228. Bronchiolitis obliterans
92 clinical trials,   125 drugs   (DrugBank: 34 drugs),   33 drug target genes,   152 drug target pathways
Searched query = "Bronchiolitis obliterans", "Obliterating bronchiolitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT03315741 (ClinicalTrials.gov) | March 1, 2018 | 5/10/2017 | The Safety and Tolerability of Pirfenidone for BOS After HCT | The Safety and Tolerability of Pirfenidone for Bronchiolitis Obliterans Syndrome After Hematopoietic Cell Transplantation | Bronchiolitis Obliterans;Graft Vs Host Disease | Drug: Pirfenidone 267 MG [Esbriet] | Stanford University | Genentech, Inc. | Recruiting | 18 Years | N/A | All | 30 | Phase 1 | United States |
2 | EUCTR2014-002022-12-SE (EUCTR) | 06/08/2015 | 15/10/2014 | European Trial of Pirfenidone in BOS (EPOS). | A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial | Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s). MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Trade Name: Esbriet Product Name: Pirfenidone INN or Proposed INN: PIRFENIDONE Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone | Clinical Trials Unit, Rigshospitalet | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 80 | Phase 2 | Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden | ||
3 | EUCTR2014-002022-12-NL (EUCTR) | 13/05/2015 | 03/11/2014 | European Trial of Pirfenidone in BOS (EPOS). | A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial | Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s). MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855 ;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Clinical Trials Unit, Rigshospitalet | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 80 | Phase 2 | Belgium;Denmark;Germany;Netherlands;United Kingdom;Sweden | |||
4 | NCT02262299 (ClinicalTrials.gov) | May 2015 | 21/9/2014 | European Trial of Pirfenidone in BOS, A European Multi-center Study | A European Multi-center, Randomised, Double-blind Trial of Pirfenidone in Bronchiolitis-obliterans-syndrome Grade 1-3 in Lung Transplant Recipients | Disorder Related to Lung Transplantation;CLAD, Bronchiolitis Obliterans | Drug: Pirfenidone;Drug: Placebo | Rigshospitalet, Denmark | NULL | Completed | 18 Years | N/A | All | 90 | Phase 2;Phase 3 | Belgium;Denmark;Germany;Netherlands;Norway;Sweden;United Kingdom |
5 | EUCTR2014-002022-12-BE (EUCTR) | 10/03/2015 | 15/10/2014 | European Trial of Pirfenidone in BOS (EPOS). | A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial | Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s). MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000015490;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Trade Name: Esbriet Product Name: Pirfenidone INN or Proposed INN: PIRFENIDONE Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone | Clinical Trials Unit, Rigshospitalet | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 80 | Phase 2 | Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden | ||
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
6 | EUCTR2014-002022-12-GB (EUCTR) | 06/01/2015 | 15/10/2014 | European Trial of Pirfenidone in BOS (EPOS). | A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial | Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s). MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855 ;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Clinical Trials Unit, Rigshospitalet | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden | |||
7 | EUCTR2014-002022-12-DE (EUCTR) | 30/12/2014 | 21/10/2014 | European Trial of Pirfenidone in BOS (EPOS). | A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial | Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s). MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855 ;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Clinical Trials Unit, Rigshospitalet | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 80 | Phase 2 | Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden | |||
8 | EUCTR2014-002022-12-DK (EUCTR) | 15/12/2014 | 04/11/2014 | European Trial of Pirfenidone in BOS (EPOS). | A European multi-centre, randomised, double-blind trial of pirfenidone in bronchiolitis-obliterans-syndrome grade 1-3 in lung transplant recipients. - EPOS Trial | Bronchiolitis Obliterans Syndrome (BOS) in patients following lung transplantation. This syndrome occurs due to rejection of the transplanted organ (s). MedDRA version: 20.0;Level: LLT;Classification code 10049202;Term: Bronchiolitis obliterans;System Organ Class: 100000004855;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Trade Name: Esbriet Product Name: Pirfenidone INN or Proposed INN: PIRFENIDONE Other descriptive name: 5-Methyl-1-Phenyl-2-1-(H)-Pyridone | Clinical Trials Unit, Rigshospitalet | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 90 | Phase 2 | Belgium;Denmark;Netherlands;Germany;United Kingdom;Sweden |