DR info

Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228

Malignant rheumatoid arthritis and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
46	Malignant rheumatoid arthritis
13	Multiple sclerosis/Neuromyelitis optica
96	Crohn disease
97	Ulcerative colitis
6	Parkinson disease
49	Systemic lupus erythematosus
2	Amyotrophic lateral sclerosis
70	Spinal stenosis
51	Scleroderma
8	Huntington disease
65	Primary immunodeficiency
84	Sarcoidosis
107	Juvenile idiopathic arthritis
85	Idiopathic interstitial pneumonia
271	Ankylosing spondylitis
36	Epidermolysis bullosa
21	Mitochondrial disease
34	Neurofibromatosis
53	Sjogren syndrome
56	Behcet disease
113	Muscular dystrophy
299	Cystic fibrosis
50	Dermatomyositis
28	Systemic amyloidosis
298	Hereditary pancreatitis
11	Myasthenia gravis
158	Tuberous sclerosis
93	Primary biliary cholangitis
226	Interstitial cystitis with Hunners ulcer
41	Giant cell arteritis
206	Fragile X syndrome
22	Moyamoya disease
17	Multiple system atrophy
60	Aplastic anemia
162	Pemphigoid
42	Polyarteritis nodosa
40	Takayasu arteritis
78	Hypopituitarism
86	Pulmonary arterial hypertension
5	Progressive supranuclear palsy
66	IgA nephropathy
231	Alpha-1-antitrypsin deficiency
285	Fanconi anemia
205	Fragile X syndrome related disease
58	Hypertrophic cardiomyopathy
98	Eosinophilic gastrointestinal disease
145	West syndrome
222	Primary nephrotic syndrome
18	Spinocerebellar degeneration
63	Idiopathic thrombocytopenic purpura
95	Autoimmune hepatitis
19	Lysosomal storage disease
156	Rett syndrome
3	Spinal muscular atrophy
210	Single Ventricle
193	Prader-Willi syndrome
228	Bronchiolitis obliterans
164	Oculocutaneous albinism
283	Acquired pure red cell aplasia
152	PCDH19 related syndrome
265	Lipodystrophy
144	Lennox-Gastaut syndrome
296	Biliary atresia
35	Pemphigus
224	Purpura nephritis
256	Muscle glycogenosis
75	Cushing disease
140	Dorabe syndrome
45	Eosinophilic granulomatosis with Polyangiitis
44	Wegener granulomatosis
266	Familial mediterranean fever
26	HTLV-1-associated myelopathy
331	Idiopathic multicentric castleman disease
284	Diamond-Blackfan anemia
201	Angelman syndrome
61	Autoimmune hemolytic anemia
127	Frontotemporal lobar degeneration
38	Stevens-Johnson syndrome
300	IgG4-related disease
269	Pyogenic arthritis
55	Relapsing polychondritis
272	Fibrodysplasia ossificans progressiva
215	Tetralogy of Fallot
20	Adrenoleukodystrophy
43	Microscopic polyangiitis
234	Peroxisomal disease (except Adrenoleukodystrophy)
62	Paroxysmal nocturnal hemoglobinuria
288	Autoimmune acquired coagulation factor deficiency
160	Congenital ichthyosis
155	Acquired aphasia with convulsive disorder
326	Osteopetrosis
57	Idiopathic dilated cardiomyopathy
169	Menkes disease
170	Occipital horn syndrome
227	Osler disease
280	Huge arteriovenous malformation with cervicofacial or limb lesion
286	Hereditary sideroblastic anemia
94	Primary sclerosing cholangitis
64	Thrombotic thrombocytopenic purpura
236	Pseudohypoparathyroidism
10	Charcot-Marie-Tooth disease
274	Osteogenesis Imperfecta
168	Ehlers-Danlos syndrome
25	Progressive multifocal leukoencephalopathy
1	Spinal and bulbar muscular atrophy
37	Generalised pustular psoriasis
118	Myelomeningocele
270	Chronic recurrent multifocal osteomyelitis
151	Rasmussen encephalitis
83	Addison disease
76	Pituitary gonadotropin secretion hyperthyroidism
39	Toxic epidermal necrolysis
15	Inclusion body myositis
67	Polycystic kidney disease
157	Sturge-Weber syndrome
278	Huge lymphatic malformation with cervicofacial lesion
302	Leber hereditary optic neuropathy
294	Congenital diaphragmatic hernia
4	Primary lateral sclerosis
90	Retinitis pigmentosa
106	Cryopyrin-associated periodic syndrome
71	Idiopathic osteonecrosis of the femoral head
246	Methylmalonic acidemia
88	Chronic thromboembolic pulmonary hypertension
16	Crow-Fukase syndrome
81	Congenital adrenal hyperplasia
310	Congenital anomalies syndrome
229	Autoimmune pulmonary alveolar proteinosis
323	Aromatic L-amino acid decarboxylase deficiency
218	Alport syndrome
89	Lymphangioleiomyomatosis
167	Marfan syndrome
225	Congenital nephrogenic diabetes insipidus
87	Pulmonary veno-occlusive disease
251	Urea cycle disorder
91	Budd-Chiari syndrome
235	Hypoparathyroidism
202	Smith-Magenis syndrome
212	Tricuspid atresia
254	Porphyria
77	Growth hormone secreting pituitary adenoma
268	Nakajo-Nishimura syndrome
325	Hereditary autoinflammatory syndrome
337	Homocystinuria
195	Noonan syndrome
263	Cerebrotendinous xanthomatosis
257	Hepatic glycogenosis
282	Congenital dyserythropoietic anemia
120	Hereditary dystonia
203	22q11.2 deletion syndrome
179	Williams syndrome
211	Hypoplastic left heart syndrome
74	Prolactin secreting pituitary adenoma
149	Hemiconvulsion hemiplegia epilepsy syndrome
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
47	Buerger disease
114	Non-dystrophic myotonia syndrome
14	Chronic inflammatory demyelinating polyneuropathy
187	Kabuki syndrome
171	Wilson disease
172	Hypophosphatasia
79	Homozygous familial hypercholesterolemia
301	Macular dystrophy
333	Hutchinson-Gilford syndrome
238	Vitamin D-resistant rickets
137	Focal cortical dysplasia
192	Cockayne syndrome
277	Lymphangiomatosis
281	Klippel-Trenaunay-Weber syndrome
111	Congenital myopathy
108	TNF receptor-associated periodic syndrome
267	Hyper-IgD syndrome
317	Trifunctional protein deficiency
54	Adult still disease
191	Werner syndrome
68	Ossification of the ligamentum flavum
52	Mixed connective tissue disease
220	Rapidly progressive glomerulonephritis
30	Distal myopathy