DDrare diagram
Disease Drug Target Gene/Pathway
[ Japanese / English ]

 Data ver. Mar2021 - Update: Mar 8, 2022 curr ver.

 Disease                            Sitemap

 Drug                                 Sitemap

 Target Gene/Pathway     Sitemap



    DDrare (Database of Drug Development for Rare Diseases) is a database that provides information on drugs in clinical trials, and drug target genes and pathways, related to the intractable diseases (mostly rare diseases) designated by the Ministry of Health, Labour and Welfare (MHLW), Japan.
    A list of disease names in English, including synonyms and subclass names, was originally created for the diseases (333 diseases on Mar 2021). Using the list as a query, clinical trials with drug information (DrugBank) was extracted from four major clinical trial registries: JPRN (Japan), ClinicalTrials.gov (US), EU-CTR (Europe), and ChiCTR (China), through WHO-ICTRP website.
    Information of drug target genes and pathways (KEGG) is assigned to the extracted drugs. DDrare enables cross-reference of disease, drug, and target gene/pathway information, to be utilized for drug discovery, especially for drug repositioning.



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