Pln-74809 (DrugBank: -)
2 diseases| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 85 | 特発性間質性肺炎 | 4 |
| 94 | 原発性硬化性胆管炎 | 2 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2019-002709-23-DE (EUCTR) | 18/12/2020 | 31/01/2020 | A study to assess the efficacy, safety and pharmacokinetics of PLN-74809 inparticipants with idiopathic pulmonary fibrosis | A randomized, double-blind, dose-ranging, placebo-controlled Phase 2aevaluation of the safety, tolerability and pharmacokinetics of PLN-74809 inparticipants with idiopathic pulmonary fibrosis (IPF) (INTEGRIS-IPF) | Idiopathic pulmonary fibrosis (IPF) MedDRA version: 21.1;Level: PT;Classification code 10021240;Term: Idiopathic pulmonary fibrosis;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not Available Other descriptive name: PLN-74809-000 | Pliant Therapeutics Inc. | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 84 | Phase 2 | United States;France;Canada;Belgium;Australia;Netherlands;Germany;United Kingdom;New Zealand;Italy | ||
| 2 | EUCTR2019-002709-23-GB (EUCTR) | 06/11/2020 | 24/01/2020 | A study to assess the efficacy, safety and pharmacokinetics of PLN-74809 in participants with idiopathic pulmonary fibrosis | A randomized, double-blind, dose-ranging, placebo-controlled Phase 2a evaluation of the safety, tolerability and pharmacokinetics of PLN-74809 in participants with idiopathic pulmonary fibrosis (IPF) (INTEGRIS-IPF) | Idiopathic pulmonary fibrosis (IPF) MedDRA version: 21.1;Level: PT;Classification code 10021240;Term: Idiopathic pulmonary fibrosis;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Diseases [C] - Respiratory Tract Diseases [C08] | Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not Available Other descriptive name: PLN-74809-000 Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not available Other descriptive name: PLN-74809-000 Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not Available Other descriptive name: PLN-74809-000 | Pliant Therapeutics Inc. | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 40 | Phase 2 | United States;France;Canada;Belgium;Australia;Netherlands;Germany;New Zealand;Italy;United Kingdom | ||
| 3 | NCT04396756 (ClinicalTrials.gov) | March 3, 2020 | 6/5/2020 | Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis | A Randomized, Double-blind, Dose-ranging, Placebo Controlled Phase 2a Evaluation of the Safety, Tolerability and Pharmacokinetics of PLN-74809 in Participants With Idiopathic Pulmonary Fibrosis (INTEGRIS-IPF) | Idiopathic Pulmonary Fibrosis | Drug: PLN-74809;Drug: Placebo | Pliant Therapeutics, Inc. | NULL | Recruiting | 40 Years | N/A | All | 84 | Phase 2 | United States;Canada |
| 4 | NCT04072315 (ClinicalTrials.gov) | September 9, 2019 | 23/8/2019 | Phase 2a Evaluation of PLN-74809 on avß6 Receptor Occupancy Using PET Imaging in Participants With IPF/ | A Phase 2a Evaluation of PLN-74809 on avß6 Receptor Occupancy Using PET Imaging in Participants With IPF | Idiopathic Pulmonary Fibrosis | Drug: PLN-74809;Drug: Placebo;Radiation: Knottin tracer | Pliant Therapeutics, Inc. | Stanford University | Recruiting | 40 Years | 80 Years | All | 18 | Phase 2 | United States |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2020-001428-33-GB (EUCTR) | 05/11/2020 | 22/06/2020 | A study to assess efficacy, safety and pharmacokinetics of PLN-74809 in participants with primary sclerosing cholangitis and suspected liver fibrosis) | A randomized, double-blind, dose-ranging, placebo-controlled, Phase 2a evaluation of the safety, tolerability, and pharmacokinetics of PLN-74809 in participants with primary sclerosing cholangitis (PSC) and suspected liver fibrosis (INTEGRIS-PSC) | Primary sclerosing cholangitis (PSC) MedDRA version: 20.1;Level: LLT;Classification code 10036732;Term: Primary sclerosing cholangitis;System Organ Class: 100000004871;Therapeutic area: Diseases [C] - Digestive System Diseases [C06] | Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not yet established | Pliant Therapeutics, Inc | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 84 | Phase 2 | United States;France;Canada;Belgium;Austria;Australia;Norway;Netherlands;Germany;United Kingdom | ||
| 2 | NCT04480840 (ClinicalTrials.gov) | July 27, 2020 | 13/7/2020 | Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Patients With Primary Sclerosing Cholangitis (PSC) | A Randomized, Double-blind, Dose-ranging, Placebo-controlled, Phase 2a Evaluation of the Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Participants With Primary Sclerosing Cholangitis (PSC) and Suspected Liver Fibrosis (INTEGRIS-PSC) | Primary Sclerosing Cholangitis | Drug: PLN-74809;Drug: Placebo | Pliant Therapeutics, Inc. | NULL | Recruiting | 18 Years | 75 Years | All | 84 | Phase 2 | United States;Australia;Canada |