74. Prolactin secreting pituitary adenoma Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 19 / Drugs : 28 - (DrugBank : 10) / Drug target genes : 14 - Drug target pathways : 65
Drugs and their primary sponsors and trial info
Bromocriptine
First affiliated hospital of Sun Yat-sen University
2012 - ChiCTR-ONC-12002194 -
Cabergoline
Federico II University
2007 - NCT00460616 Italy;
Seoul National University Hospital
2018 - NCT03457389 Korea, Republic of;
Universidade Federal do Rio de Janeiro
2010 Phase 2/Phase 3 NCT01620138 Brazil;
Clomiphene citrate
Federal University of São Paulo
2004 Phase 2 NCT00697814 Brazil;
Curcumin
Mashhad University of Medical Sciences
2011 Phase 1 NCT01344291 Iran, Islamic Republic of;
Dexamethasone
National Cancer Institute (NCI)
2010 Phase 1 NCT01088763 Canada;United States;
Dopamine Agonists
Leiden University Medical Center
2019 Phase 4 NCT04107480 Netherlands;
Dopamine agonist treatment
First Affiliated Hospital, Sun Yat-Sen University
2016 - NCT03353025 China;
Drug treatment
Zhebao Wu
2018 - NCT03717454 -
Endoscopic trans-sphenoidal adenoma resection
Leiden University Medical Center
2019 Phase 4 NCT04107480 Netherlands;
Gamma-secretase/Notch signalling pathway inhibitor RO4929097
National Cancer Institute (NCI)
2010 Phase 1 NCT01088763 Canada;United States;
Genotropin Miniqu
Amar Agha, Beaumont Hospital
2009 - EUCTR2009-010918-30-IE Ireland;
Genotropin Miniquick
Amar Agha, Beaumont Hospital
2009 - EUCTR2009-010918-30-IE Ireland;
HCQ/CQ and CAB combined treatment
Zhebao Wu
2018 - NCT03400865 China;
Lapatinib
Cedars-Sinai Medical Center
2009 Phase 2 NCT00939523 United States;
Pasireotide
Novartis Pharma Services AG
2009 Phase 2 EUCTR2008-007348-32-FR France;Germany;Italy;Spain;
2009 Phase 2 EUCTR2008-007348-32-DE Argentina;Australia;Brazil;Canada;Colombia;France;Germany;Italy;Mexico;Russian Federation;South Africa;Spain;United States;
Universidade Federal do Rio de Janeiro
2010 Phase 2/Phase 3 NCT01620138 Brazil;
Universitätsklinikum Essen - Zentrum für Innere Medizin - Klinik für Endokrinologie
2008 - EUCTR2006-007036-95-DE Germany;
Ropinirole
Columbia University
2016 Phase 1/Phase 2 NCT03038308 United States;
SOM230
NOVARTIS FARMA
2009 - EUCTR2008-007348-32-IT France;Germany;Italy;Spain;
Novartis Pharma Services AG
2009 Phase 2 EUCTR2008-007348-32-FR France;Germany;Italy;Spain;
2009 Phase 2 EUCTR2008-007348-32-DE Argentina;Australia;Brazil;Canada;Colombia;France;Germany;Italy;Mexico;Russian Federation;South Africa;Spain;United States;
Universitätsklinikum Essen - Zentrum für Innere Medizin - Klinik für Endokrinologie
2008 - EUCTR2006-007036-95-DE Germany;
Transsphenoidal surgery treatment
First Affiliated Hospital, Sun Yat-Sen University
2016 - NCT03353025 China;
First affiliated hospital of Sun Yat-sen University
2012 - ChiCTR-ONC-12002194 -
Cabergoline
Federico II University
2007 - NCT00460616 Italy;
Seoul National University Hospital
2018 - NCT03457389 Korea, Republic of;
Universidade Federal do Rio de Janeiro
2010 Phase 2/Phase 3 NCT01620138 Brazil;
Clomiphene citrate
Federal University of São Paulo
2004 Phase 2 NCT00697814 Brazil;
Curcumin
Mashhad University of Medical Sciences
2011 Phase 1 NCT01344291 Iran, Islamic Republic of;
Dexamethasone
National Cancer Institute (NCI)
2010 Phase 1 NCT01088763 Canada;United States;
Dopamine Agonists
Leiden University Medical Center
2019 Phase 4 NCT04107480 Netherlands;
Dopamine agonist treatment
First Affiliated Hospital, Sun Yat-Sen University
2016 - NCT03353025 China;
Drug treatment
Zhebao Wu
2018 - NCT03717454 -
Endoscopic trans-sphenoidal adenoma resection
Leiden University Medical Center
2019 Phase 4 NCT04107480 Netherlands;
Gamma-secretase/Notch signalling pathway inhibitor RO4929097
National Cancer Institute (NCI)
2010 Phase 1 NCT01088763 Canada;United States;
Genotropin Miniqu
Amar Agha, Beaumont Hospital
2009 - EUCTR2009-010918-30-IE Ireland;
Genotropin Miniquick
Amar Agha, Beaumont Hospital
2009 - EUCTR2009-010918-30-IE Ireland;
HCQ/CQ and CAB combined treatment
Zhebao Wu
2018 - NCT03400865 China;
Lapatinib
Cedars-Sinai Medical Center
2009 Phase 2 NCT00939523 United States;
Pasireotide
Novartis Pharma Services AG
2009 Phase 2 EUCTR2008-007348-32-FR France;Germany;Italy;Spain;
2009 Phase 2 EUCTR2008-007348-32-DE Argentina;Australia;Brazil;Canada;Colombia;France;Germany;Italy;Mexico;Russian Federation;South Africa;Spain;United States;
Universidade Federal do Rio de Janeiro
2010 Phase 2/Phase 3 NCT01620138 Brazil;
Universitätsklinikum Essen - Zentrum für Innere Medizin - Klinik für Endokrinologie
2008 - EUCTR2006-007036-95-DE Germany;
Ropinirole
Columbia University
2016 Phase 1/Phase 2 NCT03038308 United States;
SOM230
NOVARTIS FARMA
2009 - EUCTR2008-007348-32-IT France;Germany;Italy;Spain;
Novartis Pharma Services AG
2009 Phase 2 EUCTR2008-007348-32-FR France;Germany;Italy;Spain;
2009 Phase 2 EUCTR2008-007348-32-DE Argentina;Australia;Brazil;Canada;Colombia;France;Germany;Italy;Mexico;Russian Federation;South Africa;Spain;United States;
Universitätsklinikum Essen - Zentrum für Innere Medizin - Klinik für Endokrinologie
2008 - EUCTR2006-007036-95-DE Germany;
Transsphenoidal surgery treatment
First Affiliated Hospital, Sun Yat-Sen University
2016 - NCT03353025 China;