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e.g. Sirolimus, Adalimumab

ABCDEFGH I JKLMNOPQRSTUVWXYZother

72 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Acyclovir [1] Acyclovir;  [1] D00222 💬  -  -  [5] 13, 28, 46, 53, 60 💬
 2  Albendazole [2] Albendazole; Albendazole (eskazole);  [1] D00134 💬  -  -  [11]  5 ,  6 ,  7 , 28, 51, 67, 86, 96, 97, 114, 127 💬
 3  Amifostine [2] Amifostine; Amifostine trihydrate;  [1] D00226 💬  -  -  [1] 28 💬
 4  Amiodarone [3] Amiodarone; Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias); Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus egcg;  [2] D00636
D02910 💬		 [16] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCND3, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 [31] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway  [2] 28, 127 💬
 5  Anakinra [8] Anakinra; Anakinra (kineret®); Anakinra (r-methuil-1ra); Anakinra / kineret; Anakinra and peg stnf-r1; Kineret® (anakinra); Kineret® or anakinra; Response to anakinra associated with methotrexate;  [1] D02934 💬 [2] IL1R1, IL1R2 💬 [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer  [19]  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
 6  Aprotinin [1] Aprotinin;  [1] D02971 💬  -  -  [1] 28 💬
 7  Belantamab mafodotin [1] Belantamab mafodotin;  [1] D11595 💬  -  -  [1] 28 💬
 8  Bendamustine [3] Bendamustine; Bendamustine hydrochloride; Bendamustine, rituximab;  [2] D07085
D07501 💬		  -  -  [2] 28, 61 💬
 9  Betamethasone [6] Betamethasone; Betamethasone acibutate; Betamethasone sodium phosphate/betamethasone acetate (celestone® soluspan®), 30 mg im once a day for four days; Intra-articular compound betamethasone; Intraarticular betamethasone; Phosphate and betamethasone acetate, 2 ml.;  [7] D00244
D00972
D01357
D01402
D01637
D02032
D02286 💬		 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [6]  2 , 28, 46, 90, 96, 235 💬
 10  Bortezomib [8] Bortezomib; Bortezomib (velcade®); Bortezomib/dexamethasone; Bortezomib/dexamethasone (bd), followed by autologous stc & maintenance bortezomib/dexamethasone; Combination of a single dose anti-cd20 antibody and bortezomib; Cyclophosphamide, bortezomib, and dexamethasone (cybord); Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab;  [1] D03150 💬 [1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia  [15] 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬
 11  Busulfan [15] Busulfan; Busulfan iv; Busulfan test dose; Busulfan, cyclophosphamide, antithymocyte globulin; Busulfan, cyclophosphamide, atg; Busulfan, cyclophosphamide, atg, gcsf; Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Busulfan, fludarabine and atg; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Busulfan, fludarabine, atg, tli; Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf; Busulfano; Campath, busulfan, clofarabine; Fludarabine, busulfan, thymoglobulin; Fludarabine/busulfan;  [1] D00248 💬  -  -  [13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
 12  Butylene glycol - [1] D10695 💬  -  -  [2] 28, 46 💬
 13  Carboplatin [1] Carboplatin;  [1] D01363 💬  -  -  [4] 28, 34, 60, 85 💬
 14  Carfilzomib [1] Carfilzomib;  [1] D08880 💬 [1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia  [1] 28 💬
 15  Carmustine [2] Carmustine; Carmustine, etoposide, cytarabine, and melphalan (beam);  [1] D00254 💬  -  -  [5] 11, 13, 14, 28, 60 💬
 16  Cholecalciferol [11] 5000 iu of cholecalciferol; Calcium and cholecalciferol; Cholecalciferol; Cholecalciferol (vitamin d3); Cholecalciferol (vitamind3); Cholecalciferol 10,000 iu; Cholecalciferol 400 iu; Cholecalciferol and c. xanthorrhiza; Cholecalciferol concentrate; Cholecalciferol concentrate (water-dispersible form); Cholecalciferol, vitamin d3;  [1] D00188 💬 [1] VDR 💬 [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis  [23]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 162, 202, 228, 271, 298, 299 💬
