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29 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Acetate [98] 11c-acetate; 2-(2-(2-amino-9h-purin-9-yl)ethyl)-1,3-propanediol diacetate ester; 20mg/0.5ml glatiramer acetate; 40 mg glatiramer acetate; 90 mg hydrocortisone acetate suppository with sephure suppository applicator; Abiraterone acetate; Acetate; Bazedoxifene acetate; Betamethasone sodium phosphate/betamethasone acetate (celestone® soluspan®), 30 mg im once a day for four days; Caspofungin acetate; Combination product: twice daily 90 mg hydrocortisone acetate suppository administered with sephure applicator; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortisone acetate; Cosyntropin acetate; Cyclophosphamide/glatiramer acetate; Delmitide acetate; Depot leuprolide acetate 3.75 mg; Desmopressin acetate; Desmopressin acetate trihydrate; Device: cellulose acetate with petrolatum; Dichloroacetate; Dichloroacetate sodium; Dirucotide acetate; Edratide acetate; Etiprednol dicloacetate; Experimental glatiramer acetate; Flecainide acetate; Glatiramer acetate; Glatiramer acetate (copaxone®); Glatiramer acetate (db); Glatiramer acetate (ga); Glatiramer acetate (ga) 40 mg; Glatiramer acetate (gtr); Glatiramer acetate (ol); Glatiramer acetate 150mg enteric coated tablets; Glatiramer acetate 150mg enteric-coated (gastro-resistant) tablets; Glatiramer acetate 20 mg; Glatiramer acetate 20 mg, with mitoxantrone; Glatiramer acetate 20 mg/0.5 ml; Glatiramer acetate 40 mg; Glatiramer acetate [ga]; Glatiramer acetate injection with oral cetirizine hydrochloride; Glatiramer acetate with minocycline; Glatiramer acetate, (copaxone®); Glatiramer acetate, ifn-beta 1a (im), ifn-beta 1a (subcutaneous), and ifn-beta 1b; Glatiramer acetate, n-acetylcysteine; Gonadorelin acetate and triptorelin acetate; Human interferon beta-1a and glatiramer acetate; Hydrocortisone acetate; Hydrocortisone sodium acetate; L-lysyl-d-prolyl-l-threonine acetate; L-lysyl-d-prolyl-lthreonine acetate, lyophilisate; Lanreotide acetate; Lapaquistat acetate and current lipid-lowering treatment; Leuprolide acetate (la); Leuprolide acetate 11.25 mg; Leuprolide acetate 3 month depot; Leuprolide acetate 30 mg; Leuprolide acetate 45 mg; Leuprolide acetate depot; Leuprorelin acetate; Leuprorelin acetate 3.75mg injection; Loestrin (norethindrone acetate and ethinyl estradiol); Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol); Luphere depot 3.75mg(leuprolide acetate 3.75mg); Lupron (leuprolide acetate); Macimorelin acetate; Megestrol acetate; Megestrol acetate tablet; Methylprednisolone acetate; Nomegestrol acetate; Octreotide acetate; Oxaloacetate (oaa); Phosphate and betamethasone acetate, 2 ml.; Plovamer acetate; Plovamer acetate 0.5 milligram (mg); Plovamer acetate 10 mg; Plovamer acetate 20 mg; Plovamer acetate 3 mg; Prednisolone acetate; Prednisone acetate; Prednisone acetate tablets; Procedure: warm compress prior to injection of glatiramer acetate; Sodium acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]- phenyl]-acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]-phenyl]-acetate; Sotrastaurin (inn) acetate; Tetracosactide acetate; Tetracosactide hexaacetate; Tocopherol acetate; Tocopheryl acetate; Triptorelin acetate and gonadorelin acetate; Ulipristal acetate; Zinc acetate; Zinc acetate (20mg/d); Zinc acetate dihydrate; Zuretinol acetate; [n-trans-3-hexenoyl] human growth hormone releasing factor (1-44) acetate;  -  -  [43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬
