DDrare: Database of Drug Development for Rare Diseases

Searched query = "Wilson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 64CuCl2; ALXN1840; Acetate; Artamin 150 mg; Artamin 250 mg; BIS-CHOLINE TETRATHIOMOLYBDATE; Bis-Choline Tetrathiomolybdate; Bis-choline TETRATHIOMOLYBDATE; Bupropion; Bupropion Hydrochloride; COPPER (64CU) CHLORIDE; Celecoxib; Chloride; Choline; Copper; Cuprior; Cuprior 150 mg film-coated tablets; Cuprior 150mg film-coated tablets; D-penicillamine; D-penicillamine 150mg; D-penicillamine 250 mg; DMPS; DMSA; Galactose; Gold; Metalcaptase® 150 mg gastro-resistant tablet; Metalcaptase® 300 mg gastro-resistant tablet; NPC-02; Nitrogen; None; Once a day Trientine; PEMINE - 150 MG CAPSULE RIGIDE 50 CAPSULE; PENICILLAMINE; Penicillamine; Procedure: Fibroscan; Procedure: Functional hepatic nitrogen clearance; Procedure: Liver biopsy; Procedure: Ultrasound; SoC Therapy; Standard of Care Medications; TETA; TETA 4HCL; TETA 4HCl; TETA.4HCI; TETA.4HCl; TRIENTINE DIHYDROCHLORIDE; Tetrathiomolybdate; Trientine; Trientine dihydrochloride; Trientine dihydrochloride 300mg capsules; Trientine tetrahydrochloride; WTX101; Wilzin; ZINC ACETATE DIHYDRATE; ZINC GLUCONATE; Zinc; Zinc acetate; Zinc gluconate; Zink Natur-Drogeriet

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2016-003876-29-DE (EUCTR)	15/09/2017	03/04/2017	Chelate Study: Trientine for the treatment of Wilson's disease	CHELATE STUDY: Trientine tetrahydrochloride (TETA 4HCl) for the treatment of Wilson’s disease	Wilson's disease (WD) is a life-threatening inborn error of copper metabolism leading to an excessive copper accumulation, mainly in the liver or brain, causing hepatic and neurologic severe symptoms. MedDRA version: 20.0;Level: LLT;Classification code 10047988;Term: Wilson's disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]	Trade Name: Cuprior 150 mg film-coated tablets Product Name: TETA 4HCl Product Code: TETA 4HCl INN or Proposed INN: Trientine tetrahydrochloride Other descriptive name: TETA 4HCl Trade Name: Metalcaptase® 150 mg gastro-resistant tablet INN or Proposed INN: penicillamine Other descriptive name: penicillamine Trade Name: Metalcaptase® 300 mg gastro-resistant tablet INN or Proposed INN: penicillamine Other descriptive name: penicillamine	gmp-orphan SA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	55	Phase 3	Brazil;Belgium;Denmark;Austria;Germany;United Kingdom;United States;France;Poland;Italy;Sweden

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

EUCTR2016-003876-29-DE
(EUCTR)

15/09/2017

03/04/2017

Chelate Study: Trientine for the treatment of Wilson's disease

CHELATE STUDY: Trientine tetrahydrochloride (TETA 4HCl) for the treatment of Wilson’s disease

Wilson's disease (WD) is a life-threatening inborn error of copper metabolism leading to an excessive copper accumulation, mainly in the liver or brain, causing hepatic and neurologic severe symptoms.
MedDRA version: 20.0;Level: LLT;Classification code 10047988;Term: Wilson's disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]

Trade Name: Cuprior 150 mg film-coated tablets
Product Name: TETA 4HCl
Product Code: TETA 4HCl
INN or Proposed INN: Trientine tetrahydrochloride
Other descriptive name: TETA 4HCl
Trade Name: Metalcaptase® 150 mg gastro-resistant tablet
INN or Proposed INN: penicillamine
Other descriptive name: penicillamine
Trade Name: Metalcaptase® 300 mg gastro-resistant tablet
INN or Proposed INN: penicillamine
Other descriptive name: penicillamine

gmp-orphan SA

NULL

Authorised-recruitment may be ongoing or finished

Female: yes
Male: yes

Phase 3

Brazil;Belgium;Denmark;Austria;Germany;United Kingdom;United States;France;Poland;Italy;Sweden