70. Spinal stenosis
91 clinical trials, 195 drugs (DrugBank: 54 drugs), 60 drug target genes, 85 drug target pathways
Searched query = "Spinal stenosis", "Extensive spinal canal stenosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03245671 (ClinicalTrials.gov) | December 2017 | 7/8/2017 | Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis | Particulate vs. Nonparticulate Epidural Steroid Injections for the Treatment of Symptomatic Unilateral Lumbar Foraminal Stenosis: a Prospective Double-blinded Randomized Study | Lumbar Spinal Stenosis | Drug: Kenalog Injectable Product;Drug: Decadron Phosphate, Injectable;Procedure: Epidural Steroid Injection | Hospital for Special Surgery, New York | NULL | Withdrawn | 18 Years | 90 Years | All | 0 | Phase 4 | United States |
| 2 | NCT02939482 (ClinicalTrials.gov) | October 1, 2016 | 15/10/2016 | A Study Comparison of Clinical Outcome After Different Rate of Infusion in Caudal Epidural Steroid Injection | A Prospective Study Comparison of Clinical Outcome After Different Rate Infusion in Caudal Epidural Steroid Injection | Spinal Stenosis;Lumbosacral Spondylosis;Radiculopathy | Drug: Triamcinolone Acetonide and normal saline solution | Navamindradhiraj University | NULL | Completed | 20 Years | N/A | All | 112 | N/A | Thailand |
| 3 | NCT02838615 (ClinicalTrials.gov) | July 2016 | 25/5/2016 | Comparison of Transforaminal vs. Parasagittal Interlaminar Epidural Injection | Comparison of Lumbar Epidural Steroid Injection: Transforaminal vs. Parasagittal Interlaminar Approach | Spinal Stenosis | Procedure: epidural steroid (dexamethasone) injection | Keimyung University Dongsan Medical Center | NULL | Completed | N/A | N/A | All | 56 | N/A | NULL |
| 4 | NCT02093520 (ClinicalTrials.gov) | May 2014 | 18/3/2014 | The MiDAS ENCORE Study | MILD® Percutaneous Image-Guided Lumbar Decompression Versus Epidural Steroid Injections in Patients With Lumbar Spinal Stenosis Exhibiting Neurogenic Claudication | Spinal Stenosis, Lumbar Region, With Neurogenic Claudication | Procedure: MILD Procedure;Drug: Epidural Steroid Injection | Vertos Medical, Inc. | NULL | Completed | 65 Years | N/A | All | 302 | N/A | United States |
| 5 | NCT02103543 (ClinicalTrials.gov) | January 2014 | 27/3/2014 | Comparison of the Order of Treatment in Lumbar Spinal Stenosis | A Randomized Trial in Patients With Lumbar Spinal Stenosis, Comparing the Order of Treatment With Epidural Corticosteroid Injections and Physical Therapy | Lumbar Spinal Stenosis | Other: physical therapy;Procedure: lumbar interlaminar epidural steroid injection;Drug: epidural steroid injection | Emory University | NULL | Withdrawn | 18 Years | 65 Years | All | 0 | N/A | United States |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT01934868 (ClinicalTrials.gov) | December 1, 2013 | 30/8/2013 | Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg | A Comparison of the Long Term Outcomes of Prolotherapy Versus Interlaminar Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg | Sciatica;Spinal Stenosis of Lumbar Region;Degeneration of Lumbar or Lumbosacral Intervertebral Disc | Drug: prolotherapy solution of 20% dextrose;Drug: Epidural Steroid Injection | Hadassah Medical Organization | Reuth Rehabilitation Hospital | Active, not recruiting | 18 Years | 90 Years | All | 110 | Phase 4 | Israel |
| 7 | NCT01995461 (ClinicalTrials.gov) | May 2013 | 18/11/2013 | Bilateral Transforaminal Epidural Steroid Injections for Degenerative Lumbar Spinal Stenosis | Effectiveness of Bilateral Transforaminal Epidural Steroid Injections in Degenerative Lumbar Spinal Stenosis Patients With Neurogenic Claudication: A Prospective Outcome Study | Spinal Stenosis, Lumbar Region, With Neurogenic Claudication | Drug: bilateral transforaminal epidural steroid injections | Marshfield Clinic Research Foundation | NULL | Terminated | 40 Years | 90 Years | All | 26 | N/A | United States |
| 8 | NCT01238536 (ClinicalTrials.gov) | April 2011 | 8/11/2010 | Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial) | Multicenter Randomized Controlled Trial of Epidural Steroid Injections for Spinal Stenosis in Persons 50 and Older | Spinal Stenosis;Low Back Pain | Procedure: Epidural steroid with local anesthetic injection;Procedure: Epidural local anesthetic injection;Drug: Epidural steroid injection;Drug: Epidural local anesthetic injection | University of Washington | Kaiser Permanente;University of California, San Francisco;Henry Ford Hospital;Harvard Pilgrim Health Care;Harvard Vanguard Medical Associates;University of Colorado, Denver;Mayo Clinic;Stanford University;Massachusetts General Hospital;Virginia Spine Research Institute;Oregon Health and Science University;Dallas VA Medical Center | Completed | 50 Years | N/A | All | 400 | Phase 4 | United States |
| 9 | NCT01315145 (ClinicalTrials.gov) | March 2011 | 11/3/2011 | MiDAS III (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study | MiDAS III (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study | Lumbar Spinal Stenosis | Procedure: Percutaneous Lumbar Decompression;Drug: Epidural Steroid Injection | Vertos Medical, Inc. | NULL | Completed | 50 Years | N/A | All | 138 | N/A | United States |
| 10 | NCT00995371 (ClinicalTrials.gov) | August 2009 | 14/10/2009 | Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis | Comparative Study of Epidural Steroid Injection Versus Mild® (Minimally Invasive Lumbar Decompression) Procedure in Patients Diagnosed With Symptomatic Moderate to Severe Lumbar Central Canal Stenosis | Lumbar Spinal Stenosis | Device: MILD® (Minimally Invasive Lumbar Decompression);Drug: Epidural Steroid Injection | Coastal Orthopedics & Sports Medicine | Vertos Medical, Inc. | Completed | 18 Years | N/A | All | 38 | Phase 4 | United States |