 17  Cisplatin [1] Cisplatin;  [1] D00275 💬  -  -  [1] 28 💬
 18  Cyclophosphamide [55] Busulfan, cyclophosphamide, antithymocyte globulin; Busulfan, cyclophosphamide, atg; Busulfan, cyclophosphamide, atg, gcsf; Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Campath, fludarabine, cyclophosphamide; Cyclophosphamide; Cyclophosphamide (cy); Cyclophosphamide (cy) (plan 1); Cyclophosphamide (cy) (plan 2); Cyclophosphamide (cytoxan); Cyclophosphamide (drug); Cyclophosphamide + pred; Cyclophosphamide 100mg; Cyclophosphamide 150mg; Cyclophosphamide 30; Cyclophosphamide 40; Cyclophosphamide 50mg; Cyclophosphamide 50mg oral tablet; Cyclophosphamide and atg; Cyclophosphamide and fludarabine; Cyclophosphamide and steroids; Cyclophosphamide dose level 1; Cyclophosphamide dose level 2; Cyclophosphamide dose level 3; Cyclophosphamide dose level 4; Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids; Cyclophosphamide injection 1g; Cyclophosphamide monohydrate; Cyclophosphamide post transplant; Cyclophosphamide(ctx); Cyclophosphamide, azathioprine,prednisone,methylprednisolone; Cyclophosphamide, bortezomib, and dexamethasone (cybord); Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Cyclophosphamide, fludarabine; Cyclophosphamide, fludarabine , thymoglobulin; Cyclophosphamide, fludarabine, rabbit atg; Cyclophosphamide, fludarabine, thymoglobulin; Cyclophosphamide,campath ih and tbi; Cyclophosphamide,cyclosporine a; Cyclophosphamide-prednisone-azathioprine; Cyclophosphamide/glatiramer acetate; Fludarabine, cyclophosphamide; Haploidentical hsct using tbi free regimen, ''atg'' with ''post transplant cyclophosphamide''; High-dose cyclophosphamide; Iv cyclophosphamide; Lenalidomide, dexamethasone and cyclophosphamide; Prednisone and cyclophosphamide; Prednisone plus cyclophosphamide; Prednisone, cyclophosphamide; Prednisone, methylprednisolone,cyclophosphamides; Procedure: cyclophosphamide; Rituximab and cyclophosphamide iv; Thalidomide, cyclophosphamide and prednisone;  [2] D00287
D07760 💬		  -  -  [44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
 19  Cyclosporine [26] Atg+cyclosporine; Atg+rapamune+cyclosporine; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Cyclophosphamide,cyclosporine a; Cyclosporine; Cyclosporine (gengraf ); Cyclosporine (usan); Cyclosporine 5 mg/kg bid days 0-14; Cyclosporine a; Cyclosporine a (csa); Cyclosporine a dry powder inhalation (drug); Cyclosporine combine with mycophenolate mofetil; Cyclosporine inhalation solution; Cyclosporine inhalation solution (cis); Cyclosporine oral product; Cyclosporine pill; Cyclosporine vs infliximab; Cyclosporine-a; Device: cyclosporine a; Liposomal aerosol cyclosporine; Liposomal cyclosporine a; Liposomal cyclosporine a 10 mg; Liposomal cyclosporine a 5 mg; Oral cyclosporine; Rabbit atg, cyclosporine, levamisole; Twice-daily dosage with 0.5% cyclosporine-a eyedrops;  [1] D00184 💬 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 [32] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway  [43] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
 20  Daratumumab [4] Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Daratumumab; Daratumumab co-formulated with recombinant human hyaluronidase (rhuph20); Daratumumab injection;  [1] D10777 💬 [1] CD38 💬 [7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion  [4] 16, 28, 63, 222 💬
