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29 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Bupropion  Bupropion  [3] D00817, D07591, D07938 💬  [2] SLC6A2, SLC6A3 💬  [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle  [5]  8 , 18, 21, 96, 171 💬 
 2  Caffeine  Caffeine  [2] D00528, D01453 💬  [11] ADORA1, ADORA2A, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬  [22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬 
 3  Coenzymeq10  -  -  -  -  [1] 21 💬 
 4  Cysteamine  Cysteamine  [2] D03634, D03635 💬  -  -  [4]  8 , 19, 21, 299 💬 
 5  Cysteamine bitartrate  Cysteamine  [2] D03634, D03635 💬  -  -  [4]  8 , 19, 21, 299 💬 
 6  Dexmedetomidine  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [12]  2 ,  4 ,  6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬 
 7  Dextromethorphan  Dextromethorphan  [3] D00848, D03742, D03744 💬  [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬  [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 
 8  Elamipretide  Elamipretide  [1] D10925 💬  -  -  [2] 21, 324 💬 
 9  Elamipretide (high dose)  Elamipretide  [1] D10925 💬  -  -  [1] 21 💬 
 10  Elamipretide (intermediate dose)  Elamipretide  [1] D10925 💬  -  -  [1] 21 💬 
 11  Elamipretide (low dose)  Elamipretide  [1] D10925 💬  -  -  [1] 21 💬 
 12  Epi-743  -  -  -  -  [2] 21, 156 💬 
 13  Flurbiprofen  Flurbiprofen  [3] D00330, D01475, D02290 💬  [2] PTGS1, PTGS2 💬  [23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [3] 13, 21, 46 💬 
 14  Fluzone  -  -  -  -  [2] 21, 49 💬 
 15  Fluzone®  -  -  -  -  [1] 21 💬 
 16  Kh176  -  -  -  -  [1] 21 💬 
 17  Kl1333  -  -  -  -  [1] 21 💬 
 18  Low residue diet intervention  -  -  -  -  [1] 21 💬 
 19  Midazolam  Midazolam  [3] D00550, D00696, D05028 💬  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬  [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [11]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 231, 298 💬 
 20  Midazolam injection  Midazolam  [3] D00550, D00696, D05028 💬  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬  [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [1] 21 💬 
 21  Omeprazole  Omeprazole  [4] D00455, D01207, D05259, D05261 💬  [2] ATP4A, ATP4B 💬  [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation  [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬 
 22  Propofol  Propofol  [1] D00549 💬  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬  [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction  [8]  6 , 21, 22, 34, 46, 84, 98, 296 💬 
 23  Repaglinide  Repaglinide  [1] D00594 💬  [2] ABCC8, KCNJ11 💬  [4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus  [3]  6 , 21, 299 💬 
 24  Rg2133 (2',3',5'-tri-o-acetyluridine)  Uridine triacetate  [1] D09985 💬  -  -  [1] 21 💬 
 25  Sevoflurane  Sevoflurane  [1] D00547 💬  -  -  [6]  6 , 21, 22, 34, 98, 296 💬 
 26  Sonlicromanol  Sonlicromanol  -  -  -  [1] 21 💬 
 27  Spp-004  -  -  -  -  [1] 21 💬 
 28  Tri-o-acetyluridine  Uridine triacetate  [1] D09985 💬  -  -  [1] 21 💬 
 29  Vatiquinone  Vatiquinone  [1] D10407 💬  -  -  [2] 18, 21 💬 

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