205. Fragile X syndrome related disease
3 clinical trials, 3 drugs (DrugBank: 2 drugs), 21 drug target genes, 25 drug target pathways
Searched query = "Fragile X syndrome related disease", "Fragile X-associated tremor/ataxia syndrome", "FXTAS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02603926 (ClinicalTrials.gov) | October 2015 | 5/11/2015 | Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone | Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone | Fragile X-associated Tremor/Ataxia Syndrome | Drug: Allopregnanolone | Randi J. Hagerman, MD | NULL | Completed | 50 Years | 85 Years | All | 6 | Phase 2 | United States |
| 2 | NCT02197104 (ClinicalTrials.gov) | January 2015 | 14/7/2014 | Citocoline for Treatment of FXTAS | Phase 2 Study of Citocoline for Treatment in Fragile X-associated Tremor/Ataxia Syndrome | Balance and Cognitive Deficits in Fragile X-associated Tremor Ataxia Syndrome | Drug: citocoline | Rush University Medical Center | NULL | Completed | 18 Years | 90 Years | All | 10 | Phase 2 | United States |
| 3 | NCT00584948 (ClinicalTrials.gov) | September 2007 | 22/12/2007 | Memantine Treatment in Fragile X-Associated Tremor/Ataxia Syndrome | Characterization and Treatment of CNS Abnormalities in Premutation Carriers: A Double-Blind Placebo-Controlled Trial of Memantine | Fragile X-Associated Tremor/Ataxia Syndrome;Fragile X Premutation Carriers | Drug: Memantine;Drug: Placebo | University of California, Davis | National Institute on Aging (NIA);Forest Laboratories | Completed | 30 Years | 80 Years | All | 94 | N/A | United States |