 21  Dexamethasone [48] Bortezomib/dexamethasone; Bortezomib/dexamethasone (bd), followed by autologous stc & maintenance bortezomib/dexamethasone; Bupivacaine/epinephrine/dexamethasone; Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine; Control intervention (no dexamethasone); Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cyclophosphamide, bortezomib, and dexamethasone (cybord); Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Device: dexamethasone injection; Dexamethasone; Dexamethasone (1 cycle); Dexamethasone (4 cycles); Dexamethasone (50mg 1dd6, 3 consecutive days/month); Dexamethasone 0,1 mg tablets; Dexamethasone 0,5mg; Dexamethasone 0.5mg tablet; Dexamethasone 0.5mg/5ml solution; Dexamethasone 0.5mg/5ml solution in mucolox™; Dexamethasone 1,5 mg tablets; Dexamethasone 21-dihydrogen phosphate; Dexamethasone 21-phosphate; Dexamethasone 2mg tablets; Dexamethasone 4 mg jenapharm; Dexamethasone abcur; Dexamethasone and rituximab; Dexamethasone oral tablet 8mg (dexamethasone krka tablets(8mg), warsaw, poland).; Dexamethasone parotid irrigation; Dexamethasone sodium phosphate; Dexamethasone sodium phosphate 250 mg/ 10 ml; Dexamethasone sodium phosphate 250 mg/10 ml solution; Dexamethasone sodium phosphate ph. eur.; Dexamethasone sodium sulfate; Dexamethasone soduim phosphate; Dexamethasone, 40 mg; Diagnostic test: dexamethasone test; High dose dexamethasone pulses; Intraarticular dexamethasone; Intravenous dexamethasone 1 mg; Lenalidomide and dexamethasone; Lenalidomide+dexamethasone; Lenalidomide, dexamethasone; Lenalidomide, dexamethasone and cyclophosphamide; Melphalan, thalidomide and dexamethasone; Mmf and dexamethasone; Peri-neural dexamethasone 1 mg; Pomalidomide and dexamethasone; Procedure: epidural steroid (dexamethasone) injection;  [9] D00292
D00975
D01510
D01615
D01632
D01948
D02174
D02591
D02592 💬		 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 162, 222, 235, 283, 296, 299 💬
 22  Dezamizumab [1] Dezamizumab;  [1] D11471 💬  -  -  [1] 28 💬
 23  Diflunisal [2] Diflunisal; Diflunisal (dolobid);  [1] D00130 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway  [1] 28 💬
 24  Doxorubicin [4] 4'-iodo-4'-deoxydoxorubicin; Doxorubicin; Doxorubicin hydrochloride; Liposomal doxorubicin;  [1] D03899 💬 [2] TOP2A, TOP2B 💬 [1] Platinum drug resistance  [4] 26, 28, 34, 331 💬
 25  Doxycycline [10] Antimicrobial therapy: co-trimoxazole or doxycycline; Doxycycline; Doxycycline 100 mg capsules; Doxycycline 100-200mg capsules daily for 6 months; Doxycycline hyclate; Doxycycline hyclate ph.eur; Doxycycline tablets; Interferon beta 1a, oral doxycycline; Other: no doxycycline; Treatment with systemic therapy (doxycycline);  [5] D00307
D02129
D03903
D03904
D07876 💬		  -  -  [15] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 162, 167, 227, 280, 299 💬
 26  Elotuzumab [1] Elotuzumab;  [1] D09337 💬  -  -  [1] 28 💬
 27  Epigallocatechin [7] (2)-epigallocatechin-3-gallate (egcg); Coconut oil and epigallocatechin gallate; Epigallocatechin; Epigallocatechin gallate; Epigallocatechin-3-gallate (egcg); Epigallocatechin-gallate; Epigallocatechin-gallate (sunphenon);  -  -  -  [5]  8 , 13, 28, 85, 113 💬
 28  Epigallocatechin gallate [2] Coconut oil and epigallocatechin gallate; Epigallocatechin gallate;  -  -  -  [9]  6 ,  8 , 13, 17, 28, 85, 113, 206, 299 💬
 29  Etanercept [49] 50 mg etanercept; Adalimuab, etanercept, tocilizumab, or abatacept; Adalimumab, etanercept, golimumab or infliximab; Anti-tnf therapy (etanercept or adalimumab); Bdmard withdrawal (etanercept, adalimumab, infliximab, certolizumab, golimumab, tozilizumab, abatacept); Commercial formulation etanercept; Enbrel (etanercept); Etanercept; Etanercept (50mg per week); Etanercept (50mg per week, for 2 weeks); Etanercept (50mg per week, for 4 weeks); Etanercept (enbrel); Etanercept (enbreltm); Etanercept (etn); Etanercept (full-dose); Etanercept (half-dose); Etanercept + methotrexate; Etanercept , methotrexate; Etanercept / autoinjector a; Etanercept 50 mg sc day 0 and day 3; Etanercept 50 mg/ml; Etanercept 