Isotopic intravenous [13c]-urea    (DrugBank: Urea)

1 disease
IDDisease name (Link within this page)Number of trials
251Urea cycle disorder1

251. Urea cycle disorder    [ 42 clinical trials,   45 drugs,   (DrugBank: 10 drugs),   4 drug target genes,   29 drug target pathways]
Searched query = "Urea cycle disorder", "N-acetylglutamate synthase deficiency", "NAGS deficiency", "Carbamoyl phosphate synthetase I deficiency", "CPS1 deficiency", "Ornithine transcarbamylase deficiency", "OTC deficiency", "Classic citrullinemia", "Citrullinemia type I", "Argininosuccinic aciduria", "Argininemia", "Hiperornitinemia-hiperamonemia-homocitrulinuria syndrome", "HHH syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 42 trial found
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PhaseCountries
1NCT02670889
(ClinicalTrials.gov)
November 201614/1/2016Urease Inhibitor Drug Treatment for Urea Cycle DisordersManipulating the Gut Microbiome in Urea Cycle DisordersOrnithine Transcarbamylase Deficiency;Argininosuccinate Synthetase Deficiency (Citrullinemia);Argininosuccinic Acid Lyase Deficiency (Argininosuccinic Aciduria);Carbamyl-Phosphate Synthase I DeficiencyDrug: Acetohydroxamic Acid;Drug: Isotopic Intravenous [13C]-UreaNicholas Ah MewData Management and Coordinating Center (DMCC);Children's Hospital of PhiladelphiaNot yet recruiting18 Years60 YearsBoth16Phase 1;Phase 2NULL