Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Anti-thymocyte globulin	-	-	-	-	18件: 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285 💬
2	Azathioprine	Azathioprine	2件: D00238, D03033 💬	-	-	20件:  6 , 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 94, 95, 96, 97, 162 💬
3	Benralizumab	Benralizumab	1件: D09874 💬	1件: IL5RA 💬	4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer	4件: 44, 45, 98, 162 💬
4	Corticosteroid	-	-	-	-	10件: 13, 42, 43, 44, 45, 66, 84, 96, 97, 222 💬
5	Corticosteroid and azathioprine	Azathioprine	2件: D00238, D03033 💬	-	-	4件: 42, 43, 44, 45 💬
6	Cyclophosphamide	Cyclophosphamide	2件: D00287, D07760 💬	-	-	44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
7	Cyclophosphamide, azathioprine,prednisone,methylprednisolone	Azathioprine	11件: D00238, D00287, D00407, D00473, D00751, D00979, D03033, D05000, D05001, D05002, D07760 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	3件: 42, 43, 45 💬
8	Cyclosporine	Cyclosporine	1件: D00184 💬	5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬	32件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway	35件: 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 63, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 💬
9	Filgrastim	Filgrastim	1件: D03235 💬	1件: CSF3R 💬	5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer	27件:  2 ,  6 , 13, 25, 26, 28, 34, 35, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
10	Freeze-dried sulfonated human normal immunoglobulin (ggs)	Human immunoglobulin G	-	-	-	3件: 14, 43, 45 💬
11	Hpc cell infusion	-	-	-	-	1件: 45 💬
12	Human normal immunoglobulin	Human immunoglobulin G	-	-	-	9件: 11, 13, 14, 43, 45, 50, 51, 63, 65 💬
13	Hydroxychloroquine	Hydroxychloroquine	1件: D08050 💬	-	-	23件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 66, 84, 89, 90, 96, 218, 222, 234, 254, 271, 298, 299 💬
14	Infliximab	Infliximab	1件: D02598 💬	1件: TNF 💬	65件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway	24件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 162, 164, 269, 271 💬
15	L04ac06	-	-	-	-	2件: 44, 45 💬
16	Medi-563	-	-	-	-	3件: 44, 45, 98 💬
17	Mepolizumab	Mepolizumab	1件: D04923 💬	1件: IL5 💬	13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation	4件: 44, 45, 98, 162 💬
18	Mesna	-	-	-	-	11件: 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬
19	Methotrexate	Methotrexate	2件: D00142, D02115 💬	2件: DHFR, DHFR2 💬	5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬
20	Methylprednisolone	Methylprednisolone	6件: D00407, D00751, D00979, D05000, D05001, D05002 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	44件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
21	Mycophenolate	Mycophenolic acid	1件: D05096 💬	2件: IMPDH1, IMPDH2 💬	3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
22	Mycophenolate mofetil	Mycophenolate mofetil	4件: D00752, D05094, D05095, D05096 💬	2件: IMPDH1, IMPDH2 💬	3件: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism	32件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
23	Mycophenolate mofetil,methotrexate	Methotrexate	6件: D00142, D00752, D02115, D05094, D05095, D05096 💬	4件: DHFR, DHFR2, IMPDH1, IMPDH2 💬	7件: Antifolate resistance, Biosynthesis of cofactors, Drug metabolism - other enzymes, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Purine metabolism	3件: 42, 43, 45 💬
24	Naltrexone	Naltrexone	2件: D02095, D05113 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	12件:  6 , 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
25	Naltrexone hydrochloride	Naltrexone	2件: D02095, D05113 💬	3件: OPRD1, OPRK1, OPRM1 💬	5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway	8件: 10, 40, 41, 42, 43, 44, 45, 96 💬
26	Nucala	-	-	-	-	2件: 44, 45 💬
27	Nucala 100 mg powder for solution for injection	-	-	-	-	2件: 44, 45 💬
28	Placebo (physiological saline)	-	-	-	-	2件: 43, 45 💬
29	Plaquenil - hydroxychloroquine 200mg film coated tablets	Hydroxychloroquine	1件: D08050 💬	-	-	3件: 43, 44, 45 💬
30	Prednisolone	Prednisolone	8件: D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
31	Prednisone	Prednisone	1件: D00473 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	47件:  2 ,  6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬
32	Prednisone, methylprednisolone,cyclophosphamides	Methylprednisolone	7件: D00407, D00473, D00751, D00979, D05000, D05001, D05002 💬	1件: NR3C1 💬	1件: Neuroactive ligand-receptor interaction	3件: 42, 43, 45 💬
33	Procedure: autologous peripheral blood stem cell transplantation	-	-	-	-	8件: 28, 40, 41, 42, 45, 46, 49, 283 💬
34	Rituximab	Rituximab	1件: D02994 💬	1件: MS4A1 💬	1件: Hematopoietic cell lineage	47件: 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
35	Sb-240563	-	-	-	-	3件: 44, 45, 98 💬
36	Sb-240563 (mepolizumab)	Mepolizumab	1件: D04923 💬	1件: IL5 💬	13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation	2件: 44, 45 💬

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