50mg; Etanercept auto-injector; Etanercept biosimilar; Etanercept liquid; Etanercept optimal dosing; Etanercept or adalimumab; Etanercept pre-filled syringe; Etanercept pre-filled syringe sq injection; Etanercept treatment; Etanercept via autoinjector a; Etanercept via autoinjector b; Etanercept, methotrexate and depomedrone; Etanercept, methotrexate, prednisolone; Etanercept, other biologics, disease-modifying antirheumatic drugs (dmards), etc; Infliximab, etanercept; Infliximab, etanercept, adalimumab; Lyophilized etanercept powder(yisaipu); Methotrexate - etanercept - prednisolone arm; New formulation etanercept; Phase 1: etanercept; Prefilled liquid etanercept(yisaipu); Procedure: intra-articular injection of etanercept; Reumatocept (etanercept); Sb4 (etanercept biosimilar); Sb4 (proposed biosimilar to etanercept); Tapering or discontinuation of etanercept; Tnf blockers (infliximab, adalimumab, etanercept); Tumor necrosis factor inhibitor (etanercept, infliximab, adalimumab, and golimumab);  [1] D00742 💬 [2] LTA, TNF 💬 [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬
 30  Etoposide [2] Carmustine, etoposide, cytarabine, and melphalan (beam); Etoposide;  [2] D00125
D04107 💬		 [2] TOP2A, TOP2B 💬 [1] Platinum drug resistance  [11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
 31  Filgrastim [7] Ep2006 (filgrastim); Filgrastim; Filgrastim (g-csf); Filgrastim hexal; Filgrastim, alemtuzumab; Granulocyte colony-stimulating factor (filgrastim); Pegfilgrastim;  [1] D03235 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
 32  Fludarabine [24] Busulfan, cyclophosphamide, thymoglobulin, fludarabine (conditioning regimen); Busulfan, fludarabine and atg; Busulfan, fludarabine, & cyclophosphamide with immunosuppression with atg and cyclosporine.; Busulfan, fludarabine, atg, tli; Busulfan/fludarabine phosphate/tacrolimus/methotrexate/g-csf; Campath, fludarabine, cyclophosphamide; Cyclophosphamide and fludarabine; Cyclophosphamide, fludarabine; Cyclophosphamide, fludarabine , thymoglobulin; Cyclophosphamide, fludarabine, rabbit atg; Cyclophosphamide, fludarabine, thymoglobulin; Fludarabine; Fludarabine (flu); Fludarabine monophosphate; Fludarabine phosphate; Fludarabine phosphate 30 mg; Fludarabine phosphate 40 mg; Fludarabine, busulfan, thymoglobulin; Fludarabine, cyclophosphamide; Fludarabine, melphalan, thiotepa; Fludarabine/ melphalan; Fludarabine/busulfan; Sq fludarabine; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;  [2] D01907
D07966 💬		 [1] RRM1 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism  [18] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬
 33  Foscarnet [2] Foscarnet; Foscarnet sodium;  [2] D00579
D02267 💬		  -  -  [2] 28, 60 💬
 34  Fx-1006A [2] Fx-1006a; Pf-06291826-83/fx-1006a;  -  -  -  [1] 28 💬
 35  Ganciclovir [2] Ganciclovir; Valganciclovir;  [2] D00333
D04301 💬		  -  -  [3] 28, 60, 97 💬
 36  Gelatin [8] Arimoclomol (hard gelatine capsule); Bio-enhanced curcumin soft gelatin capsule; Gelatin; Gelatine; Neoral soft gelatin capsules; Tafamidis meglumine 20 mg soft gelatin capsules; Tafamidis meglumine 20mg soft gelatin capsule (clinical trial image); Tafamidis meglumine 20mg soft gelatin capsule (commerical image);  [2] D00115
D06892 💬		  -  -  [6] 19, 28, 78, 97, 269, 299 💬
 37  Green tea leaf [1] Green tea leaf;  [1] D06903 💬  -  -  [5]  6 , 17, 28, 46, 96 💬
 38  Hyaluronidase [10] Daratumumab co-formulated with recombinant human hyaluronidase (rhuph20); Hyaluronidase; Hyaluronidase injected intradermally; Pegylated recombinant human hyaluronidase ph20; Recombinant human hyaluronidase; Recombinant human hyaluronidase (rhuph20); Recombinant human hyaluronidase (rhuph20)+ immune globulin intravenous (igiv); Recombinant human hyaluronidase + immune globulin intravenous; Recombinant human hyaluronidase ph20; Rituximab or rituximab hyaluronidase human;  [3] D04455