 2  Alirocumab [2] Alirocumab; Alirocumab sar236553 (regn727);  [1] D10335 💬 [1] PCSK9 💬 [1] Cholesterol metabolism  [1] 79 💬
 3  Anacetrapib [1] Anacetrapib;  [1] D08855 💬 [1] CETP 💬 [1] Cholesterol metabolism  [1] 79 💬
 4  Atorvastatin [9] Atorvastatin; Atorvastatin 10mg; Atorvastatin 20mg; Atorvastatin calcium; Atorvastatin tablet 20 mg; Interferon beta treatment to add-on atorvastatin treatment; Interferon beta-1b/atorvastatin group; Lisinopril, losartan, and atorvastatin; Untreated to atorvastatin treatment;  [3] D00258
D00887
D07474 💬
[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬
 5  Calcium [34] Amorphous calcium carbonate; Ascal(r) / carbasalate calcium; Atorvastatin calcium; Calcitriol & calcium; Calcium; Calcium and cholecalciferol; Calcium and vitamin d combination; Calcium carbonate; Calcium carbonate and alphacalcidol; Calcium carbonate d; Calcium channel blockers; Calcium citrate; Calcium citrate with vitamin d2; Calcium gluconate; Calcium lactate; Calcium levofolinate; Calcium rosuvastatin; Calcium, dietary; Carbasalate calcium; Crestor tablets (calcium rosuvastatin) film-coated tablets; Crystalline calcium supplements; Ethylhydrogenfumarat, calciumsalz; Ibandronate+alfacalcidol+calcium; Low molecular weight heparin calcium injection; Other: calcium stable isotope; Other: determination of calcium intake by a dietician interview; Other: empiric use of calcium carbonate and calcitriol; Other: pth based calcium carbonate and calcitriol repletion; Other: serum calcium concentrations results; Rosuvastatin calcium; Rosuvastatin calcium 40mg; Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin); Vidofludimus calcium; Vidofludimus calcium dihydrate;  -  -  [27]  6 , 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
 6  Cholestyramine [1] Cholestyramine;  -  -  [3] 13, 79, 254 💬
 7  Dextran [7] Device: dextran sulfate adsorption; Dextran; Dextran 1 for injection; Dextran sodium sulfur salt 5, mw 5 kda. a type of low molecular weight dextran sulfate (lmw-ds); Dextran sulfate sodium; Iron dextran; Iron(iii)- hydroxide dextran complex;  [1] D00060 💬  -  [5]  2 , 62, 79, 96, 97 💬
 8  Evinacumab [2] Evinacumab; Evinacumab (regn1500);  [1] D11753 💬 [1] ANGPTL3 💬 [1] Cholesterol metabolism  [1] 79 💬
 9  Evolocumab [3] Evolocumab; Evolocumab (amg 145); Repatha (evolocumab);  [1] D10557 💬 [1] PCSK9 💬 [1] Cholesterol metabolism  [2] 79, 222 💬
 10  Ezetimibe [5] Comparator: ezetimibe; Ezetimibe; Ezetimibe + other lipid-lowering medication(s); Ezetimibe+simvastatin drug combination; Mk0653, ezetimibe;  [1] D01966 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption  [4] 49, 79, 93, 260 💬
 11  Fenofibrate [2] Fenofibrate; Fenofibrate idd-p (insoluble drug delivery-micro particle);  [1] D00565 💬 [1] PPARA 💬 [8] Adipocytokine signaling pathway, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway  [5]  8 , 79, 93, 94, 265 💬
 12  Fluvastatin [2] Benazepril, valsartan and fluvastatin; Fluvastatin;  [2] D00892
D07983 💬
[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [3] 79, 218, 222 💬
 13  Gemcabene [3] 300mg gemcabene; 600mg gemcabene; Gemcabene;  -  -  [2] 79, 265 💬
 14  Glycerin [2] Glycerine; Other: glycerine gel;  [1] D00028 💬  -  [6]  6 , 13, 79, 265, 316, 317 💬
