Fairview University Medical Center
2000 - NCT00006055 United States;
Mycophenolate mofetil,methotrexate
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Naltrexone Hydrochloride
University of Pennsylvania
2019 Phase 2 NCT03482479 United States;
Prednisone
Fairview University Medical Center
2000 - NCT00006055 United States;
Prednisone, methylprednisolone,cyclophosphamides
Assistance Publique - Hôpitaux de Paris
2005 Phase 4 NCT00307671 France;
Rituximab
Cambridge University Hospitals NHS Foundation Trust
2020 Phase 2 EUCTR2019-003964-30-GB United Kingdom;
Tocilizumab
Cambridge University Hospitals NHS Foundation Trust
2020 Phase 2 EUCTR2019-003964-30-GB United Kingdom;