DDrare: Database of Drug Development for Rare Diseases

High doses of thiamine y biotin (DrugBank: Biotin, Thiamine)

3 diseases

ID	Disease name (Link within this page)	Number of trials
8	Huntington disease	1
13	Multiple sclerosis/Neuromyelitis optica	0
265	Lipodystrophy	0

8. Huntington disease [ 197 clinical trials, 171 drugs, (DrugBank: 54 drugs), 82 drug target genes, 144 drug target pathways]

Searched query = "Huntington disease", "Huntington chorea"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 197 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04478734 (ClinicalTrials.gov)	January 1, 2021	11/2/2020	Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease	Multicentric Trial on the Use of Combined Therapy of Thiamine and Biotine in Patients With Huntington´s Disease	Huntington Disease	Drug: Moderate doses of Thiamine y Biotin;Drug: High doses of Thiamine y Biotin	Fundación Pública Andaluza para la gestión de la Investigación en Sevilla	Ciberned (Centro de Investigación Biomédica en Red)	Not yet recruiting	18 Years	N/A	All	24	Phase 2	Spain

13. Multiple sclerosis/Neuromyelitis optica [ 3,050 clinical trials, 2,147 drugs, (DrugBank: 348 drugs), 244 drug target genes, 228 drug target pathways]

Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 3,050 trial found

265. Lipodystrophy [ 109 clinical trials, 164 drugs, (DrugBank: 59 drugs), 26 drug target genes, 94 drug target pathways]

Searched query = "Lipodystrophy", "Berardinelli-Seip syndrome", "Lawrence syndrome", "Barraquer-Simons syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 109 trial found