222. 一次性ネフローゼ症候群 ［臨床試験数：234，薬物数：241（DrugBank：78），標的遺伝子数：59，標的パスウェイ数：185］
Searched query = "Primary nephrotic syndrome", "Minimal change nephrotic syndrome", "MCNS", "Membranous nephropathy", "Focal segmental glomerulosclerosis", "FSGS", "Membranoproliferative glomerulonephritis", "MPGN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
|1||NCT04278729||December 2020||18/2/2020||A Prospective Multi-dose Study of Apixaban in Subjects With Nephrotic Syndrome||A Prospective Multi-dose Study of Apixaban in Subjects With Nephrotic Syndrome||Nephrotic Syndrome;Membranous Nephropathy||Drug: Apixaban 5 MG||University of North Carolina, Chapel Hill||American College of Clinical Pharmacy||Not yet recruiting||18 Years||79 Years||All||30||Phase 1||United States|
|2||EUCTR2019-001212-29-DK||13/08/2020||09/06/2020||Causes and prevention of thrombosis developed due to the kidney disease nephrotic syndrome||Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome||Nephrotic syndrome is defined as severe proteinuria (> 0.5 g / day), edema and hypoalbuminemia. It is conditioned by a defect in the kidney's glomerular filtration barrier, resulting in the loss of a large number of plasma proteins including coagulation factors and consequently a increased risk of thromboembolic complications. The most frequent cause of nephrotic syndrome is the renal disease membranous nephropathy, which is associated with the greatest risk of thromboembolic complications. |
MedDRA version: 21.1Level: LLTClassification code 10029167Term: Nephrotic syndrome with lesion of membranous glomerulonephritisSystem Organ Class: 100000004857
MedDRA version: 20.0Level: LLTClassification code 10029165Term: Nephrotic syndrome in diseases classified elsewhereSystem Organ Class: 100000004857;Therapeutic area: Not possible to specify
|Trade Name: Fragmin|
INN or Proposed INN: Dalteparin
Other descriptive name: Dalteparin
Trade Name: Eliquis
INN or Proposed INN: Apixaban
Other descriptive name: Apixaban
|Aarhus University Hospital, Henrik Birn||NULL||Authorised-recruitment may be ongoing or finished||Female: yes|
|50||Phase 1;Phase 2||Denmark|