Edoxaban

( DrugBank: Edoxaban / KEGG DRUG: Edoxaban )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
46	悪性関節リウマチ	2

告示番号	疾患名（ページ内リンク）	臨床試験数
88	慢性血栓塞栓性肺高血圧症	3

46. 悪性関節リウマチ

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000026819	2016/11/21	01/04/2017	A randomized controlled trial of low-dose Enoxaparin versus low-dose Edoxavan for prevention of veno ...	A randomized controlled trial of low-dose Enoxaparin versus low-dose Edoxavan for prevention of veno ...	osteoarthritis of the hip, osteonecrosis of the femoral head, femoral neck fracture, rheumatoid arth ...	Dose: Edoxabangroup; Edoxaban15mg per day Enoxaparin gropu; Enoxaparin 2000 IU per day Intervention per ...	Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry, and Ph ...	NULL	Complete: follow-up complete	20years-old	Not applicable	Male and Female	80	Not selected	Japan
2	JPRN-UMIN000018101	2012/10/01	26/06/2015	Venous thromboembolism after total knee arthroplasty and high tibial osteotomy with / without edxaba ...	Venous thromboembolism after total knee arthroplasty and high tibial osteotomy with / without edxaba ...	Osteoarthritis, rheumatoid arthritis, osteonecrosis	To determine whether postoperative VTE is present and to evaluate the efficacy and safety of edoxaba ...	Yokohama City University School of Medicine	NULL	Complete: follow-up complete	Not applicable	Not applicable	Male and Female	100	Not selected	Japan

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88. 慢性血栓塞栓性肺高血圧症

臨床試験数 : 157 / 薬物数 : 107 - (DrugBank : 22) / 標的遺伝子数 : 14 - 標的パスウェイ数 : 54

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCT2071200098	09/04/2021	08/02/2021	Phase III Investigator-Initiated Trial to Investigate Safety and Efficacy of Edoxabanin Patients wit ...	An Investigator-initiated, multicenter, phase 3, randomized, single-blind, double-dummy, parallel-gr ...	Chronic Thromboembolic Pulmonary Hypertension CTEPH, DOAC, warfarin	Oral administeration of (1) or (2) (1) Edoxabangroup - Edoxaban30 mg/60 mg tablet according to body w ...	Abe Kohtaro	NULL	Not Recruiting	>= 20age old	<= 85age old	Both	74	Phase 3	Japan
2	NCT04730037 (ClinicalTrials.gov)	April 9, 2021	25/1/2021	Clinical Trial to Investigate Safety and Efficacy of Edoxaban in Patients With CTEPH (KABUKI)	An Investigator-initiated, Multicenter, Phase 3, Randomized, Single-blind, Double-dummy, Parallel-gr ...	CTEPH	Drug: Edoxaban;Drug: Warfarin Potassium;Drug: Warfarin Potassium placebo;Drug: Edoxaban placebo	Kyushu University	Daiichi Sankyo Co., Ltd.	Active, not recruiting	20 Years	85 Years	All	74	Phase 3	Japan
3	JPRN-UMIN000018520	2016/01/01	01/01/2016	Clinical efficacy and safety of edoxabanfor treatment of chronic thromboembolic pulmonary hypertensi ...	Clinical efficacy and safety of edoxabanfor treatment of chronic thromboembolic pulmonary hypertensi ...	CTEPH (chronic thromboembolic pulmonary hypertension)	Initiation of once-daily Edoxaban(60mg) during 6 months after 2 days discontinuation of warfarin	Division of Cardiovascular Medicine, Department of Internal Medicine Kobe University Graduate School ...	NULL	Complete: follow-up complete	20years-old	Not applicable	Male and Female	60	Phase 4	Japan

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