 15  Heparin [9] Alkalinized lidocaine-heparin; Bladder instillation with heparin/ lidocaine; Device: heparin-induced extracorporeal ldl precipitation; Heparin; Heparin & alkalinized lidocaine bladder instillation; Heparin 25mg inhalation powder, hard capsule; Heparin sodium; Intralipid/heparin; Low molecular weight heparin calcium injection;  [1] D07510 💬 [1] SERPINC1 💬 [1] Complement and coagulation cascades  [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬
 16  Implitapide [1] Implitapide;  -  -  [1] 79 💬
 17  Inclisiran [3] Inclisiran; Inclisiran for injection; Inclisiran sodium;  [1] D11931 💬 [1] PCSK9 💬 [1] Cholesterol metabolism  [1] 79 💬
 18  Lapaquistat [2] Lapaquistat; Lapaquistat acetate and current lipid-lowering treatment;  -  -  [1] 79 💬
 19  Lomitapide [2] Lomitapide; Lomitapide 2mg hard capsules;  [1] D09637 💬 [1] MTTP 💬 [1] Fat digestion and absorption  [1] 79 💬
 20  Lovastatin [5] Lovastatin; Lovastatin 60 mg; Lovastatin ™; Lovastatin, then minocycline/lovastatin; Minocycline, then minocycline/lovastatin;  [1] D00359 💬 [1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
 21  MBX-8025 [12] Experimental: seladelpar / mbx-8025 200 mg; Experimental: seladelpar / mbx-8025 50 mg; Mbx 8025; Mbx-8025; Mbx-8025 10 mg capsule; Mbx-8025 2 mg capsule; Mbx-8025 5 mg capsule; Mbx-8025 50 mg (dose escalation period 1); Mbx-8025 50 mg or 100 mg (dose escalation period 2); Mbx-8025 50 mg, 100 mg or 200 mg (dose escalation period 3); Mbx-8025, dsic; Mbx-8025, formulation 2;  -  -  [3] 79, 93, 94 💬
 22  Mipomersen [1] Mipomersen;  [1] D08946 💬  -  [1] 79 💬
 23  Niacin [6] Dose-establishing study 1 niacin 250mg; Dose-establishing study 1 niacin 500mg; Dose-establishing study 2 niacin 500mg; Niacin; Niacin first; Niacinamide;  [1] D00049 💬  -  [4]  6 , 78, 79, 265 💬
 24  Omega-3 fatty acids [3] Lipoic acid and omega-3 fatty acids; Omega-3 fatty acids; Triomar™ (omega-3 fatty acids);  -  -  [7] 13, 46, 49, 66, 79, 96, 299 💬
 25  Pravastatin [5] Lonafarnib, zoledronic acid, and pravastatin; Montelukast, flurbiprofen, midazolam, digoxin, pravastatin and bms-986142; Pravastatin; Pravastatin sodium; Zoledronic acid, pravastatin;  [2] D00893
D08410 💬
[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
 26  Rosuvastatin [8] Calcium rosuvastatin; Crestor tablets (calcium rosuvastatin) film-coated tablets; Rosuvastatin; Rosuvastatin 10 mg; Rosuvastatin 20mg; Rosuvastatin calcium; Rosuvastatin calcium 40mg; Rosuvastatine eg;  [2] D01915
D08492 💬
[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
 27  Simvastatin [21] Encapsulated simvastatin tablets; Ezetimibe+simvastatin drug combination; Other: simvastatin; Simvastatin; Simvastatin 20 mg; Simvastatin 20mg/5ml oral suspension; Simvastatin 40 mg; Simvastatin 40 mg film-coated tablets; Simvastatin 40 mg tablets; Simvastatin 40mg; Simvastatin alternova; Simvastatin in relapsing remitting multiple sclerosis; Simvastatin susp.; Simvastatin treatment for 28 days; Simvastatin-ratiopharm; Simvastatin-ratiopharm®; Simvastatina; Simvastatina sandoz 40 mg comprimidos recubiertos con película efg; Simvastatine; Simvastatine sandoz 40 mg filmomhulde tabletten; Simvastatine sandoz 40mg deelbare filmomhulde tabletten;  [1] D00434 💬 [1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
 28  Sulfate ion -  -  [25]  2 ,  6 , 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 222, 226, 265, 296, 297, 299 💬
 29  TAK-475 [1] Tak-475;  -  -  [1] 79 💬