D04456
D06604 💬		  -  -  [4] 28, 51, 65, 331 💬
 39  Hyaluronidase (human recombinant) - -  -  -  [3] 14, 28, 65 💬
 40  Ibrutinib [1] Ibrutinib;  [1] D10223 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency  [3] 28, 60, 61 💬
 41  Imatinib [7] Bevacizumab (avastin) and imatinib mesylate (gleevec); Imatinib; Imatinib mesilate; Imatinib mesilato; Imatinib mesylate; Imatinib mesylate (gleevec); Imatinib mesylate 400mg capsule;  [2] D01441
D08066 💬		 [3] ABL1, KIT, PDGFRA 💬 [31] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis  [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
 42  Indium [6] Indium; Indium 111-radiolabelled anti-cd66; Indium-111 pentreotide; Indium-dtpa; Indium­ 111 ­labelled anti­-cd66; Other: technetium [tc-99m] sulfur colloid and indium [in-111] dtpa;  -  -  -  [3] 28, 84, 299 💬
 43  Inotersen [1] Inotersen;  [1] D10940 💬 [1] TTR 💬 [1] Thyroid hormone synthesis  [1] 28 💬
 44  Interferon alfa [5] Interferon alfa; Interferon alfa-2a; Interferon alfa-2b; Pegylated interferon alfa; Recombinant interferon alfa;  [1] D03305 💬 [2] IFNAR1, IFNAR2 💬 [18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway  [6] 13, 25, 26, 28, 56, 96 💬
 45  Iodine [2] Iodine; Radiation: computed tomography lung subtraction iodine mapping;  [1] D00108 💬  -  -  [3] 28, 46, 88 💬
 46  Isatuximab [2] Isatuximab; Isatuximab sar650984;  [1] D11050 💬 [1] CD38 💬 [7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion  [2] 28, 61 💬
 47  Ixazomib [3] Ixazomib; Ixazomib (ninlaro®) capsules; Ixazomib citrate;  [1] D10130 💬 [1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia  [4] 13, 16, 28, 61 💬
 48  Lenalidomide [6] Lenalidomide; Lenalidomide 25mg; Lenalidomide and dexamethasone; Lenalidomide+dexamethasone; Lenalidomide, dexamethasone; Lenalidomide, dexamethasone and cyclophosphamide;  [1] D04687 💬 [1] TNF 💬 [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [7] 16, 26, 28, 34, 49, 284, 300 💬
 49  Meglumine [6] Meglumine; Procedure: mri imaging with intravenous contrast with gadoterate meglumine; Tafamidis meglumine; Tafamidis meglumine 20 mg soft gelatin capsules; Tafamidis meglumine 20mg soft gelatin capsule (clinical trial image); Tafamidis meglumine 20mg soft gelatin capsule (commerical image);  [1] D01796 💬  -  -  [2] 28, 53 💬
 50  Melphalan [10] Carmustine, etoposide, cytarabine, and melphalan (beam); Fludarabine, melphalan, thiotepa; Fludarabine/ melphalan; Melphalan; Melphalan fulfenamide hydrochloride; Melphalan hydrochloride; Melphalan, thalidomide and dexamethasone; Melphalan-flufenamide (melflufen); Propylene glycol-free melphalan hydrochloride; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;  [1] D00369 💬  -  -  [15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
 51  Miridesap [1] Miridesap;  [1] D11464 💬  -  -  [1] 28 💬
 52  Mycophenolate mofetil [19] Azathioprine or mycophenolate mofetil; Cellcept (mycophenolate mofetil); Cyclosporine combine with mycophenolate mofetil; Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate); Mycophenolate mofetil; Mycophenolate mofetil (cellcept); Mycophenolate mofetil (mmf); Mycophenolate mofetil (mmf) 3 g/day; Mycophenolate mofetil 2 g/day; Mycophenolate mofetil [cellcept]; Mycophenolate mofetil orally 1000 mg twice a day (bid); Mycophenolate mofetil plus lower dose of prednisone; Mycophenolate mofetil(mmf); Mycophenolate mofetil, low dose steroid; Mycophenolate mofetil,methotrexate; Prednisolone and mycophenolate mofetil; Prednisone and mycophenolate mofetil; Prednisone, ciclosporin and mycophenolate mofetil; Symptomatic treatment, steroids, immunosuppressive agents( azathioprine, tacrolimus, mycophenolate mofetil);  [3] D00752
D05094
D05095 💬		 [2] IMPDH1, IMPDH2 💬 [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [32]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
 53  Mycophenolic acid [2] Mycophenolic acid; Mycophenolic acid mofetil;  [1] D05096 💬 [2] IMPDH1, IMPDH2 💬 [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism  [34]  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
 54  Pentetic acid - [1] D05422 💬  -  -  [2] 28, 299 💬
 55  Phosphate ion - -  -  -  [30]  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬
 56  Pomalidomide [5] Pomalidomide; Pomalidomide (cc-4047; Pomalidomide (cc-4047); Pomalidomide and dexamethasone; Pomalidomide oral product;  [1] D08976 💬 [2] IL6, TNF 💬 [78] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [6] 28, 34, 51, 85, 227, 331 💬
 57  Propylene glycol [3] 10% nitroglycerine in propylene glycol, usp; Propylene glycol; Propylene glycol-free melphalan hydrochloride;  [1] D00078 💬  -  -  [2] 28, 51 💬
 58  Pyrazole [2] (r)-n-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1h-inden-1-yl)-1-methyl-1h-pyrazole-4-carboxamide; Pyrazole;  -  -  -  [4] 28, 46, 58, 75 💬
 59  Revusiran [1] Revusiran;  -  -  -  [1] 28 💬
 60  Sargramostim [4] Gm-csf (granulocyte-macrophage colony-stimulating factor, sargramostim); Gm-csf [leukine (sargramostim)]; Sargramostim; Sargramostim (leukine);  [1] D05803 💬 [1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer  [7]  6 , 28, 60, 62, 96, 229, 285 💬
 61  Siltuximab [1] Siltuximab;  [1] D09669 💬 [1] IL6 💬 [49] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection  [2] 28, 331 💬
 62  Sodium sulfate [2] Dexamethasone sodium sulfate; Sodium sulfate;  [2] D01732
D05877 💬		  -  -  [1] 28 💬
 63  Sorbitol [2] D-sorbitol; Sorbitol;  [1] D00096 💬  -  -  [4]  6 , 10, 28, 299 💬
 64  Sulfate ion - -  -  -  [25]  2 ,  6 , 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 222, 226, 265, 296, 297, 299 💬
 65  Sunitinib [3] Sunitinib; Sunitinib malate; Sutent®/sunitinib;  [2] D06402
D08552 💬		 [9] CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB, RET 💬 [39] Acute myeloid leukemia, Alzheimer disease, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, TNF signaling pathway, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor  [2] 28, 34 💬
 66  Tafamidis [5] Tafamidis; Tafamidis meglumine; Tafamidis meglumine 20 mg soft gelatin capsules; Tafamidis meglumine 20mg soft gelatin capsule (clinical trial image); Tafamidis meglumine 20mg soft gelatin capsule (commerical image);  [1] D09673 💬 [1] TTR 💬 [1] Thyroid hormone synthesis  [1] 28 💬
 67  Thalidomide [10] Fpf 300 (thalidomide); Melphalan, thalidomide and dexamethasone; Thalidomide; Thalidomide (drug); Thalidomide 100mg; Thalidomide 150mg; Thalidomide celgene - 50 mg capsula rigida - uso orale - blister (pvc/pe/aclar/alu) 28 capsule; Thalidomide celgene*28cps 50mg; Thalidomide pharmion; Thalidomide, cyclophosphamide and prednisone;  [1] D00754 💬 [1] TNF 💬 [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
 68  Thiotepa [5] Fludarabine, melphalan, thiotepa; Thiotepa; Thiotepa--escalated dose; Thiotepa--single daily dose; Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan;  [1] D00583 💬  -  -  [11] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284 💬
 69  Tolcapone [1] Tolcapone;  [1] D00786 💬 [1] COMT 💬 [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism  [3]  6 , 28, 127 💬
 70  Valganciclovir [3] Valganciclovir; Valganciclovir (vgc); Valganciclovir [valcyte];  [1] D02495 💬  -  -  [6] 28, 60, 85, 97, 299, 331 💬
 71  Venetoclax [1] Venetoclax;  [1] D10679 💬 [1] BCL2 💬 [41] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Cholinergic synapse, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway  [1] 28 💬
 72  Yttrium Y-90 - -  -  -  [1] 28 💬